SUV of primary tumor and prognosis

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stephilosphy00
stephilosphy00 Member Posts: 386
edited March 2017 in Stage III Breast Cancer

I found an interesting article about the strong relationship between standardized uptake value (SUV) of the primary tumor and progression-free survival (PFS).

Prognostic Value of Primary Tumor Uptake on F-18 FDG PET/CT in Patients with Invasive Ductal Breast Cancer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC40430...

I know most of the BC patients don't get PET/CT at diagnosis. Somehow I did and the SUV of my 2.7cm primary tumor was 5.4. This article indicates that a pSUVmax of 6.6 to be the optimal cutoff for predicting PFS. The patients with a high pSUVmax (more than 6.6) had significantly shorter PFS compared to patients with a low pSUVmax.

What do you think?

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  • sbelizabeth
    sbelizabeth Member Posts: 2,889
    edited March 2017

    It's interesting research. Probably not easy to track in a general population of newly diagnosed patients, because, as you said, not many receive PET/CT after diagnosis and before treatment. I got one after my initial lumpectomy, which we thought would be like popping out a little tic-tac, revealed multiple positive nodes. Thankfully, this is not a common occurrence.

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  • YATCOMW
    YATCOMW Member Posts: 664
    edited March 2017

    Very interesting....... I am going to dig out my old reports and see where I was at......

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