Don't understand ca27.29

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30DEBBIE
30DEBBIE Member Posts: 105

We I was cancer free the marker was between 10-11. Since April 2011 my marker' go down with treatment to in the 30's and my cea goes very very low . When the drugs didn't work which was from the trial, the c27.29 went up and the drugs stoped working . So now I am on new drugs since December 2011. M y makers were going down for months and now they are starting to rise in the 30's geting closer to the higher end of the normal range. Since my history shows marker increase means growth why would I not been scanned yet? My last scan was January 2012. I live by logic but oncologists don't? Isn't it better to scan now see what Is going on with my disease , any progression, anything new and change my med's to catch change earlly if that is the case? Why wait for growth or sunstantial. I understand my oncologists philiosopy which is basically the same as other oncologists. I read. But I don't get it, As I feel my history speaks for its self. Why???? What is the basis of there philosophy. ? Each person is unique so why base it on scientific statistics? Am I so wrong.? Not understanding. I have a call into the dr. To help me understand scientific statistic vs logical of an individual body

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  • HLB
    HLB Member Posts: 1,760
    edited July 2012

    Hi, I see its been a while and no one replied but I am new. I don't really understand it either. I was told its not a totally reliable test and what the look for is trends rather than a single jump in the number. I was told that 38 or less is normal and not to worry. So does that mean 37 is just as good as 11??? I doubt it! Its frustrating to be treated with standard of care when we all have different situations.

  • kathleen1966
    kathleen1966 Member Posts: 793
    edited July 2012

    I'm glad you bumped your post by answering after it!  Now it will get noticed! Here I am so that's proof!  I think you are right. Tumor markers seem to work for you, although they are very unreliable for some.  I have only had the 15.3 done.  It was 22 in the beginning, then went down to 18, then up to 19, then 20.  Now it is 22.  That really is not a significant change and is still in the normal range.  I would say, they are of little use to me probably. They have always been around the same before, during and after treatment.  But you have seen your markers fluctuate when the treatment hasn't worked.  So I would mention your thinking to your oncologist and asks for scans. I see now that you are stage IV.  I hope you post this in the stage IV forum as well. You will get much help, support and good answers over there.-sorry I see that someone finally just answered and you didn't bump your own post.  I don't know how I messed that up!

  • 30DEBBIE
    30DEBBIE Member Posts: 105
    edited July 2012

    Hi uglyindian, I agree with all you said. I was rescanned and markers going up did not relate to tumor growth So now it's more confusing. I guess not be being a doctor is why. They go by trends and our symptoms. Thanks for responding. Have a nice weekend !

  • diana50
    diana50 Member Posts: 2,134
    edited August 2012

    if your cancer returns, it has to be "measureable"  or large enough to see on a PET scan, CT or MRI.  somes times if you are scanned too prematurely....and if there is active cancer going on but not large enough to be seen on scan.. you think you are fine when you may not be.  often times with elevation of tumor markers...depending on the number...we are talking about OVER 38....like doubled or tripled....then you may get a scan...or another retest in a few months to see what it is doing. remember; the tumor marker test looks at cancer proteins in the blood.  (that is why during chemo sometimes your marker will elevate because the chemo is moving the cancer cells around and killing them) 

    very important that you can talk to your oncologist about your concerns and questions.  hang in there(

  • Kindergarten
    Kindergarten Member Posts: 4,869
    edited August 2012

    Hi, there!!! I am glad I saw this post. I am almost 8 years out and my last 3 oncs(hubby was transferred alot, so new oncs each state) never used the CA2729, said they don't use it for non Stage 4 patients. I have a new onc in CA and she wanted a baseline. Mine came back at 67, and she wants a repeat on August 20th. I am little worried and not sure what it means. Any opinions!!! I feel really good!!!!

  • Lauriesh
    Lauriesh Member Posts: 692
    edited August 2012

    It is hard to say what the 67 means for you because you have nothing to compare it to. For me, when I was early stage, my ca 27/29 ranged between 9 & 11. When I was diagnosed with liver mets, mine was at 50. That was high for me.

    Hopefully the next time you have it, it will have dropped more into the normal range. If not, hopefully you will have scans to rule out anything.



    Laurie

  • Kindergarten
    Kindergarten Member Posts: 4,869
    edited August 2012

    Thank you Laurie!!! I so appreciate your reply. How are you doing?

  • Lauriesh
    Lauriesh Member Posts: 692
    edited August 2012

    I am doing well.  I have been NED for a year and a half and taking a break from Herceptin & tykerb for the summer since my last ca 27/29  was 9.8.

    Let us know what your tumor marker is at the end of the month.

    good luck

    Laurie  

  • nowords
    nowords Member Posts: 423
    edited August 2012

    My Oncolgist said that infections, bowel issues, and other off par health issues unrelated to cancer can cause small elevations ....

  • Kindergarten
    Kindergarten Member Posts: 4,869
    edited August 2012

    Dear Laurie, that is wonderful, you are doing great!!!! I will definitely let you know. Thanks to you as well, nowords, your words made me feel better as well. Blessings and hugs, Kathy

  • netty46
    netty46 Member Posts: 296
    edited October 2012

    Diana 50

    I had pet scan, mri of breast, mri of comeplet spine, bone scan, cat scan of chest all with contrast and all clear just in july.  now tumors are slightly up.  im on chemo now.  in fact chemo has made all residual from breast dissapear.  now I ask what is the deal with the markers.  this is a nightmare.

  • bluepearl
    bluepearl Member Posts: 961
    edited October 2012

    Chemo can make markers rise. A lot of things do. And one can have cancer and perfect tumor marker scores. Oddly, it doesn't seem to matter how much mets you have, the treatment is the same so they often go by how you feel rather than markers......and yes, trends would give a batter idea of how your markers respond (tumor markers are in everyone, not just cancer patients and they do not measure cancer cells). There's a new blood test coming up that can detect cancer at its earliest stage.

  • 30DEBBIE
    30DEBBIE Member Posts: 105
    edited October 2012

    Thanks for the response. December will be one year I am on chemo my so now I wait for the cancer to become immune to the chemo. Have a nice weekend

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