Confused About Pathology Report

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Margot62
Margot62 Member Posts: 31
edited March 2019 in Just Diagnosed

Hello All,

I'm sorry we are all in the same boat and I thank you in advance for any information you can offer. I don't understand my pathology report and the books I bought aren't very helpful either. I'm hoping someone can shine a little light!

Here's my diagnosis:

*Invasive Ductal Carcinoma Grade 2

*DCIS Solid and Cribriform Patterns Grade 2

So, does this mean the cancer in the duct spread into the tissue? I was told by the radiologist during the biopsy the tumor was only 4mm. Very tiny. I'm so confused about having two diagnosis in the report.

No staging was given. Is that because you aren't staged until after surgery? Or are grades and stages the same thing?

*I'm ER positive with a score of 8

*Im progesterone positive with a score of 6-7

*my K1-67 is 10-15%

*Her2 is still pending.

Is it great that the tumor is so tiny or is it more about what the tumor shows? Is this two-pronged diagnosis a truly bad thing?

Thanks for any help you can offer! I’m sorry I posted this twice

Comments

  • Meow13
    Meow13 Member Posts: 4,859
    edited March 2019

    Sounds like DCIS with some IDC, so yes it is invasive grade 2, and both er and pr positive. Doesn't sound too bad, do you know if 4mm is the invasive part?

  • blah333
    blah333 Member Posts: 270
    edited March 2019

    4mm is very small! But it sounds like you have DCIS + IDC which means you do have breast cancer that is outside of the ducts (in the breast tissue). They will be focusing on treating IDC, the more troubling diagnosis. Your report just means there were both cancerous cells found within the ducts and outside of them, in the breast tissue. It's likely you will next get an MRI, your doctor should soon be able to tell you your options. DCIS is Stage 0.... I am not entirely sure of all the other stages but once it is in the breast tissue that is Stage 1... however just because it is in the breast tissue does not mean it has reached your lymph nodes. The Grade is how different the cells appear from normal cells. It's usually 1-3. And Grade 3 means it is likely growing or developing faster or is more advanced, from what I understand. Hopefully you have another appointment soon where you can gather more information. From the information you've posted it sounds like Stage 1, however you really don't know until after surgery and they look at the removed tissue under microscope. Goodluck.!




  • Dee1987
    Dee1987 Member Posts: 22
    edited March 2019

    hi there can I join the confused club I was diagnosed back in november at 31yrs old with a 15mm idc (weakly er positive 15%) and to top it off I'm brca1 positive too!I was operated first and my nodes were negative and lvi absent but it says something about extensive necrosis? Anyone I've asked about necrosis on their pathology have said no. Then again generally these aggressive kind of cancers get chemo first then removed I opted the opposite :-

  • Salamandra
    Salamandra Member Posts: 1,444
    edited March 2019

    It is very common, I think much more common than not, to have DCIS alongside IDC. So don't worry about that.

    A small tumor is good, but the genetics of the tumor also matters a lot for treatment and somewhat for prognosis. Estrogen and progesterone receptor positive are both favorable. A lot of places don't even do Ki anymore, but you'll probably get a bite of your tumor sent for genomic testing (likely either Oncotype or Mammaprint) after it's removed. That will help guide decisions about chemotherapy and also give you more specific to you statistics about recurrence.

    Grades and stages are different. But it's normal not to have a stage on the pathology report because even initial clinical staging also depends on a doctor feeling your lymph nodes for palpable signs of possible lymph node involvement. For the final staging, that only comes post-surgery when they do the final pathology of the tumor. If you don't end up having neoadjuvant chemo (before surgery), you can look up your stage pretty easily though. Take heart, with such a small tumor and ER+/PR+, you can have multiple lymph nodes involved and still be stage I.

    You'll know more about it once they finish the Her2 testing. Nowadays, Her2 is either neutral or favorable for prognosis because of the new drugs they've got. If you are Her2 positive, make sure to ignore any older statistics that use data from more than about 5-10 years ago.

    It's a long haul and it's impossible to understand everything at the beginning. The picture will get more and more clear as you get more test results in, more doctors' explanations, and more knowledge. In many ways, you're at the most stressful part right now.

  • edwards750
    edwards750 Member Posts: 3,761
    edited March 2019

    It is very confusing because there are so many factors involved in a DX and with the medical jargon used you almost need a medical degree to understand what they mean.

    Salamandra’s post is an excellent analysis of BC and what to expect.

    I had a lumpectomy and when the Path report came back it showed a micromet in my SN. My BS was surprised- I was stunned. My MO ordered the Oncotype test and my score came back low. I too had a small tumor. That score allowed me to dodge chemo. I had IDC, Stage 1b, Grade 1.

    Once all your tests are done you will have a clearer picture of what surgeries and treatments will be recommended. It seems like a long wait but once those decisions are made the process should move quickly.

    Good for you doing your homework but it is definitely overwhelming to be sure. This website is a godsend. I signed on when I was DX in 2011. We all are here for the same thing in various stages and grades.

    I’m 7 years out last August so there is a light at the end of the tunnel.

    Keep the faith and keep us posted.

    Diane

  • Margot62
    Margot62 Member Posts: 31
    edited March 2019

    thank you, thank you for such a clear reply! I understand things much more, thanks to all of you. What a godsend this site is!

    During the sonogram when I was called back in for a suspicious mammogram, the radiologist looked at my lymph nodes and thought they looked clear. But I'm guessing the truth about cells migrating comes after a node or nodes are removed, correct?

    I think the 4mm tumor is the IDC, but I'm not certain. It sounds like the real evidence gathering comes now—an MRI, etc. When do you decide what kind of surgery you are going to have?

    Thankfully, I live down the street from the best cancer hospital in the country. I was sad when my husband was recently transferred to Houston, away from our friends and family on the East Coast, but now I see the blessing in it!

    Thank you to everyone who has replied!

  • santabarbarian
    santabarbarian Member Posts: 3,085
    edited March 2019

    Necrosis may indicate a high grade. Because high-grade cancer either grows or dies, it dies inside the tumor and the edges grow. My cancer was grade 3 and had a lot of necrosis according to path report.

  • Salamandra
    Salamandra Member Posts: 1,444
    edited March 2019

    I had necrosis but my cancer was staged grade 1 on the biopsy and grade 2 after pathology. I'm not sure exactly how the necrosis numbers work.

    The breast surgeon will advise you about options for surgery, likely after the MRI results are in. If the MRI doesn't show any other areas of concern, they're more likely to recommend lumpectomy. If the MRI shows multiple other areas of concern, they may want to do more biopsies first or recommend a mastectomy if they need to take out enough areas that a lumpectomy would have poor cosmetic results, or depending on the location of the areas.

    Yes, like knowing the final size and grade/hormones of a tumor has to wait for pathology, same for knowing for certain on the status of lymph nodes. A person can have palpable lymph nodes that turn out not to be cancer, or there can be cancerous lymph nodes that are not palpable. If they haven't identified suspicious lymph nodes, you will probably have a sentinel lymph node biopsy, where they try to identify the first couple of lymph does that cancer from your breast would drain towards, remove just those (might be as few as 1 or as many as 7+, depending on your anatomy), and do an extensive pathology. They usually do that at the same time as the lumpectomy or mastectomy. If those come back clear, they assume there is no lymph node involvement (there are false negatives, but the rate is very low).

    I agree that this site has been so helpful. I also had a silver lining, not too long before my diagnosis, I had changed to a job with excellent health insurance and FMLA protections. The job has had its ups and downs but wow was I glad about the change once I got my diagnosis!

    Living a few blocks from the cancer center will make life much more convenient! I'm kind of jealous, and I wasn't so far myself!

  • 239Happy
    239Happy Member Posts: 6
    edited March 2019

    Salamandra thank you for sharing your knowledge. I'm apparently the IDC, my doctor said I need lumpectomy and radiation treatment. She said I'm Stage 1. All my other tests came back positive for the lymph nodes and protein receptors. I do want a 2nd opinion, mainly because I want a better hospital.

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