Ovaries removed 2 years ago... MY ESTROGEN IS STILL HIGH?!?!
What could cause this?!
I am pretty thin... active... take femara... avoid soy like the plague... What's going on?!?!
Comments
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My doctors all pointed out that diet (not just ovaries) affects estrogen. Sugars, including processed carbs, and fats also produce estrogen--in fact for older folks like me they are the estrogen culprits to be avoided. And the more fatty tissue in a body, the more estrogen from any source can be stored, so fat-reducing exercise is another solution.
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Stumbled across this and was curious... Did you ever get closure to your question?
How do you know it's high?
Is there a reliable test to accurately measure estrogen levels? (I was under the impression that there isn't.)
Despite being thin (less body fat), I've heard that there a couple ways that the body continues to generate estrogen after an Oophorectomy. Others more familiar with the subject can certainly explain this better.
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My understanding of estrogen testing is that it can be tested by serum or urine, but there are some questions about accuracy. The body can continue to generate estrogen in those who have entered menopause naturally, or surgically, by converting androgens (produced by the adrenal gland) into to estrogen with the enzyme aromatase. Aromatase inhibitor drugs (Arimidex, Aromasin and Femara) interrupt this process by shutting down that enzyme and causing estrogen suppression. There is also some thought that remnants of the ovary left behind in a surgical procedure can continue to secrete estrogen, or that if you still have a uterus and have endometriosis, it can generate estrogen as well. Body fat, skin and muscle also produce some amount of estrogen.
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