Metformin-Sugar-And Totally Paranoid

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Pure
Pure Member Posts: 1,796
edited June 2014 in Stage III Breast Cancer

So if this study on metformin comes  to be true is what it saying that high levels of gluecose can cause inflamation and then cancer?

So then Metformin LOWERS your level of insuilin in the blood? 

Here is where the paranoid part comes in-I eat 2-3 servings of fruit per day ( which is natural sugar) and have a sweet 3-4 times a week. The rest of the time I eat really really clean... But should I be not having sugar at all?

The carbs I can do without-I hardly ever have carbs... 

I guess what I am saying is if this study is true does this mean Sugar should be totally out?

Comments

  • elmcity69
    elmcity69 Member Posts: 998
    edited July 2011

    sigh. this damned sugar-cancer link is depressing (well, i guess only for those who overindulge in it!)

    from what i've read, fruit is better than the processed junk (ie, cookies, cake, ice cream etc). i don't think your intake is problematic. i would ask the doc.

    let's face it: cancer takes much from us, and is a shadow over our lives, even as we enjoy cancer free life! too many women who "did everything right" wound up with this shit - and we all know people like my wonderful (i mean that sincerely) 47 yo cousin, who has smoked 1 - 2 packs cigarettes A DAY since her teens, works overnight shift, has considerable stress (long story), and doesn't seem to watch diet or do exercise. and has never had you-know-what.

    i still say cancer is complicated. sounds like your're doing a great job of being healthy, jen..so go easy on yourself. did you ask your onc about Metformin?

    hugs

    j

  • Pure
    Pure Member Posts: 1,796
    edited July 2011

    Thanks:) No I have an email into her though.. I know now I am super paranoid about the sugar I am brining in..and well I am truly addicated to sweets. I don't drink, I exercise like a nut, eat 7-10 fruits and vegetables per day but HAVE to have some sort of sweet daily... And I also love fruit...This stuff is all so confusing!

  • amoccia53160
    amoccia53160 Member Posts: 57
    edited July 2011

    Everything in moderation. We have to live!

  • voraciousreader
    voraciousreader Member Posts: 7,496
    edited July 2011

    Since being diagnosed with a rare genetic metabolic muscular dystrophy 15 years ago, my husband has had to be on a low carb diet.  I have found it to be a very easy diet to follow.  In fact, when people visit my home they are dumbfounded to find an abundance of food and no one over weight.  The thing to remember with a low carb diet is that there are carbs and then there are carbs.  Not all carbs are alike.  You want to include in your diet foods that are rich in LOW glycemic carbs. Usually, low glycemic carbs translates into high fiber.  And remember, EVERYTHING you eat, in moderation is healthy.  If you want that sweet...then have that sweet.  A diet is a culmination of what you eat over a day, week and/or a month.

    A side story...my dear friend was recently diagnosed with diabetes.  After just a few days of incorporating many of the my husband's foods into her diet, she feels so much better and has so much energy.

    I like the info coming out on the Metformin, but I think if we can make successful adaptations to our diet and have the same outcome, I'd rather stick with the diet then add an additional med to my cocktail.  JMHO.

  • Pure
    Pure Member Posts: 1,796
    edited July 2011

    Voracious reader! Thank you so much  for this....I am going to check this out!

  • jennyboog
    jennyboog Member Posts: 1,322
    edited July 2011

    I'm not trying to get into a debate over this because to tell the truth I don't know enough about it and I'm so confused....I hear stay away from sugar but when I asked my dr. she said, "you should do ALL things in moderation, try to eat healthy but you can have sugar".  And then I found this article, which supports that but then other material says to avoid it.....it's all so confusing & I love my carbs Frown

    http://junkfoodscience.blogspot.com/2008/03/do-you-fear-sugar-might-cause-cancer.html

  • everyminute
    everyminute Member Posts: 1,805
    edited July 2011

    Here is some info from the Sloan Kettering website  - I am not sure what it means though it says :

    http://www.mskcc.org/mskcc/html/101701.cfm

    These data suggest a potential use for metformin and its more potent analogue phenformin as cancer prevention agents.

  • Annie62
    Annie62 Member Posts: 1,081
    edited July 2011

    Well maybe a biochemist can correct this if I'm wrong, but it is my understanding that ALL foods - proteins, fats, carbs are broken down into glucose - fuel for the body.

     I asked my onc about metformin last week and she said that no oncs are prescribing metformin just for it anit-tumor properties. That is not what I'm reading on BCO. But I also had my blood sugar tested recently and it was low so I'm assuming that blood sugar didn't 'feed' my cancer.

    I'm keeping an eye on what is going on with metformin. It would be great if it was a therapy since it seems to have few SEs.

  • voraciousreader
    voraciousreader Member Posts: 7,496
    edited July 2011

    Annie.. You are correct. There are enzymes that break down food beginning with carbs, then fats and least efficiently by amino acids and create glucose that fuels the body. When we eat... Our bodies first metabolize carbs. After an hour or two or following exercise, our bodies then use fats. Whatever extra calories we don't use will eventually stored as fat. What you don't want to happen is... Have your body use too many amino acids or use your body's muscle for energy. The body, when in proper health and a proper diet uses food efficiently to produce energy. When people have metabolic genetic disorders or metabolic conditions like diabetes, the body cannot create energy efficiently or properly which ultimately can be catastrophic.





    Regarding that MSK blurb, my understanding is that in the lab Metaforin is creating an environment on the cell level that is curtailing proliferation. Whether or not that will lead to clinical trials, I guess is too early to say... But it is promising research and nice to see.

  • voraciousreader
    voraciousreader Member Posts: 7,496
    edited July 2011

    It looks like there are trials. Or pre clinical trials... Hmmmm... Interesting.

  • faithfulheart
    faithfulheart Member Posts: 544
    edited July 2011

    What type of dx do you need to have to get prescribed this drug? I was givin this drug years ago to get pregnant, my endroconologist told me I WAS INSULIN RESISTENT, I took the drug for about 3months, it got me prego ,and I had tried everything .All I know is for me estrogen is my enemy, I just have to keep it at bay!!!! No ovarie's, tamox, keep weight down ect... I am with you Sherri ,I have my piece of dark swiss choc, a couple time's a week. Try organic blueberrie's with whip cream and the choc. it's a balancing act!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

    I am going to talk to my onc.about this drug too! I see him in sept. He is always on the cutting edge

    of the latest stuff, I will report back on his take on it too!!!!!!!!!!!!!!!!

    hugs

    steph

  • Annie62
    Annie62 Member Posts: 1,081
    edited July 2011

    Thanks voracious reader for the clarification.

    This is how I see it. I eat very little sweets. I eat a balanced diet with only very occasional refined carbs (occasionly piece of a baguette).  I am losing weight to achieve my 'ideal' weight to reduce estrogen output from body fat. With the exception of cancer, docs always tell me I am extremely healthy and have great stats (blood pressure, blood sugar etc). My only vice is wine drinking which I know has lots of carbs. So if I eat dessert a couple of times per month, enjoy 1-2 servings of fruit per day and the occasinal white potato - I don't think its 'feeding' my cancer.

     I think its great for people to improve their lifestyle and learn as much as we can, but even if you stop eating sweets, but continue to eat too  many calories - you will have more glucose in your bloodstream.

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