BC Survival Rises up to 58% With Cruciferous Vegetable Intake

What I would like to know is does it have to be oral food or would taking DIM suppliments do the same thing? Another question I would have is could we take the DIM with an AL to reduce our risk even more.

Interesting I have heard that before and realized altho I ate cruc veggies, I did not eat that many,ate far more potatoes like the general US public and far more junk than veggies & fruits.

Also, I am allergic to the Arimi the MO gave me so he took me off and didnt want to give me another type medicine or Tamox. I then decided to take Grapeseed extract which is an Aromatase inhibitor but cant find any trials or news on how effective it might be??

Gotta go,the cabbage is calling me..

My problem is:  I already ate 1+lb of cabbage brocoli/day before dx.   and exercise, blah blah, no family history blah blah and I still have grade 3 stage II tumor.    So sorry to rain on the cabbage parade.  BC is still a crapshot 

jenro that's true it by no means is it a cure all. I'm not sure I ate a pound every day, but it sure was close. I love all those vegetables in any form I can get them. I will say though for a few months before the BC was found there were quite a few vegetables I had always loved that I found were not appealing in fact tasted quite bad to me. The cabbage brocc family being one, but also mushrooms which I have always loved plus asparagus. Now I'm not saying it was the cancer causing the changes in me, but it is something I will keep an eye out for in the future.

"a dose-dependent impact on the hazard rate for overall mortality, breast cancer-specific mortality, and non-breast cancer mortality. The magnitude of the risk reduction ranged as high as 58%."

Sounds encouraging. I personally don't know, but I would almost think DIM might be better since it would be difficult at best to eat a large dose of cruciferous vegs. daily.  Dim would make the larger dose much easier.

JMO

Joy, I saw that, you beat me to it 

I'm moving over here, was diverting the topic on the other thread...

I am more and more convinced that I am doing the right thing in replacing Tamox and AI with DIM. Purple, you're absolutely right.  There's no way one could eat enough brassica in one day to match a DIM capsule.  I take 4 a day.

Copying the results of a small trial :

"Postmenopausal women ages 50-70 from Marin County, with a history of early stage breast cancer, were screened for interest and eligibility in this study on the effect of absorbable DIM (BioResponse-DIM®) supplements on urinary estrogen metabolites. We recruited 23 eligible postmenopausal women from Marin County, California with a history of early stage breast cancer (Stages 0-2) and randomly assigned them to two groups in a double blind fashion. The treatment group received daily absorbable DIM (108mg/day of DIM) supplements for 30 days and the control group received a placebo capsule daily for 30 days.

We tested 2-OHE1, 16 alpha-OHE1, DIM, estrone (E1), estradiol (E2), and estriol (E3), 6beta-hydroxycortisol, and cortisol in the "first morning" urine sample of controls and DIM treated subjects before intervention and 31 days after intervention. Nineteen women completed the study according to protocol, making a total of 10 in the treatment group and nine in the placebo group.

DIM treated subjects showed a significant increase in 2-OHE1, DIM and cortisol and the increase in the 2-OHE1/16alpha-OHE1 ratio approached significance (indicative of chemoprevention). The 6beta-hydroxycortisol/cortisol ratio is lowered indicating a lower total production of 4-hydroxyestrone and 16alpha-hydroxyestrone (potential carcinogens).

All of these findings could be associated with a reduced risk-status for breast cancer. In cell culture, DIM causes apoptosis leading to death of breast cancer cells and prevents endometrial cancer cell growth"

http://cbcrp.org.127.seekdotnet.com/research/PageGrant.asp?grant_id=2064 

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A more recent study (2011):

"In conclusion, findings presented in this study demonstrate pre-clinical proof of efficacy of DIM in breast cancer cell lines; thus DIM should be evaluated further as a potential agent for estrogen-dependent and estrogen-negative breast cancer"

http://202.204.209.200/upload/20120109030120.pdf

Kuddos to the researchers for acknowledging the following:

"Despite major advances in early detection and adjuvant therapy, advanced breast cancer remains a major clinical problem. Therefore, there is an urgent need for new therapeutic approaches. The perceived health benefits of micronutrient supplements and phytochemicals have generated considerable interest in recent years because of their potential roles in cancer prevention and treatment"

________ 

Coraleliz, that's what I said to myself too, but then the thought occurred to me that maybe my healthy eating kept my tumour from progressing further.  Food for thought

YW  Layla and good luck to you!

Scientists believe BC is at least 10 diseases. So, even if you ate 2lbs of veggies before your BC dx, there are still 9 other things that could have caused your BC.



I noticed most in the thread were ER+ so yes broccoli lessened the amount of estrogen but obviously your body was producing more than the broccoli could handle. This also does not address your immune system, vit d levels, glucose levels, stress levels, weight, fat, melatonin, and a host of other things.

ThatGirl, exactly !!

I'm not gonna post all the studies I have on I3C/DIM anti cancer properties because I would crash BCO computers, succintly, this says it all:

Indole-3-carbinol - anti-cancer chemical. Cruciferae, particularly the genus Brassica (cabbage, radishes, cauliflower, broccoli, russels sprouts, and daikon) produce Indole-3-carbinol. 

Under acidic conditions, Indole-3-carbinol is converted to a series of oligomeric products
(among which 3,3'-diindolylmethane is a major component) thought to be responsible for
its biological effects in vivo. In vitro, Indole-3-carbinol has been shown to suppress the
proliferation of various tumor cells including breast cancer, prostate cancer, endometrial
cancer, colon cancer, and leukemic cells; induce G1/S arrest of the cell cycle, and induce
apoptosis

In vivo, researchers also found Indole-3-carbinol to be a potent chemopreventive agent
for hormonal-dependent cancers such as breast and cervical cancer. These benefits are
mediated through its ability to induce apoptosis, inhibit DNA-carcinogen adduct
formation, and suppress free-radical production, stimulate 2-hydroxylation of estradiol,
inhibit invasion and angiogenesis 

Cruciferous veges also contain sulforaphane, an isothiocyanate - another anti-cancer chemical, indoles, vitamins, anti-oxydants, polyphenols, etc. etc. etc. 

Plus, the veges need to be steamed a specific length of time to release all the goodies and one needs optimum digestive function 

YOU ARE NOT WHAT YOU EAT BUT WHAT YOU ABSORB