Pathology Report ?

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98765
98765 Member Posts: 16

What does SR15-4757, Block A2 mean? I have IDC, 9mm, moderately differentiated, estrogen and progesterone positive and Her2 negative. Please help!!!

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  • MelissaDallas
    MelissaDallas Member Posts: 7,268
    edited August 2015

    I think it is just the labeling ID for the pathology specimens

  • dtad
    dtad Member Posts: 2,323
    edited August 2015

    I agree. No significance. However the other stats sound encouraging!

  • Moderators
    Moderators Member Posts: 25,912
    edited August 2015

    Hi 98765,

    You may be interested in checking out the main Breastcancer.org site's section called Your Diagnosis, which walks you through what each piece of your pathology report means for you, including size of the cancer, hormone receptor status, HER2 status and much, much more.

    You also may want to read the section on IDC for more info on how this type of disease is treated and what to expect.

    We hope this helps! Good luck on your journey and please keep us posted with how you're doing!

    --The Mods

  • 98765
    98765 Member Posts: 16
    edited August 2015

    Are they encouraging? I don't even know what I'm saying when I tell people my stats. I am really worried about moderately differentiated. That sounds bad.

  • MelissaDallas
    MelissaDallas Member Posts: 7,268
    edited August 2015

    Have you Googled/researched what that means?

    What does it mean if my carcinoma is well differentiated, moderately differentiated, or poorly differentiated?

    When looking at the cancer cells under the microscope, the pathologist looks for certain features that can help predict how likely the cancer is to grow and spread. These features include the arrangement of the cells in relation to each other, whether they form tubules, how closely they resemble normal breast cells (nuclear grade), and how many of the cancer cells are in the process of dividing (mitotic count). These features taken together determine how differentiated the cancer is (and its grade – see below).

    Well-differentiated carcinomas have relatively normal-looking cells that do not appear to be growing rapidly and are arranged in small tubules for ductal cancer and cords in lobular cancer. These cancers tend to grow and spread slowly and so have a better prognosis (outlook).

    Poorly differentiated carcinomas lack normal features, tend to grow and spread faster, and have a worse prognosis. Moderately differentiated carcinomas have features and prognosis in-between these two.

  • 98765
    98765 Member Posts: 16
    edited August 2015

    I am trying not to google anything because it scares me to death. I would rather hear it from those who have been through this. :)

  • MelissaDallas
    MelissaDallas Member Posts: 7,268
    edited August 2015

    Googling a factual specific term and seeing what NCI or Mayo Clinic saysis different than googling "cancer" and getting your information from "Dr. Quack.com."

  • Moderators
    Moderators Member Posts: 25,912
    edited August 2015

    98765,

    If you follow the link we sent you earlier, you can read up on what differentiation means, on the Cell Grade page. Breastcancer.org is a medically-reviewed, well respected informative site, so any information you receive here should be helpful!

    Let us know if you have more questions -- we're always happy to help!

    --The Mods

  • dtad
    dtad Member Posts: 2,323
    edited August 2015

    That means grade 2. The grades go from 1-3. Just one of the many characteristics of the tumor.

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