Specific recommendations that have worked for side effects from hormonal therapy. How to deal with nausea, tiredness, etc.

I would specifically like to hear about any new and promising upcoming treatments for metastasic breast cancer. And particularly IBC that has returned. Thank you.

I think some segments on the types of exercises to help women coming in to recovery after treatment. There are some very specialized exercise programs these days like yoga for breast cancer patients (and fyi, I am planning to get certified to do this in the next few years!)

I'd like to discuss this recent news article. https://breastcancer-news.com/2017/02/22/breast-ca...

Women Getting Breast Cancer Radiation Therapy 10 Times More Likely to Develop Second Primary Lung Cancer

I’d like to hear about the mechanism by which obesity affects estrogen production in postmenopausal (or older male) patients. I’d also like to hear more about exactly what aromatase inhibitors do—do they reduce the amount of aromatase that the liver produces? Or do they somehow “spoil” (inhibit or inactivate) or destroy the aromatase so that it can’t convert androgen to estrogen? And does ingestion of alcohol inhibit every liver function—not just “clearing estrogen from the body” but production of aromatase as well?

Please correct me if I’m wrong. The androgen that aromatase converts to estrogen is produced by the fat cells (as well as the adrenals). And it is a known fact that except by surgical (liposuction, excision/tummy tuck) or cryonic (Cool Sculpting) means, fat cells can only shrink/be emptied when one loses weight. They can only be decreased (non-surgically or cryonically) in size, not in number. Fat itself is merely a substance within those cells, which can only be burned or remain static—it’s the fat cells themselves that act as a kind of gland or organ to produce the androgen. But when women gain weight, we add weight two ways: either hypertrophic (increasing the size of fat cells by filling them up with stored fat) or (unlike men), hyperplastic (we actually can increase the number, not just the size of fat cells).

Given that, I’d welcome a discussion as to the science behind aromatase inhibitors, the process by which alcohol is supposed to increase ER+ recurrence; and the possibility of the aforementioned surgical/cryonic ways to reduce the number and not just the size of fat cells--especially given women's ability to actually create new fat cells (and the possibility that, due to reduced metabolism caused by estrogen deprivation, weight gain on AIs might be hyperplastic and not just hypertrophic in nature).

Are there studies other than epidemiological/anecdotal into the interactions between and role of alcohol, fat cells and aromatase—and if so, can they be explained in sophisticated lay terms. Are any doctors speculating on the use of liposuction, surgical excision and Cool Sculpting to modify body composition both to compensate for AI-impaired metabolic rates and inhibit production of androgen? And other than via the extra calories in it, where is the harm in a glass per day of wine (for those who do not have any chemical dependencies)?

moresudies re: recurrence rates . Who is susceptible and why . Current scientific studies on recurrence .

Managing AI side effects - from prevention via consideration of fillers used my manufacturers to aches and pains, effect on bones, and hair loss (and everything in between). If we're to be on this med for 10 years, quality of life issues are very real. Holistic treatments are of great interest

Thanks for asking.

I would be interested in hearing about the psychological aspects, particularly how anxiety and depression after diagnosis are treated. It would be great if we could hear specific approaches to counseling patients. In my area our mental health providers don't have much experience in this area, and I think it would benefit patients who need to bring their provider a game plan to get started.

I would like to hear the latest thinking on multiple recurrences. Treatment and support options. It is very hard to find any research in this area.

Thank you

Yes to the above request for more discussion of weight management, etc., but informed by insight into the effects of near-total estrogen depletion (for those of us who are ER+) on our bodies and how that affects metabolism, etc.

In fact, an in-depth discussion ofnthe long-term effects of bc treatments would be of interest to me.

I'd also like a discussion of survivorship issues/planning and how to discuss these eith providers, especially PCPs, who may be somewhat clueless.

I agree with the above who suggested hormonal therapy, and the discussion needs to include the problem of vaginal atrophy and any treatments available to help (i.e. Mona Lisa Touch). There is very little information out there about the correlation of tamoxifen and vaginal atrophy, not even on this website.

Summaries of recent research. It might be something that doctors could listen to as well!

I'd like to hear about immunotherapy and its promise in treating breast cancer.

I would love to hear a podcast on the topic of the imminent changes to the staging system.

Dear Members,

I am a tiny particle in this messed up world, who is trying to eradicate anxiety and create health awareness. Breast Cancer is also apart of that. plz read my thought for those who is suffering and for those who is ignoring.

Breast Cancer is chronic disease. strong medical attention is require. But sometime your efforts also ease it to the greater extent. I am not against of medical supplements. For better result, try to use the herbs and food side by side. Do not replace home remedies with Medical treatments. In present time, most of the foods available are harmful. So you have to eat wisely and in self-control. Also you have to know the differences between good medicine and bad medicine.

The only person who can save you is you. You are stronger than you though you are. Everything is in your hand. Do not follow anything which promotes this type of chronic disease. Good luck. Quit alcohol and Think positive.