Great study from Pubmed on curcumin!

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jojo68
jojo68 Member Posts: 881
edited June 2014 in Complementary and Holistic Medicine and Treatment

http://www.ncbi.nlm.nih.gov/m/pubmed/24371229/#

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  • Momine
    Momine Member Posts: 7,859
    edited January 2014

    Cool! Thanks for posting.

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  • warrior70
    warrior70 Member Posts: 144
    edited January 2014

    I just got some circumin capsules this weekend.  So glad to see this!!!!

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  • cp418
    cp418 Member Posts: 7,079
    edited January 2014

    Thanks for posting this article!!

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  • sandilee
    sandilee Member Posts: 1,843
    edited January 2014

    how much curcumin is a good daily dose?

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  • Fallleaves
    Fallleaves Member Posts: 806
    edited January 2014

    Nice to see another article showing the benefits of curcumin. I wonder how much has an effect, though? I've been taking 1 g in the morning and 1 g at night since last summer. Hopefully it's been knocking out some BC stem cells (and stem-like cells). Eh well, can't hurt anyway, since I'm not taking any drugs it can interfere with ( and I never heard of anyone O.D' ing on tumeric).

    Thanks for sharing.

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  • Scandophile
    Scandophile Member Posts: 71
    edited January 2014

    Great re-inforcement of other studies, thanks for posting!  I am on 3g per day now as part of my supplement regimen. I will drop down to 1.5g/day once I am in NED status.

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  • pip57
    pip57 Member Posts: 12,401
    edited January 2014

    I take it by capsule twice daily and use it on my food at dinner most every night.  It is a blood thinner so you have to be careful if you have any other conditions in which that would be a factor.  

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  • LizzieK
    LizzieK Member Posts: 67
    edited January 2014

    This is interesting but as a biologist I have to tell you what happens in a petri dish doesn't always translate to what happens when you eat the compound.  It may not get absorbed by your digestive system such that it gets into your blood and gets to the tumor cells.   Probably no harm in taking it but I'd like to see some clinical studies on people eating it to see if it works the same way.

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  • Maggs09
    Maggs09 Member Posts: 193
    edited January 2014

    I hate to sound negative but I totally agree with LizzieK. Based on in vitro studies I also started turmeric capsules, small dose (550mg daily) since I'm on tamoxifen, and already knew that it can slightly inhibit the enzyme necessary to convert tamoxifen into endoxifen, (active form). 

    I had my endoxifen levels checked before starting curcumin supplement and then again, in just over a month into it. In my case turmeric significantly lowered absorption and metabolism of tamoxifen, therefore endoxifen in my blood dropped by half. I was told by my dr to stop and we retested again in 3 months. My endoxifen went back to the level from before turmeric. Turmeric was the only thing added and then removed from my diet. Im very diligent with all my meds and vit, and I record everything. I don't over supplement, just vit D 1000, liquid calcium/magnesium/vit D combination to help bones, fish oil, vit C 500, metformin. I don't know if it was just that specific brand of turmeric capsules (BELL) or combination of everything else, or just me...

    So LizzieK has a point that what works in a petri dish, maybe not necessarily have the same outcome in a human body, where is combined with many other, very individual elements.

    I don't doubt that turmeric has an amazing properties, but an extra caution should be exercised when taken in combination with other medication. 

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  • jojo68
    jojo68 Member Posts: 881
    edited January 2014

    Interesting points about curcumin!  Will have to investigate further....This journey can be so confusing to navigate at times. sigh

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  • Anonymous
    Anonymous Member Posts: 1,376
    edited January 2014

    My naturopath told me about this shortly after dx. I've been taking it (except during chemo, rads) ever since.  Like all tx, it probably doesn't work for everyone, but I'm giving myself every opp to beat the beast, so....

    Claire in AZ

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  • althea
    althea Member Posts: 1,595
    edited January 2014

    I started giving my mom turmeric supplements after reading how it helps with brain plaque.  It hasn't helped a bit in improving her cognition.  At 86, she no doubt has absorption issues for anything entering her digestive tract.  

    Does anyone know of other contraindications for turmeric as they relate to prescriptions? 

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  • jojo68
    jojo68 Member Posts: 881
    edited January 2014

    I think it contraindicates with NAC, not sure about RX though

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  • gemini4
    gemini4 Member Posts: 532
    edited January 2014

    JoJo, what is NAC?  

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  • jojo68
    jojo68 Member Posts: 881
    edited January 2014

    http://www.invitehealth.com/nac-600-mg/allergies-respiratory-health-inflammation/


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  • abigail48
    abigail48 Member Posts: 1,699
    edited January 2014

    my mother also said all things in moderation, I think though that isn't sensible either.  some things need lots, some a bit & some none

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  • pip57
    pip57 Member Posts: 12,401
    edited January 2014

    Turmeric also acts as a blood thinner so be cautious if your mom is already on prescribed thinners.

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  • althea
    althea Member Posts: 1,595
    edited January 2014

    My mom does take a blood thinner.  Her levels are consistently within range, before the turmeric and during. 

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  • Lily55
    Lily55 Member Posts: 3,534
    edited January 2014

    n acetyl cysteine

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