Breaking Research News from Breastcancer.org

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Exercise Before and After Breast Cancer Diagnosis Improves Survival, Reduces Recurrence Risk
June 4, 2020
Doing the minimum amount of recommended exercise per week — 2.5 hours — both before and after being diagnosed with breast cancer with a high risk of recurrence is linked to better survival and a lower risk of recurrence. Read more...

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Accelerated Radiation Therapy for 1 Week Offers Same Benefits as 3-Week Schedule for Early-Stage Breast Cancer
June 5, 2020
An accelerated schedule of radiation therapy of 5 treatments over 1 week seems to offer the same benefits as a schedule of 15 treatments over 3 weeks for early-stage breast cancer. Read more...

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Experimental Veliparib Improves Outcomes for People With BRCA Mutation and Advanced-Stage HER2-Negative Breast Cancer
June 8, 2020
The PARP inhibitor veliparib improved progression-free survival for people with a BRCA1 or BRCA2 mutation diagnosed with locally advanced or metastatic breast cancer that was either hormone-receptor-positive and HER2-negative or triple-negative. Read more...

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Can Satisfying Romantic Relationships Lead to Better Health for Breast Cancer Survivors?
June 9, 2020
Women who've been treated for breast cancer who are in satisfying romantic relationships may have a lower risk of health problems after treatment because the relationship eases stress, which lowers blood inflammation markers. Read more...

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Young Adults With Early-Onset Cancer May Benefit From Genetic Testing
June 24, 2020
People age 18 to 39 who are diagnosed with cancers typically seen in older adults, such as breast cancer, have a higher-than-expected risk of having a genetic mutation linked to cancer and so might benefit from genetic testing. Read more...

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FDA Approves Phesgo: Perjeta and Herceptin Combo Injection for HER2-Positive Breast Cancer
June 29, 2020
The FDA has approved Phesgo, a fixed-dose injection of Herceptin (chemical name: trastuzumab), Perjeta (chemical name: pertuzumab), and hyaluronidase-zzxf to treat all stages of HER2-positive breast cancer in combination with chemotherapy. Read more...

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Cancer Survivors Overestimate Quality of Their Diets
June 29, 2020
Most people who have been diagnosed with cancer think they eat a healthy diet, but a study found that their diets were generally poor. Read more...

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Expanding Medicaid Linked to Fewer Women Diagnosed With Later-Stage Breast Cancer
July 8, 2020
Expanded Medicaid coverage through the Affordable Care Act was linked to fewer women diagnosed with later-stage breast cancer, as well as a reduction in the number of women diagnosed with breast cancer with no insurance. Read more...

PeggySull

As a BC survivor, these research articles are now the most important part of my membership! Please do not stop!!!

Moderators

We won't stop, PeggySull! We're glad to hear that. Thank you!

The Mods

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In Men, Characteristics of BRCA1-Linked Cancers Differ From Those of BRCA2-Linked Cancers
July 13, 2020
A study suggests that there are differences in the characteristics of cancers linked to a BRCA1 mutation compared to those of cancers linked to a BRCA2 mutation in men. Read more...

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Heart Problems Seem to Increase Risk of Worse Outcomes After Early-Stage Breast Cancer
July 21, 2020
The risk of breast cancer recurrence and death due to breast cancer increased in people who had a heart attack, stroke, or heart failure after being treated for early-stage breast cancer. Read more...

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Chemotherapy May Benefit Older People With Estrogen-Receptor-Positive Breast Cancer and Other Health Problems
July 23, 2020
People age 70 and older diagnosed with estrogen-receptor-positive, HER2-negative, node-positive breast cancer who had other health problems who were treated with chemotherapy after breast cancer surgery had better survival than people who weren't treated with chemotherapy. Read More...

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COVID-19 Pandemic Delayed Breast Cancer Screening in Many Parts of the United States
July 30, 2020
Breast cancer screening has been delayed as a result of the COVID-19 pandemic. Read more...

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Pregnancy After Breast Cancer Seems Safe for Women With BRCA Mutation
August 5, 2020
Women with a BRCA1 or BRCA2 mutation who become pregnant after being treated for breast cancer don't have a higher risk of recurrence and their babies are healthy. Read more...

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Did Expanding Medicaid Reduce Differences in Breast Cancer Death Rates Between Black and White Women?
August 6, 2020
Expanded Medicaid coverage through the Affordable Care Act didn't seem to reduce the disparity in breast cancer death rates between Black and white women. Read more...

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ESMO Experts Release Recommendations on Managing Cancer Care During COVID-19 Pandemic
August 8, 2020
Recommendations from a European Society for Medical Oncology expert panel say doctors should not stop or delay any type of cancer treatment that might affect a person's overall survival and that all people diagnosed with cancer are not automatically at high risk for serious complications if they do get COVID-19. Read more...

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Fewer Breast Cancers Being Diagnosed During COVID-19 Pandemic
August 18, 2020
Far fewer cases of breast and five other cancers are being diagnosed during the COVID-19 pandemic. Read more...

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Breast Cancer Surgery Delays Don't Affect Survival in DCIS, Early-Stage Estrogen-Receptor-Positive Disease
August 19, 2020
Delaying breast cancer surgery for people diagnosed with DCIS or early-stage estrogen-receptor-positive invasive disease doesn't seem to affect survival. Read more...

ShetlandPony

Beyond the headline, it is important to note that “Increased time to operation was associated with increased odds of pathologic upstaging in DCIS patients...but not in patients with invasive cancer, irrespective of initial treatment strategy. No difference in OS was seen by time to operation in DCIS or NET patients.“ NET patients means the people with early stage invasive breast cancer were given neoadjuvant endocrine therapy. In other words, they took anti-estrogen therapy while waiting. That seems a very important point for anyone facing a delay. It seems to me that if you are facing a delay you should ask about starting hormonal therapy while waiting, based on this study.

2019whatayear

that's huge Shetland thanks for pointing it out.

Moderators

Starting Breast Cancer Screening at Age 40 Instead of 50 Saves Lives
August 22, 2020
Starting screening mammograms at age 40 instead of age 50 saves women's lives. Read more...

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Survey Suggests COVID-19 Pandemic Led to Delays in Care for Nearly Half of Breast Cancer Survivor
August 27, 2020
The early weeks of the COVID-19 pandemic caused 44% of breast cancer survivors to have a delay in care, according to an online survey. Read more...

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Intraoperative Radiation Therapy During Lumpectomy Seems as Good as Traditional Whole-Breast Radiation Therapy for Early-Stage Breast Cancer
September 2, 2020
A single dose of radiation therapy given during lumpectomy surgery offered about the same outcomes for early-stage breast cancer as traditional whole-breast radiation therapy given after surgery. Read more...

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Radiation for Childhood, Young Adult Cancer Linked to Worse Survival After Premenopausal Breast Cancer
September 14, 2020
Women diagnosed with childhood or young adult cancer treated with radiation therapy who developed breast cancer before menopause were more likely to die from breast cancer compared to similar women who didn't have childhood or young adult cancer. Read more..

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Veliparib Maintenance After Chemo Slightly Improves Outcomes for Metastatic HER2-Negative Breast Cancer With BRCA Mutations
September 14, 2020
People diagnosed with metastatic HER2-negative breast cancer with a BRCA1 or BRCA2 mutation treated with experimental veliparib and chemotherapy lived about 2 months longer without the cancer growing if they continued on veliparib after stopping chemotherapy. Read more...

LillyIsHere

Differential impact of prognostic parameters in hormone receptor‐positive lobular breast cancer

https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncr.33104

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Adding Verzenio to Hormonal Therapy After Surgery for Early-Stage Breast Cancer With High Risk of Recurrence Reduces That Recurrence Risk
October 8, 2020
Study shows adding Verzenio to hormonal therapy after surgery for early-stage hormone-receptor-positive, HER2-negative breast cancer with a high risk of recurrence lowers that recurrence risk by about 25%. Read more...

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Piqray Improves Overall Survival for Advanced-Stage Hormone-Receptor-Positive, HER2-Negative Breast Cancer With PIK3CA Mutation
October 16, 2020
Postmenopausal women and men diagnosed with advanced-stage hormone-receptor-positive, HER2-negative breast cancer with a PIK3CA mutation lived about 8 months longer when treated with the combination of the targeted therapy Piqray and the hormonal therapy Faslodex compared to Faslodex alone. Read more...

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Trodelvy Improves Outcomes for Previously Treated Metastatic Triple-Negative Breast Cancer
October 20, 2020
Compared to standard chemotherapy, Trodelvy offered better outcomes for people diagnosed with previously treated metastatic triple-negative breast cancer. Read more...