Issues with Biopsy and results Spiculated spot

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HouseDivided
HouseDivided Member Posts: 21
edited September 2016 in Waiting for Test Results

Hi -I am a new poster. I've been lurking for a few weeks and found great info in this discussion board. I have an unusual situation, I think...

A quick history:

8/2/16 had a mammogram (last one was in 2010, I know, I waited way too long:-)

8/12/16 had a follow up mammogram as a spiculated spot was found on my right breast, they called radiologist and I went right to Ultrasound

8/16/16 got results of both tests: there is an 8.8 x 5.6 x 9 mm spiculated carcinoma within the 9:00 position of the right breast which warrants biopsy for histologic diagnosis.

BIRADS 4B (suspicious for malignancy)

8/23/16 had needle core biopsy with ultrasound guide with four biopsies. I was told it would take 45 minutes, it took an hour and a half and the entire time the radiologist seemed to lose the spot constantly and the ultrasound tech looked more annoyed as time went by and would nod to her when she found it again and then she would lose it. I could see the spot on the ultrasound myself as I was facing the machine. During the test the radiologist told me she had issues and if we didn't get the right cells they would bring me back for another biopsy using a different tool like a roto rooter that is painful for women so she didn't like to use it unless necessary. She told me they would redo it at no cost. I was an emotional wreck when I left there, not because of the possible diagnosis but because it took so long and I was not confident at all that she got the right spot.

My PCP left her practice during this so I decided to go right to an MO on my own prior to the biopsy coming back. I am glad I did.

8/25/16 Met with the MO and he reviewed reports and did an exam. I told him my concerns with the biopsy not being correct and he said if it came back benign there were other options. He agreed that this was most likely cancer.

9/1/16 Finally got Biopsy results 9 days after the biopsy. The MO's Medical Assistant had to beg to get the results for my appt. that day. Here is the FULL report:

Clinical History: ICD10 code N63. Infiltrative cancer, right upper quadrant.

Gross description: received in formalin labeled "right breast at 9 o'clock" is a 1.0 x 0.6 x 0.2 cm aggregate of yellow-tan fibrofatty core biopsies. The specimen is inked black and entirely submitted in cassette 1.

Microscopic description: sections reveal needle core biopsies of breast tissue. There is some increased fibrous stroma. No significant epithelial hyperplasia is present. There is no evidence of atypical hyperplasia or malignancy

Same radiologist read both mammograms, ultrasound and did the biopsy and reported on the biopsy.

The MO read me the results and I asked if they made sense to him and he said no and he had a call in to talk with the radiologist. He said she recommended a follow up mammo in six months and he was very uncomfortable with that. He said I should have another biopsy or see a breast surgeon in their practice. I said I would not go back to the radiologist but I would go to a breast surgeon. So I have an appt. in a week. He also ordered a DNA Analysis.

I have some questions for you experienced ladies:

Why would the mammo report say carcinoma before a biopsy was done?

Does the DNA Analysis test for the breast cancer gene?

Why would the biopsy report say infiltrative cancer (I have no history of cancer) and yet the findings say benign?

What were your experiences with an ultrasound guided needle biopsy? How long did it take? Did the radiologist have to fumble around looking for the spot?

It sounds like they would remove the spiculated mass whether it is benign or cancerous so why not go to that at this point and do the second biopsy in the lumpectomy?

Does the size of the mass listed on the mammogram include the spikes (which on the mammogram looked quite long like spider legs) or is that the measurements of the spot and the legs are extra?

What can I expect from the BS at this point?

I think that's it for now! I'm very frustrated trying to get properly diagnosed. I'd be thrilled if this was benign but I just want an accurate diagnosis at this point. BTW, I have never had breast surgery or an injury that I can recall that would leave a scar.

Thanks for letting me vent and thanks in advance for any input and advice!




Comments

  • ChiSandy
    ChiSandy Member Posts: 12,133
    edited September 2016

    As I interpret it:

    1. The “infiltrative cancer” is what they suspected it might have been, but more likely simply what they were looking for. “ICD 10” is the current (as of 2015) national standard system of billing coding for insurance &/or Medicare reimbursement, and in order to get coverage for a procedure, they have to say what the procedure is seeking to diagnose, using the proper specific diagnostic “code"--hence the “code N63” (anyone here who does billing coding, I’d appreciate clarification). It doesn’t mean that is the actual diagnosis, but rather the suspected diagnosis--without that, there’s a chance that they would not be reimbursed. “Inflitrative,” synonym for “invasive,” means that they weren’t looking for a tumor in situ, e.g., DCIS--they expected that were they to find something it would be invasive (more common, BTW, than in situ).

    2. The DNA analysis does not test for “the breast cancer gene” (which is a misnomer anyway--the correct terminology would be “genetic mutation,” which is a defect in a gene that causes cells to keep dividing and form a tumor, instead of dying off at the end of their lifespan like normal cells do). If by “breast cancer gene” you mean such a mutation (e.g., of the BRCA-1 or -2, CHEK 2, PALB 2, etc. genes), that is done by taking a blood sample (sometimes saliva sample if you can’t give a blood sample or you can produce copious saliva uncontaminated by other stuff in your mouth), because those genes--and their mutations--are evident in all your cells and the blood is the most reliable way to test for them. It is done independently of biopsy, after a genetic counseling session--and usually only if there is a reason such as a close family history of breast or related cancer, other family members who tested positive for such a mutation, or a pre-existing breast cancer diagnosis coupled with an ethnicity (e.g., Ashkenazi Jewish) in which such a mutation occurs more frequently than in the general population. The "DNA analysis" the report mentioned is to analyze the biopsy sample itself to determine the nature of the tumor cells, which is another measure besides appearance to distinguish benign from malignant.

    3. The findings say “benign” because even though they were looking for invasive cancer, cancer isn’t what they found. (That doesn’t mean they expected to find it, but rather, as in 1 above, they had to say that’s what they were looking for in order for the tests & procedure to be covered).

    4. My core needle biopsy was quick, painless and easy. The radiologist (not the same one who did the diagnostic ultrasound that revealed the mass) used the diagnostic film as a guide as to where to put the probe, found the mass and hit her mark right away. She specializes in breasts (as did the diagnostic radiologist) and nothing but, and it was in the Center For Breast Health of the hospital which also has Kellogg Cancer Center. Sorry your experience was not as good.

    5. The mass was bigger than the core samples, and removing it would have been a surgical procedure. Even minor surgery carries risks (anesthesia, infection, clotting, pain, etc.), so diagnostic procedures tend to be as minimally-invasive as possible. No need to put you through the equivalent of a lumpectomy only to find you don’t have cancer.

    6. Tumor measurements usually include the whole enchilada, including the “spider legs;” but another reason to do just a core needle biopsy rather than a surgical excisional biopsy--because were they to remove the entire tumor, they’d have needed to take a wider margin to make sure that they got it all.

    7. What you should expect from the BS depends on the BS’ preferences. You would probably receive an explanation of the results and his/her opinion about what if anything to do about them--most likely, confirmation that periodic non-invasive diagnostic surveillance is advisable. It would also depend on how much faith the BS (and perhaps the MO who disagreed with the radiologist) has in the pathologist who examined the core biopsy samples; it’s possible that the BS might suggest a second opinion (rather than putting you through another biopsy) from another pathologist or lab, using the samples already taken. MOs don’t usually call the shots about whether a tumor is or isn’t malignant, but rather how to treat it once it’s removed and confirmed to be cancer. A good way to go would be to get an opinion from a facility that actually has a “tumor board” of surgeons, MOs and pathologists--and perhaps this BS is part of such a facility. If not, request such a second opinion that has such a board.

  • HouseDivided
    HouseDivided Member Posts: 21
    edited September 2016

    Hi ChiSandy - thanks so much for your reply, very helpful!

    I wanted to clarify the DNA Analysis, this was a bloodtest that the MO ordered after the biopsy results, this is a different facility than the radiology center that did the biopsy. So they wouldn't have access to the samples. That's why I wondered what they might be testing for.

    My concern is that the radiologist actually got the right spot, even she wasn't sure. So while the results sound good, I want to be confident in them. With 90% of spiculated masses being cancerous, I want to make sure. I think your idea of a second opinion for the samples already taken would be perfect except my concern is not about the reading of the results, it is whether the biopsy was actually taken from the right spot. Sounds like I may be stuck doing a second biopsy with a different radiologist.

    I had read on this forum and online research that if it were a benign radial scar, that they would recommend removing it. That is why I questioned doing a second biopsy if the end result is to do a lumpectomy anyway. But I do understand the concern over unnecessary surgery and certainly don't want it unless necessary.

    Sorry for all the questions, just trying to figure everything out, I really appreciate your response and anyone else's experiences.



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