Stage I but grade 3

Yes less than 2 cm no nodes. The grade 3 may seem scary but there are treatments that may work very well on your cancer. You may want the oncodx or symphony tests if you are hormone positive.

Sites like cancermath, predict.uk, and adjuvant online can give you an idea re: recurrence risk. Also you could always get a second opinion on the pathology from somewhere like Johns Hopkins. If your oncologist is ordering the oncotype dx that will give you a better idea of the aggressiveness of the tumor. Grade can be subjective to the pathologist.

It is scary, but hang in there! The fact that you are er/pr positive is good news! You may want to ask for the oncotype test? When do you meet with you MO? They will help you understand the recurrence rates and what the best treatment plan will be.

Waiting-to-exhale.....my BS was never overly concerned with my grade 3 status. Clear nodes, clean margins and tumor removed. I read somewhere that grade 3 responds well to hormonal treatments.

hummingbirdlover...My oncotype score was 24. My BS ocologist still did not recommend Chemo. I even had the mammaprint done...came by high/low....still did not think Chemo was the right course for me. I was 59 at the time and post menopausal...had been since I was 43. My BS onco is the head of the Breast Center I go to and he said that studies would be coming out soon to support the AI treatment for my particular case. Of course I did not want Chemo...so I was good with that.

He said grade is just one piece of the puzzle...you have to look at all the factors and determine what's best. Also the oncotype is good at predicting chemo if your score is really high....like 30 or better and not needing chemo if it's low. When it comes to the gray area it's a crap shoot. Also, some women just choose aggressive and others not. My BS said if I wanted to talk with a MO about chemo he'd set the appt up for me....I declined but only because he felt strongly that it was not right for me. Other than BC I am in good health, and have never been on any medication until now.

I'm on Femara and so far so good.

Good luck KleeKai. It is a poor consolation but your Oncotype score would indicate not only that you need chemmo, but that your tumor will benefit from it, so you can be certain that you are helping yourself while you endure the treatment...

I had grade 3, 1.4cm, high KI67 tumore, and LVI but my Oncotype on the biopsy sample was 8. I have been so nervous and afraid to believe this that I got a third opinion who ordered a retest on the surgical specimen- and just heard it was an 8 too. it doesn't make sense, but that is what they got, twice. No chemo, and I am doing Femara.

For anyone with a grade 3 who is reading this, the Oncotype company told me that 30% of grade 3's get low scores.

Chemo works best on rapidly dividing cells so I gather that higher scores do mean chemo will work well, and for lower scores, chemo will do more harm than good. The TailorX trial (I think it is called) might soon shed some light on what intermediate scores mean for chemo.