Should hyperplasia be stated as ductal or lobular. E-cadherin...

I'm not sure if you are planning on removing a lump or area of your breast or are planning on having your breast removed.  Unless you have an extensive family history of breast/ovarian cancer (such as your mother died of breast or ovarian cancer that metastasized to her brain), or you have other big risk factors for breast cancer such as radiation *treatment* for lymphoma, I'd be quite surprised if a surgeon in the US would do a mastectomy on a woman with hyperplasia only.  Brain cancer (where the cancer starts in the brain) in a parent is not a significant risk factor for breast cancer.

glorianna, I agree with leaf.   From what you've said in all your posts, your personal health history and your family health history does not seem to suggest that you are particularly high risk for breast cancer.

What you have to keep in mind is that 1 out of every 2 men and 1 out of every 3 women will develop cancer during their lifetime.  So the fact that you have some cancer in your family - your mother's brain cancer - does not mean that you are any higher risk than the average person. And as leaf said, brain cancer in a parent is not a risk factor for breast cancer.

You mentioned in a post yesterday that you've had "different pathology results from colonoscopy"; you've also mentioned that you've had an ovarian tumor (but you did not incicate that it was cancer), and that you have dense breasts (level 3 density) and hyperplasia.  So it sounds as though you've had a number of health issues that are causing you to want to do something to reduce your risk. That's understandable.  But here's the thing.  It doesn't sound as though these various health issues are related to each other and it doesn't appear that any of these problems have increased your breast cancer risk by any significant amount.  As I mentioned in another post, level 3 density is actually pretty normal for someone who is premenopausal.  And usual hyperplasia does not increase risk.

The simple fact is that as we age, many of us encounter the sort of problems you've been having.  I've had breast cancer, I have a family that's full of cancer (all but one person in my immediate family has had cancer and there are many more cases of cancer when you move out to my second degree relatives), and I've had other (non-breast) pre-cancerous lesions and various other problems.  Yet all in all, I'm not considered to be particularly high risk.  That's because it's normal to have these sorts of problems. It's a crappy part of getting older.

I appreciate that you want to be proactive, how is removing your breasts being proactive when you aren't particularly high risk to get breast cancer?  Removing your breasts probably wouldn't do much to change your overall health or risk level.

Now, as for the mass behind your nipple, has this been biopsied, and if so, what has the result of the biopsy been? Is that the biopsy that uncovered the hyperplasia? Since you are concerned about this mass, have you talked to any surgeon about  removing this mass?  If the mass is removed and something more serious than hyperplasia is found, that might change the situation and your options.

glorianna, it's just not true that every women with breast cancer would opt for a PBMX, if given a 2nd chance.

I had breast cancer.  I had a MX - not by choice but because I had to have it.  I opted for a single MX, not a BMX.  And if I could do it again and if I didn't need to have the MX, I would gladly have a lumpectomy + rads.

Yes, there are some women who've been diagnosed who wish that they could have had a PBMX first.  And there are some women who've had a lumpectomy who in hindsight might have chosen a MX or BMX.  But there are also many women who've had breast cancer who are happy with their choice to have a lumpectomy, and there are some who've had a BMX who in hindsight wish that they hadn't.

As I mentioned in another reply to you, a MX is much more complicated that you may think and for some women, it comes with lingering or lifelong side effects.  Anyone who has a MX will be affected, in one way or another, for the rest of her life.  It is not a decision to be taken lightly, nor is it something to jump into in the mistaken belief that it will eliminate all of one's risk without any implications or side effects or after effects.