Oopherectomy after Mastectomy for Grade 3 Er-/Pr- breast cancer?

Hi Mimi,

I too had ER/PR- pure DCIS, and likeypur observation that it is important to be your own best advocate.

My GP had mentioned oopherectomy when we were brainstorming treatment/follow-up, but we didn't go ahead with it. I'm curious to see what you decide.

On another note, I'm curious what other tactical decisions you have made about prevention and monitoring post-mastectomy. Before my surgery, I hit all the boxes for high recurrence risk (large size, young age, high tumor grade, ER-) so my opinion is that one can't be too careful.

Hi ladies. I had a BMx on January 29 and am scheduled for my exchange June 2 and a hysterectomy and ovaries removed on July 1. I was diagnosed w DCIS in December, I have a strong family history of both breast and ovarian cancer. The past 2-3 years I've been dealing w heavy bleeding, large clots and irregular periods. My vs wanted me to have ovaries removed at 45 years old but w an iud and cryoablation that didn't work I have decided to have the hysyetectomy now. I am meeting w a mo June 4 discuss what I need to do after being thrown into surgical menopause. My cancer was ER and ZpR positive. Any one with any thoughts, advice, similar situation??

This is such an interesting thread.  Everyone posted valid points.  I had pure DCIS ER/PR negative. Did BMX in Dec and now have implants.  My Brca testing was done. For Brca1 it stated No Mutation Detected....but under that wording there was a variant with a number and it stated Favor Polymorphism.   For the Brca2 it came back No Mutation Detected.

Here's where it gets really strange.  My oncologist said I should see a Gyno Onc right away to have an oopherectomy preformed. I got so scared I got the appointment immediately.  This Gyno Onc tells me that I am Brca positive and even though it stated a Favor Polymorphism which means it isn't considered bad.  He said that you can't be half pregnant...this is the example he gives me. And that he himself is doing research and would want my ovaries and blood to help make a test that can test for ovarian cancers in the future. I thought that was pretty great.  I could be of help.  However, I started getting the sick feeling of more surgeries and by having an oopherectomy at 44 what it would do to my body.  After some more research on line, I finally called the geneticist from Myriad that does the Brca testing and she said I an NOT Brca positive and for him to want to remove my ovaries just based on my report is wrong.  Unless there were other underlying issues. But just going by my Brca report, I shouldn't. The geneticist was going to send someone to see this doctor to find out why he wasn't going by the guidelines for these reports.  And the scary thing is that this doctor had his nurse call me 3 times already to schedule surgery.  I never even agreed to it at the time of our first meeting. Way to jump the gun.  My brother said if I go missing, he knows where to look.  Invasion of the body snatchers.  LOL.  

And this doctor is Chief of Gyno Onc at the hospital (don't want to name names) and the Oncologist that referred me is part of the same hospital group. Just really scary and anyone else out there being told to get surgery, research and go for 2nd opinion.  

I am on birth control and see my Gyno every 6 months.  And once a year she does a Sono for the ovaries. We are being proactive and I think being er/pr negative, this is the best route for me.  She even said I am Brca negative.  

I'm just so confused.  But after reading this thread it helped me to understand that I wouldn't benefit from having them removed unless I had a family history of it.  Which that I can understand.

Just wanted to add my story to this as this all happened in the last 2 weeks.