Cruciferous veggies improve breast cancer survival: study

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FYI. Via Yahoo news (http://news.yahoo.com/veggies-improve-breast-cancer-survival-study-180537250.html)

Chinese women who ate cabbage, broccoli and leafy greens saw improved survival rates after breast cancer than women who did not eat these cruciferous vegetables, said a US study presented on Tuesday.

The findings came from data on 4,886 Chinese breast cancer survivors age 20-75 who were diagnosed with stage one to stage four breast cancer from 2002 to 2006 and who were part of the Shanghai Breast Cancer Survival study.

Women who ate more cruciferous vegetables over the 36 months following their diagnosis saw their risk of dying from any cause decrease by 27 percent to 62 percent compared to women who reporting eating little or none of these veggies.

The risk of dying of breast cancer decreased by 22 to 62 percent for the cruciferous veggie eaters, and their chance of experiencing a recurrence of breast cancer dropped by 21 to 35 percent.

Sarah Nechuta, a postdoctoral research fellow at Vanderbilt University in Nashville, Tennessee, said the findings suggest breast cancer survivors "may consider increasing intake of cruciferous vegetables, such as greens, cabbage, cauliflower and broccoli, as part of a healthy diet."

Nechuta, who presented the study at the American Association for Cancer Research meeting in Chicago, pointed out that diets among Chinese and Western women tend to vary.

"Commonly consumed cruciferous vegetables in China include turnips, Chinese cabbage/bok choy and greens, while broccoli and brussels sprouts are the more commonly consumed cruciferous vegetables in the United States and other Western countries," she said.

"Second, the amount of intake among Chinese women is much higher than that of US women."

Nechuta said future research could focus on the role of the bioactive compounds in cruciferous vegetables -- namely isothiocyanates and indoles -- and how varying doses may have an effect on cancer.

Comments

  • Shrek4
    Shrek4 Member Posts: 1,822
    edited April 2013
  • calamtykel
    calamtykel Member Posts: 1,187
    edited April 2012

    Thanks - this is significant info, as most US studies have implied that  DIM -(made from) the compounds found in cruc. veggies ) was previously thought mainly to benefit post menopausal women.  This study is showing it is beneficial for all ages.   I try to do a kale shake a day since I was diagnosed two years ago.  Cruc. sprouts are also much higher in the compounds throught to halt BC cells.  :) 

  • peggy_j
    peggy_j Member Posts: 1,700
    edited April 2012

    Yes, great news. FWIW, my RO recommended eating cruciferous veggies at least 3x a week, so at least some docs agree with this too.

  • 1Athena1
    1Athena1 Member Posts: 6,696
    edited April 2012

    Genetic differences between people of Chinese origin and people of other ethnic orgins can account for differences in response to an intervention. I'd be very careful of making too much of this. In addition, it appears to be a 36-month study (not a very long endpoint). It's a promising "start" but more study is surely warranted.

    Also, it's good to remember that an "association" between one thing and the other is NOT necessarily the same as a cause-effect relationship.

    But thanks for posting it. The potential anti-cancer benefits of broccoli have been known for a long time. Shortly after dx, I began drinking hot tea made of brocco sprouts until my Tamoxifen-induced hot flashes made that impossible. :(

    Here is another report on the same study with some comments from researchers:

    http://news.yahoo.com/veggies-broccoli-cabbage-may-help-fight-breast-cancer-180208892.html

  • Hindsfeet
    Hindsfeet Member Posts: 2,456
    edited April 2012

    I'm suppose to stay away from cruciferous vegetables due to hypothyroid. I can eat them steamed.

  • Angelfalls
    Angelfalls Member Posts: 849
    edited April 2012

    "The risk of dying of breast cancer decreased by 22 to 62 percent for the cruciferous veggie eaters, and their chance of experiencing a recurrence of breast cancer dropped by 21 to 35 percent."



    Does anyone else find these percentages really high, or am I reading this wrong? Is this really saying that without this type of veg, the risk of dying from BC was 84% across all stages and the risk of recurrence was 56%? Can this be true?



    Angelfalls xx

  • crazy4carrots
    crazy4carrots Member Posts: 5,324
    edited April 2012

    Angelfalls -- I was asking myself the same questions!  And, as Athena says, 36 months of study doesn't seem terribly adequate to come to any conclusions.

  • 1Athena1
    1Athena1 Member Posts: 6,696
    edited April 2012

    We don't know. They don't identify who the "cruciferous veggie eaters" subgroup were - except to say that the entire study included all stages (not the same thing). No inferences should be made. I hate how studies are picked up by the media - they can be so misleading.

    Also, "risk of dying" was within a 36-month period, which was the study period. We know nothing after that.

    I think the media should tread more carefully when discussing studies. They show more caution with presidential polls - probably because campaign PR people are better at complaining to the editor than are bespectacled university researchers. Very irresponsible to treat medical-scientific findings this way. These studies really drive me nuts, the way they are peddled.

    I hate to say this, but behind the rhetoric, we don't learn much of value here.

    Thank you for listening to my rant. :-)

  • Angelfalls
    Angelfalls Member Posts: 849
    edited April 2012

    I agree absolutely! When something as basic but crucial as the death and recurrence stats seem to be so meaningless and/or wrong, I personally would find it hard to take much positive from this report. But I love my greens! ;o)

  • BouncingBetties
    BouncingBetties Member Posts: 379
    edited April 2012

    I ate a ton of cruciferious veggies before ending up with breast cancer, along with a lot of the other foods they say prevent cancer, so I don't quite buy this study. I am taking BroccoGen10 broccoli capsules just to err on the side of caution but I think that there may be a genetic component to this. Also, as noted by Evebarry, cruciferious veggies aren't good for people with thyroid issues. Over consumption can actually result in hypothyroidism apparently. I know we're all hoping for a magic bullet, but this study's precentages with respect to death seem questionable. If this study was correct, I would think all of our oncs would be calling to tell us to head to the grocery store.

  • Myleftboob
    Myleftboob Member Posts: 1,469
    edited April 2012

    I too am a lover of cruciferious veggies, have been my whole life.  Love cabbage, brocolli, brussel spouts, kale all of it. Still unfortunatley got BC.

  • elimar86861
    elimar86861 Member Posts: 7,416
    edited April 2012

    That's interesting.  Do the Chinese have a remedy for cabbage-farts?  Oh, I'm serious.

  • Outfield
    Outfield Member Posts: 1,109
    edited April 2012

    They don't say if it's a relative or absolute risk reduction.  I suspect it's relative, which means that for example 21-35% could mean, if the absolute risk of recurrence during those 36 months were for example 5% (pulling that number out of my . . .), an absolute reduction of roughly 1-1.75%.  

    The reason I suspect it's relative is that if it were absolute those women would be experiencing a very high rates of early recurrence and early death and I would have to wonder about their other treatments.  

  • Angelfalls
    Angelfalls Member Posts: 849
    edited April 2012

    Thanks for your explanation, Outfield. That makes much more sense!

    Angelfalls

  • learnin
    learnin Member Posts: 205
    edited April 2012

    Good point Outfield - I agree, must be relative risk reduction.

  • Kaara
    Kaara Member Posts: 3,647
    edited April 2012

    I'm eating more of these type of veggies since being dx with bc.  Also taking a supplement to boost the intake as well.  Diet and supplementation has become my first line of defense against bc.  Surgery removed the tumor and right now I'm NED.

  • calamtykel
    calamtykel Member Posts: 1,187
    edited April 2012

    There are SO many factor when it comes to BC that I dont' think we will ever have the cause-effect single silver bullet.  Outfield - I agree  -the "22-62 percent" is an odd range and it doesn't explain what reduction they are talking about.    However, this study still is interesting and I would like to see it explained further.  I've cleaned up my diet a lot since BC - become a lot more serious about it and it has many more benefits than helping to reduce risk.  Colds and sore throats have become a thing of the past for me (haven't had a cold since one I got while on chemo) and even my allergies are nearly all gone.  I don't suffer from the migraines that I used to, etc.   I feel better in general.  Seriously increasing my raw greens intake especially by blending and shakes has benefited my health visibly and if that includes adding in kale and sprouts, then I'm willing to do it to help reduce my risk of BC even if it only helps a miniscule amount. 

  • BouncingBetties
    BouncingBetties Member Posts: 379
    edited April 2012

    Elimar, you just made me laugh so hard. Thanks ; )

  • Kaara
    Kaara Member Posts: 3,647
    edited April 2012

    Anyone who has survived bc should consider a healthy diet as the first line of defense against recurrence.  I have been on my new diet for about six months now and the difference is remarkable, not only in the weight I've lost, but also how I feel.  The tamoxifen wears me down a little, but I can only imagine how I would feel on my old diet.

  • Windy5
    Windy5 Member Posts: 14
    edited April 2012

    I tried Dim-Plus and it appeared to effect my hypothyriod problem and I had to stop taking it. My thyriod medication had been stabls for over 20 years and after taking dim the tsh levels shot up.

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