Afimito/ aromasin

janice54. I don't have any to tell you. I've

Been. On AA for 3weeks and 3 days. I don't have mouth sores, that's good. The weight loss and patin have been horrible.

Janice- I think Grannax meant "pain". For Grannax and myself, the weight loss began immediately. I am down 25 pounds since the end of October and I'm not sure exactly how much Grannax has lost but it is significant. I have had the mouth sores and was taken off Affinitor for 9 days. During that time they completely went away. I restarted Affinitor this past Sunday night so we'll see how it goes. From my perspective, the sores and loss of appetite are the worst!

Onc gave me an appetite stimulate (derived from marijuana) and it made me high as a kite. Going to request a lower dose when I see her next week.

I'm sure there have to be some good stories out there about Affinitor, but I can't seem to find them. Also, I started using Biotene toothpaste when my sores and tongue got raw....there was no other toothpaste that I could use. I will keep you updated on how things progress. And...by the way, I also go to Duke Cancer Center!

I'm wishing you the very best as you make these decisions...

MM (Angie)

My eating is better, found out I do like glucerna rich chocolate shake, Milk tastes good and lemon drop candy helps with the bad taste in my mouth. Still having pain especially bad at night. Still needing lots of sleep.

Janice, if you don't want to take A/A you certainly don't have to. You could try Xeloda instead.

But. Not everyone has every side-effect. I thought the first three months of A/A were easy. Then it got harder. I also thought Xeloda was relatively easy but other women have a really hard time with it.

You could make a trial of the drug and if you don't like it, move on to something else. You don't need to 'suffer'.

Hi Janice, I am still in early days of A/A. Starting 3rd month of Aromasin and 2nd of Afinitor. I have had minor se's, but nothing horrible. I am pretty active and find I do get very tired at times, but have been able to bounce back after a rest. I have not lost a pound and have only had a couple of minor mouth sores. No D or changes in taste for me so far. I won't have scans until March, so don't know if it's working, but tumor markers seem to have stabilized since starting this combo.

I'm very sorry for those who are having or had a tough time on this tx. I agree, tx changes are difficult and I have apparently been lucky so far. Maybe you will be too. Fingers crossed.

There were no lung issues, but I did find out that AA has caused my blood sugar to shoot up. So my days of AA are over. I see my doc tomorrow to tell her I'm intolerant of all these SE. I wonder if she'll put me on Xeloda.