Who takes Femara?
Comments
-
My Onc just changed me from Tamoxifen, to Femara. What does this do that the Tamoxifen didn't. I have gone through menopause that is why he changed it.
The cost is way different too......What side effects does it have?
Any feed back will be appreciated.
-
Here is something I found posted on another message board....
I have been on Femara for the past 14 months. I have trouble sleeping, experience excessive sweating when nobody else is even the least bit hot, get up from a chair and walk like an old lady, knees kill me when I attempt to go up or down stairs and have gained weight and cannot seem to lose it. Anyone else experience this on Femara? I am afraid not to take it because of the alternative.
-
If it's any comfort---the above quote about Femara sounds like me on Arimidex. They changed me to Femara and things are much better. Still rarely creaky and sometimes can't sleep but, at my age (63) can't blame that entirely on Femara.
Femara works by knocking off any estrogen your body may still be producing---it's in much lower amounts once we go thru menopause but our bodies still produce/release small amounts.
We react to different meds in different ways---I'm thankful we're not stuck with just one choice. -
Hi Mary,
I've been on Femara for 10 months. Here's what I was told about how it all works: Tamoxifin acts on, changes, estrogen produced by your ovaries, whereas Femara and the other AIs prevent your adrenal glands, where estrogen is made after menopause, from producing any (or much) estrogen. Femara and other AIs are different from Tamoxifin in that they don't interact directly with the cancer. For that reason, doctors think they may be more effective in the long term than Tamoxifin, as cancer cells can eventually mutate to the point where they're feeding off the Tamoxifin instead of estrogen. (That's why Tamoxifin is only prescribed for 5 years.) I believe that Femara is considered slightly better than the other AIs, but that may be more hype than fact. It does cost more.
I have the most common side effects--joint pain and hot flashes. I haven't gained weight. The joint pain is the hardest SE for me. I can walk OK, but going up and down stairs, getting out of bed, getting up from chairs, etc. are all difficult. Some days are worse than others. Anti-inflammatories are usually prescribed for the joint pain. The pain was worse in the first couple months; it's lessened a little since then. Supposedly for some women the pain subsides significantly with time.
Because AIs cause some bone loss, your doctor will probably prescribe Fosamax or some other bone-strengthener along with the Femara. The Fosamax is good because it has vitamin D in it, which also helps to fight cancer. I read recently that Boniva is not considered a good choice for bc survivors, as it targets one part of the body (can't remember which now) over the whole.
I hate the SEs, but I'm very estrogen positive (90%), and Stage III, so for me, there's no debate about taking Femara. Yes, considering the alternative, I'll take joint pain!
I hope the Femara works for you! Good luck!
Amy G.
-
Amy,-
Boniva targets the spine as opposed to the hips. I had a conversation about a year ago voicing my concern--fact is -no matter what the ads say --none of the oral ones do a great job at the hips. For a 1% difference over a placebo I'd rather
have the convenience of a once a month pill and less esophageal problems but that has been my choice.
This is from
From medicalconumers.org
___________________________________
"The goal of osteoporosis drug therapy is not to stop bone loss or improve bone density. Rather it is to reduce the chance of having a serious fracture. Over the years, osteoporosis researchers have found that improving bone density does not always lead to fracture reduction. The drug class called bisphosphonates has dominated the osteoporosis drug market ever since Fosamax became available in 1994. Actonel, another bisphosphonate soon followed. Boniva is the latest drug in this class.
How good are these drugs at reducing the rate of hip fracture, the most serious consequence of osteoporosis? Not very. The first clinical trial proving Fosamax’s benefit showed that at three years,1% of the drug-treated women had had a hip fracture, compared with 2% of the women on the placebo.
Significantly, the elderly women in this trial all had evidence of a previous fracture; whereas many younger women are inappropriately put on long-term Fosamax purely because a bone-mineral density test showed bone loss. "
_________________________________________
Yearly Infusions of Zometa (Reclast), however, do work significantly against hip fractures and spinal fractures as has been shown in the Horizon Bisphosphonate trial.
How this once a year infusion would affect the chance of Osteonecrosis of the jaw, atrial fibrillation, and kidney toxicity is something that would have to be considered.
Amy---Also, for your knees you may want to try the Traumeel that Joan of Ardmore suggested---It does work --and works quickly! She got hers from WF. I got mine from iherb.com ---very good prices----you don't need to pay more for the gel ..Joan told me the ointment isn't sticky and its much cheaper.
Maryl---
I wouldn't give the switch a second thought. You've already probably had
worse hot flashes on Tamoxifen than you'll have on Femara. I felt they were more intense on Tamoxifen. You won't have as many foot and leg cramps.
Sleep--well that is another matter---but you can try melatonin (you need to stay with it for at least a week for it to work without weird dreams), or moon drops works great with a pleasant relaxing vanilla taste (thats available from Whole Foods and is a homeopatic lozenge )
I'm not big on Ambien CR (didn't work for me)or Lunesta (gave me metal mouth)and if you need more get a script for clonazopam (Klonopin). It will stop you from re-waking 2 hours after you finally fall asleep.
Musculoskeletal symptoms sometimes get better with time---and do not kick in overnight. Also, they tend not to be as bad in the under 50 crowd. ---Just us arthritic oldies who already have issues.
Don't think too much---you may do just fine! And you are not going to get every SE---I promise---and the ones you do get will vary in intensity---so my advise to you ---Don't anticipate. You'll do fine.
I've made it into year 5 and counting down----I know you will too!
Pam-
I can't help with the hair issues--I know some have talked of Biotin. Maybe one of the other gals will have some suggestions.
But, as to the spasms I can suggest Magnesium---I've been taking it for the past five years daily to help with the spasming from my Reflex Sympathetic Dystrophy----I can tell you --This is one supplement I would not be without---It does help. Also there are reports that vitamin D3 can help with pain. I've been taking 2000mg for the past year and I feel that is helping as well.
As I said above you may want to try the Traumeel ointment on the areas bothering you, --this has been way more successful for me than the countless other things I've tried. I won't bore you with that extensive list. LOL
Take care
-
Since you have gone through menopause, your onc is putting you on a post menopausal drug to block the natural estrogen your body produces. Femara is superior to tamoxifen if you are post menopausal. Side effects really shouldn't be anymore than what you experience on tamoxifen.
-
Thanks , that makes me feel so much better....I took the first one today.
-
Maryl-I have been on Femara since Feb. 07. I had an ooph. The SE's were pretty bad at first. I got carpal tunnel really bad and joint pain. My feet were numb a lot too. Fast forward to December and I must say the SE's are not so bad anymore. If I have to use stairs a lot my right knee hurts and getting up it takes a bit to get things moving. My hair is thinner on top than it was a few months ago. All and all it is liveable for me.
-
-
Thanks to you all again....
Categories
- All Categories
- 679 Advocacy and Fund-Raising
- 289 Advocacy
- 68 I've Donated to Breastcancer.org in honor of....
- Test
- 322 Walks, Runs and Fundraising Events for Breastcancer.org
- 5.6K Community Connections
- 282 Middle Age 40-60(ish) Years Old With Breast Cancer
- 53 Australians and New Zealanders Affected by Breast Cancer
- 208 Black Women or Men With Breast Cancer
- 684 Canadians Affected by Breast Cancer
- 1.5K Caring for Someone with Breast cancer
- 455 Caring for Someone with Stage IV or Mets
- 260 High Risk of Recurrence or Second Breast Cancer
- 22 International, Non-English Speakers With Breast Cancer
- 16 Latinas/Hispanics With Breast Cancer
- 189 LGBTQA+ With Breast Cancer
- 152 May Their Memory Live On
- 85 Member Matchup & Virtual Support Meetups
- 375 Members by Location
- 291 Older Than 60 Years Old With Breast Cancer
- 177 Singles With Breast Cancer
- 869 Young With Breast Cancer
- 50.4K Connecting With Others Who Have a Similar Diagnosis
- 204 Breast Cancer with Another Diagnosis or Comorbidity
- 4K DCIS (Ductal Carcinoma In Situ)
- 79 DCIS plus HER2-positive Microinvasion
- 529 Genetic Testing
- 2.2K HER2+ (Positive) Breast Cancer
- 1.5K IBC (Inflammatory Breast Cancer)
- 3.4K IDC (Invasive Ductal Carcinoma)
- 1.5K ILC (Invasive Lobular Carcinoma)
- 999 Just Diagnosed With a Recurrence or Metastasis
- 652 LCIS (Lobular Carcinoma In Situ)
- 193 Less Common Types of Breast Cancer
- 252 Male Breast Cancer
- 86 Mixed Type Breast Cancer
- 3.1K Not Diagnosed With a Recurrence or Metastases but Concerned
- 189 Palliative Therapy/Hospice Care
- 488 Second or Third Breast Cancer
- 1.2K Stage I Breast Cancer
- 313 Stage II Breast Cancer
- 3.8K Stage III Breast Cancer
- 2.5K Triple-Negative Breast Cancer
- 13.1K Day-to-Day Matters
- 132 All things COVID-19 or coronavirus
- 87 BCO Free-Cycle: Give or Trade Items Related to Breast Cancer
- 5.9K Clinical Trials, Research News, Podcasts, and Study Results
- 86 Coping with Holidays, Special Days and Anniversaries
- 828 Employment, Insurance, and Other Financial Issues
- 101 Family and Family Planning Matters
- Family Issues for Those Who Have Breast Cancer
- 26 Furry friends
- 1.8K Humor and Games
- 1.6K Mental Health: Because Cancer Doesn't Just Affect Your Breasts
- 706 Recipe Swap for Healthy Living
- 704 Recommend Your Resources
- 171 Sex & Relationship Matters
- 9 The Political Corner
- 874 Working on Your Fitness
- 4.5K Moving On & Finding Inspiration After Breast Cancer
- 394 Bonded by Breast Cancer
- 3.1K Life After Breast Cancer
- 806 Prayers and Spiritual Support
- 285 Who or What Inspires You?
- 28.7K Not Diagnosed But Concerned
- 1K Benign Breast Conditions
- 2.3K High Risk for Breast Cancer
- 18K Not Diagnosed But Worried
- 7.4K Waiting for Test Results
- 603 Site News and Announcements
- 560 Comments, Suggestions, Feature Requests
- 39 Mod Announcements, Breastcancer.org News, Blog Entries, Podcasts
- 4 Survey, Interview and Participant Requests: Need your Help!
- 61.9K Tests, Treatments & Side Effects
- 586 Alternative Medicine
- 255 Bone Health and Bone Loss
- 11.4K Breast Reconstruction
- 7.9K Chemotherapy - Before, During, and After
- 2.7K Complementary and Holistic Medicine and Treatment
- 775 Diagnosed and Waiting for Test Results
- 7.8K Hormonal Therapy - Before, During, and After
- 50 Immunotherapy - Before, During, and After
- 7.4K Just Diagnosed
- 1.4K Living Without Reconstruction After a Mastectomy
- 5.2K Lymphedema
- 3.6K Managing Side Effects of Breast Cancer and Its Treatment
- 591 Pain
- 3.9K Radiation Therapy - Before, During, and After
- 8.4K Surgery - Before, During, and After
- 109 Welcome to Breastcancer.org
- 98 Acknowledging and honoring our Community
- 11 Info & Resources for New Patients & Members From the Team