BC tumor growth is dependent on lipid availability

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http://www.eurekalert.org/pub_releases/2016-04/ifr...


Researchers discover that breast cancer tumor growth is dependent on lipid availability

In an article published in Nature Communications, scientists at IRB Barcelona reveal that breast cancer cells require fatty acids from the extracellular environment in order to continue proliferating


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  • peacestrength
    peacestrength Member Posts: 690
    edited April 2016

    mmmmm...my mind goes directly to using statin drugs for this. Am I reading this correctly? Lipids are part of the cholesterol cascade, correct? If so, a simple statin drug could be used to target this?

  • cp418
    cp418 Member Posts: 7,079
    edited April 2016

    http://integrativeoncology-essentials.com/2013/11/...

    http://science.sciencemag.org/content/342/6162/109...

    peacestrength - you may find these links interesting. I had previously posted them on a cholesterol topic thread. My understanding is not all statins are alike if you research them. Some types have been implicated as a link to BC and others to decrease risk. So I've been taking a plant based phytosterols supplement to lower my cholesterol level.

  • cp418
    cp418 Member Posts: 7,079
    edited April 2016

    https://www.sciencedaily.com/releases/2016/04/1604...


    How a metabolic pathway promotes breast cancer metastasis

    A metabolic pathway that is up-regulated in some breast cancers promotes the disease's progression by activating a signaling protein called Arf6, according to a paper. The study suggests that statin-like drugs may be effective treatments for breast cancer patients whose tumors express high levels of Arf6 signaling proteins.

  • cp418
    cp418 Member Posts: 7,079
    edited April 2016

    http://www.news-medical.net/news/20160406/Blocking...


    Blocking of LIPG activity could arrest breast cancer growth

  • peacestrength
    peacestrength Member Posts: 690
    edited April 2016

    Thanks cp418...following....will read the other info you've shared

  • VShapoval
    VShapoval Member Posts: 1
    edited April 2016

    LIPG Activity, Breast Cancer and Father of Oncology. Today we know that breast cancer is a kind of cancer that develops from iron-overloaded breast cells; all breast cancers are caused by iron-related genes (genes directly/indirectly involved in iron metabolism) and iron-related events (when excessive iron accumulates within cells), the Father of Oncology says. It is hard to say why one person develops breast cancer while another does not, experts say. It was already known that cancerous cells reprogram their internal machinery to produce greater amounts of lipids, scientists argue. Blocking of LIPG activity could arrest breast cancer growth, researchers report. According to the Bible, cancers and infections love iron. LIPG-researchers, scientists and experts love money, the Father of Oncology explains. Born in 1911, and dying in 1996 from breast cancer, Legendary Bulgarian prophetess Vanga predicted 9/11 and ISIS. Oil will stop, humanity will discover a new kind of energy (lunar helium-3 is a fuel for small suns), cars/trains will fly and religions will unite. Humanity will stop the cancer epidemic and the AIDS epidemic, but a new disease will be worse than cancer and AIDS, Vanga said. Different types of breast tumor may need different types of anti-iron treatment. The size and location of the tumor, along with the need for a margin, can often dictate if surgery is possible or not. All too often, inoperable cancer kills with appalling speed. The metastatic cascade is known to involve multiple steps. Metastatic breast cancer (stage 4 breast cancer) is usually more difficult to treat than cancer that hasn't spread. Micro-metastases are defined as deposits of tumor cells that measure more than 0.2 mm but less than 2.0 mm. Early detection of disseminated tumor cells (DTCs) might help to identify patients in need of additional iron-deficiency therapies (special diets, blood donations) after successful surgical resection (ceramic blades) of the primary breast tumor. Iron-deficiency therapies are aimed to prevent metastatic relapse. Fine-needle aspiration biopsy is the simplest type of breast biopsy. The needle is attached to a syringe that can collect a sample of cells. Fortunately, we can use biopsy technology: personalized direct intratumoral injections of iron-deficiency substances (ceramic needles) can eliminate inoperable tumors/metastases. Biblical iron-deficiency substances: 1) olive oil and sulfur/sulphur/S; 2) water and sulfur (water containing hydrogen sulfide, commonly called sulfur water). Iron deficiency is the enemy of DTCs, micro-metastases, antibiotic-resistant bacteria and HIV (slow viral infection). Doctors can successfully neutralize precancerous and cancerous cells, ALS (a form of cancer), some bacteria and HIV. All cancers and HIV can be treated with iron-deficiency therapy in hospitals. Cancer patients and HIV-infected patients should not self-medicate. http://www.medicalnewstoday.com/opinions/194982

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