oophorectomy

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samcid
samcid Member Posts: 19
edited June 2014 in Complementary and Holistic Medicine and Treatment
oophorectomy
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  • samcid
    samcid Member Posts: 19
    edited January 2008

    Hello all, new to the site.  Good place to be!

    Has anyone else considered oophor as an adjuvant therapy instead of chemo?

    newly diag'd 11/2/07 with idc .7cm, er + (er 16%, pr 56%), her2 -, no nodes, mod-diff...

    am not a fan of chemo, or tamo...

    discussed this with my onco who seemed to support the treatment program of ooph, rad and AI's

    i also wonder if anyone can tell me what the % of hormone levels correlates to???

    many thanks....

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  • NativeMainer
    NativeMainer Member Posts: 10,462
    edited January 2008

    The percent refers to the number of tumor cells that tested positive for the estrogen or progesterone receptor.  The higher the % of receptors the more helpful an estrogen blocker like tamoxifen or on of the AIs will be.  There is some research that indicates that the higher the ER/PR % is the less likely chemo will be helpful. 

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  • awjkej
    awjkej Member Posts: 133
    edited January 2008

    Hi

    I am her2/neu +++, ER+/PR+, orig diagnosis in Jan 03.  Bone mets diagnosed Fall of 04.  My hormone receptor percentages were both in the high 90's.  I had an oophorectomy in the Fall of 2005, but after I had progressed in my bone mets.  I had been on zoladex which stopped my periods prior to that, but wanted the oophorectomy since I was experiencing some progression as shown by PET/CT scans.  I wanted the oophorectomy so that I knew there was no chance of estrogen coming from my ovaries.  I have also heard of many women have the oophorectomy for just the reasons you stated.

    I have done chemo, radiation, and have had breaks from it when my mets responded well.  I am currently NED, still on xeloda/tykerb, zometa, and aromasin.  I also incorporate a CAM regimen along with traditional treatment.

    Good luck with your decision!

    Hugs,

    Anne

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