TRIPLE POSITIVE GROUP

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  • KimCee
    KimCee Member Posts: 178
    edited December 2017

    I know Hap, I am staying away. I do not have one of those bottles but have been looking to get one. I do a smoothie most mornings, banana, blueberry, strawberry, with coconut or almond milk. That is a good amount of fluid too. I feel great, oncologist was so pleased that I have zero side effects except for man sized hunger and being bald. So thrilled to hear you are beginning to feel better.


    Cherry, yes, it is probably the shots. I had pain for a day when I had them 18 years ago. Hurt to even take a shower. Towards the final treatment, oncologist stopped the shots because they were increasing counts too much. Back then it was 10 neupogen shots, once a day for 10 days. What a nuisance. Hope you feel better soon.

  • Binniebin
    Binniebin Member Posts: 87
    edited December 2017

    Kim cee, I have pre-existing liver issues which they don't have a cause for , except Gilbert's which only effects the bilirubin. Pre chemo I went organic, cut processed food, reduced fat and sugar intake, no alcohol. I hadn't asked oncologist what my liver enzymes were in the first test she did ( too much other stuff to focus on ) but when I later sawmy numbers 2 of the enzymes were back to normal levels, had been up for a few years. So my mini liver detox had worked quite well for me. Maybe try it. Also canned food from overseas can have lots of chemicals in them. Unfortunately my levels were in the high 200's after 1st dose along with Iv antibiotics. So 2nd dose adriamycin was reduced a little. I'll find out Wednesday if they've come down enough for full dose cycle 3. Good luck with your test.

  • PoseyGirl
    PoseyGirl Member Posts: 359
    edited December 2017

    Hi Ladies,

    I hope you're all doing well.

    KimCee, I'm sorry about your feelings around your liver. I personally just went through a situation re: my liver and got a clear scan on it. I'm so thankful you have some knowledgeable people here to turn to on that score. It truly sucks to be so scared about things. I have another thing absolutely freaking me out.

    WhyWhy, I totally get your feelings. They are so normal, and yet since you are one person all on your own, it can feel very isolating. After all, it's totally new and we have to ultimately face it all on our own. But then, there are others like us and that is why this groups is so special. I hope you find as much support, information and comfort as I have here.

    So, on the topic of freaking out, I am going through something else now. I noticed a week ago or so that I have a little pain or ache at the top of my thoracic spine when I bend my head right back or forward. I sometimes feel a little ache when I'm just sitting there too. I started feeling very anxious about it, so I called in and spoke to a nurse. She told my oncologist and they are going to order up a bone scan. Apparently, in my last bone scan - which was July, 2016 - they saw what they called 'likely degenerative changes'...some slight uptake. I know that these were not noted on my two bone scans in 2016. So of course I am freaking out. I called back in and spoke to a very good nurse there. She said she's not concerned at all. I have a friend who recurred in the summer with mets to her cervical spine. She had had a bone scan (I think it was a bone scan) back in January that said the same - likely degenerative changes. And then months later, she had significant pain in her neck. They finally gave in to do another scan for her and found the mets. So I told the nurse I'm freaking out about that (because of my friend's experience) and she said that I should not compare, etc, and so forth. She was being very supportive and straight forward, so I have no complaints with her. But I'm so scared. What are the odds of me developing degenerative changes in the 8 months since I'd had the previous scan?? Does that actually happen and create some discomfort?? Doesn't it just seem too coincidental that I develop degenerative changes after I'm done my main treatments (chemo, surgery, radiation)? I was still on Herceptin at the time of that scan (almost at the end, though). After my Zometa infusion this week, I felt the pain was worse in that area for the day after, which then freaked me out more, as I know Zometa can intensify pain in damaged spots for a brief period. My nurse said that this would happen with any area of weakness in the body possibly.

    Another fact that sends me off is the fact that apparently, degenerative 'wear and tear' doesn't typically happen in the thoracic spine. For me, it's at the very top, just under the cervical spine.

    I have read so much about it being tough to tease out malignancy versus degenerative stuff in a bone scan (well, I haven't read a ton, but I saw a few sources). Does anyone hear have any experience that would suggest otherwise? They didn't make any scary note on the report and said 'no evidence of metastatic disease'. But at this point, I'm starting to feel it's inevitable.

    The other thing is that three weeks ago, I started getting chills. Mostly in the morning and at night, but then all the time. I still have them. I've talked to both my GP and my nurse about this, and nobody sees any link between my chills and cancer (unless it were a fever). But now I'm really questioning that, wondering if my body is starting to react to the foreign thing going on in my body?

    Sorry to go on - I'm having a terrible time with this and have no clue when they'll get me in for a bone scan - I'm sure within two weeks, but I don't know when.

  • Binniebin
    Binniebin Member Posts: 87
    edited December 2017

    posey girl, I hope they get you in for a bone scan quickly, the waiting is horrible. It must be hard to stay positive after your friends experience.

  • Cherry-sw
    Cherry-sw Member Posts: 997
    edited December 2017

    PoseyGirl, please do not panic, a lot of things can happen in thorasic spine, spondylos for example and it can be painful, age specific detenerative activity is common there. I know how awful and agonizing the waiting can be, I hope they will order it as soon as possible. It is a good sign the doctors are not concerned. Hang in there,Cherry

  • KimCee
    KimCee Member Posts: 178
    edited December 2017

    Posey, I have no answers for you but can relate to how you are feeling. The waiting is the worst, I hope they get you in soon. During my first rodeo with BC, I remember strange pains that lasted a while and had me crazy with concern. It was definitely related to tamoxifen, and went away after I switched to femara. It could most definitely be cells regenerating after the poison our body has had to deal with. Hang in there, sending you a hug.

  • PoseyGirl
    PoseyGirl Member Posts: 359
    edited December 2017

    hi ladies, thanks for being there...

    I'm on an AI, Hap...Letrazole. I think I started that in May. In July I had this bone scan which showed the degenerative change comment (which was not shared with me and which did not appear in November 2016). Chemo was done end of November 2016.

    Cherry, thanks for your thoughts...I became even more upset when I saw that the Thoracic spine is apparently NOT a common spot for degeneration.

    I am basically starting to curl into a ball here. And why chills for three weeks???

  • deni1661
    deni1661 Member Posts: 463
    edited December 2017
    Sorry playing catch up....whywhy, sorry you have to join us but this is a great place for info, support and inspiration. Ask lots of questions and seek a second opinion if needed to gain complete confidence in your treatment plan. I'm 15 months from diagnosis and getting used to my new normal. You will get there too.

    Posey, I understand the fear as every new symptom can be cause for anxiety. I have had tailbone pain for 9 months now. Had an MRI and they didn't find a cause, assumption is the pain is due to AI. My body aches all the time and I try to keep moving which seems to help. I hope you can get a bone scan soon, the waiting for an answer is the hardest. Sending hugs and prayers you find a solution soon.

    KimCee, sorry to hear your liver enzymes are high. Mine were high a few times, once after surgery, other times probably due to a supplement or Tylenol. I never got a clear answer on this symptom either. I drink warm lemon water and a detox tea every day and lots of water. My MO said flushing the liver out is so important to get all the drugs out our system and build up the immune system. Praying your blood work is much better next week. Hang in there

    Hapb, so glad to hear you're feeling better these days.

    Moody, congrats on getting the TEs out and implants in! It really sucks your surgeon was so late, how inconsiderate. Waiting is so stressful. I'm grateful my PS is always on time or early. I hope the scalp itching is gone and your recovery from surgery is going well

    I had my 3 month check up Wednesday; mammogram on right was clear, blood work good. I was a nervous wreck earlier this week, couldn't shut off thoughts of recurrence. I had my revision surgery Thursday and port removed. I have 5 wounds to heal but thankfully no drains. I am happy my reconstruction project is done and I can move forward.

    Wishing all of you a pain free, calm and peaceful weekend!

  • Lita19901
    Lita19901 Member Posts: 211
    edited December 2017

    Posey, have you had your thyroid checked lately? Hypothyroidism can mess up your body temperature, which might account for the chills

  • moodyblues
    moodyblues Member Posts: 470
    edited December 2017

    Posey, most of us have been there, freaking out about a pain we have that lingers.  We research and then our fears grow and we think about it more than ever, I hate that BC has done this to us.  The only offering that I can give is to get busy with your mind so that you don't have time to think about it.  Not so easy I know.  Believe me.  I pray a lot and keep my mind busy as I can.  

    Thinking of you,  Melanie

  • Suburbs
    Suburbs Member Posts: 429
    edited December 2017

    Deni1661, quite a few milestones in a short period of time. Good news and I hope you recover quickly from stage 2. Congratulations!

    Cherry-sw, taking Claritin a day or two before neulasta is supposed to minimize the side effects. I read this in my chemo group thread. Hope you feel better soon.

    Poseygirl, I hope you have your test soon and everything is ok. My fight song during chemo was "pixie dust and unicorns" and it worked. So, I'm sharing both with you and sending lots of positive thoughts along with them. Hang in there. Please keep us posted

  • moodyblues
    moodyblues Member Posts: 470
    edited December 2017

    Deni, My itching has subsided, thank goodness!  I am a bit sore from the surgery but, I am sure in a few days I will feel good again.  I was beginning to feel normal again and now I am limited until I heal up.  Grateful for my taste buds being back to normal and some of my strength returning.

    Ladies if we could just go back pre cancer.  If they would/could have told us we were at risk or something, I would have removed them in a skinny minute.  Just thinking....just saying.  Shouldn't all women be tested early in life to see if we have 'the' gene, it would have to be cheaper to remove them than to pay for the treatments or even worse for women to die from this.  Just thinking.

  • Cherry-sw
    Cherry-sw Member Posts: 997
    edited December 2017

    PoseyGirl, but it is according to my PT, spondylos can be painful she said to me and it is common to have muscle knots there, nervous breakdowns can cause that thorasic spine locks. I am doing daily exercises to unlock it, PT once a week, I did both X-ray in August, and bone scan two weeks ago, in both cases the report came back telling that there some worn parts on the bones which is common for our age they said, and then I have this spondylos too. Do no work yourself up, my heart was breaking when I red your post, I know exactly how it feels, let us wait until the scan and the results. I am holding my thumbs. Hugs,Cherry

  • Cherry-sw
    Cherry-sw Member Posts: 997
    edited December 2017

    deni1661, great news that you are done, you must feel such a relief, it is a big milestone

  • Cherry-sw
    Cherry-sw Member Posts: 997
    edited December 2017

    Thank you all for suggestions, got up in the morning, still sore everywhere, it is time for the next shot. I went to my local care provider for the first one and the elderly nurse, this kind that likes to tell people what to do, showed me how. I believe I annoyed her, she said these shots were easy to do, but I said how would I know? She said that diabetics are doing them and I said that I was not one, she then asked whether I red the instruction and I looked away and shrugged my shoulders. Just thought that for a shot worth over 120 Euro of taxpayers money they could at least show me how to do it. I mean she did it and I still did it wrong yesterday, the needle did not pull in when I pulled it off, hope it will work out today.

    KimCee, the liver enzymes can be very volatile, something I learnt when our eldest girl was trying different meds for her acne, she did not get to try one at all at first because her values were up, and she was like maybe 17 at a time. The doctor said that sometimes as much as some fat food can cause the values to go up. In a month they tried again and everything was fine.

    moody, the majority of women who have bc genes do not get bc according to my clinic, there is a higher risk but it does not mean they will develop it Cherry

  • whywhy
    whywhy Member Posts: 36
    edited December 2017

    For people getting Pertuzumab, how long typically will it be? From the guideline Vicky posted and my MO, it stops when chemo stops. I ready somewhere in a medical paper that it should be a year. Anyone getting it for a year? Thanks!

  • SpecialK
    SpecialK Member Posts: 16,486
    edited December 2017

    posey - I had degenerative disk issues at L4/5 nine years prior to diagnosis. Enough to cause significant back pain, particularly when sitting. Due to sudden onset hip pain in late 2014 I had bi-lateral hip and lumbar MRI, and a DEXA. My oncologist favors MRI when looking for bone mets, and the DEXA was done to check for avascular necrosis due to Prolia. DEXA was fine, the MRI did not reveal bone mets, but did show increased degeneration in both the lumbar spine at L3 and the thoracic spine, as well as bone spurs in the thoracic. The hip pain was being caused by an injury that I did not realize I had - we had moved DD to a third floor apartment and while I was careful to carry light things due to lymphedema, I made a LOT of trips up and down the stairs. I had a seizing pain down the front of my thigh and stopped for the day, the pain went away completely a few minutes later, but a week later the hip pain started. The MRI showed multiple stress tears in the gluteus medius - the muscle that goes across the hip, as well as trochanteric bursitis and fluid in the hip joint. Intensive PT for the better part of a year resolved this totally, but I had pain for most of that time. I don't know if you can opt for a different type of imaging - either MRI or a PET, bone scans are notorious for showing everything, but problematic in delineating what those things are.

    cherry - start taking Claritin (regular, not Claritin with decongestant) or generic loratadine 10mg and see if that helps with your pain. Loratadine, while an allergy antihistamine, is thought to relieve the edema that build up in the bone marrow while it is generating new white blood cells. People have found that combining loratadine and Aleve (naproxen sodium), which is a longer acting NSAID, to help with pain from the blood cell boosting injections.

    whywhy - Perjeta for 6 cycles is standard for early stagers, generally those receiving it for a longer period are node positive or have some other additional risk factor, and I have not seen many who have continued for the full year. As with any of these decisions you have to weigh risk versus reward, so your oncologist should explain what is best for your individual situation as none of these treatments are without potential for collateral damage.

  • Cherry-sw
    Cherry-sw Member Posts: 997
    edited December 2017

    Thank you SpecialK, I only saw one sort of Claritin at the pharmacy, the one you use when you are allergic, I will talk to my clinic tomorrow, otherwise it got a bit better compared to this morning Cherry

  • KimCee
    KimCee Member Posts: 178
    edited December 2017

    Hap, will wait on SpecialK, but I seem to remember Zometa being linked to kidney disease. I am on Prolia. Not super positive though

  • deni1661
    deni1661 Member Posts: 463
    edited December 2017

    cherry, I hope your pain is better today. I would expect a nurse to take as much time as necessary to show you how to do the shots.

    Moody, praying you feel better each day and recovery is smooth. I too was feeling almost normal, now I have 6 different incisions that need to heal. I was a little shocked this morning when I changed the dressings and saw the new scars.

    whywhy, I did a full year of Herceptin and Perjeta but I was part of a clinical trial.
  • SpecialK
    SpecialK Member Posts: 16,486
    edited December 2017

    hap - zometa is zoledronic acid, or Reclast, which is a bisphosphonate that is given by IV. Bisphosphonates, both IV and oral (oral drugs include Fosamax, Boniva, Actonel), affect bone and its density by binding to minerals and interfering with osteoclasts, the bone cells that absorb bone tissue. Spontaneous fracture seems to occur more frequently with bisphosphonates than Prolia as the bone is left less elastic. Prolia is a monoclonal antibody, like Herceptin, that acts by slowing down the speed at which old bone resorbs until the new bone creation can catch up. In studies Prolia increased density by a greater percentage, although I don't think it is all that much of a difference. Because Prolia is a more expensive drug, some oncologists start patients with a bisphosphonate and if it is not tolerated then insurance is more likely to pay for Prolia. Both drugs have the potential for flu-like side effects at the time of injection, but I have been on Prolia since early 2012 and had no issues at all. Both bisphosphonates and Prolia are thought to make bones less hospitable to bone mets by increasing density.

  • PoseyGirl
    PoseyGirl Member Posts: 359
    edited December 2017

    Moody, KimCee and others, thanks for understanding how I feel.

    SpecialK, a few questions...do you think it's odd that last year when I had two bone scans that showed no uptake in this area, that suddenly - 8 months later - I do have uptake? Doesn't that seem suspicious given I am finished treatment? And also, is it weird that I am feeling achy and some pain in this area? Don't most degenerative changes in the spine basically go unnoticed? I'm freaking out that something was seen on the last scan and now I'm feeling something. Also, why didn't they decide to pursue other imaging if this area was seen and if specificity is lower? They never even told me about this slight uptake back in July when I got the scan. And the reason I had the scan is because I was feeling creaking in my neck and tingling down my arm!

    Hapb, I had radiation to my right side and in the armpit. I don't think the radiation would have touched the T1 - T3 area of my spine, but of course I'm not sure about that? I finished radiation in February of 2017.

    I started Zometa in May and AI in May too I think. While I get joint stiffness (much less than you, Hapb), this is different as it is something that was seen on a scan prior. So that's why I'm spinning here.

    Thanks, all...

  • Dannajae
    Dannajae Member Posts: 40
    edited December 2017

    Hi Everyone,

    I read everything you all discuss, but between work and recovery, I don't have a lot of energy to post. I truly appreciate your acknowledgments of my posts and help when needed. I'm sorry I can't always reciprocate. I'm halfway through my Taxol/Herceptin. 6 more weeks, and then 9 more Herceptin treatments that will be every 3 weeks. My PA summed up my side effects by saying that nothing was awful, but I have a lot of "stuff." I have a little nausea, itchy dry skin (scalp), acne, fatigue, insomnia (on chemo night), occasional body pain and headaches. I'm not terribly sleepy (except the Benadryl makes me sleep through chemo), but I just feel tired like I can't physically move sometimes.

    The worst two things I think are the diarrhea and my taste buds. Everything tastes awful. Ironically, I'm gaining weight, but I think that's the steroids. It's only been after treatments 5 and 6 that food tastes so bad I'm actually eating less or not wanting to eat.

    Any ideas to help with my taste buds?

    Thanks again. Love you guys.

  • Dannajae
    Dannajae Member Posts: 40
    edited December 2017

    p.s. I think someone was discussing the length of time between surgery and chemo. Mine was more than 90 days. I had my lumpectomy 7/13, but then I got cellulitis which took time to heal. Then I needed genetic testing because as an Ashkenazi Jew, I had the higher possibility of BRCA genes (luckily all genetic markers were negative). After that, I had brachytherapy, and finally they had to have time between the radiation and chemo. My MO said the window should be no more than 90 days, and I was just barely past that mark.

  • SpecialK
    SpecialK Member Posts: 16,486
    edited December 2017

    posey - my degenerative changes at L4/5 that began long before breast cancer were discovered due to pain - I had the initial MRI because I was in so much pain I could not stand up straight. So, whether degenerative changes cause pain is definitely an individual thing. As far as something showing up, when it didn't before, just means it wasn't there, or wasn't seen. Imaging is not foolproof, but I don't know if it is necessarily suspicious. Every PET I have had notes the uptake in my lumbar, and now I have uptake in the thoracic as well, but none of it is bone mets - it is all crumbling due to age. As far as an area of uptake not being mentioned to you at the time - this is why I always get the report copies. I think you should ask for either an MRI or a PET to delineate this area with a different imaging modality, not sure a regular bone scan is definitive enough and I think corroboration with another type of scan would be good to have. I know you are worried and you need a better answer than you have received so far.

    dannajae - unfortunately because you are on weekly chemo your taste buds may not recover until you are done, but I found that varying foods appealed at different points. Things that were cool and smooth felt better the further I went along - melon, smoothies, yogurt - stuff like that. Salty tasted good to me too. Try using plastic utensils also, sometimes the metal utensils gave off a weird taste. I also forced myself to eat red meat to keep my hemoglobin up but it tasted like oddly textured cardboard. I just tried to roll with it.

  • Lita19901
    Lita19901 Member Posts: 211
    edited December 2017

    Regarding the window of time:

    I've read the research that says outcomes are better if there isn't a big time lag but Ijust don't understand this so I hope someone can explain it.

    Suppose I had skipped my mammogram this year so the cancer was in there percolating for 12 more months before it was diagnosed? Does having a biopsy or surgery stir something up so that the cancer becomes more active?

  • SpecialK
    SpecialK Member Posts: 16,486
    edited December 2017

    lita and hap - here is thestudy often cited that explains the 30 day optimal window to begin chemo adjuvently - read beyond the initial abstract to the text and there is info regarding why the timing can make a difference in recurrence risk.

    http://ascopubs.org/doi/full/10.1200/JCO.2013.49.7693

  • moodyblues
    moodyblues Member Posts: 470
    edited December 2017

    Deni,  luckily I only have the one incision to heal and a week out from surgery, it looks pretty good.  Hope that your incisions heal quickly and cause you little discomfort.  I still have discomfort where those darn drain tubes were sewn in during my mastectomy....it is so tender there.

  • Lita19901
    Lita19901 Member Posts: 211
    edited December 2017

    Specialk, Hap - Yes, this was study I referred to in my earlier post. Interestingly, the authors say they don’t understand the “why” behind their results, either.



  • deni1661
    deni1661 Member Posts: 463
    edited December 2017

    dannajae - gentle hug, hope your appetite and energy improve each day. Hang in there

    moody - my drain site still hurts too, I thought it was just my imagination. I'm guessing it takes a long time for these incision sites to feel "normal" if there is such a thing. Nausea is quite bothersome for me right now...I'm assuming it's a reaction to the anesthesia and other drugs that were loaded into my body the last couple of days. Hope your recovery continues to go well

    Posey, I hope you get answers soon. Waiting and wondering is stressful on the body and you don't need that!

    Hapb, I thought yoga would help with aches and pains. Now you have new pain, that stinks. It seems like there is always a domino effect with our bodies. We have to keep trying I guess to find something that works . But it sure is frustrating

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