Interpreting test results
I am 37 and had sudden pain in my right breast and was referred to my first mammogram and ultrasound. Funnily enough, the right sounds to be okay, but they found calcifications and some other terms I don't quite understand in the left. I have an MRI on Tuesday and am very nervous. Can anyone help me understand this? Thanks!!
MRI:
Breast density: B: scattered areas of fibroglandular density
Findings: No dominant mass, architectural distortion, asymmetry, or suspicious calcification is seen working the symptomatic right breast
in the contractural, asymptomatic left breast, there is a linear, lobular, somewhat beaded appearing density at approximately the 3:00-4:00 regional the left breast which has a suggested focus of architectural distortion at the posterior extent
ultrasound of the symptomatic right breast demonstrates at 6:00, 6cm from nipple a 6x5x2mm hypoechoic nodule with suggested internal punctate hyperechoic foci, possibly punctate calcifications. In the retroareolar region there are mildly dilated ducts which measure up to 4mm in diameter without intraluminal adnormality.
Ultrasound of the contra lateral, asymptomatic left breast demonstrate at 4:00-5:00, 5cm from nipple a 9x6x3mm hypoechoic nodule with internal hyperechoic foci, probable calcifications which is similar in appearance to the right breast.
At 3:00-4:00, 5cm from nipple there is a 1.1x0.6x0.3cm linear hypoechoic focus wither internal hyperechoic foci, probable calcifications this finding is in the vicinity of the mammographic finding though significantly smaller.
Conclusion:
1. No mammographic or sonography abnormality to correlate with right breast pain
2. Left breast 3:00-4:00 region linear density with suggested posterior associated architectural distortion mammographicly, 1.1cm hypoechoic linear structure with associated calcifications sonographically which correlated in location though is much smaller in size
3. Recommend further evaluation with breast MRI.
BI-RADS 0: incomplete: need additional imaging evaluation and/or prior mammograms for comparison
Comments
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There is not enough pertinent information to make a call on these findings. The report is incomplete in that it does not mention the margins of the masses, whether or not there is posterior shadowing, nor does it mention if there is internal blood flow. These are three things that I personally use to make a decision. The fact that they are not mentioned makes one believe these findings may not be present. I also assume there are autocorrect errors in the transcribing of the report to this post. I think it's odd that the suspected calcifications were seen on US and not mentioned in the mammogram portion of the report.
Most of the time a mass with internal calcifications is either cancer or a fibroadenoma. There are no terms in the report above that are routinely applied to cancers. One would assume if it looked like a cancer the Birads woud not have been 4a which leans toward it more likely being benign. Also it is less likely to have identical bilateral findings of cancer than it is to have multiple fibroadenomas which is much more common.
The fact that you are having an MRI soon makes my opinion more for reassurance than for clinical decision making and since I had to infer most of my "conclusions", I may be wrong, so let us know what the MRI shows.
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Thank you so much for taking the time to look at this! I very much appreciate it and will keep you posted.
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Hi Djmammo,
Hoping you could help me out again. I had an MRI completed and below are the results. My dr has given me an order for an ultrasound guided biopsy, but I’m fairly certain she did not read the entire report. They found increased uptake at the 8:00 position, but the MRI and US found calcifications in the 3-4:00 position. I’m not sure what I’m supposed to do at this point and I’m not confident in my GP. Even the MRI location isn’t consistent as under assessments, it says 7:00.Any thoughts?MRI Bilateral Breasts With and without Contrast
History: Left breast density
Technique: 1.2mm axial sections were obtained with 3D T1 techniques. 4mm sagittal sections were obtained with T2 fat suppressed techniques. 4mm axial sections were obtained with STIR techniques. 1.5mm axial sections were obtained with T1 3D techniques before and after the administration of 20cc of ProHance injected through the right arm. Five sequences were obtained at 1 minute intervals after the injection of contrast. Subtraction sequences were generated.
Comparison: the report of the patient's mammogram of 12/12/19 and the ultrasound study of 12/12/19 have been reviewed.
Findings: no lesions are seen in the included portions of the upper abdomen. The included portions of the lower chest have a normal appearance.
At the 8:00 position of the left breast, there is a 7mm focal area of increased uptake with contrast material. This is of some concern.
There are no other areas of increased uptake identified.
This area of increased uptake is not the location described on the prior studies. Still, correlation with all of these studies should be helpful in further assessment.
Assessment: Suspicious, ACR BIRADS category 4. There is an area of suspiciously increased uptake at 7:00 in the left breast.
Recommendations: I would suggest correlation with the mammogram and ultrasound studies, and the decision on biopsy should be based on all of the findings, if there is a suspicious area on the mammogram and ultrasound study, then biopsy can be guided based on those findings.
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The MRI report leaves out the kinetics curve of the enhancement, a description of margins and never actually uses the term "mass" so I am really not sure what to make of it.
What often happens is a biopsy will be done by one method or the other, a marker is placed and images are taken with the other modality to see if the findings in question match up. This will also help to tell if the calcs and the mass are separate or not.
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Opinion
In light of the terms used in the report and the contents of the recommendation my question is how often does this particular radiologist read breast imaging? They were willing to issue a report without comparing them to the actual prior studies and in addition implies someone else should do that comparison. I'm not sure that I could determine that the locations don't match working only from reports. I don't mean to disparage anyone but the terms used are not what you would expect from someone who specializes in breast imaging.
The prior images and this MRI need to be compared in order to come to a reasonable conclusion with a reasonable recommendation prior to biopsy.
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I appreciate your candidness. I have the same concerns. I too felt the report was lacking and I am not in the medical field. I was also wondering who is supposed to compare the reports, if they did not. Based upon this persons signature, they should be qualified, but I wonder and have wondered this entire process if the holidays are literally getting in the way. My first thought is to call this person and see if I can have them clear this up. Or are there specialists out there that can do this?
Thank you for your time, especially today being a holiday. Happy new year. -
Yes, there are services, like this one I chose randomly as an example: https://argusrad.com/our-solutions/over-reads/ Google will help. Make sure they take cases from patients and not just doctors. You could also contact a nearby university hospital who may help. Make sure you have copies of all your imaging before contacting them.
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Hi DJMammo,
You have been so helpful and I truly appreciate it. I have since received a 2nd opinion and another ultrasound of the spot in my left breast. I will be having a biopsy in the next couple of weeks, but was curious to know your opinion of the new report. Again, I can’t thank you enough for all you do. If it weren’t for you, I would be really struggling to navigate this.ULTRASOUND FINDINGS:
High-resolution real-time ultrasound scanning was performed.
Ultrasound was performed to evaluate an outside ultrasound finding in the left breast at 3 o'clock 5 cmfn seen on 12/12/19. Today, there is a hypoechoic mass with angular margins in the left breast at 3 o'clock located 5 centimeters from the nipple. This may represent an intraductal process. No internal vascularity is seen.
IMPRESSION:
Hypoechoic mass in the left breast at 3 o'clock 5 cmfn, possibly intraductal, is suspicious. An ultrasound guided biopsy is recommended.
BI-RADS Category 4B: Suspicious Abnormality
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Reviewing the above briefly it seems like there are 2 things on the left, one at 3 and one at 8. Will they be biopsying both of these?
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I should have included all the information! Sorry. the 2nd opinion included a review of the MRI and they were not able to find something at 8:00, but perhaps at 6:00. They would like to redo the MRI, but that is on hold while I work with insurance. Here is the report on the 2nd opinion of the imaging.
01/09/2020 Addendum:
ULTRASOUND FINDINGS:
Upon further review, a repeat targeted ultrasound of the LEFT breast is recommended to further characterize the elongated hypoechoic lesion labeled at LEFT breast 3- 4 o'clock 5 cm from nipple on outside ultrasound to
exclude an intraductal mass. The recommendation for repeat breast MRI, as noted below, remains unchanged.
BI-RADS Category 0: Incomplete: Needs Additional Imaging Evaluation
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HISTORY:
Patient is 37 years old and is seen for an abnormal finding on a prior study.
EXAMS INTERPRETED:
Bilateral mammogram with tomosynthesis 12/12/2019 Ultrasound bilateral breast 12/12/2019
Breast MRI 12/27/2019 (limited review)
MAMMOGRAM FINDINGS:
Films from outside facilities demonstrated the findings noted below.
There are scattered areas of fibroglandular density.
There are multiple subcentimeter circumscribed oval masses in both breasts. Their multiplicity and bilaterality suggest a benign etiology, such as
cysts among other benign etiologies. A few scattered similar-appearing small groups of punctate calcifications are also noted in both breasts,
most likely of benign etiology. No suspicious masses, suspicious calcifications, or other abnormalities are appreciated in either breast.
ULTRASOUND FINDINGS:
Submitted ultrasound images from both breasts depict the following: --right breast 6:00, 6 cm FN, a circumscribed oval hypoechoic mass with possible calcifications measured at 6 mm (images 4- 11)
--right breast retroareolar, mild duct ectasia (images 14- 16)
--left breast 4:00- 5:00, 5 cm FN, a circumscribed oval hypoechoic mass
with possible calcification measured at 9 mm (images 17- 24)
--left breast 3:00- 4:00, 5 cm FN, mildly ectatic duct and a portion of the
duct with intraluminal debris versus an adjacent complicated cyst measured at12mmx3mm(images25-38)
The above depicted findings do not demonstrate suspicious sonographic features.
NOTE: Breast MRI was performed at outside facility on 12/27/2019. The written report from that exam stated, "at the 8 o'clock position of the
left breast, there is a 7 mm focal area of increased uptake with contrast material. This is of some concern." No distance from the nipple, image number, or key image given. Upon limited review of the submitted MR images, there are similar-appearing foci of enhancement scattered throughout both breasts, but with a predominance in the lateral region of the right breast. I cannot definitively identify the enhancing focus of concern in the left breast at 8 o'clock described on the outside report. A possible corresponding enhancing focus is seen on image 24/104 of series 8; however, this focus is at the approximate left 6 o'clock position and does not appear unique from the other enhancing foci in either breast.
IMPRESSION:
No mammographic or sonographic evidence of malignancy in either breast.
Patient underwent breast MRI at outside facility on 12/27/2019. The written report from that exam described a 7 mm enhancing focus of concern in the left breast at 8 o'clock. I cannot definitively identify that focus on my limited review of the submitted images, as detailed above. Given this, repeat breast MRI is recommended at this time. If this is not feasible,
then a 6-month follow-up breast MRI should be performed.
BI-RADS Category 2: Benign Finding(s)
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Good.They dont think its a cancer. Let us know how the biopsy goes.
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djmammo,
Are you willing to help others with difficult radiology situations under this topic? My family has a significant history of breast cancer. My mother and her sister have both had two incidents of breast cancer, and I have had breast cancer. My sister had a small 2mm spot on her left breast. It was being monitored over the last year. A mammogram in Dec 2019 revealed changes in the mass. A needle biopsy was ordered and performed. 4-6 samples were taken from the breast. The radiology report came back inconclusive. The radiologist thinks the sample was contaminated in the course of the testing. The very small amount of cancer cells showed strong similarity to the previous sample under assessment. And there was primarily healthy breast tissue in the sample.
The radiologist apologized and offered to do an MRI to help provide more clarity. My sister was referred to a breast surgeon for an opinion and was told that she needs to have a lumpectomy and removal of several lymph nodes to ensure the problem is addressed. Having been through all of this myself I doubt any determinative diagnostic information would be gleaned from an MRI at this point. On the other hand surgery including removal of lymph nodes seems too aggressive. What are your thoughts?
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I can help interpret reports for you here but these kinds of decisions cannot be addressed in this forum.
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TallnTerrific, another option for your sister would be a small excisional (surgical biopsy) to remove the entire suspicious area. That's usually the next step when the results of a needle biopsy are unclear - I've had that as have many others on this site. If the surgical biopsy finds nothing, you sister is good to go. And if the biopsy finds cancer, then she can go back for the lumpectomy (to ensure clear margins) plus node removal. Do you know if there was a reason why this wasn't suggested by the surgeon?
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Another member sent me to this thread.
In 2018 I had my first mammogram. 2D. Dense tissue to 2D from here on out.
In 2019 I had a 3D mammogram that found a focal asymmetry in "far posterior lateral left breast seen on exaggerated lateral cc view". Went for diagnostic mammogram and it was normal tissue folded upon itself.
Just had my 2020 3D mammogram Thursday and they found “indeterminate asymmetry in central posterior left breast on cc view only". Got called back but haven't schedule appt yet (just found online results today).
I can't find anything online about "indeterminate" asymmetry. What does this term mean?
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Bessie, their is a reason he wanted to do lymph nodes at the same time. My sister has a blood clotting disorder and is on Coumadin. The surgeon thinks that it would not be safe to wait to find out about whether there is cancer and go back for a second surgery to remove lymph nodes. I guess I understand but it seems crazy
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Hi DJMammo,
I had my core biopsy yesterday and received a report that said “As the mass significantly collapsed following the first pass, differential considerations would include portion of a distended duct and complicated cyst.“ They made no mention of this to me, but I feel it sounds like good news. Am I correct in this assumption?
Thank you, -
Any report that does not use the word "cancer" is an encouraging one. There should be a section in a report for recommendations, what does it say? I assume they will ask for follow up imaging in a few months.
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It did not include anything else as the results have not come in. This was a report of just the biopsy itself.
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That's a bit different. This post bx report explains that there was a cystic component to the target but that's not a definite sign of it being benign. Wait for the path report for a better answer.
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I appreciate your help! My results were benign!
Final Diagnosis
A. LEFT BREAST, MASS AT 3:00 5 CMFN, CORE BIOPSY:
- Benign breast parenchyma with apocrine cysts and associated papillary apocrine metaplasia.
Histology is concordant with imaging findings.
Recommendations:
1. No further follow-up is necessary for this site of biopsy in the left breast at 3 o'clock 5 cm FN; site denoted by a hydromark coil clip.
2. Patient requires follow-up breast MRI, as noted on rad interp report dated 1/8/2020. Please refer to that report.
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I had a lumpectomy of my less than a centimeter tumor and then 9 days later more margins cut out. I just had a full mammogram. So this would be breast mammogram 450 it seems like - but my results from this one say I have LOW density. I have always been very dense. As in all 449 other exams over decades state they are very dense, not just dense. There is no way this recent mammogram result is mine thenis it?
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