Radiologist and lab are stumped - what are cancer chances?
I'm 48 and have a history of "innumerable" breast cysts, including three very large and painful ones aspirated in 2006, 2011 and 2012. In fact I was so determined to do whatever i could to try and prevent them, I gave up caffeine in 2012. No small feat!
I just got a call this morning about results from a core needle biopsy of what I originally thought was another cyst flare up (indeed I do have a large simple cyst in the other breast) but these results, the doctor said on the phone that they are stumped, don't know what could cause this, and recommend surgery to remove it and be sure.
I thought I would post here in case anyone else has had a similar experience.
48 years old with recent menopause symptoms including two months since last period. Not on any treatment or meds or birth control. Flare up of cystic feeling pain in both breasts over two months, and then in both breasts I found lumps. While waiting for my imaging appointment one breast became red and extremely painful at the lump. Urgent care said infection, and prescribed antibiotics
MAmmogram and Ultrasound show simple cyst in one breast. But the other, the red breast, showed a solid mass. Though oval and smooth like a cyst. Aspiration attempted but no fluid came out. Core needle biopsy performed. That's the result I got today that the radiology doc is stumped about - says the lab results are benign but "discordant" with the imaging.
* cystic cells
*reactive inflammatory changes (though no current infection)
* infarcted/dead tissue -- not necrotic, she says it's like the blood supply was cut off. But I have had no trauma to the breast that I'm aware of
It seems like the infarcted tissue is what's concerning them. She says a cyst shouldn't have this.
She recommends surgery to remove the mass, to be 100% sure no cancer. which i will likely do to be sure. But any idea what would cause something like tor what's going on?
Comments
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If the lab results say that the results are B9 but discordant w/imaging, then the radiologist missed the area that they wanted to biopsy. Go and get it removed. It doesn't sound alarming with how it's described.
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Could it be a cyst with cellulitis?
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I would be surprised if she didn't get the right place because my breasts are very small (barely b cup) and the lump is large and literally visible to the naked eye. Also she took four core samples. On the phone she said that it was discordant with the imaging/what they expected? Anyway I think you are right that i should just have it removed to be sure -- and also for my own curiosity now haha -- but of course I'm really nervous about what's going on.
Re the idea of cellulitis, she originallly thought it was an abscess. But when when tried to aspirate it with a fine needle, no liquid came out. During the core biopsy there was also no puss or sign of infection. Though perhaps the antibiotics handled it? (It was a long wait for the imaging appt and I completed 10 days of doxycycline while waiting
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The Donna
After a radiologist performs a biopsy they too get the pathology report. An addendum to the biopsy report is then generated stating the results of the biopsy. If the rad thought it was a fibroadenoma and path thinks its a fibroadenoma, then the results are "concordant" and that is documented in the addendum. If the rad thought it was cancer, and path says its not, then this is a "discordant" result and further recommendations are made. This discordance triggers a review of the entire case to make sure what was seen initially is what was biopsied. If I saw a suspicious mass on imaging, and my biopsy result is "normal breast tissue" then I have to wonder if i missed the lesion. On the other hand if I saw this same suspicious mass and the path report came back "fibroadenoma" I would feel that I did hit the target but my interpretation of its initial appearance might have been a little off. Either way there shoud always be a recommendation accompanying the path addendum.
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Thank you. It turns out you are right. I went into the surgeon for the consultation and she was much more frank with me. The radiologist thinks it is cancer but the core needle biopsy results are benign. That's why it was discordant.
The breast surgeon does not think it is cancer but concurs with the recommendation of an excisional biopsy mainly because this will not go away on its own and may get inflamed/infected again in the future.
The surgeon did an ultrasound and we could see the clip that the radiologist put in, in the center of the solid part of lump, where the biopsy was taken. The surgeon showed me that there IS fluid at some of the (smooth) edges. She thinks it is/was a cyst and I possibly bled into it/burst blood vessel and now there's debris in it, and dead tissue (FREAKY!) and it may have been infected (I had been on 10 days of doxycycline prior to the imaging due to appointment scheduling). Thissounds so weird I asked how this happens. She says nothing I did or could do to prevent it, these things just happen?!?! But now that it's in the condition it is, it should come out.
Anyway she told me not to worry about cancer. She sees a lot and doesn't think this is it. But of course it will be tested to be sure.
I'm having it out on March 2. I'm 48 and it's the first surgery of my life so I'm a little nervous. But happy with her frankness and comforted that it is probably not cancer.
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your history sounds a lot like mine. I had my first surgery at 19 to remove what turned out to be a fibroadenoma. Then I had another one removed at 25. Then an aspiration in 2013, now I have a Bi-Rads 4 for 2 hypoechoic masses (one on each breast 1cm and 9mm). I am seeing the breast surgeon tomorrow.
Both the biopsies and the surgery were uneventful. The waiting for the results is what is the worse
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Just a short update. I had the surgery yesterday, an excisional biopsy. She took the entire lump but no surrounding tissue, since the breast surgeon thinks most likely it is not cancer. I will have results at my in-person follow up a week from today.
It has been quite a stressful two months -- trying to get an initial appointment, being given antibiotics, waiting for mammo and ultrasound, core biopsy, waiting on that result, and then the surgical biopsy. Even with the likelihood that this is benign it has still been a lot of appointments and stress, as well as some physical pain. The healthcare system isn't easy to navigate. Thankfully I have a job that allowed me time off for all these appointments and provides health insurance. I think about all the women who dont have that, the extra worry and stress.
Anyway thank you for the advice and greetings. The surgery itself wasn't bad at all, in fact to be honest the core needle biopsy was more difficult and I had about as much pain after! Anyone worrying about a surgical excision, try not to be scared, it was easy.
I'll come back to share the results.
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Hope the results are B9, E. Squirrel, and that you can put all of this behind you.
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Reading through the whole case...it really requires a lot of courage whats you been through. Wishing you good luck
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Good luck and please let us know the results either way
thanks !
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Thank you for the kind notes! Follow up appointment with results is this Friday morning. I will post results here, regardless of the outcome, in hopes that it may help others with a similar mystery.
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Result is benign! Details:
Diagnosis Left breast mass 4:00 excision:
1.2 cm extensive infarcted tissue, intraductal
Fibrocystic changes, chronic inflammation and microcalcifications, peripheral
Gross description: Mass like specimen 3x2x1.5 cm Cut sections reveal a well circumscribed hemmoragic fatty tissue nodule measuring 1.6x1.4
I'm not sure what it all means except that they diagnose it as benign, the surgeon says it's all good, incision is healing well, come back in six months for a follow up.
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Woohoo! Good news on a Friday, no waiting and worrying for you this weekend. Thanks for the update
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