Hysterectomy and oophyrectomy - Can't take estrogen therapy

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LW0919
LW0919 Member Posts: 196

My breast cancer was ER/PR + and I had a full hysterectomy, oophyrectomy and Fallopian tube removal back in mid May. I can't take estrogen replacement therapy because of my bc diagnosis but am starting to feel like I need to do something. I've started to realize how tired I am all of the time. I'm exhausted even with B12 injections. I can tell that I feel different than I used to. Not really moody, not really angry...just nothing! I don't believe I'm depressed, just no real drive left. I've always pushed to do more, be more, have more and now, I kind of don't really care. I don't really care what people think and I used to, that part isn't so bad but with all of this combined, I know that between the cancer treatments, surgeries and hysterectomy, I've changed. I should probably make an appointment with my oncologist or OBGYN but wanted to see if alone else has gone through or is going through the same thing and if so what you did or are currently doing in place of estrogen therapy. I've always found more helpful information here than I ever have in a Dr.'s office anyway!

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  • vlnrph
    vlnrph Member Posts: 1,632
    edited December 2014

    From your cute photo, I would say you are way too young to be so worn out! I assume you had a genetic mutation or another reason for that much surgery. Are you also performing a full time job, managing a household and/or chasing kids around? Plus, the holidays are upon us. These are just a few of the factors that can work together to multiply the stress we feel.

    All that being said, your primary care doctor will certainly want to make sure you're not anemic (perhaps that's the reason for the cyanocobalamin injections), show low vitamin D levels or have hypothyroidism. In addition, these short days & lack of natural light put many of us into a seasonal affective disorder. Perhaps a low dose of a mild anti-depressant medication might do the trick. Getting fresh air and exercise helps me. Hope you perk up soon...

  • LW0919
    LW0919 Member Posts: 196
    edited December 2014

    Thanks vlnrph! I'm 43 and had the hysterectomy and ovary/tube removal due to numerous fibroids and endometriosis that was causing hemhorraging (sp?). Which also caused anemia. However, I beleive I've recovered from the anemia though it might not be a bad idea to check that too. I do work between 50 - 60 hours a week and have 2 boys, 12 and 16. I was just wondering if it had something to do with the lack of hormones because I've always worked long hours and have managed the kids, house and the whole 9 yards. It's just getting harder to do. I don't miss the horrible bleeding but do believe I needed some of those hormones that I no longer have.

  • ED2012
    ED2012 Member Posts: 97
    edited December 2014

    I am so glad to find this thread and hope to see many more responses! I am 49 and just had to have a TAH/BSO on 12/1...so am technically in surgical menopause. It's only been two weeks and while I don't really feel much different now, reading about all the potential downstream effects are really scary. I did meet with my breast specialist to discuss options should I need them and was reassured by his common sense approach: he said a vaginal ring like estrace (BHRT) could be used without too much concern of it crossing into the bloodstream and that any that did...would be handled by the tamoxifen that I take. He also indicated that at some point, quality of life has to be considered, so told me not to suffer but to talk to him if/when the need arises. Boy, it seems there are major risk both with and without...so my line of thought at this point is that I might as well feel as decent as possible while I'm here. Of course, this is still early for me, but I hope some women who have walked this path before us might share their wisdom. Good luck to you and I hope you feel better soon! I work similar hours but my boys are now grown (27,25,23), but I well recall their younger years and think I remained chronically exhausted! I also have to take B12 injections.

  • LW0919
    LW0919 Member Posts: 196
    edited December 2014

    Hi ED2012. I too hope we get more responses! I made an appointment with my primary care Dr to discuss options. She had a last minute cancellation so I get to go in tomorrow. I'll come back and share what I find out. I'm hoping for a miracle. I want to feel like 43 again instead of 73!

  • vlnrph
    vlnrph Member Posts: 1,632
    edited December 2014

    I'm about 10-15 years older than you two and became menopausal with chemo so not exactly in your same situations but will suggest that being kind to yourself is a good idea at any age! That includes consuming a healthy diet and taking time for enjoyable activities.

    Try some different things, eliminate others which are not essential and know that you are certainly not alone. I even allowed myself to not put up a big Christmas tree which is unusual (in the past I have done two or three). Perhaps the doctor will have a few practical ideas also.

  • Anonymous
    Anonymous Member Posts: 1,376
    edited February 2015

    I just came across this thread. I'm somewhat similiar in age (43 at time of diagnosis...now just turned 48) Had a complete hysterectomy at 46 - due to an ovarian cancer scare...but turned up to be absolutely nothing. Go figure.

    What did you find out at your doctor appt in december?

    I've noticed that I have a lack of energy..or maybe even motivation? I just can't seem to get anything accomplished like I used to...and distract easily. I have recently not been eating as "clean" as I used to so am working on that and hoping that it turns things around. I also wonder about the cumulative effects of Tamoxifen? I guess I'll see when I get to ditch it...only one more year to go!!!! :)

  • ndgrrl
    ndgrrl Member Posts: 741
    edited February 2015


    I also just came across this thread. I am scheduled to have my ovaries out from an cancer scare on March 3. I am freaking at the thought of surgical menopause and hope others who have been down the road can provide some tips. My GYN said there are a few herbal things I can try, I was hoping I could take low dose HRT to sort of wean myself off of the hormones but I guess not. 

    I will be taken off of Tamoxifen a month after surgery so not sure what to think of that either as I will be put on one of the A1's. 

    Life- grrrrr

  • kamm
    kamm Member Posts: 140
    edited February 2015

    Everybody's different but I had mine out and had no problem. In fact I feel better than I have in my life. No ups and downs. Only mild hot flashes one to three times a day. Nothing compared to the flashes I had while on the AI and then Tamoxifen. Came off both due to SE's but that's another story. If your already on Tamoxifen you probably won't notice anything different.

  • Anonymous
    Anonymous Member Posts: 1,376
    edited February 2015

    ndgrrl, my recovery from the hysterectomy was a piece of cake...I was back to running at 6 weeks when I got the okay. Also, just FYI, I did stay on Tamoxifen. Since I was doing fine on it and have osteopenia... I didn't want to switch to the AI's. My MO was fine with that. Switching to AI's is not an absolute requirement. Obviously discuss with your MO.

  • jill47
    jill47 Member Posts: 351
    edited February 2015

    Hi ladies - I had a total hyster/ooph via davinci robotic due to recurring uterine polyps, fibroid's and excessive bleeding at 48. The surgery and recovery was nothing compared to bmx/recon however the long term effects are worse. Whatever estrogen I had left over depleted quickly, work performance suffered from fuzzy memory, confusion, developed bad headaches and eventually suffered major depression which I am still been treated for. I felt so bad I actually called by gyno/surgeon and begged to be put on HRT and he said no and that no doc will prescribe it to me b/c of bc. I asked how long I will feel this horrible and he said 10-15 years, that's when I lost it and had my first major depression. It's important to get a baseline bone density test (DEXA) a few months post ovary removals without estrogen replacement because estrogen is so vital to bone health. I had my baseline 3 months post surgery and results normal. 2nd DEXA a year later, I'm osteopenic right femoral neck (hip) and borderline left hip and spine. MO put me on Prolia without me asking. I am white, light weight, no estrogen and post menopausal at a young age and now osteopenic...high risk for osteoporosis. I had my first injection last month....we'll see how it works. Recently I learned I have high cholesterol, LDL and Total cholesterol increased 66 points in 7 months. This can happen to post menopausal women but gradually with natural menopause. I am concerned about my heart health since estrogen is good for the heart. My blood pressure has increased too, use to be 110/65-68 and is consistently now 125/85-87. Lastly I am on e-string b/c of vaginal atrophy and I still have to get annual paps even without a cervix b/c of b/c history. While estrogen worked against me with cancer and gynecological diseases....it has many great attributes which my body misses. Best to all who have to get their ovaries removed. Jill

  • Momine
    Momine Member Posts: 7,859
    edited February 2015

    Jill47, I am quite angry at your doc for telling you that you will feel horrible for 10-15 years. First of all, he has no way of knowing that, and secondly, that was not the case for me. I had the ooph/hyster, also at 48, then started femara, which makes the effect and estrogen deprivation worse. It was not fun for a while, but it slowly got better and now, 3 years after starting femara, I really feel pretty well most of the time.

    Exercise and a decent diet can help, btw, against many of the unpleasant side effects.

  • Momine
    Momine Member Posts: 7,859
    edited February 2015

    LW0919, the chemo can deplete your magnesium. A lot of docs are not alert to this, and magnesium deficiency can zap you. I started taking a small magnesium supplement a few months after finishing chemo and it helped quite a lot. There is no real downside to taking a bit of magnesium, as far as I know.

  • LW0919
    LW0919 Member Posts: 196
    edited February 2015

    After visiting with my primary care physician, it was decided that I would give Wellbutrin a try. I've been taking it for a couple of months now and can tell the mood is a little better and do have a bit more energy. I'm hoping once we get out of this winter funk and spring comes around it will be even better at that point. My onc just switched me from tamoxifen to anastrozole. I'm kind of Leary about what that will do when thrown into the mix but guess time will tell!

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