Bi rads 4 c
Comments
-
Thank you so much for that information. We're hoping I still have swelling from the initial biopsy. If it gets any bigger, I'd be in stage 3. No chemo is needed unless I were to do lumpectomy or if I were HER2 positive but I am negative. They said they could always start me on tamoxifen of surgery gets delayed. I'm still very nervous about a lot of things. No lymph node involvement that they can see so far. But will check the nodes during surgery. I just thought I'd be able to have surgery sooner than later.
-
Ampmusic, whether or not chemo is recommended has nothing to do with the type of surgery - lumpectomy or mastectomy.
For those who are ER+ and HER2-, the criteria for chemo include the extent of nodal involvement (if any) and the aggressiveness of the cancer. At the extremes - very small non-aggressive tumor with no nodal involvement, or large aggressive tumor particularly if node positive - the pathology alone will determine whether or not chemo is recommended. In most cases however, the aggressiveness of the cancer is assessed by the Oncotype test (or similarly, the Mammaprint test), which evaluates the genetic make-up of the cancer cells (the Oncotype test looks at 21 genes within the cancer cell). If the cancer is found to be aggressive, chemo will be recommended regardless of whether the patient had a mastectomy or a lumpectomy.
Chemo is a systemic treatment; it's role is to track down and kill off any rogue cancer cells that might have escaped the breast (through the nodes or the bloodstream) and moved into the body. These rogue cells are what can develop into a metastatic (i.e. distant) recurrence. So chemo is given to reduce the risk of a metastatic recurrence. And because a metastatic recurrence happens outside of the breast, this risk is not reduced by having a mastectomy. That is why the type of surgery doesn't impact whether chemo is recommended. It's all based on the pathology and genetic make-up of the cancer.
Have you met with your Medical Oncologist yet? Surgeons only operate; it's the MO who looks at the whole picture and recommends the treatment plan. Was an Oncotype test done on your biopsy sample? If not, then it is premature for your doctor to tell you that chemo won't be recommended - there simply is not enough information available yet about your cancer to know what the most appropriate treatment plan will be. Sorry if that is disappointing.
-
An onco test has not been done yet. I'm assuming they'll do it when I have my surgery. The lump is sooooo big I'm sure the results will be high. I'm still scared out of my mind. I know chemo and or radiation isn't going to be determined yet until after my surgery. Oncologist and my whole team decided chemo wasn't needed before surgery despite the lump being as big as it is. Praying everything goes well.
-
Ampmusic14, your post caught my eye. I just wanted to weigh in and ditto the fact that large tumors are not necessarily aggressive. My BC had infiltrated over an entire quadrant of my breast, and every member of my care team really thought I would be getting chemo, to the point where my MO was already talking about clinical trials he wanted to put me in, before I had surgery or an oncotype score. After surgery, my score came back and chemo was off the table.
It is my understanding that chemo is sometimes done before surgery when they want to try to shrink the tumor down first (usually to do a lumpectomy instead of mastectomy). That might be what your doctor meant by no chemo being needed unless you had a lumpectomy. I remember my surgeon mentioning that possibility to me early on. Beesie is extremely knowledgeable and very correct in that there is really no way to know anything for sure about what your treatment plan will look like until after your surgery and oncotype are done. Whether or not chemo and/or radiation is recommended will take everything into account-your age, tumor size, aggressiveness, node involvement, etc.
I know that everyone tells you not to worry, and I also know that is impossible. Spending time with those you love and staying busy are good strategies. Personally, I was prepared for the worst, so I was surprised when it wasn't as bad as I thought it was going to be. So sorry you're going through this.
-
I may not have explained myself well enough in a prior post. I know there's still a chance I'll need chemo. But yes you're right, it wasn't needed before surgery because I'm having a mastectomy and not a lumpectomy. My oncologist said he'll over treat me vs under treat because I'm so young. I think my tumor was graded high which makes me so nervous... So I'm definitely planning for the worst and hoping for the best. I have a week yet before my surgery. I'm still scared for the future...
-
ampmusic - I'm assuming you aren't HER2 positive, or you WOULD be having chemo first. When you get a chance, go to 'my profile' and fill in the diagnosis & treatment plans to date so we can follow you more easily. Good luck with your surgery.
-
Correct, I am HER2 negative which is also why I didn't need to start with chemo. I'll see if I can figure out the profile thing. Thanks.
-
Well I had my surgery on Tuesday. I was not expecting to be as sore as I am. No sentinel node involvement and no involvement in the two nodes she took out just to check... But if I'm reading my pathology report correctly, it sounds like it is in the lymphatic system...?? But never made it to the nodes. So I don't know if that means it's microscopic in my blood. Have not been checked yet for oncotype but my navigator is reaching out to oncology about it. My grade went from a 2 to a 3 which has me very scared for the future and the tumor was 4.8cm like the mri said. More appointments next week, so I'll know more then.
-
AmpMusic - Glad there is no SN involvement. However if it were in the lymphatic system, it's likely your stage would be higher. Hang in there until you can talk to the oncology doc.
-
I'm confused. The nodes that are closest and get removed during surgery are the sentinel nodes, I thought? Why would a surgeon by-pass the sentinel nodes and take out others? And if it's not in your nodes, how can it be in the lymphatic system? I hope your surgeon clarifies everything.
-
Lymphovascular invasion, LVI?
LVI does not impact stage.
-
I know they tested the sentinel node and it was negative. I don't know if that is one of the two taken out...? I only know two nodes were taken out but all were negative. One part of the pathology said peritumoral lymphatic invasion is present. So that's the part I don't understand and is confusing. I'll see the surgeon in a few days and I know she'll explain it all to me. I also contacted my oncologist to see if I get an answer.
-
Peritumoral lymphatic invasion is the "L" part of LVI. It means that cancer cells have been found in the lymph channels around the tumor. These lymph channels are what take cancer cells up to the lymph nodes.
"Lymphovascular invasion (LVI) is defined as the presence of tumor cells within a definite endothelial-lined space (lymphatics or blood vessels) in the breast surrounding invasive carcinoma." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078671/ - The rest of the article is not relevant because it speaks to the presence of LVI after neoadjuvant chemo (pre-surgery chemo), but this was the best definition of LVI that I could. "Peritumoral" simply means "around a tumor".
As for the two nodes, for most of us, the SNB procedure results in more than one node being removed. When the dye and/or isotopes are injected into the breast prior to the surgery, they flow into the nodes. Any nodes that have dye or isotopes are removed. In some cases that's only one node but in other cases it's as many as 5 nodes or more. I think for most of us, it's 2 or 3 nodes. I had 3 removed during my SNB. Both of the nodes removed would be considered sentinel nodes.
-
Thank you very much. That's what I was thinking, but I'm no doctor so it can be very confusing. I'll know more of my treatment plan by this week and the end of the month.
-
Another update. I had my pathology report appointment today with my surgeon and everything went well. It was all good news. No lymph node involvement, clean margins. The rest of my treatment depends on my oncotype score which is pending. I'll see oncology at the end of the month. The one scary thing was just that the cancer was very aggressive!
-
Ampmusic - great news - no lymph involvement & clean margins. Woo Hoo.
-
Another contradiction - if it was "very aggressive" why is it grade 2 and not grade 3? It's like you are getting verbal explanations that don't match the pathology.
-
It changed to grade 3. I just need to change my profile thingy.
-
Keeping y'all updated. My oncotype score was high for my age putting risk of recurrence high as well. So I will be doing chemo. Waiting for the rest of that to pan out right now.
-
Sorry to hear that. I suspected that chemo would be part of your treatment plan, given your age and the size of your tumor. Hopefully chemo does it's job and brings your recurrence risk nice and low. Good luck with chemo!
-
Thank you! Port placement was last week and chemo starts at the end of the month. I'll be getting taxotere and cytoxan.
Categories
- All Categories
- 679 Advocacy and Fund-Raising
- 289 Advocacy
- 68 I've Donated to Breastcancer.org in honor of....
- Test
- 322 Walks, Runs and Fundraising Events for Breastcancer.org
- 5.6K Community Connections
- 282 Middle Age 40-60(ish) Years Old With Breast Cancer
- 53 Australians and New Zealanders Affected by Breast Cancer
- 208 Black Women or Men With Breast Cancer
- 684 Canadians Affected by Breast Cancer
- 1.5K Caring for Someone with Breast cancer
- 455 Caring for Someone with Stage IV or Mets
- 260 High Risk of Recurrence or Second Breast Cancer
- 22 International, Non-English Speakers With Breast Cancer
- 16 Latinas/Hispanics With Breast Cancer
- 189 LGBTQA+ With Breast Cancer
- 152 May Their Memory Live On
- 85 Member Matchup & Virtual Support Meetups
- 375 Members by Location
- 291 Older Than 60 Years Old With Breast Cancer
- 177 Singles With Breast Cancer
- 869 Young With Breast Cancer
- 50.4K Connecting With Others Who Have a Similar Diagnosis
- 204 Breast Cancer with Another Diagnosis or Comorbidity
- 4K DCIS (Ductal Carcinoma In Situ)
- 79 DCIS plus HER2-positive Microinvasion
- 529 Genetic Testing
- 2.2K HER2+ (Positive) Breast Cancer
- 1.5K IBC (Inflammatory Breast Cancer)
- 3.4K IDC (Invasive Ductal Carcinoma)
- 1.5K ILC (Invasive Lobular Carcinoma)
- 999 Just Diagnosed With a Recurrence or Metastasis
- 652 LCIS (Lobular Carcinoma In Situ)
- 193 Less Common Types of Breast Cancer
- 252 Male Breast Cancer
- 86 Mixed Type Breast Cancer
- 3.1K Not Diagnosed With a Recurrence or Metastases but Concerned
- 189 Palliative Therapy/Hospice Care
- 488 Second or Third Breast Cancer
- 1.2K Stage I Breast Cancer
- 313 Stage II Breast Cancer
- 3.8K Stage III Breast Cancer
- 2.5K Triple-Negative Breast Cancer
- 13.1K Day-to-Day Matters
- 132 All things COVID-19 or coronavirus
- 87 BCO Free-Cycle: Give or Trade Items Related to Breast Cancer
- 5.9K Clinical Trials, Research News, Podcasts, and Study Results
- 86 Coping with Holidays, Special Days and Anniversaries
- 828 Employment, Insurance, and Other Financial Issues
- 101 Family and Family Planning Matters
- Family Issues for Those Who Have Breast Cancer
- 26 Furry friends
- 1.8K Humor and Games
- 1.6K Mental Health: Because Cancer Doesn't Just Affect Your Breasts
- 706 Recipe Swap for Healthy Living
- 704 Recommend Your Resources
- 171 Sex & Relationship Matters
- 9 The Political Corner
- 874 Working on Your Fitness
- 4.5K Moving On & Finding Inspiration After Breast Cancer
- 394 Bonded by Breast Cancer
- 3.1K Life After Breast Cancer
- 806 Prayers and Spiritual Support
- 285 Who or What Inspires You?
- 28.7K Not Diagnosed But Concerned
- 1K Benign Breast Conditions
- 2.3K High Risk for Breast Cancer
- 18K Not Diagnosed But Worried
- 7.4K Waiting for Test Results
- 603 Site News and Announcements
- 560 Comments, Suggestions, Feature Requests
- 39 Mod Announcements, Breastcancer.org News, Blog Entries, Podcasts
- 4 Survey, Interview and Participant Requests: Need your Help!
- 61.9K Tests, Treatments & Side Effects
- 586 Alternative Medicine
- 255 Bone Health and Bone Loss
- 11.4K Breast Reconstruction
- 7.9K Chemotherapy - Before, During, and After
- 2.7K Complementary and Holistic Medicine and Treatment
- 775 Diagnosed and Waiting for Test Results
- 7.8K Hormonal Therapy - Before, During, and After
- 50 Immunotherapy - Before, During, and After
- 7.4K Just Diagnosed
- 1.4K Living Without Reconstruction After a Mastectomy
- 5.2K Lymphedema
- 3.6K Managing Side Effects of Breast Cancer and Its Treatment
- 591 Pain
- 3.9K Radiation Therapy - Before, During, and After
- 8.4K Surgery - Before, During, and After
- 109 Welcome to Breastcancer.org
- 98 Acknowledging and honoring our Community
- 11 Info & Resources for New Patients & Members From the Team