Chemo and Breast Cancer

Options
178101213

Comments

  • suzieq60
    suzieq60 Member Posts: 6,059
    edited December 2011

    Taxol is derived from a plant. I believed in a 50% advantage not 2% in my case.

  • thats-life-
    thats-life- Member Posts: 1,075
    edited December 2011

    suzie, is that the 50% advantage we hear of as in 2 people out of 100 will benefit with it, as opposed to 1% without it scenario? Im asking that seriously.

  • thats-life-
    thats-life- Member Posts: 1,075
    edited December 2011

    If you personally, are genuinely assured of a 50% reduction in recurrence risk, then i can understand why you would choose that treatment option. But when you made that decision, did you research the short and long term outcomes of chemotherapy as a treatment choice? was it an informed decision? Accepting the potential risks to your heart and immune system? if so, dont you think others have a right here to research, question, and discuss their decisions, without being distracted by one liners?

  • suzieq60
    suzieq60 Member Posts: 6,059
    edited December 2011

    I didn't want to have chemo, no one does. I went in to it with eyes wide open and was very well researched before I saw the oncologist to the point of telling him what treatment I was having which BTW is what he recommended. There was no way I wanted Andriamycin and told him so. I was told there was a 23% chance of recurrence and chemo/herceptin would halve that - that's where the 50% reduction in risk comes from.

  • bluedahlia
    bluedahlia Member Posts: 6,944
    edited December 2011

    Where have I rammed my treatment options down anyone's throat?  Someone is projecting again.

  • bluedahlia
    bluedahlia Member Posts: 6,944
    edited December 2011

    Go to school.....become a doctor.  Then we'll talk.  Stop watching quackery on youtubes, and ramming that junk medicine down our throats.

  • Moderators
    Moderators Member Posts: 25,912
    edited December 2011

    Ok ladies, just a reminder to please keep this civil and respectful. Everyone here has a right to their opinions; if you do not agree with those opinions, there is always room for a healthy, respectful debate. Please keep in mind that this thread is in fact in the Alt forum, and therefore it shouldn't be a surprise to anyone that there are alternative theories discussed here. If you are not comfortable with the topic at hand, move on and choose another forum to comment on in which you do feel comfortable. This goes for all sides of this debate, and for future debates as well.

    Thank you for continuing to maintain a RESPECTFUL and PEACEFUL atmosphere.

    --The Mods

  • suzieq60
    suzieq60 Member Posts: 6,059
    edited December 2011
    Interesting that Alternative Medicine is defined above as "Alternative medicine refers to treatments that are used INSTEAD of standard, evidence-based treatment." Therefore implying that alternative treatment is not evidence based.
  • AlaskaAngel
    AlaskaAngel Member Posts: 1,836
    edited December 2011

    Whether or not some alternative treatment is based on evidence, the definition given does imply that.

    But at the same time, with the exception of a few new trials for very limited groups, conventional medicine has failed to allow alternative options (such as trastuzumab) to be tested alone against chemotherapy alone, so that leaves chemotherapy not based on evidence that it is better than other options.

  • Hindsfeet
    Hindsfeet Member Posts: 2,456
    edited December 2011

    Is there evidence that all the treatments the FDA approves are evidence based? Is this why I continually hear on TV lawyers asking if you took this and had problems with a FDA approved drug to contact them.

    Is chemo a cure for cancer? Evidence?

    Rather, chemo, alternative are whatever we choose are ways to fight the cancer...no evidence to a cure.

  • impositive
    impositive Member Posts: 629
    edited December 2011

    FDA approval is not the holy grail.  Some drugs have been helpful and some drugs have been harmful...some fatal.  Also, just because it hasn't been approved, doesn't make it ineffective.  On that same note, by anyone's definition, BCO is a "conventional" based site.  Just because the Mod's above definition of this forum infers that is isn't "evidence based" doesn't make it the gospel.  If conventional medicine had all the answers we would be cancer free. 

    It's crucial that we are armed with enough information to know what to choose and then pick and choose from each modality if that's our choice.  To be closed minded to any modality is only hurting ourselves.  As eve stated, right now we are collecting tools to win the battle.  For those who want studies, they are out there....look at curcumin, etc.  I want scienced based evidence as as well as empirical evidence.  I value both...I trust neither completely.  It's beyond me why people want to pit one against the other rather than band together and win the war.  This forum could be very useful to those who have undergone chemo, those currently undergoing it and those still scheduled to do so.  When chemo fails us, some may look toward alternatives.  When alternatives fail us, some may look toward chemo.  It's a race, it's a war, it's our lives. I want a discussion that I can gain from.  You dont have to buy it all lock, stock and barrell but I for one am definitely shopping for the "gun". 

    AA, I think you are onto something with the endocrinologist.  If cancer were but a tumor, cutting it out would have healed me but since cancer is a systemic disease that has localized and not a local disease that disseminates, we need more than just our BS and Onc's to assess the situation.  Thanks for the links! 

  • digger
    digger Member Posts: 590
    edited December 2011

    Impositive,

    You say that if cancer were a tumor, cutting it out would have healed you (instead of your current progression).  But correct me if I'm wrong, didn't you only have initial surgery and then decline anymore, even with unclean margins from the first surgery? 

  • impositive
    impositive Member Posts: 629
    edited December 2011

    Digger, are you trying to keep me on my toes or bring me to me knees?  You have certainly done your homework on me because that's not in my bio and I haven't mentioned unclean margins for a very long time on these boards.  "My current progression" as you call it isn't in my breast.  Cancer in my breast doesn't show up on an MRI, a PET/CT scan, a thermography, a mammography or an ultrasound . I have recently had them all.  It is in my lymph nodes however... which, since you are keeping track, I had an SNB with 8 node removed...all clear.  So your conventional medicine isn't full proof.   As I said, cancer is a systemic disease that localizes, not a local disease that disseminates.   How many women have had their breasts cut off only to realize the cancer has "come back" elsewhere.

    Your simple injections on the altrernative forums are getting really tiresome.  (yawn)

  • Beesie
    Beesie Member Posts: 12,240
    edited December 2011

    I've been trying to stay off this thread but impositive, what you said really interests me:

    "As I said, cancer is a systemic disease that localizes, not a local disease that disseminates. How many women have had their breasts cut off only to realize the cancer has "come back" elsewhere."

    I've never thought of it that way and thinking about it now, I don't think I agree (but I admit that I need to mull it around quite a bit more).  I also don't see your example as supporting your statement.  If BC starts in the breast and then disseminates through the nodes or vascular system, wouldn't that explain perfectly how it can be that a woman might have a BMX and yet the cancer later 'comes back' somewhere else in her body?  Those are the BC cells that disseminated from the breast prior to the BMX.  Every cancer is unique - a BC cell that is found in the liver can be identified as being a BC cell and not a liver cancer cell.  So doesn't that support the fact that cancer starts locally and then disseminates?

  • impositive
    impositive Member Posts: 629
    edited December 2011

    Yes Beesie, it's true, bc cells can disseminate to the liver, etc. of course.  What I mean is bc cells didn't just spring up in the breast spontaneously.  There was an underlying cause that manifested itself in the breast or colon or wherever our cancer is.  Whether it's toxicity, lack of nutrition, acidity, infectious...whatever the theory is, it's systemic.  Our breasts aren't "sick"...we are.  My reason for a lumpectomy was to rid my body of any tumor load but just ridding the body of the tumor doesn't rid us of the disease.  I have also had melanoma (twice) and basil cell carcinoma (numerous).  These weren't metastasis, they were primaries seven yrs apart (the melanoma.)  My doctors told me I need to closely watch for other cancers, namely breast and colon because statistics show that melanoma patients also present with these cancers.  That's why I says it's a systemic disease which localizes.  

  • crazy4carrots
    crazy4carrots Member Posts: 5,324
    edited December 2011

    I see a "systemic" disease as one which has its origins in one of the body's transportation systems -- lymph, vascular.  I know that some people consider the immune system as a vehicle for transportation of diseased cells, and perhaps this is what impositive is referring to.  However, the immune system is not actually an "interstate" type of route through the entire body.  if it were, then autoimmune diseases* such as rheumatoid arthritis would affect every joint in the body.  It doesn't -- fortunately.

    Beesie brings up an excellent point -- bc cells are indeed identifiable when found in organs or bones, meaning that they have strayed from their original location via either the lymph or vascular systems.

    The other point I'd like to make is that the majority of people dx'ed with bc never see a recurrence or a metastasis. If bc were systemic, I should think this fact would be an unlikely one.

    However, I'm just ruminating here! 

    *Of course there is Systemic Lupus Erythematosus, which can affect every organ in the body. 

  • impositive
    impositive Member Posts: 629
    edited December 2011

    Is that true that the majority never see a recurrence or metastasis?  That is what we can all only hope for. 

    Beesie, what are your stats on that?  I have obviously had a recurrence but seeing stats on that would definitely help give some hope.

  • AlaskaAngel
    AlaskaAngel Member Posts: 1,836
    edited December 2011

    I like the questioning, because it encourages critical thinking, and breast cancer needs better answers.

    "The other point I'd like to make is that the majority of people dx'ed with bc never see a recurrence or a metastasis. If bc were systemic, I should think this fact would be an unlikely one."

    Maybe, maybe not. If, as I think is true, each of our immune systems are constantly dealing with abnormal cells and most of the time successfully, with the abnormal cells going through apoptosis eventually before they can cause trouble... then bc could still be systemic but held in check most of the time. 

    A.A.

  • crazy4carrots
    crazy4carrots Member Posts: 5,324
    edited December 2011

    impositive:  The majority of BC patients who have had some (surgery) or further (chemo/radiation/hormonal therapies) tx are the ones I was referring to as not having a recurrence or mets.  I may be wrong, but I believe the stats show this to be true.

  • crazy4carrots
    crazy4carrots Member Posts: 5,324
    edited December 2011

    A personal anecdote, which may help to explain why I'm skeptical about  cancer as an immune system disease:  I worked in a hospital environment and was exposed to lots of germs.  My last cold (or any kind of illness, viral, bacterial or otherwise) was in 2000.  I had an extremely "healthy" immune system.  I was dx'd with bc in 2008.  Although I required 12 neupogen shots between chemo tx to maintain decent white cell counts, I never became ill, nor have I had any illnesses of any sort (touch wood!) since then.  I seem to have an exemplary immune system so I'd suggest something else (probably faulty a faulty gene, given my family history) caused my bc.

  • impositive
    impositive Member Posts: 629
    edited December 2011

    I just dont know about the genetics theory.  The majority of bc patients have no family history.  But I do see what you mean.  I was never ill either and still and I'm still healthy (knock wood, lol) except for the cancer, though I'm probably not exposed to germs that way you are since you work around them.  BUT, I was highly stressed and didn't treat my body right and believe I did have a breakdown of my immune system. 

  • Shrek4
    Shrek4 Member Posts: 1,822
    edited December 2011

    So please make me understand. By my knowledge, the cancer cells are mutated cells that do not have a normal apoptosis. How does that relate to the immune system?

  • thats-life-
    thats-life- Member Posts: 1,075
    edited December 2011

    The immune system is capable of destroying random cancer cells with mitochondria/ white blood cell attack..it is when cancer cells have the right environment in which to form a tumour, that we then have 'cancer'. The 'cancer' then sends out enzymes to help disguise it from our immune system. Tcell therapy works by attempting to reboot our tcells. The new scientific interest in Metformin as a treatment for cancer works on the 'newly found' mitochondria inside cancer cells. Diet, can have the same positive outcomes as metformin in diabetes trials...

    Breast cancer is a process of triggers (they think)..genetic predisposition/living near a refinery/diet/infection maybe...or alcohol consumption/early puberty/genetic predisposition/stress...there are risk factors, thats all they know...but it is a process of change on a cellular level, that will or will not eventually manifest as Breast Cancer, depending on your exposure to varying risk factors. It is possible, i believe, to change some of those factors in your life.

  • digger
    digger Member Posts: 590
    edited December 2011

    Impositive,

    I'm so sorry you find me tiresome, but you still didn't answer my question outright (you implied it, but didn't actually state it).  It's important to understand the facts of your case in this particular discussion of breast cancer progression.

    Not to belabor anything, but can you just please answer the simple question: did you or did you not have unclean margins after your first lumpectomy, and then refuse to do anymore surgery?

    As for my following your every post, no, I really don't, I have got a life, you know?  But your stating a while back that you refused more surgery even with unclean margins left quite an impression on me. As it would anyone of your sisters.  

    Please answer the question for us so we can all have an informed discussion. 

  • Kaara
    Kaara Member Posts: 3,647
    edited December 2011

    If I think about the history of my bc, it would go like this.  I was on birth control pills for 20 years, had a hysterectomy, then was on HRT for another 20 years, synthetic premarin only, not balanced by progestrone.  I was healthy, active, little or no weight gain, rarely had colds or flu.  My immune system was functioning at optimal levels.  My only issue was a thyroid problem, created after I had the hysterectomy.  I am on meds for that.

     In 2010 I had a series of things happen to me.  First I was stung by bees about five times over the summer with systemic reactions to each one, but did not seek medical treatment.  Late in the summer I got shingles and was put on an anti viral to stop it from spreading (my immune system took care of it nicely).  Around the same time I got a very bad UTI and was on antibiotics for that.  My immune system was working overtime.  I make the mistake of getting a flu shot while all this was going on, which I think further compromised my immune system.  Coincidentallly, I had a suspicious mammo that year, but was cleared after a closer look.  After coming back to Fl that winter, I had several upper respiratory infections, one which required additional antibiotics.  My blood tests that year showed a high CRP level which is indicative of high imflammation in my body, as well as very low levels of vitamin D.

    I immediately started a supplementation program of Vitamin D-3, changed from synthetic HRT to bioidenticals, but didn't really change any of my eating habits which included carbs and sweets.  My mammo in 2011 was once again suspicious, and this time it was not resolved.  The area of concern was the same area that was noticed in 2010 but cleared.  Now I have very early stage bc.

    I can't help but think that this small pre cancer was in there all along but was kept in check by my healthy immune system.  It was only after my series of immune compromising events that it began to get out of control to the point that it began to show up as a small developing bc.  

    All that being said, it was a huge wake up call for me to change my diet and lifestyle so that I can keep this from happening again.  Already my vitamin D levels are up to the normal range, as is my CRP level.  I have lost a lot of weight that I carried around my middle that was probably producing and storing estrogen.  I'm due to have the lumpectomy soon and pray that will take care of it.  If I need to consider radiation, I will give it serious thought, but to put chemo or other anti hormonal drugs into my body and compromise what I have worked hard to improve, will not be an option for me at this juncture.   

  • 1Athena1
    1Athena1 Member Posts: 6,696
    edited December 2011

    It appears that our genes carry within them the ability to mutate though how this happens varies. Reverse transcription may play a role. Something as trivial as an inflammation could set off a chain effect. The immune system vulnerability may thus be written into our system in contrast with outside immune vulnerabilities. These are some theories discussed in "Emperor of All Maladies" amongst other places.

  • angelsister
    angelsister Member Posts: 474
    edited December 2011

    New research suggests that chemo 'can save the life of 1 in 3 women with breast cancer' the lancet today meta analysis of forty years of bc trials also suggests no evidence of long term outcomes being adversly affected.

  • angelsister
    angelsister Member Posts: 474
    edited December 2011

    Thanks i didn't know how to post that link

  • angelsister
    angelsister Member Posts: 474
    edited December 2011

    Could the mods make a hot link direct to the lancet article?

Categories