On Coumadin

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sunseta1969
sunseta1969 Member Posts: 33
edited January 2015 in Just Diagnosed

I was diagnosed with breast cancer Christmas Eve. I have seen my general surgeon and a plastic surgeon. Due to family history and my own health, I am having a double mastectomy with reconstruction. I was diagnosed with fybromyalgia and chronic fatigue in 2011. In 2008 I had a large DVT (blood clot) and discovered that I have a protein C deficiency. I have to be on Coumadin for the rest of my life. So for my surgery to take place, I have to be off the coumadin for 5 days and they are talking about using bridge lovenox shots. I was just wondering if anybody else is a lifetime taker of coumadin and has gone through the surgery?

Thanks!

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  • Spookiesmom
    Spookiesmom Member Posts: 9,568
    edited January 2015

    That would be me. Had multiple DVTs, and PEs at the same time. Hospital and heparin for 3 days, then lovenox shots, then COUMADIN. The shots are a PITA, will leave nasty bruises. Just remember to pinch up and go in on an angle.

    As for surgery, or any invasive type procedure, you must stop taking prior. Yes, it's scarey not taking it. But with your docs ok, resume when s/he says.

  • sunseta1969
    sunseta1969 Member Posts: 33
    edited January 2015

    Thank you for your reply Spookiesmom. One more question if I may? Did you have trouble with the healing due to being on Coumadin?

  • Spookiesmom
    Spookiesmom Member Posts: 9,568
    edited January 2015

    not a bit. I was called away, meant to tell you I have Fibro too, the surgery didn't make that worse either.

    Best wishes

  • sunseta1969
    sunseta1969 Member Posts: 33
    edited January 2015

    Thank you! I really appreciate your reply.

  • DocBabs
    DocBabs Member Posts: 775
    edited January 2015

    Am I correct in assuming that you had a filter put in after you DVT in 2008? If so you will be fine being off coumadin for awhile. You will be up and walking quickly after surgery. Recovery should not be a problem.


    Barbara

  • sunseta1969
    sunseta1969 Member Posts: 33
    edited January 2015

    I did not have a filter put in. They did angioplasty 4x to try and shrink the blood clot and had to stop because I started with internal bleeding somewhere.....not sure where. They had to put a stint in because the blood vessel kept collapsing. The last US I had for the blood clot showed that from the stent down quite aways I am totally blocked. They told me nothing is getting through there. My blood has evidently routed other ways. But I am stuck with the blood clot unless I ask them to go in and remove the part where the clot is and sew the vein back together. Thought about doing that a few years back but just never got around to looking into it any further. I would still have to be on Coumadin and the damage to my leg is permanent.

    So, I am scared about the whole healing process. I don't heal as quickly anyway. And I'm having the DMX and TE's put in at the same time. I kind of feel like getting it all over and done with at once is better.......but still very scared.

  • Akitagirl
    Akitagirl Member Posts: 142
    edited January 2015

    sunsetata - I am also on a blood thinner of a different kind. It's called Eloquis and is a Factor Xa inhibitor. Much easier to take than coumadin and more effective. You don't have to get your INR labs checked...ever. I, however, chose NOT to bridge myself for my ALND and ended up having a TIA. Lesson learned. Make sure you bridge correctly with Lovenox!

    Warm Regards,

    Robyn

    P.S. Since you have to be on a blood thinner forever, you might want to ask your doc about the newer Factor Xa inhibitors. I lead the project management team for another company's product and know that there are now three out on the market. Eloquis is the best as far as study quality and statistical strength vs outcomes. If you watch television, you should see commercials for it. ;-)


  • Spookiesmom
    Spookiesmom Member Posts: 9,568
    edited January 2015

    BUT!!!!!! And it's a biggie. If you are injured, even a minor type cut, they can't stop the bleeding. The commercials don't tell you that. I'd rather do the INR and feel safer. A shot of vit K will stop THE COUMADIN.

    I've had 3 pharmacists tell me not to use this stuff, plus my PCP

  • leggo
    leggo Member Posts: 3,293
    edited January 2015

    Sunseta, your situation is by no way funny...I'm on a blood thinner myself, but spookiesmom post about the eloquis cracked me up. Every 60 second drug spot is 50 seconds of side-effects and somehow they still neglect to tell you that you could bleed to death. Gotta love those pharmaceutical companies. I've had a couple of surgeries since being on one (fragmin though, not coumadin) and it's been ok. Please try not to worry. They're very careful when they bridge you.

  • sunseta1969
    sunseta1969 Member Posts: 33
    edited January 2015

    Thank you all so much for the replies! I found out today that my surgery is going to be done on February 2nd. They thought they could get it in before the end of January but didn't have the OR time. My case did go before a review board and they all agreed with doing the BMX and reconstruction at the same time. I'll go off my coumadin on January 27th, and start my Lovenox on January 30th. Then I won't take anything the morning of the surgery. I also go see a geneticist today at 2:30. I talked to my nurse navigator this morning for about 45 minutes and I am definitely feeling better. Thank you again for all the replies and support!

  • Akitagirl
    Akitagirl Member Posts: 142
    edited January 2015

    Spookiesmom - Agree, there is no current antidote for this medication. However, I have been on it for over a year and have had several minor cuts and one major one from a figure skating accident that required sutures...the bleeding does stop. :-) I also am on chemo in combination with this and even with the lower platelets, if I cut myself or if my nose bleeds...it does stop. There have been no serious adverse effects or loss of life directly correlated to any of these Factor Xa inhibitors and their safety profile is BETTER than coumadin. There are no cases of anyone bleeding to death. However, there have been cases of transfusions needed for both patients on coumadin and on these newer meds. Furthermore, they are working on a antidote and are almost complete with trials that are looking at how to test the efficacy of this drug, as you cannot rely upon INRs or PT/PTT to measure effectiveness. Some people develop antibodies and hence this type of medication may not work, that is why testing is being developed.

    You are correct that there is an antidote to coumadin. However, as you are well aware, it is very tricky to keep your INR levels consistent, as this drug has many drug-drug interactions as well as drug-food interactions. These new drugs do not have the sensitivity or interactions with other drugs.

    By the way, I am not a drug sales representative. I am a research scientist who is accountable for the quality of design and execution of clinical trials within the cardiovascular therapeutic area.

  • Spookiesmom
    Spookiesmom Member Posts: 9,568
    edited January 2015

    Thanks for the info, still not convinced. Will continue as usual my COUMADIN level has been perfect for years

  • sunseta1969
    sunseta1969 Member Posts: 33
    edited January 2015

    Akitagirl, My Dr. talked to me about that drug a couple of times but he told me it was not approved for use for someone with a protein C deficiency. I don't know if that has changed.

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