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lkc
lkc Member Posts: 1,203
edited June 2014 in Stage III Breast Cancer

Latest news Metformin for BC.

Please all check it out. I have always beleived in the strong correlation of glucose metobolism & BC.

Please google latest research on this.

 I am on board.

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  • bak94
    bak94 Member Posts: 1,846
    edited July 2011

    I am thinking of asking my mo to prescribe. Seems to help with making chemo more effective.

    http://www.breastcancer.org/treatment/chemotherapy/new_research/20080606b.jsp

    That article is from 2008, would love to find some newer research if anyone is aware of any.

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  • jennyboog
    jennyboog Member Posts: 1,322
    edited July 2011

    Thanks, I'll take a look.

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  • lkc
    lkc Member Posts: 1,203
    edited July 2011

    Hey Sherriand all,

    I am happilly already on it(as of  just this week) It is ridiculously inexpensive , $4.00 per mo in the US.

    Ladies, please do your research and speak to your doctors.

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  • LuvRVing
    LuvRVing Member Posts: 4,516
    edited July 2011

    There are several clinical trials currently underway in Canada.  I have been on 2000 mg of metformin for more than a year because I have Type 2 diabetes, and I took 1000 mg for most of the past ten years.  That said, I had an initial IDC diagnosis last June and a local recurrence (or possible leftovers from last year) this March (long story).  The metformin didn't seem to lower the ki67 (mine was 90%) which is one of the thoughts.  I am on chemo now, we'll see if I have a complete pathological response although the only way we'll be able to tell is if the involved intermammary nodes are clear after chemo.

    Another clinical trial involving metformin is as a replacement for tamoxifen or an AI.  The thought is that it could be used with TNBC as a long term preventive. 

    Linda is right, the drug is crazy cheap.  If you need to lose a few pounds, it will probably help you.  If you have insulin resistance or are pre-diabetic, it will help.  If you have polycystic ovaries, it will help. 

    Metformin can cause a bit of GI distress at first.  Usually doctors will start you on a low dose and then gradually increase it as your system adjusts.

    I haven't seen any recent results of the clinical trials.  I wish they would publish some interim statistics. 

    Michelle

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