effect of hormone therapy on facial skin/wrinkles

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With hormone therapy in the not very distant future, it is making me wonder about the impact of AI's on facial skin and development of wrinkles. Vain, maybe, but...

All the side effects I keep reading about is comments on muscle, bone, joint pain, dry eyes, dry down below, and women feeling 30 years older. But are there changes to our skin? More Oily, less oily, change in texture, pore visibility, wrinkle development? Have you had to change your skin care regime?

Searching the web has not brought me any results so I am hoping you ladies can tell me if there is any impact, or if this is the one area of our body that might survive this relatively unscathed.

thank you and I wish everyone the best in this journey.

Comments

  • flashlight
    flashlight Member Posts: 698
    edited October 2020

    arabiansrock, It depends on what hormone therapy you are on. As we age menopause with the decrease in estrogen ages your skin, but hereditary plays a part on how much. If you take an aromatase inhibitor its goal is to remove all estrogen. My skin has improved on Tamoxifen even though I'm postmenopausal.

  • arabiansrock
    arabiansrock Member Posts: 98
    edited October 2020

    Flashlight, glad to hear that your skin improved! At least we get the occasional silver lining with all this! I would love to have less oil on my face and much smaller pores. But I don't want wrinkles, i don't think hubby would ever spring for a face lift, lol.

  • beach2beach
    beach2beach Member Posts: 996
    edited October 2020

    Wish I could say something positive. I'm on tamoxifen and because it causes so much dryness for me I've noticed more wrinkles on my upper lip. Feel like I can't keep up keeping hydrated. I use cream every day as my skin flakes.

    Stay hydrated as best as you can!

  • trinigirl50
    trinigirl50 Member Posts: 343
    edited October 2020

    Sorry to be the bearer of bad news but if you do go on an AI, chances are your skin will become very thin and dry. I used to look 12 years younger than my actual age, no wrinkles, oily to normal skin. Now my skin is paper thin and I have wrinkles around my mouth (I have never smoked) and I look older than my age. It was a slow process, but after 5 years of AI, I have 65+year old skin. I am 55. I do know that other women don't seem to be that affected, maybe you will be lucky. Also my hair got very thin but that seems to have stabilized for now. Good luck.

  • LillyIsHere
    LillyIsHere Member Posts: 830
    edited October 2020

    Trinigirl, my plastic surgeon told me the same when I asked him his thoughts on AI. He said the skin will get very thin and so the hair. Estrogen is the youth hormone and killing it... you get the idea. My skin has changed so fast, turned thin. Not much wrinkles yet but very thin and dry. I do use homemade masks to keep up with the changes.

  • WC3
    WC3 Member Posts: 1,540
    edited October 2020

    arabiansrock:

    Tamoxifen has had a positive effect on my skin. Also my hair has reverted back to it's 16 year old state; greasy even after washing.

  • arabiansrock
    arabiansrock Member Posts: 98
    edited October 2020

    ok so 2 people on Tamoxifen have had their skin get better, 3 ladies on AI's had their skin and hair basically turned dry and thin. I wonder if the skin improves again when we are done with AI's? And since they both block estrogen why would Tamoxifen make skin better I wonder?


  • MikaMika
    MikaMika Member Posts: 342
    edited October 2020

    Tamoxifen doesn't block estrogen production. Moreover, this drug increases estrogen levels. With AI your estrogen level will be lower than menopausal women normally have. It's like a very deep menopause :(

  • Veeder14
    Veeder14 Member Posts: 880
    edited October 2020

    Hi all,

    My MO said that Tamoxifen blocks estrogen to breast tissue only. It stillgives estrogen to other body parts. It sure gave estrogen to my uterus where a very thick lining formed.

  • LeesaD
    LeesaD Member Posts: 383
    edited October 2020
    I’ve been on AI’s (anastrozole) for three years. I was a young looking 49 when I started and now at 52, I look like I’ve aged 10 years. I look at photos of myself when I was first dx and even when I was bald from chemo and my skin on my face was full and healthy looking. Now it has lost its luster. I loved my hair also. I had such thick hair and after it grew back it has progressively gotten thinner. I was not in menopause when I was dx and was getting regulars periods. I had my last period my first day of first chemo treatment and then after chemo, I did Zoladex injections to suppress ovaries so I could go right to AI’s & skip tamoxifen and then had ovaries removed a few months later. The being thrown into menopause and the AI have definitely aged my skin and hair. I just hope that because I can ‘see’ the effects of the lack of estrogen that the meds are doing their job where they need to and there’s not enough estrogen left to feed any lingering pesky cancer cells as my cells apparently really liked estrogen. I am sad I look older. I don’t think it’s vain at all to be concerned about it and it’s a very valid concern.
  • arabiansrock
    arabiansrock Member Posts: 98
    edited October 2020

    Leesa did the MO explain how you got such a great OncoType score with stage IIb and spread to lymph nodes? That seems really unusual to me, although of course I am a newbie at this so.... I am sorry to hear the effect the AI's are having on your skin, but hopefully you will never have a recurrance and it will be worth it! It sounds like you have been through a lot.

    I am not pretty nor do I have "good" skin, i have a bunch of acne scars and large pores, and am now getting weird skin tag type things on my face, so its not that I am worried about not being pretty, its more that I am worried about being even uglier. And my hair and eyes have always been strong points so now I will lose my hair too, thin and dull. Lovely. Since I am already in menopause I wonder if I will thin less because I have already thinned quite a bit from menopause? One can always hope.

    If you are getting the feeling I am not in a good place right now, you would be right. Just when I was finally at a place in my life where I could find a little bit of happiness here and there, BAM, cancer takes it away. I am both sad and angry and start crying and screaming at my family with very little provocation. And yes am on Effexor and seeing a psych. Sorry, I'm just feeling whiney today.

  • dtad
    dtad Member Posts: 2,323
    edited October 2020

    We absolutely need estrogen for all vital organs including heart, bones, brain, bladder, hair and skin!

  • flashlight
    flashlight Member Posts: 698
    edited October 2020

    arabiansrock, I know you are not ugly!!! Please don't be so hard on yourself. Whine as much as you like or need to....we all do. My husband went to the dermatologist for those facial bumps and there is a cream for those. I can't remember the medical name. There is a newer retinol/vitamin A serum by prescription. I know I had just retired when I was diagnosed. Sending best wishes your way.

  • WC3
    WC3 Member Posts: 1,540
    edited October 2020

    My mother was a religious Retin A user until these past few years but I develop post inflammatory hyperpigmentation from it.

    Other than that, I've generally had good skin but my hair is fine and thin and splits and breaks easily. When I developed hypothyroidism, one of the most visible signs was my hair became dull as in completely lost it's shine. I found V05 hot oil to temporarily remedy this. My mother swears by Argan oil for hair though.

  • LillyIsHere
    LillyIsHere Member Posts: 830
    edited October 2020

    Thank you WC3. I am a retin A user for several years now. I just can't find a good natural moisturizer for daytime and my friend told me she loves argan oil for her face. I didn't know can be used for hair too.

  • ruthbru
    ruthbru Member Posts: 57,235
    edited October 2020

    I was on Arimidex 5 years with no bad effects to my skin (or hair either). Stay hydrated, use a very good moisturizer, good makeup, good sunscreen, and exercise. Exercise will keep the blood moving and give your skin a youthful glow (as well as giving your body that youthful, toned look). I would say that I look AND feel many years younger than my actual age (which is 67).

  • arabiansrock
    arabiansrock Member Posts: 98
    edited October 2020

    Ruth that is wonderful that you were able to actually feel better on AI's. Keeping hydrated (very difficult for me, I do not have a high thirst drive) and maintain exercise is wonderful advice for all of us. If I could grant wishes, it would be that all of us who have to take these drugs have as successful a treatment course as you did. It does give hope that we won't all have horrible side effects. May you stay cancer free and enjoy your good health, you have worked hard for it!

  • Mountainlover
    Mountainlover Member Posts: 89
    edited October 2020

    thank you Ruthbru, indeed, that gives hope. I am now spending considerable amounts of time to moisturise / hydrate every conceivable part of my body , hope it pays off in the medium term. I'm seeing deflated skin and awful hair now after just a few months of Femara , but that could also be from the stress of surgery , and of the diagnosis itself. Plus I stopped HRT overnight in early June, so my body has had a lot to adjust to I guess. Hopefully the changes from now on will be slower.

    All the best to all of you!

  • dtad
    dtad Member Posts: 2,323
    edited October 2020

    LillyIsHere...try hyaluronic acid as a moisturizer. Just make sure you get one that is 100 percent hyaluronic acid. Good luck!

  • dtad
    dtad Member Posts: 2,323
    edited October 2020

    flashlight...do you have more information on the newer prescription retina A? I've been using retin A for 30 years but would love to know about the newer version. Thanks so much!

  • dtad
    dtad Member Posts: 2,323
    edited October 2020

    is it Altreno?

  • ruthbru
    ruthbru Member Posts: 57,235
    edited October 2020

    Mountain, it is absolutely a combined effect of everything your body has been through! Stress alone can wreak havoc on the body. I had been on HRT too (and had chemo).....so yikes, I know how you're feeling! It took my body about a year after 'active treatment' to feel 'normal'.......so it takes time to process, both physically and mentally, what you have been through. An interesting note about hair, my beautician told me that your hair takes 6 months to bounce back after anesthesia! (I've had a couple, non-cancer related, surgeries in the past ten years. After learning that, I make sure I get my hair colored before the surgery so it will 'stick'.) There is a fun thread on the fitness forum called, "Lets Post Our Daily Exercise" if you want some fitness buddies. I really attribute exercise to be the KEY to getting back to feeling and looking good.

  • Mountainlover
    Mountainlover Member Posts: 89
    edited October 2020

    Ruthbru, that's great advise, I have slowed down on physical activity for the last week or so, the cool weather makes me want to hibernate but that doesn't help any of my SE , mood included!

    On the anesthesia- Yes, that sounds right. I recall my grandmother blaming anesthesia for her hair loss when I was little! Wish I didn't have 2 more general anesthesias planned for recon alone, but hey, this too will pass I guess.

    Have a great day!

  • LillyIsHere
    LillyIsHere Member Posts: 830
    edited October 2020

    Thank you dtad. Any good brand you recommend with 100% hyaluronic acid?

  • dtad
    dtad Member Posts: 2,323
    edited October 2020

    The Ordinary is a good inexpensive choice...

  • LillyIsHere
    LillyIsHere Member Posts: 830
    edited October 2020

    dtad thank you! I didn't know there was a product so cheap :). I have used a yoghurt and honey, some for eating and the left over for face :)

    FACIAL MASK WITH YOGURT AND HONEY | by UpMedik ( Your place to discover wellness ) | Medium

  • MicheleH57
    MicheleH57 Member Posts: 23
    edited November 2020

    And *AFTER* AI is completed? I am set for a 5-year course. Does the skin and hair "bounce back" after the course is completed? Or? Thx.

  • bravepoint
    bravepoint Member Posts: 404
    edited November 2020

    I've been on an AI for 3 years. My hair grew back as thick as it was before chemo and it's now curly. I opted not to colour it so it's grey. With COVID, most people are goingback to their natural colour so I fit right in. My skin is a bit dry but not too bad. I try to exercise and hydrate. Herbal tea is my go to since I can't seem to drink much water.

  • dtad
    dtad Member Posts: 2,323
    edited November 2020

    Hi everyone. IMO once you have been on an aromatase inhibitor for 5 years or more your estrogen supply is pretty much shot! Good skin care and health is your best bet. Good luck to all

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