Tamoxifen and irregular periods

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Angel123
Angel123 Member Posts: 62
edited December 2015 in Hormonal Therapy - Before, During, and After

I have been on Tamoxifen for almost four years. After a year, I had an early period. I had to go through a uterine biopsy (ouch!) an ultrasound and had 2 polyps removed. Well I got my period early again, just 4 days after finishing it and here we go again. I just had another uterine biopsy yesterday and am getting an ultrasound next week. I am nervous yet again. Has anyone had periods close together while on Tamoxifen and it was nothing? I guess I am looking for words of encouragement while waiting to get through the testing.

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  • funsizejen
    funsizejen Member Posts: 93
    edited December 2015

    Me! My periods have been crazy in every way since Tamoxifen. I've had numerous biopsies, and everything is fine. I'm blaming Tamoxifen, and possibly perimenopause. No fun.

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  • Angel123
    Angel123 Member Posts: 62
    edited December 2015

    Thank you for letting me know. I have an ultrasound tomorrow and I am so tired of having anxiety over it. Knowing what you said, really may help me sleep tonight. Thank you so much. I hope you don't have too much longer on Tamoxifen. I have exactly one year and 1 month left of it. BTW, I am in the same situation as you; Tamoxifen AND perimenopause.

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  • farmerlucy
    farmerlucy Member Posts: 3,985
    edited December 2015

    I bled for months on end with Tamoxifen. It does do a number on your uterus but thankfully uterine cancer is so very rare like 1/1000 and tamoxifen increases it to like 2/1000. Perimenopause plays so many tricks of it own. It is all such a pain, but the odds are greatly in your favor that it is nothing.

    I did end up doing an ooph and a d&c. All was fine. Then I went on Femara for seven months, and now I'm back on Tamoxifen. It is a welcome relief to me to have some estrogen.

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  • Angel123
    Angel123 Member Posts: 62
    edited December 2015

    Thanks Farmer Lucy. I noticed you had a Prophylactic ovary removed. Was that connected to the bleeding? I am glad you are doing better having some estrogen.

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  • farmerlucy
    farmerlucy Member Posts: 3,985
    edited December 2015

    Angel - yep I decided once and for all to become post meno, reduce my small risk of ovarian cancer, and move to an AI which can be a bit more effective. The bleeding did stop but it took about four months post ooph. Little did I know I'd miss Tamoxifen!!

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