Bi-rads 4A for Calcifications...

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shabby6485
shabby6485 Member Posts: 679

Hi to all,

Two new area of calcifications found that need biopsy~ birads 4a.  Would anyone let me know what their outcome was with a birads 4a?  Trying to soothe myself.  Thanks. 

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  • Beesie
    Beesie Member Posts: 12,240
    edited February 2012

    My last biopsy was done before they starting using the 4a, 4b and 4c classifications but I found the following that might ease your mind a bit:

    Clinical implications of subcategorizing BI-RADS 4 breast lesions associated with microcalcification: a radiology-pathology correlation study. 

    ABSTRACT: Currently radiologists have the option of subcategorizing BI-RADS 4 breast lesions into 4A (low suspicion for malignancy), 4B (intermediate suspicion of malignancy), and 4C (moderate concern, but not classic for malignancy). To determine the clinical significance of BI-RADS 4 subcategories and the common pathologic changes associated with these mammographic lesions, a retrospective review of 239 consecutive stereotactic-needle core biopsies (SNCB) for microcalcifications was performed. All 239 SNCBs were BI-RADS 4 lesions, and of these, 191 were subcategorized to 4A, 4B or 4C. Ninety-four of 191 (49%) were 4A, 73 (38%) were 4B, and 24 (13%) were 4C. Fibrocystic change was the most common finding (66/239; 28%) followed by ductal carcinoma in situ (DCIS) accounting for 23% of cases. This was followed by columnar cell alteration with or without atypia (47/239; 19%), and fibroadenoma (45/239; 19%). While 70% (17/24) of BI-RADS 4C category lesions were DCIS, only 21% (15/73) of BI-RADS 4B and 10% (10/94) of BI-RADS 4A were DCIS. Without sub-categorization, carcinoma was diagnosed in 23% (55/239) of all cases with BI-RADS 4. Therefore, subcategorizing BI-RADS 4 lesions is important since it not only benefits the patient and clinician in understanding the level of concern for carcinoma, but will also alert the pathologist. 

    http://www.ncbi.nlm.nih.gov/pubmed/19929890 

  • shabby6485
    shabby6485 Member Posts: 679
    edited February 2012

    Thanks Bessie,  That is really helpful.  I am really not new at this calcification thing.  This will be my 5th biopsy for these. sigh.  Are you aware of any stats for "fine heterogeneous calcifications"?I have two new areas of these and am scheduled for a stereotactic next week.  Your help is always much appreciated.... 

  • TifJ
    TifJ Member Posts: 1,568
    edited February 2012

    Shabby- the radiologist took me into his office after my mammo and ultrasound and never said "I think you have cancer", but he pointed out what was good and bad and I was looking at the bad. He said the highly suspicious calcifications are those that are linear and branch out. That is what I had and I did have DCIS, but I also had a visible tumor. He classified me as Birad 4, but it was probably because of the tumor first.

  • Mulligan
    Mulligan Member Posts: 205
    edited February 2012

    Hi Shabby

    Like Bessie I was classified before the whole 4a,b,c. My mammo showed microcalicifications with BiRad 4. I was scheduled for a stereotatic biopsy but they couldn't get to it since it was right next to my nipple and I actually ended up getting a lumpectomy and the results turned out that It was intraductal papillomas (benign tumor).



    I know it's easier said than done, but try not to worry about it.



    Jules

  • CTMOM1234
    CTMOM1234 Member Posts: 633
    edited February 2012

    Like Bessie and Jules, my biopsy was before the 4-rating was further divided into a, b, and c. My BiRad4 was based on a cluster of micro-cals on an annual mammogram (first time I'd ever even heard of a calc) in my early 40s and a stereo. biopsy confirmed a dcis diagnosis.

    Wishing you the best. 

  • mommy23kids
    mommy23kids Member Posts: 51
    edited February 2012

    Hi shabby,

     I had birads 4a and I was diagnosed with ADH Atypical Ductal Hyperplasia. Hope ya get benign results.

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