Would a KETONE Diet Kill Cancer?

As my stance on drugs seems to be causing the most amount of angst on this forum I thought I would clarify that issue first, dealing with the common and more serious disorders.

MIGRAINE. It is far less damaging to the brain to suffer migraines than medicate them with blood vessel constrictors and dilators. The 'vasospasm' (or constriction followed by dilation of blood vessels to the brain) as it is erroneously call by the neurologist doesn't just happen. The first phase, when blood vessels to the brain constrict , and there are visual disturbances and mental confusion is seen as the dangerous phase to be suppressed with vasodilator drugs used prothilactically, because this constriction causes oxygen and glucose starvation to the brain. However this constriction takes place to control a far worse threat, a rise in osmotic pressure in the brain in which neurons can swell and burst. Constrictors, on the other hand taken before nausea starts are to control or minimise the dilation phase from which the headache results. However, this dilation phase is to compensate for the hypoxia and hypoglycaemia resulting from the necessary constriction phase. The brain is trying to juggle two opposing dangers and knows better than any neurologist what to do.

Beta blockers taken prothilactically to control the blood pressure rise of the migraine and thereby minimise the pain/control hypertension can prolong a migraine for days and increase it's severity. This is because, by being adrenalin receptor blockers on the heart and it's blood vessels, they also inhibit the release of fatty acids and glycerol from fat cells and lactic acid from the muscles, all needed by the liver to make glucose and ketones which desperately needed by a brain starved for fuel, so it's blood vessels remain extremely dilated along with the migraine. Unable to eat because of the nausea and the body unable to make fuel, all up a combination of beta blockers, refined sugar and liver pathology made worse by the refined sugar. If someone with migraine is taking beta blockers I recommend seeing their doctor about looking at the possibility that they have more renal hypertension than cardiovascular and swap to an ACE (angiotensinogen converting enzyme) inhibitor just temporarily. Once enough gunk in their blood vessels has dissolved by getting off the sugar they can throw them away.

So I recommend suffering the migraines rather than take take drugs do I? Not at all . If you are fair dinkum you can take the first step tonight and tomorrow morning be totally free of migraine forever. Triggers, like Tyramine, MSG etc. don't cause migraine, they merely exacerbate the effect of refined sugar and, in many cases, be the straw that breaks the camel's back.

SEIZURES.

Sugar?? What happens when a diabetic injects too much insulin? Well, seizures. What happens when someone has a tumour of the pancreas called an insulinoma which spits out insulin 24/7? Epiliptus staticus or constant fits. What does insulin do? Lowers blood sugar. What is reactive hypoglycaemia (perfectly respectable syndrome as even the Mayo clinic recognises it but doesn't know how to test for it properly) low blood sugar in response to high blood sugar? Doesn't that suggest that going off refined sugar will eliminate the low and and therefore the seizures.

As I suggest in the above post on the panic attack, the blackout and convulsions actually protect the brain from potentially life threatening cerebral hypoglycaemia. Another example of Nature being a bit smarter than the neurologist. The symptoms are there for a reason every time. Nature says 'He who hath ears to hear let him hear'. Forget dogma just look and listen and it all begins to make sense. Cut out refined sugar and the seizures will cease, unless you have an insulinoma. Go on a ketone diet and the pancreas becomes redundant and get a rest from the huge swings in destructive osmotic pressure associated with swings in blood sugar.

INSULIN DEPENDANT DIABETES.

Off course you can't throw away your insulin just yet. Just start to manage it a helluva lot better. Most of of the appalling longer term pathology associated with insulin dependant diabetes, blindness, kidney failure gangrene of the extremities etc. is injecting way too insulin, then on the threshold of hypoglycaemia induced seizures or coma. in which case unconscious and unable to respond i.e. dead, is to quickly gobble two Mars Bars. Blood sugar rockets up into the stratosphere along with huge and incredibly destructive osmotic hypertension. On edge of hyperglycaemic coma, another huge shot of insulin and so on. These swing in blood sugar are also moodswings, confusion etc. emotional instability, thereby making management even more difficult and thus worse

Go onto a ketone diet and insulin becomes irrelevant as there is no blood sugar to regulate. You can put the hypodermic an monitor in the cupboard. Now your pancreas will get a complete rest and there's a very good chance those beta cells, now freed of the osmotic pressure swing that probably destroyed them in the first place, can regrow and you'll come out of the ketone diet no longer a diabetic. The you can give your insulin to somebody else. Another miracle of ketosis.

CHOLESTEROL. My post on the ABC Health Report.

When I heard that Statin was on the menu this week I thought "Oh, how boring" but I thought that I'd better have look as one drug and it's action, side effects etc. throws light on another and one learns more biochemistry, endocrinology etc. at the same time Well I'm glad now that I did, One side effect that struck me was type 2 diabetes, 2 presumably being associated with weight gain. Now the diagnostic test of diabetes is as good as useless, 1.75 grammes of glucose per Kg of body weight taken at 9 am after a fast from the previous evening and after taking the first blood test, then one EACH HOUR, three all up. Now I've done quite a few 5 hr GTT's and I found that I HAD to do a test each 15 minutes to start off or miss the peak. One woman I tested went from around 6.5 to SIXTEEN then fell to a low of 4 (a 400% fall) in a bit over an hour and had glucose in her urine. Ok, the standard test will detect glucose in urine but that peak is every bit as important as far as arteriosclerosis is concerned because the arteriosclerosis of diabetes is every bit as much about hyperglycaemia as it is about hypercholestertolaemia. It called non-enzymatic glycosation of protein, glucose acting like a glue binding to proteins on epithelial cells lining blood vessels and trapping cholesterol in this glue.

Now looking at the metabolic pathways the central molecule is acetyle Co enzyme A or acetyl CoA (vinegar with an enzyme) the CENTRAL molecule of all major metabolic pathways in almost all cells. Ethanol (alcohol) is converted to acetyle Co A (via acetaldehyde), as are ketones from the breakdown of fatty acids. But the liver doesn't import fatty acids to convert to ketones except with ketosis. However, look up what's called the glycolytic pathway and you'll see glucose coming in from one side, Here it can go up to be synthesised to glycogen, the storage form of glucose. Come back down to acetyle CoA and it can enter the TCA or citric acid cycle to make energy in the form of ATP, as well as intermediate molecules in the TCA cycle. But too much acetyle CoA into the TCA cycle and citric acid builds up and it inhibits glycolysis,

But what happens if glycogen stores are topped to the brim, made worse by liver pathology limiting storage and no more energy production is needed other than a base level to keep the cell running. There is ONLY one way out, turn acetyle CoA into cholesterol. So the synthesis of excess cholesterol is a BLOOD SUGAR REGULATING MECHANISM. Block it and up goes blood glucose, DIABETES. To me this is one of those examples where the body has to choose between two undesirable outcomes hyperglycaemia or hypercholesterolaemia both of which gunk blood vessels, however hyperglycaemia means very high osmotic blood pressure, so the body chooses the cholesterol outcome. What the patient has to do is dramatically cut back on the sugar intake and chuck the Statin down the loo.

Next Arthritis, Schizophrenia etc.

I have not run away.  My internet connection is so bad because of the Easter Holiday and rain that I have been offline for days and can only just make a connection now.  I may have to be offline for a couple of days to upgrade the system/set up a special camp a mile away where there is good signal. 

Stage 2 Toward The Ketone Diet.

I recently got hold of a Bio -Med paper about a form of treatment for Alzheimers disease using a compound called AC-1202 which is converted to ketones in the liver without having to limit carb input so that ketones and glucose can coexist in the bloodstream at the same time. It was shown to improve cognitive function in Alzheimers patients, seeming to indicate that neurons choose ketones as a fuel when there is a choice. Actually the compound is quite natural despite the name, being made from the glycerine of vegetable oil with the fatty acids from coconut or palm oil combined to make triglyceride. These are very short chain fatty acids of 8 carbons long as against 18 carbons for the omega 3,6 and 9 oils. It may be that plants in the tropics use shorter chain fatty acids to achieve the optimum permeability across cell membranes. The reason that this treatment is used for treating Alzheimer patients is because they develop a sweeter and sweeter tooth as the disease advances, and I'd reckon that an increased sugar intake has a lot to do with CAUSE of the disease. The treatment arose because of the extreme difficulty of getting a very elderly person off the sugar to get into ketosis, which does seem like sloppy way of doing things, but I suppose one has to be pragmatic about these things.

When glucose is present in the bloodstream the conversion of fatty acids to ketones is what all cells have to do when running on fatty acids because ketones are an intermediate between the fatty acids and acetate (ionised vinegar), the central molecule of the major metabolic pathways. However, when in ketosis the liver makes an excess of ketones over and above it's own requirements to supply the rest of the bodies cells instead of them making their own ketones from circulating fatty acids. Why, I dunno, yet. But with AC-1202 the liver is making ketones for export even though there is a normal concentration of glucose in the bloodstream. I'd reckon the answer to that riddle is because of the short length of it's fatty acids i.e. they are easy to beta oxidise, as the process of conversion is called. It may be more complicated than that, however it's not important for what I have in mind.

What if this compound can be eaten as the key to an intermediate dietary stage between the no refined sugar stage and the ketone stage, making it safer and easier to enter ketosis. It would eliminate and chance of having seizures. It could be that coconut/palm oil could be used instead, and ketones in the urine easily tested for with Ames Ketostix. I might try it on myself to get the ball rolling and give a report.

To Zuvant on the mouse ketone diet experiment.

With these mouse experiments, I imagine that the tumours would be induced with a lab carcinogen and lab protocols, not even thinking about the effects of lab stress on the animals as it's not even seen as relevant.  The inability of the tumour cells to metabolise ketomes is seen as a defect in the mitachondria which it is not, it is the cells dedifferentiating, something that is now regarded as wrong thinking as it smacks of Larmarkism.  The diet of KetoKal doesn't limit their blood glucose anywhere near enough to kill even very malignant cells.  They were saying that this should be something to consider further experimentation in the future 20 years ago.  They don't really want the experiment to succeed as their is no money in it therefore no funding from the only source, big pharma.  So what they'll come up with is the conclusion that a ketone diet could prove to be an effective adjunct to be used with conventional chemotherapy, thereby throwing a bone to the naturopathic minded individual and making sure that big pharma keeps a firm grip on 'treatment' and the undertaker happy. Unless a mouse experiment is conducted properly with the end in site being total remission then it's not worth two bob and no lab is gonna do that because they would be cutting theit own throats.  Imagine the millions out of work, research labs closed, hospitals becoming museums, at a time when the world economy is hanging over a cliff.  Trouble is nobody with cancer is going to risk trying a full ketone diet, and NO conventional treatment, without support for the idea coming from researchers and while the oncologist, his surgeon and aneasthatist mate are saying 'If you don't get that tumour removed soon it'll metastasise right through you and it'll be beyond treatmen't'.  Without at least one sucessful remission to inspire...  That's why my post 'A Case of TOTAL Remission' was removed.

To JennT 28

I aimed my research on 500 Cancer researchers every year for about 12 years at the Lorne cancer conference and there was NOBODY I could talk to about this stuff because most were molecular biologists who did not even know simple inorganic chemistry.  An oncologist and a toxicologist told me they had not studied chemistry.  They are all looking for drug targets, applied and no pure science.  I am also a Larmarkian heretic, the Antichrist of biological science world wide.  (How's that for a bit of Schizophrenia.)  For years I wrote little booklets and distributed them at the Cancer and Genome conferences and these went back home with the delegates fom all over the world.  Ketosis is biochemistry with inorganic chemistry to back it up, endocrinology, heamatology, physiology, plant and soil physiology and ecology and on and on.  It is most certainly metabolism, an understanding of every single mechanism and metabolic pathways because miss just ONE important one an miss the whole point entirely.  Yet delegates at both conferences told me that biochemists no longer study metabolism.  Probably because they can just go online and check up the little bit they need to conduct an experiment.  I have yet to see online all of the major metabolic pathways together on one map.  Useless!!!  I had no option than stuff it all into my head beginning forty years ago because there was no online.  Was Galileo's theory put to peer review.  Yeah, shut up or get burned at the stake.  He has my fullest sympathy.

I would like to offer my sincerest thanks to all of the highly competent psychiatric diagnosticians present in this forum at their conclusion that I am a schizophrenic. However, my condition is a far more virulent form and extremely rare, (so rare in fact that only I have it) disorder called MENS (messianic egomaniacal narcissistic syndrome). There is a med for it called thallium (rat poison) but I refuse to take it. So you are right, I am off my meds. Because I am the only person alive that has this condition only I am competent to diagnose it making me the greatest shrink in the unknown Universe. Friends tell me that I have a Jesus Christ complex. I hotly contest this ridiculous diagnoses. It was HE who had a Paul Hill complex. To quote the great LSD deranged philosopher Allan Watts. 'I f I appear to be dogmatic and authoritarian it is purely for the sake of clarity. I do not wish to appear to be an oracle'. I'm now looking for a second opinion as to my diagnoses of me. Unfortunately as only I am competent to give a second opinion of me a row has broken out between us and now we just leave each other notes. Eh!!!

I do not wish him banned, if we could only vote.  I find his information difficult to follow but still realize insights that I need to hear in everything.  I hope he is copy, saving everything.