LUPRON

hi! Anyone else out there on Lupron?

I am not sure there's a thread for this but I find that it is a pretty hearty medication and thought I would make a space to discuss, compare notes, ask questions, etc

I had a shot last Wednesday and have had a ull headache ever since. Does anyone else experience the Lupron headache and how do you remedy? Tylenol and Advil don’t seem to make a dent. I realize this could also be from the Ibrance or AI I am on, but it seemed to correlate with the injection.

Best wishes to all

dear Love,

Sorry you're experiencing a painful headache!

I definitely had a strong headache/ tinnitus after initially going on Lupron. I was on it for one year, during which the discomfort from the drug subsided. It took a bit of time for my body to adjust for sure.

LovefromPhilly-

"Industrial strength hot flashes"- I like that. So true. I know what you mean about feeling them come on.  I can feel my face get hot- I looked in the mirror once when it starts and my face gets red.  Then my heart races. Then I kind of feel anxiety- like I want to run around the house.  Then Boom--sweating head to toes. Literally dripping sweat, rolling down my back, rolling down my legs from behind my knees. Hair wet.  Crazy.

Have you ask your MO about the headaches? What you should take for them?   

so far I’ve tried Tylenol and Advil.

I’ll ask about it at next appointment in about 3 weeks :-)

In a weird way I am glad to know I am not the only one getting the Lupron headache

I know!!! I have done some research and western medicine cannot exactly explain what it is all about yet.

However there is some connection between the neuroendocrine systems .

From the neuron end, norepinephrine and epinephrine aka NE and EPI (our fight or flight neurotransmitters) are major players with the hot flashes. I haven't figured out from the endocrine which is the culprit - I think I read somewhere that it has something to do with luteinizing hormone? I haven't quite got that one figured out. Why is the luteinizing hormone flaring??? It has something to do with ovulation...I need to revisit some of my notes

Hence, with the NE and EPI, caffeine and stress can trigger a hot flash. Also, alcohol makes them worse but I'm not sure what the role of ETOH is quite yet in getting involved because typically alcohol is a depressant, not a stimulant. So not sure!

I will keep searching. That stomach drop is the worst when it wakes me up like 4-6 times a night!! Ugh!

I am pretty sure it’s the Lupron. I had the same reactions for the first couple of months. Try, if you can, to remain calm and rest as much as you need to. Take Tylenol and call you MO to let them know what’s happening.

I can’t say for certain but I believe, for me, it was part of a healing reaction that my body and the cancer tumors were having to the medication. I tried to see it as a positive, even though it sucks.

I cried a lot and had a low grade fever from the meds at first. It did end up calming down after a few months. Now I barely notice the shots.

Hang in there luv. Sending healing light visions surrounding your body! ♥️♥️♥️💛💛

Hi everyone, can you tell me what dose of lupron are you on? I used to be on 22.5mg. However, my new MO only prescribed 11.25mg this time. I asked them why & they said women only needs 3.75 monthly or 11.25 every 3 months to suppress ovaries. He said they only used 22.5mg for prostate cancer. Thanks in advance for your input

Thank you Figtree.