Ibuprofen to reduce recurrence of breast cancer.
I have just watched a video on youtube stating that perhaps use of anti-inflammatories such as aspirin or ibuprofen daily might actually prevent a breast cancer from coming back.
Does anybody know anything more about this? How often should one take the ibuprofen in a day? Once, twice?
Am really interested to know more about this.
Dolly
Comments
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At my yearly check up last Sept my onc asked if I took an aspirin every day. She had just returned from a bc conference and this had been discussed. She said studies are showing that taking a daily aspirin or ibuprofen is reducing the chance of recurrence.
Since I was already taking an aspirin daily for a heart issue, I just considered this another good reason to continue.
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Hello Luv,
I am amazed at this. Just watched a very interesting video and the doctor on it was saying that if an anti-inflamm is given prior to the operation to remove tumour then there is a massive drop in chance of recurrence. It's to do with inflammation and wound healing and something to do with tumour cells multiplying during the months immediately after the op.
So am I correct, that all I need to do is take one aspirin or one ibuprofen? What amount of aspirin do you take (mg)? I am going to start this immediately.
Dolly
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You'll be oredered to not take aspirin or ibuprofen prior to surgery to prevent bleeding, so you shouldn't do that.
Dolly, look at this thread on Toradol at surgery helping to prevent recurrence as I think it is more what you are reading about. There are also multiple threads about aspirin after surgery if you use the Search function.:
https://community.breastcancer.org/forum/73/topics...
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a baby aspirin a day has been proven efficacious, but daily I buprofencould cause internal bleeding. Best check with your doctor.
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Thanks for this info ladies. I had never heard of this! Will defo be finding out at next appointment if it is OK to take aspirin.
Dolly
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My MO and PCP are enthusiastically onboard with a daily baby-aspirin (which I take for cardiovascular health) and 200 mg. of celecoxib (a COX-2 inhibitor, which is a form of NSAID that is much easier on the gut). I take the celecoxib (brand name Celebrex) for chronic hip bursitis from a gluteal tear incurred while shoveling snow, which bursitis flared up again after starting letrozole--and to manage my AI-induced trigger thumb for as long as possible before opting for a cortisone shot or surgery.
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what is a baby aspirin?
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Dolly, a baby aspirin is 83 mg and is used by adults to help with heart health. They are normally orange and taste quite good. I'm sure they have made and adult version of a baby aspirin that probably says something like "daily for heart health". It kind of acts like a blood thinner but not in a serious way. You can take it every day and not compromise your stomach, but be careful if you're adding it in with other meds, make sure your PCP knows you are taking it.
I've been taking anti-inflammatories since before my breast cancer and I recurred, so I don't hold much weight in the study. They are just lumping breast cancer in with "inflammation" which it isn't, really. You could just as easily say people who eat cheese have a higher chance of recurrence and someone who ate cheese and recurred would say, Yes!!! They are just throwing darts at the wall....
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I take the 81mg “heart-health” variety, which is enteric-coated and unflavored--meant to be swallowed, not chewed.
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I had the Toradol (ketorolac) injection at surgery pre-incision, and then I took Toradol orally for 4 days after (you can't take it longer than 5 days at a time due to side effects). I had no problems with bleeding but it was quite a task convincing the surgeon to do it. There is a theoretical risk of bleeding that most of them don't want to contend with, but sassy has posted some refuting research on the Toradol thread that helped me convince the surgeon. She made all kinds of notes in my chart about how she was doing it at my insistence against her better judgment. Found one anesthesiologist who was more than willing to do it. He didn't think the injection that close to cutting would have enough time to cause problems. That said, there was another member who had surgery at the same time I did who did have bleeding problems. No one knows if it was caused by the Toradol but if you have low platelets or platelet dysfunction then you are probably not a good candidate.
I think everyone knows this but I just want to restate it because I think it can get lost in our individual struggles. Statistics apply to groups of people and don't mean much on an individual level. Just because one or more people recurred when the statistical risk was supposed to be lower for whatever reason, does not negate the research that found a benefit for the group. The risk is never zero, but it is worth doing everything you can to lower your statistical risk because some people will benefit. If you don't try because of another individual's unfortunate experience you are denying yourself the opportunity to fall into the group that does benefit.
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I take a chewable low-dose aspirin because there were studies that found enteric-coated aspirin is less effective, especially in overweight individuals. The research wasn't specific to breast cancer but better safe than sorry is my approach to just about everything.
Enteric-coated aspirin is less potent than plain aspirin
They suggest a higher dose if you have to take the enteric-coated for some reason.
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Thanks for all this information. I am going to look into this further and ask my oncologist about this and see what I can take.
Dolly
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solfeo, I took Torredol for over 3 years with no side effects. I guess I was a lucky one.
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