Tamoxifen and Endometrial/Uterine Cancer

Options
maryny16
maryny16 Member Posts: 19
edited January 2018 in Hormonal Therapy - Before, During, and After

Did anyone get uterine cancer from Tamoxifen or other treatments? Going in for a DNC this week b/c my uterine lining went from a 5 to a 21 and had abnormalities. Never had any fibroids or endometriosis previously so they said it's clearly a result of the tamoxifen.. I have only been on Tamoxifen for 6 months too. Anyone else been through this before? Do they usually suggest removal of the uterus ? Can you still stay on Tamoxifen if you remove your uterus? I had sever side effects with Lupron and Arimidex so I would like to stay on Tamoxifen but am now worried about it's effect on my uterus and possible uterine cancer.

thank you for any advice !


· Share on FacebookShare on Twitter

Comments

  • Meow13
    Meow13 Member Posts: 4,859
    edited January 2018

    My SIL got the ENDO cancer from tamoxifen. Her doctor ignored her till it was too late to save her life.

    She had tumors she could feel. They immediately took her off tamoxifen after she insisted on a biopsy. Then chemo, surgery more chemo.

    Don't ignore it I would suggest getting a couple different oncologists opinions. Getting cancer from tamoxifen is rare but it does happen.

    · Share on FacebookShare on Twitter
  • maryny16
    maryny16 Member Posts: 19
    edited January 2018

    I am so sorry to your sister in law had to go through all of that...thank you for sharing.


    · Share on FacebookShare on Twitter
  • Jen987
    Jen987 Member Posts: 145
    edited January 2018

    I just had a endometrial biopsy yesterday. My lining doubled from last year. This is the second biopsy I’ve had in 4 years. I’m hoping the results are negative again this time around.


    Cancer - the gift that keeps on giving

    · Share on FacebookShare on Twitter
  • Maureen1
    Maureen1 Member Posts: 614
    edited January 2018
    • So sorry you have to deal with this..my endometrium more than doubled in thickness after a year onTamoxifen but thankfully the biopsies were negative for endometrial cancer. My GYN recommended a hysterectomy since I wanted to stay on the Tamoxifen and I had a very large fibroid in addition to the thickness but no cancer. I wish you the best (((hugs))) Maureen
    · Share on FacebookShare on Twitter
  • maryny16
    maryny16 Member Posts: 19
    edited January 2018

    Thank you for sharing your stories. Jen - good luck with your biopsy.

    I was on Lupron and AI for 8 months so they put me into menopause and then took me off, went back into premopause (I am 48) and then started Tamoxifen 6 months ago. 21 cm is pretty thick. It is so painful too! Maybe the switching treatments had a negative effect - or can only 6 months of tamoxifen cause that many problems? My previous lining was 5-6 cm 18 months ago. Praying for it to be benign.

    Maureen - if I am clear I am going the hysterectomy route too as I hope to stay on tamoxifen as AI and Lupron I couldn't tolerate.

    · Share on FacebookShare on Twitter
  • teachermomfl
    teachermomfl Member Posts: 104
    edited January 2018

    Very interesting thread. I was diagnosed with ADH last month. Excisional biopsy will be Feb. 2. My surgical oncologist said if there is no upgrade, he’d like to put me on Tamoxifen for the ADH. I had an ablation three years ago, so I worry about the reports of endo lining thickening. I had a thick lining and uterine polyps when they did the ablation

    · Share on FacebookShare on Twitter

Categories