Please Help/Read...needing advice ASAP
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Turkey Tail
http://www.ncbi.nlm.nih.gov/pubmed/21042722
An additional in vitro study showed that a medicinal mushroom blend that
included Coriolus inhibited cell proliferation and induced cell cycle
arrest at the G2/M phase in the invasive human breast cancer cell line
MDA-MB-231 (15).
DNA-microarray analysis indicated that the mushroom extract inhibited
the expression of cell cycle regulatory genes and suppressed metastatic
behavior through the inhibition of cell adhesion, cell migration, and
cell invasion . The inhibition of metastatic behavior was linked to the
suppression of urokinase plasminogen activator (uPA).LDN
http://www.sciencedaily.com/releases/2013/08/13081...
Human triple-negative breast cancer can be treated by modulation of the
opioid growth factor (OGF) - OGFr pathway. OGF suppresses cell growth by
20 percent within 24 hours in a receptor-mediated manner. Blockade of
OGFr using low dosages of the opioid antagonist naltrexone causes a
compensatory increase in OGF and results in 35 percent reductions in
cell number within 72 hours. These data demonstrate a novel biological
pathway for treatment of this deadly breast cancer.Bee Propolis
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC389861...
CAPE possesses a number of important biological activities, including
anti-bacterial, anti-viral, anti-fungal, anti-oxidant,
anti-inflammatory, and anti-cancer properties [10-16].
CAPE has been shown to be cytotoxic to many types of cancer cells,
including breast cancer cells, while having no such effects against
normal cells [17-26].
We have previously demonstrated that CAPE: (i) inhibits the growth of
MDA-MB-231 (MDA-231) triple-negative (ER−, PR−, Her2-) BC cells (TNBC),
and MCF-7 (ER+/PR+) BC cells both in vivo and in vitro;
(ii) inhibits growth of breast cancer stem cells; (iii) induces cell
cycle arrest and apoptosis and (iv) suppresses angiogenesis [25,26].NAC
http://bpccancerprotocol.wordpress.com/2013/07/08/...
The antioxidant
N-acetyl-cysteine (NAC) has been shown to be chemopreventive in clinical
studies, and in recent studies, has shown promise in preventing tumor
progression. Although the effects of NAC on tumorigenesis have been
associated with decreased angiogenesis, the mechanism of the
anti-angiogenic activity has not been determined. In the following
study, we describe a novel mechanism whereby NAC therapy blocks
MDA-MB-435 breast carcinoma cell proliferation and metastasis in an in v
iv o tumorigenic model. Athymic nude mice bearing MDA-MB-435 xenografts
were treated with systemic NAC daily for 8 weeks. NAC treatment
resulted in endothelial cell apoptosis and reduction of microvascular
density within the core of the tumor leading to significant tumor cell
apoptosis/necrosis. Angiostatin accumulated in tumors from NAC-treated
but not control animals. Additional studies using a vascular endothelial
growth factor-dependent chicken chorioallantoic membrane angiogenic
assay recapitulated NAC-induced endothelial apoptosis and coordinate
production of angiostatin, a potent endothelial apoptotic factor. In
vitro studies showed angiostatin was formed in endothelial cultures in a
vascular endothelial growth factor- and NAC-dependent manner, a process
that requires endothelial cell surface plasminogen activation. These
results suggest that systemic NAC therapy promotes anti-angiogenesis
through angiostatin production, resulting in endothelial apoptosis and
vascular collapse in the tumor.Curcumin
http://www.greenmedinfo.com/article/curcumin-induc...
In this study, we investigated the effects of curcumin on
triple-negative breast cancer cells and the possible molecular
mechanisms. The MDA-MB-231 TNBC cells were treated with curcumin, the
growth inhibition ratio of the cells was measured by MTT assay,
apoptosis was detected by flow cytometryand the expression levels of
extracellular regulated protein kinase (ERK1/2), pERK1/2, EGFR and pEGFR
were detected by western blotting. After treatment with different
concentrations of curcumin, the growth inhibition rates of the
MDA-MB-231 breast cancer cells of the 30 µmol/ml curcumin-treatedgroup
were significantly different from those of the other groups. The level
of apoptosis of the curcumin‑treated group (26.34%) was significantly
different from that of the control group (2.76%). The expression levels
of pERK1/2 and pEGFR in the curcumin-treated group were significantly
decreasedcompared with those of the control group. These results
indicate that curcumin is able to inhibit the proliferation of TNBC
cells. Inhibition of the EGFR signaling pathway is the likely underlying
molecular mechanism.Rath protocol
http://www.drrathresearch.org/research/publication...
Current treatments are generally ineffective once breast cancer has
metastasized; median survival is reduced to 2-3 years. Previous research
studies demonstrating potent synergistic antitumor activity of lysine,
proline, ascorbic acid and epigallocatechin gallate prompted us to
investigate the in vivo inhibitory effect of a nutrient mixture
containing lysine, proline, arginine, ascorbic acid, and
epigallocatechin gallate (NM) on the growth of human cancer xenografts
in female athymic nude mice. 5-6 week old female mice were inoculated
with 3x106 breast cancer cells MDA-MB-231. After injection, the mice
were randomly divided into two groups A and B; group A was fed a regular
diet and group B with the regular diet supplemented with 0.5% of the
nutrient mixture. Four weeks later, the mice were sacrificed, and their
tumors were excised, weighed, and processed for histology. We also
tested the effect of NM in vitro on estrogen-receptor positive (ER+)
MCF-7 and estrogen-receptor negative (ER-) MDA-MB-231 breast cancer cell
lines by measuring: cell proliferation by MTT assay, expression of MMPs
by gelatinase zymography, invasion through Matrigel, and VEGF by ELISA.
MCF-7 cells were also treated with estradiol to study enhanced invasion
and expression of MMPs and VEGF. Results showed that NM inhibited the
growth and reduced the size of tumors in female nude mice by 27%.
Furthermore, histological evaluation revealed increased mitotic index,
MMP-9 and VEGF secretion and PAS material (mucin) in the control group
tissues. In vitro studies showed NM inhibited MDA-MB-231 cell growth by
34% at 500 µg/ml and MCF-7 cell growth by 18% at 1000 µg/ml. Invasion of
MDA-MB-231 through Matrigel was inhibited by 50%, 60% and 95% by 10, 50
and 100 µg/ml of NM, respectively. The results of this study
demonstrated that the nutrient mixture, tested significantly suppressed
tumor growth of breast cancer cells in female athymic nude mice and
significantly inhibited MMP expression, angiogenesis, and invasion in
breast cancer cells, in vitro, offering promise for therapeutic use in
the treatment of breast cancer. -
Just to add on to lightandwind's post on PSK.
PSK is generally linked to HLA antigen for best results.
Link below is research solely on PSK rather than a combination of mushrooms. The HLA B40 antigen is crucial as seen here.
There is also a clinical trial for PSK and as I've read in another forum, you must test positive for HLA-A2.
FYI, in case anyone is interested.
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thenewme, I looked at "If Cancer Treatments Work in a Mouse, it Must Work in Humans, Right?" What was the point of that? We should ignore studies in mice, because they don't adequately reflect what works in humans? Then why are thousands of researchers using mice for test subjects? I have to say, I try to stay away from sites as openly biased as the one you linked to. It says at the top: blogging against alternative cancer treatments. As if that's going to be a fair and balanced source of information! That's the beautiful thing about science, it's meant to take the bias out.
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I tried to hold my fingers but what's the point coming here to tell us the negative aspects of alternative?
I can read and I am capable to understand. And I want ppl to respect our choices. I didn't go to the conventional forum to broadcast medical conspiracy or comments as such.
Why coming here to read something you are so against to? Go knock yourself out with chemo and radiation. Nobody is stopping you.
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"Hope is real" - so true...I need hope.
I'm knocking myself out with both conventional and alternative treatments
I'd be lost without both threads - the value of both bco areas are "priceless" to me. I chose what information I receive and what I don't.
By the way, my relative's brother was dx with mets from prostate cancer and docs gave him 6 months to live - even though he had several surgeries, chemo, radiation. He completely changed his lifestyle - diet, supplements to include several mushroom extract(s) - he is in his 8th year of living cancer free.
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Aae2014 - if you are interested in locating a naturopathic in addition to your bc team, here's a link:
http://www.naturopathic.org/AF_MemberDirectory.asp?version=1
This is only my opinion since I'm not a doctor - I chose a naturopthic who practices integrative medicine - I have a team of naturopathics I'm working with currently along with my conventional bc docs.
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light: I've known about that russian writer & artimesia for so many years & I forgot why I didn't concider it before (It hasn't gotten here by the way) if fennel juiced put me in this fix because of its strong estrogenic properties, artemesia is also liquorice tasting so it perhaps is estrogenic as well.
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Peacestrength, I was at the grocery store the other day and a woman working there had offered me a sample of something that came from a can, and I asked her if it was a BPA free can, and she asked me why, and I explained about it's negative effect on BC and she told me that her mother had been diagnosed w/ inoperable lung cancer, had failed chemos, and was given an expiration date. She said that she stopped treatment and started taking barley green powder and her cancer is now gone and she is still alive 3 years later. Now that seemed far fetched to me, but she did not strike me as a liar.
Abigal, I don't know but here's a link to a study on artemisinin and breast cancer.
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Aaae2014, I'm thinking of you and hoping your treatment is going well. Please let us know how you're doing when you have a chance!
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Just an interesting footnote - I was vacationing in South Florida last week and my friend who happens to be Cuban, took me to a small open air Latin farmers market. I came across 2 tables of several varieties of large fat leaves, one smooth type and one spiky. It was Bittermelon! And the folks were buying tons of it. It was from a few different South American countries. I remember Honduras for the spiky one. So it's obviously not just part of the Asian culture diet but various Latin cultures as well.
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I am also stage IV triple negative. I was diagnosed at stage IV may 2013. My cancer has spread to my chest, bone and spine. I have changed my diet... Mainly veggies and yes sprouts too. Eating this way has made me feel better! I decided to take summer off if chemo and enjoy the family. I had a double mastectomy about 2 weeks which was unexpected, but necessary. So now I am recovering thinking what natural regiment I can find... So I am eating raw foods, taking high doses if vitamin D and C and taking some natural supplements. Good luck and let me know if you come up with anything else to try....
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Here's some studies on sea cucumber and breast cancer metastasis/apotosis. I collected some of this infor from another thread on another forum.
http://www.ncbi.nlm.nih.gov/pubmed/21761157 http://www.ncbi.nlm.nih.gov/pubmed/21741966
There are clinical trials going right now for sea cucumber and cancer
but they are actually for myeloma not bc, but here is the info on the
trialshttp://www.clinicaltrials.gov/ct2/show/NCT01096810?term=sea+cucumber&rank=
There are some testimonials for success treating breast cancer w/ sea cucumber extract on this website. www.thecancerhasgone.com
Here are some studies on sea cucumber immuno-modulating effects, tumor
suppression, lipid metabolism ( cholesterol metabolism is now connected
to breast cancer growth-- make sure your doc is monitoring cholesterol
levels).http://science.naturalnews.com/sea_cucumber.html
http://naturalsociety.com/sea-cucumber-shrinks-cancer-cells-95-percent/#ixzz2jwluwCJK
And here's link to a PDF on sea cucumber effect on various cancers
http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=16&ved=0CFgQFjAFOAo&url=http%3A
Frondoside A inhibits breast cancer ... [Breast Cancer Res Treat. 2012] - PubMed - NCBI
Frondoside A, derived from the sea cucumber Cucumaria frondosa has
demonstrable anticancer activity in several models, however, the ability
of Frondoside A to affect tumor metastasis has not been reported.Frondoside A inhibits breast cancer ... [Breast Cancer Res Treat. 2012] - PubMed - NCBI
www.ncbi.nlm.nih.gov
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To cheery, the missing component, is emotional. Sometimes a person can do everything right, but emotions can change cells. Look up Dr. Hamer in Germany, he might be in spain now. He had to go underground, because he was curing terminally patient's thru emotional healing 97% success rate. He would scan their brains, and know exactly where the cancer was, and where it was healing by the lesions in the brain. Fascinating stuff. Emotions are HUGE!! With cancer. As well as phase 2 detox. Its called the methylation process. Most cancer patients aren't doing it. So, toxins can't get out. Research it , very interesting. Wish you the best.
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Does anyone have experience with turkey tail mushrooms and their effectiveness in fighting and preventing cancer?
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There is a video on youtube about it...can't find it now or unavailable...but here is an article.
http://medicinalmushroominfo.com/turkey-tail-mushroom-cancer-paul-stamets/
Turns out Dr. Paul Stamets mother was dx with stage IV bc and he had her use them, I believe in supplement form.
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I used to deal with a rep from a vitamin company, who used it in conjunction with chemo. Put her in remission. Don't know what did what. I have read the research, it is qquite compelling.
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I think Ryker Hamer is supposed to be in Norway now. I have actually read a lot about him and was not overly impressed. Yes, emotions are important but if one is not "cured" then it becomes a kind of blame the patient thing. Dealing with emotions and trauma are important for living as happy a life as possible (certainly makes living with bc easier) but, IMO, have little to no influence on the course of the disease.
However, here is what disgusted me about Herr Hamer (yes, it from Wikipedia but you can find the same info from other sources if you don't trust Wikipedia )
" Hamer purports that his method is a "Germanic" alternative to mainstream clinical medicine which he claims is part of aJewish conspiracy to decimate non-Jews. In this Hamer follows the antisemitic "Neue Deutsche Heilkunde" propagated inNazi Germany. More precisely he asserts that chemotherapy and morphine are used to "mass murder" the western civilisation, while such treatment is not used in Israel where nearly no people die of cancer, according to him.[8][9][15] He promotes the idea that most oncologists in Germany are Jewish and that "no jew is treated with chemotherapy in Germany". According to him hypodermic needles are used during chemotherapy to implant "chips" containing "chambers of poison" that can be activated by satellite to specifically kill patients.[16] He proposes that the swine flu vaccination campaign of 2009 has also been used to mark people with those "chips" and denies the existence of HIV.[17] Hamer also believes that the denial of recognition of his theories and the revocation of his practitioner's licence is due to a Jewish conspiracy.[15]
In 2008, Hamer presented a document where one "Chief Rabbi" "Esra" Iwan Götz confirms the existence of a conspiracy among Jewish oncologists to use the "torture" of chemotherapy on all non-Jewish patients, while Jewish patients were to receive the "correct" treatment of GNM. Iwan Götz is a German holocaust denialist active in the German Reich revivalismscene who has been repeatedly convicted by German courts on counts of holocaust denial,[18] fraud, defamation, misuse of academic titles (the title "Chief Rabbi" is not legally protected in Germany), falsification of documents, among others.[19]"
I can't even put in to words how revolting I find this.
Caryn
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Wow! Lets not focus on the positive. There will always be a negative or an excuse for you. Think its time to leave us alone. If people want to research Dr. Hamer they can do it and get the whole story, and the good he has accomplished. I think its ironic u find the piece about how chem and morphine was used to kill people. I just recently found out a lot about how morphine causes cancer. I always look for the positives. I'm not in denial. But you will always be able to find the negative if that's what you are looming for. Why do you think people develop multiple personality disorders? I know a couple people who have, due to childhood trauma. According to their Dr.s.
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inga,
This is the complimentary forum and as such invites those who combine conventional and complimentary tx to participate. That would be me, so there is no "us" to leave alone. As for focusing on the negative, sorry but I just can't get behind people who blame Jews(or any other group of people) for the world's woes. For the record chemo is definitely used in Israel. Jews do not want to kill off non-Jews. Chemo and morphine may kill people, but it's not a Jewish conspiracy. His kind of rabid anti-semitism is abhorrent.
"There will always be a negative or an excuse for you" Nope, I just ask lots of questions and don't accept things because someone said so or told me a story. That's how I think outside of the box and yes, I question my conventional docs just as much and just as deeply. I must laugh since I am often thought of, by those who know me, as an extraordinarily positive person. Questioning deeply is not a sign of negativity.
Traumas and schizophrenia? I confess to knowing little about that,but I was referring to bc and trauma, not other diseases.
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It sounds like Dr. Hamer is the one with schizophrenia. I am with Caryn on this one. He is abhorrent, and I am absolutely certain that his 97% cure rate is complete bull excrement. I looked into it when I first came across him.
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Time to bring up David Servan-Schreiber and his Anti -Cancer book once again. Inga have you looked at it? Shreiber places a lot of emphasis on the importance of awareness and the mind body connection.
I read the first edition of the book (library copy) during the time my husband was undergoing treatment for a stage IV cancer in 2010. It helped me a lot. When the second edition came out the first edition copies were heavily discounted and I was considering getting one but thought to take a look at the introduction to the second edition first instead. I bought the new book - full price.
<quoting from introduction page 2, typos are mine>
If there is one single, clear, and emphatic message I'd like to send with this revised edition, it is that we must pay close attention to the mind-body connection, especially the negative impact of prolonged feelings of helplessness and despair. When left unattended, these feelings--not the stresses of life themselves--contribute to the inflammatory processes that can help cancer grow. There are truly effective and simple methods for taming those feelings, experiencing life on a more satisfying level, and reducing inflammation at the same time.......To address this, I've, I've completely revised chapter 9, "The Anticancer Mind,"....
<end quote, and sending before I lose it>
Kathy
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I came across this story a week ago and I wanted to post the link. I was apprehensive because I wonder if the story is truthful and I have no way of determining if it is. Since it is definitely on topic, here it is (I have emailed this woman and although, I read stage III, she stated stage IV in her email).
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Kathy044, no I haven't read that book. Sounds very interesting. I have read so much about this in the past. To be quite frank, I limit my reading about cancer now. I don't want it to become my identity. Like it has for so many people. I try to fill my life with other things. But that book, I might have to look into. Thabks
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