Would a KETONE Diet Kill Cancer?

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  • cheery
    cheery Member Posts: 311
    edited April 2012

    Once again, much thanks, Joy!

    Wow, that 30-year-old mummy sounds creepy..Surprised 

  • luv_gardening
    luv_gardening Member Posts: 1,393
    edited April 2012

    Further research shows that the longevity claims in Okinawa may be exaggerated and can't be verified due to the different method of recording births.  It's thought that they still hold the record as the differences aren't likely to be that large. The PDF is long and difficult to follow but I include the link for the record.

    Exceptional longevity in Okinawa: A plea for in-depth validation
    Michel Poulain   2011

  • purple32
    purple32 Member Posts: 3,188
    edited April 2012

    The question of the post subject line is :

    " Would a ketone diet kill cancer ?"

    The answer is quite obvious- If it did , would any of us HAVE cancer ?

    Many people have gone on these diets and have not been spared.

    You are certainly entitled to your opinion , but I am shocked the moderators have allowed this thread of potentially dangerous posts.  I hope no one here will take it too seriously and follow your diet which can be very harmful.

  • luv_gardening
    luv_gardening Member Posts: 1,393
    edited April 2012

    Purple, the moderators can't stop people from having different points of view as long as they aren't giving individual medical advice.  They can delete posts that are spam or abusive.  Generally forums are self correcting as people will quickly jump in to point out factual errors.

    Your post is the perfect example of how bad ideas that are out there on the net can be challenged. If they weren't aired here, then they would be allowed to go unchallenged.

    Not that I'm passing any judgement on the Ketone diet which may well have the limited but important ability to put people into remission, the same as chemo does.  I have yet to look for studies on this subject but it's on my list of priorities.

  • KatRNagain92
    KatRNagain92 Member Posts: 522
    edited April 2012


    This is really fascinating Paul! Thanks for all this wonderful information and your sense of humor: "wave goodbye to the doc and the psychiatrist, but keep on good terms in case you break a leg." (that's pretty funny!)

    The ketone diet is a modified version of what I'm doing. I have given up roughly 95% all refined sugar after 5 weeks on Protocel. I still have the occasional "water beer" and pizza crust but I never did have a sweet tooth so this has not been hard for me. I have bran flakes with unsweetened almond milk every morning and I think my water intake on the whole is much higher which may be more neutralizing. (What are your thoughts on distilled water?)  It's also recommended I have red meat about twice a week. You're right about loss of appetite...I've lost about 8 pounds since I began my regimine but feel very confident that I'm starving plenty of cancer cells by interfering with their energy production. 

    I do have some concerns in regards to my body turning on me (yet again) and suddenly making its own sugar despite what I do. It let me down before when it converted the Tamoxifen in to a food source so it's talented that way. Do you have any input on that?

    Anyway, thanks and keeping the information coming. Nutrition is probably the hardest obstacle because there are SO many confusing and conflicting theories.

    Kat

  • Anonymous
    Anonymous Member Posts: 1,376
    edited April 2012

    Hi Kat, what do you mean when you say that your body converted Tamox into a food source ? I'm taking a break from Tamox after two years and don't know if I'll get back on it 

  • KatRNagain92
    KatRNagain92 Member Posts: 522
    edited April 2012

    Maud, my Oncologist said I was one of those rare metabolizers that does in fact convert Tamoxifen to a food source for the cancer.  They have suspected this happens for some time.  It used to be you were on Tamox for 10 years, then they saw signs of this happening in various women so they decreased the standard to 5 years.  Now, my Onc says 3 years and then they would rather catapult you into surgical or chemical menopause.  For me, it was 2 years. 

  • Anonymous
    Anonymous Member Posts: 1,376
    edited April 2012
    Wow, thank you so much for sharing, never ever heard of that one before - what test did your onco do to determine that ?  I sure want to find out if I'm one of those metabolizers ! I see you're stage IV, I'm sorry Frown Are you doing Zoladex then AIs ?
  • KatRNagain92
    KatRNagain92 Member Posts: 522
    edited April 2012

    There's a test..the CYP2D6 that you get done initially,  prior to going on Tamox to find out if your a slow, medium or fast metabolizer of the drug.  If you're slow, they don't even bother putting you on it and try and find another solution.  I would think the ideal metabolizer of tamoxifen would be the mid range group.  I was the fast one and that didn't work out so well for me...But that is based on my own experience. 

    No, I'm not doing any more chemo...I started down the alternative path about 2 months ago and I'm not looking back.  It's working for me!  Smile

  • Anonymous
    Anonymous Member Posts: 1,376
    edited April 2012

    Thanks Kat !  I'll ask the onco to do the test, although I probably won't get back on the drug. Am taking a DIM combo which gives me a lot of confidence plus loads of other supps

    You are an inspiration to me ! please join us on the other alternative threads, we would benefit greatly from your input !

    I'm also hoping Paul returns, lots of good info - would also like to know his thoughts about distilled water which I drink only occasionally since I was told it leaches minerals

  • KatRNagain92
    KatRNagain92 Member Posts: 522
    edited April 2012

    Well thanks Maud!  I certainly feel more welcome on the alternative threads! 

    Smile

    I hope Paul comes back too.  He's like having our own personal nutritionist...and I need one of those! :)

  • elimar86861
    elimar86861 Member Posts: 7,416
    edited April 2012

    KatRNagain92,  How did your doctor know you converted Tamoxifen into a "food source" for cancer.  I have not heard anything about that.  Is there a test for that?

    The CYP2D6 is actually for low, moderate, or extensive metabolism of Tamox.  Not for speed of metabolism, but quantity.  The optimum is to be an extensive metaboliser, meaning the largest amount of Tamox. that you ingest gets converted to endoxifen, which then blocks the estrogen receptor sites.  (About 10% are low metabolisers; Tamox. is effective for the rest.)

    Sorry to stray off nodules topic.

  • Kadia
    Kadia Member Posts: 314
    edited April 2012

    I thought the CYP2D6 test was now not considered a useful (or predictive) test. There was a lot of discussion of it on the board after last year's San Antonio conference. I'll see if I can find the thread(s)...

  • DianaNM
    DianaNM Member Posts: 281
    edited September 2012

    Looks like there is some research going on this subject. Not a big study, but a start:

    www.ncbi.nlm.nih.gov/pubmed/22840388

    Hope that works, was not able to copy and paste. 

  • lightandwind
    lightandwind Member Posts: 754
    edited September 2012

    In putting things together logically, I have to question a ketogenic diet for bc.  I know it has it's merit in weight loss as I can personally vouch for. It is my understanding that a ketogenic diet leads to an overly acidic body. This acidity is a precursor to candida. candida is a precursor to cancer. Without enzymes, antioxidants, flavionoids, caretenoids of live fruits and vegetables, how can we obtain the nutrition that the immune system and healthy cells need? i am putting these things in the form of a question because I can't possibly supply all the links that have lead me to this.  I can't post even the one link right now for some reason, but you can go to their site at baumancollege.org.  I went to their webinar online called  Nutrition strategies for breast cancer and recovery from treatment. It was filled with well backed info about the science of food and bc. I believe there is some merit to the elimination of refined sugar in a ketogenic diet that is important in fighting cancer. but how can you eat a ketogenic diet and get ellagic acid from berries, enzymes, vita c, minerals and antioxidents from fruits and vegetables to build the immune system? If someone can answer this. i would be interested to know.

  • DianaNM
    DianaNM Member Posts: 281
    edited September 2012

    In the studies etc I have seen, you only go on the diet for 2-3 weeks at a time, 2-3 times a year. Then you add the veggies back.

  • Anonymous
    Anonymous Member Posts: 1,376
    edited September 2012

    A ketone diet has been proven to help people who suffer seizures from epilepsy. I wonder if a study has been done on this subject.

    I am on a Atkins modelled ketone diet combined with an alkaline diet so my body is in a constant alkaline/ketosis state because I strongly believe it is helping BUT I'm also on targeted and hormone therapies after having surgery and chemo. If I do come out the other side I wont know which 'approach' has helped with the cancer the most as I choose both but if I do come out the other side I wont care which one helped, I'll just be greatful !!!

  • new_direction
    new_direction Member Posts: 449
    edited January 2013

    I believe there is some great potential in this. I found out about the low carbohydrate diet by reading a book of Johannes Coy, a german researcher.
    Before christmas I started the diet and maintained it until my last chemotherapy (after which I eat whatever I like just to get by), but there is no doubt in my mind - something happened - and I will continue the diet now. The first days were a real struggle but on day 4-5 I found myself waking before the rest of the family - energized like almost never before. It may sound maybe too good to be true, but I could feel my body loved it.

    I soon found recipes to bake "bread" and there are many ways to get a great snack or dessert - dark chocolate, one of my best friends Kiss

    In the book he also mentions the importance of;
    Vitamin E - the subtype gammatocotrienol - I ordered the tocomin suprabio which has the "right" composition.
    Vitamin D and sunlight.
    Exercise, sleep and anti-stress.

    Also, I have come across Artemisinin as an interesting anti-cancer agent. I take these supplements along with the diet and try to keep the diet alkaline as well. Avoid obvious toxins, switch to organic food. I always thought organic meat was way too pricy. My cancer has now changed my mind - and wow - taste the difference! Beef is something I've never tried for REAL before I was diagnosed.

  • Ikari
    Ikari Member Posts: 40
    edited January 2013

    A ketone diet does not need to be predominantly meat and limited veg and fruit. As soon as I was diagnosed I decided to do an alkaline diet and read so much info on the internet - my diet consisted of:

    1. Juicing fruit and veg approx 80% of daily consumption was in liquid form

    2. No bread, wheat, pasta, rice, sugar in any processed form

    3. No alcohol or coffee

    4. No meat whatsoever including fish and eggs

    5. No dairy

    (I have previously been on the Atkins diet several times over the last 20 years for weight loss)

    The main intention of my Cancer diet was to alkalanise my body and I obtained urine test sticks from my GP to check the alkalinity.  To my surprise I found that most of the time my body was also in a state of ketosis. 

    I have changed my diet when I started Chemo and have stopped juicing and meat reduction due to the dietary requirements of chemo.

    With regards to lactic acid and the subsequent discussions I believe there may be links - for years (prior to diagnosis)  I have had really weird responses to muscle extertion during exercise and truly believe this had something to do with the Krebs cycle.  Just off the top of my head (and someone may chime in with this) the Krebs cycle is corrolated with a scientist related to one of the mainstream popular cancer diets (is it Harmer? - sorry major chemo brain atm).

    One my thought process becomes more linear I will be researching this - biochemistry is very, very complex. 

  • new_direction
    new_direction Member Posts: 449
    edited January 2013

    Hi all. I was just reading about diet and something about ketone diet came along. I will try to translate some passages from a book by Johannes Coy et al.:
    When reducing carbohydrates, and fats and proteins are increased in the diet the body will start producing ketones. Ketones feed the sugar dependent areas of the brain and the neurons. They also affect the psyche by creating a more "light" mood and lower anxiety. This is especially important when it comes to cancer patients. Anxiety inhibit the natural killer cells which combat cancer cells. By lowering carb intake and exercising ketone levels will rise.
    A study done at the Albert Einstein College of Medicine in n.y. have shown ketones work directly against cancer cells by inhibiting growth and reducing their energy supply.
    A diet high in protein (1,5-2 grams per kilo body weight per day) allows formation of proteins used by the immune system to recognize cancer cells and kill them. Also lowering carb intake will prevent cancerous cells to switch to fermentation.

    Again, must say I love this book. It's very motivational because you get a feeling of "empowerment", like there is a lot you can do yourself.
    I'm back on the diet, have been so for almost 2 weeks. Have not quite had the euphoric feeling as last time (yet) but perhaps it has something to do with all the stress my body is going through at the moment. Finished 8 chemo rounds and just had surgery last Friday...

  • allurbaddayswillend
    allurbaddayswillend Member Posts: 355
    edited March 2013

    There is a newer write-up in Medscape about this subject. A physician sent the link to me but you will have to Google "medscape calorie restriction cancer" to be able to access both an article on The Role of Carbohydrate Restriction in Treatment and Prevention of Cancer (and in that definition discussion of ketogenic diets) and an article titled "Calorie Restriction to Treat Cancer" that has this fascinating quote in it:

    "The commonplace advice to avoid dietary fat is not a good recommendation to give cancer patients. "They should eat a lot of fat and avoid sugar," Dr. Freedland noted."

    (You can try this link but it always asks me to Log In, whereas if I just Google, I can get the article(s) http://www.medscape.com/viewarticle/778613 )

    They are some great articles, especially the longer Carb Restriction article - take the time to really read it.

  • allurbaddayswillend
    allurbaddayswillend Member Posts: 355
    edited March 2013

    hmmm, perhaps this wasn't the thread to add those articles onto considering how evangelic the OP is… oops.  
    and just a small point of info: The Okinawan diet uses sweet potato, not rice, as its main carb source which I think could be important as those are so nutrient rich and, weirdly enough, lower in sugars than white potato.

  • NattyOnFrostyLake
    NattyOnFrostyLake Member Posts: 377
    edited March 2013

    Dr. Tom Seyfried is the author of the most definitive book on this subject. "Cancer as a Metabolic Disease." http://www.bc.edu/schools/cas/biology/facadmin/seyfried.html

    There is also a Facebook group of cancer patients doing the ketogenic diet.

  • Momine
    Momine Member Posts: 7,859
    edited March 2013

    Allurbaddays, thanks for posting the link. I have been looking into this before and am getting ready to try it.

  • Heidihill
    Heidihill Member Posts: 5,476
    edited March 2013

     Of all the metabolic strategies mentioned in the link (thanks, allurbad!) a ketogenic diet is the only one I haven't tried. Still doing physical exercise and carb restriction, though not very good with the latter. I also did intermittent fasting for a year (7-hour daily eating window), on which I lost a little weight. I think you'd have to be careful as to the type of fat consumed. On a daily basis, I do eat nuts and have some olive oil. Maybe this is ketogenic? Obviously I have to learn a lot more. Lol. Keep us posted, Momine!

  • new_direction
    new_direction Member Posts: 449
    edited March 2013

    coconut oil and palm oil (ecological and unrefined) are good fat sources.

    I was on the diet for 2 months but then started radiation therapy and I have craved more fruit in this period, also some "heavy meals" containing brown rice etc so I decided that it was fine to go off the diet while I get radiation.
    However must say it has been very easy once I got started. The sugar craving disappears and although I ate whenever I felt like it and never was hungry I lost a lot of weight (one pound per week). Im at my normal weight so that was also a reason for me to jump of the diet while in radiation...

  • allurbaddayswillend
    allurbaddayswillend Member Posts: 355
    edited March 2013

    Heidihill, your daily intake of calories should probably be about, what, 70%fat I think to be truly keto? with minimal amounts coming from protein because our bodies can make glucose out of proteins too… :/ I'm not doing it either but I'm very good about restricting processed carbs. That I have to be gluten-free already helps me with that and then the glutenfree breads and pastas are so expensive and just put weight on me so I almost never eat those. But what I do is more of a paleo diet where my carbs come from sweet potato, peas, nuts, etc. If one eats a lot of nuts and olive oil, one is supposed to make sure they are getting enough omega-3s from fish to balance out all the omega-6. That's tricky for me. Coconut oil and palm oil as new direction mentioned are good saturated fats.

    new_direction, how do you feel about grass-fed saturated fats? I keep running across research and reviews saying that saturated fats are not the harmful food that we (in the USA anyway) have been told for a few decades. But conventionally fed beef and pork will have so much gunk in their fats (hormones in partick) that those are still a bad idea to eat.

    also, does anyone here who is not diabetic monitor their blood glucose?

    Should we start a new thread? I'm just concerned that the original post is frenetic enough that it will scare people off reading about what is actually a true research area.

  • Momine
    Momine Member Posts: 7,859
    edited March 2013

    Allur, I get an A1c every time I have a blood panel, which is every 3 months, but I do not monitor daily.

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