Grade 3 but no chemo treatment

Are you strongly er and pr positive? If you are have the oncodx test to see what the risk is. If you are er, pr negative you will probably be advised to do chemo. Chemo is most effective on fast growing cells.

HER2+ is more associated with automatic chemo. Other factors include tumor size and whether or not there is lymph node involvement, which you won't know until after surgery. Assuming the lymph nodes are clear, you'll probably have an Oncotype test to see if chemo would be beneficial.

Anxious, the pr at 2% might drive the oncodx score up. Let us know good luck to you. You should ask if AI drugs would be better for your case.

Anxious I had a single mastectomy left side. I had 2 tumors 1 IDC 1ILC both 1 cm separate tumors. I am 95% with er and 0% with pr, her2- and no nodes. Seven years out, no cancer.

I had a DIEP reconstruction and a lift on real side. I am very happy with the cosmetic result.

One of my tumors was grade 1, a 5 of 9 on nottingham, mitotic rate 1. The other was grade 2, a 6 of 9, mitotic rate 1.

I couldn't feel the tumors, neither could doctors, they were close to the skin surface. I was told no skin sparing, simple mastectomy was the board recommendation. The pathology after mx was really excellent considering. My surgeon said it was a very good report he was confident there were no lingering concerns. However, as you know there is no way to know for sure. Chemo was recommended after oncodx scoring. Everything I have learned since then has pointed to my absence of progesterone receptors with a high er percentage. This case has been seen as aggressive and not as responsive to tamoxifen. One theory suggest my cancer my have stopped feeding on estrogen but most of those cases are grade 3 and her2+. Impossible to know if my tumors feed on estrogen. Studies have shown AI drugs to be much more effective than tamoxifen for er+ pr- cases.

hi there,

I was grade 3, and was offered chemo. I had a couple consults. One Onco said def yes as I was onmy 45, another said I'd be fine without it. I elected to go without. I am 8 years out and doing well. I didnt have lymph node involvement and if I did, my choice would have been different.

Good luck to you.

I was diagnosed at age 26 with Stage 1 grade 3 IDC Er+ Pr+ HER2- with clear margins and no node involvement. I didn't go through chemotherapy however I am on tamoxifen. I agree with Bevin if I had node involvement my decision would've been a different story. Have you decided on your surgery? Lumpectomy or mastectomy?

I had a bilateral mastectomy done March 5, 2018 with tissue expanders placed. I just recently got my expanders exchanged for implants August 14, 2018. My reasoning for getting the bilateral mastectomy and not the single mastectomy or lumpectomy was reassurance. I didn't want a single mastectomy because I didn't want to chance getting cancer in the other breast. Lumpectomy was out of the question. Are you interested in reconstruction surgery?

That's completely understandable it's a difficult decision. You should consider a skin sparing bilateral mastectomy that way when you do decide to do reconstruction there is extra skin there for you to stretch. Unfortunately recurrence is possible even with a mastectomy. It doesn't eliminate the chances but it does lessen it. Which is why the bilateral was worth it to me. Once a year you would have to get screened (MRI).

hi yes, I did take hormonal therapy and 36 rounds of radiation.

Sorry to hear that your Oncotype score is high Anxiouslady. Wishing you strength right now.