I am desperate... what is your recent experience with prolia

lago

Ask both your oncologist and your dentist. I get my cleaning and exam a week before per my dentist's orders. If I needed work that would be a problem I'm sure my Prolia injection would be postponed so I could get it done.

mysunshine48

What happens to your teeth or jaw with Prolia?

Jerseygirl927

your dentist should know this, in the meantime go to the prolia website for exact details. It's a possible side effect.

SpecialK

I get cleanings done any time but was instructed by my MO to have routine dental work done at the mid-point between injections - so, three months after an injection, which is three months before the next. Invasive dental work, such as an extraction, implant, root canal, etc., potentially raises the risk of ONJ ( osteonecrosis of the jaw) but it is a relatively rare side effect. ONJ is a greater risk with higher or more frequent doses such as those given for bone mets or bone cancer

Sig

Hi, things has not been going the way I planned, I have not started prolia yet due to my ongoing dental problem, unable to really locate the exact place of my pain, so after my first root canal (done my endo) pain was still there, so went to the endo again check my tooth and mentioned that it could be from the adjacent tooth (referring pain) and said probably need a root canal in the adjacent tooth also. So I had my second root canal done two weeks ago, I still have pain but less intense, so went to the dentist who referred me to oral surgeon and he confirmed that I had abscess under my first root canal tooth and it needs to be extracted otherwise the problem can get worse and should be extracted prior to start prolia and I have to wait 4 months after the extraction to start prolia. However I took fosamax for 5 years so I am quite scare of the extraction.

so anyone who was on fosamax and later on had tooth extracted?? if yes how was it?? and how long did you have to stop fosamax in order to have your tooth iextracted??

MinusTwo

Oh Sig, so sorry to hear about your abscess. I did find out the hard way that one tooth can have two roots or even three roots. I had each of the 3 removed separately since "no one knew" up front. Yuck. My pain was finally solved when the 3rd root was discovered & removed.

Sorry, I didn't ever take Fosamax. Hopefully someone else will be able to answer your question.

lago

Sig talk to your doctor about Fosamax but I believe if you've been off it for a while the tooth extraction shouldn't be an issue. Also Osteoporosis doesn't progress like cancer. It's much slower. Waiting 4 - 6 months isn't a big deal.

Jerseygirl927

hi sig, was on fozamax for several years and it did increase bone density. However had to come off because it gave me acid reflux. However you have made me think, I have a tooth that had to be root candled twice. It took Avery long time for the tooth to settle down, I sometimes still get some residual pain in that same area and am constantly having it checked, I am now going to ask my dentist to look into a possible jaw issue with fozamax as a result. I had root canal over 10 years ago. Might not be related but that's my experience. Waiting on prolia for now.

Sig

Thank girls for your input, I did talk to the doctor and oral surgeon and both say I should be fine because I am off fosamax for two years now but still remains with a slight risk, but it scares me anyway, so I was looking to get some feedback from women who have been through the same thing as me and had tooth extracted. I have been pushing the prolia shot since last June, and both doctor and dentist recommend to wait until my dental problem resolved but by the time I get my prolia shot it would be almost 10 months that I should have it and in the meanwhile my bone continue to deteriorate which scare me also. I really would like to know if I will be fine with the extraction, sometime I just feel to take the prolia shot and live with my tooth pain but also I am afraid that my dental problem get worse.

lago

Sig they really do take this SE seriously. In April I had a really bad fall. Hit my chin and needed stitches. My bite was off. My Prolia was delayed 5 weeks. If my bite wasn't back to normal I'm sure it would have been delayed longer. I did have an MRI to see if the jaw was broken when I went to the ER. No brake but they still wanted to wait.

Jerseygirl927

I have had at least 5 fractures in the past 2 years, 1 brake, so I know that I should go to prolia asap, but I still worry about the necrosis of the jaw, maybe a talk with the dentist would help.

lago

Talk with both your doctor and dentist about all the precautions. My dentist wants me to see him before I get my Prolia. That way if there are issues we can delay the Prolia and handle the dental issues.

Jerseygirl927

hope to soon.

murielwhite5

Hi JerseyGirl9, I have osteoporosis of the spine and osteopenia in the hip. My second dexa showed deterioration so I now have to go on treatments for it. I have opted for the prolia 6 monthly injections but don't start till this coming Thursday. Believe me, I am TERRIFIED of the possibility of the jaw problem. When I mentioned in to my dentist on the last visit he told me that dentists DO NOT like these treatments due to the possibility of the jaw problem. I notice a lot of ladies don't have any problems with the prolia so I am keeping my fingers crossed. Best wishes to you all Love Muriel

lago

I've had 3 prolia shots now. No issues. No side effects

Golden01

I am not on Prolia but my MO is requesting approval from the insurance company for me to switch to Prolia. My dentist said that the problems are not as common as they thought at one time. He said the main things are to be sure your teeth are in good shape and you have all dental procedures done before you start. He indicated the problems are most likely to occur if you need a tooth pulled or major dental work. My MO wanted to know about my dental history before we proceeded and said it was important to keep up with regular checkups.

Jerseygirl927

I have had no problem with the 1 prolia shot so far, but I am going to dentist Jan 4 as I think I have a cracked tooth, so an exray is in order and then we will address that issue if need be. My dentist was pretty sure that as long as no major dental work is done everything should be ok, major dental would be scaling gums, putting in stays , things like that, I am hoping nothing major is going on. Will keep you posted. But I would say the prolia has two good features about it. Bone growth, and cancer preventive.

lago

I have my dentist appointment 1-4 weeks before my Prolia injection. I won't even get my calcium tested till my dentist gives me the OK. No major work needed.

Jerseygirl927

went to dentist today, can't find crack,does think there could be a root issue going on, but then I am in the throws of major upper respitoryy infection, so on anti biotics, only took the sore throat away, he said he wants me to wait it out, which I agree, but no tooth pulling on prolia. So his recommendation I will wait it out, if I avoid the tooth, there is no issue, so that's my story for now.

lago

Jerseygirl927 I had a really bad fall just before I was supposed to get my last Prolia. Ended up with 3 stitches on the bottom of my chin and jaw as dislocated due to swelling. I did get ex rays and saw the jaw wasn't broken but we waited 5 weeks till the swelling went down and my jaw was back in place. This is why I go to the dentist just before my Prolia shot. If there is an issue we can deal with the teeth and push back on the Prolia shot.

windingshores

Wait, I know Reclast and Zometa help with cancer, but I didn't know Prolia did-? Can someone tell me about this?

MinusTwo

WindingShore - if you read through these two pages of posts, there are several women who feel the Prolia can be a preventative to bone mets. If you google Prolia & Bone Mets, there are a number of good articles about Prolia as part of the treatment for bone mets. Personally I haven't taken Prolia yet. My endodontist wants me to wait as long as possible due to the SEs

Jerseygirl927

there is a great article on the denusamtrab study. It was informative and re-assuring, so if prevents the recurrence of cancer, I am in." I couldn't copy the link but it's done by an Australian dr.

ChiSandy

I think that’s what Dr. Favus, the "Bone Whisperer” at U of C, wants to put me on. It’s probably the least onerous of all the bone-preserving drugs. After I see my MO and discuss it with her, I will see him.

Sydneyluv

hummmm. I started Prolia last summer due to arimidex caused osteoporosis and 2 broken bones. I consulted with 3 different specialists before I started because I had the concerns discussed above. Although my primary care doc was concerned too, none of the specialists were. They thought the jaw dental problems were way overblown from early on as did my dentist and they thought Prolia was the best osteoporosis drug now available. I did get a root canal and crown completed before my first injection. I have had no side effects whatsoever

Jerseygirl927

I have been looking for days for an article I read about bone growth with something other than something, fosomax or denusamtrab (prolia) . It began with bromo?.. Something, can't find it, anyone else might know what I am talking about, I think it was a natural substance but I can't find the article again

lago

I serving of prunes a day has shown to help grow bone a little in some studies. Ruthbru knows of t his study

Kathy044

News from the NOF about prunes last June 2015.

http://nof.org/news/5521

On another note I had my sixth Prolia injection on Monday. I woke this morning with slight swelling in my LE arm, admittedly I went to exercise classes the two previous days and have been using the iPad more than I should be but this reaction is unusual for me. I am not concerned as this should be temporary.

I noticed previously after a Prolia injection that a rash (contact dermatitis not related to the Prolia, I think) took longer to disappear on the LE arm than on the other, had an appointment with my fitter for a new sleeve, it was a hot day, when I removed my old sleeve the rash had turned a bright cherry red. My fitter immediately got out her sharpie and drew a line around it but I knew it was not an infection but the heat. I later learned that Prolia acts not just on the bone surfaces but on tissues such as the casing covering lymph nodes too, which can explain a lot of things.

Kathy

MinusTwo

Kathy - did you have the injection in your arm?

I just found out yesterday that my hip Femoral Neck now definitely shows osteoporosis and the doc wants me to start Prolia. Aside from the concerns of my dentist and periodontist, I made sure that shots can be given in the butt or hip & she agreed. No way to I want to aggravate the LE. Doc said the side effect she sees most often is cellulitis.

Unfortunately my teeth are not in great shape. Seven top front teeth suffered radiation decay (and from the chemo dry mouth). I've already had one break off at the roots and the others could break at any time. My first & only implant took 4-5 months for the bone to grow solid around the implant, so you can imagine how un-excited i am about Prolia. Sigh.

SpecialK

Prolia is a subcutaneous injection, so should be able to be given in a variety of locations.

winding - here is some info about the benefit of Prolia and breast cancer from ASCO 2015 - I think that might be what you were referring to:

http://www.oncologypractice.com/specialty-focus/breast/single-article-page/asco-adjuvant-denosumab-halves-fracture-risk-for-breast-cancer-patients-on-ais/cc415bed88dbd8d849def76171de6f12.html