The importance of inflammation
I was reading a text at my office: Medical Care of the Cancer Patient,
http://www.amazon.com/Medical-Cancer-Patient-Sai-Ching-Yeung/dp/1607950081
And, the first pages of the book addressed lymphedema, but there was an entire section on the experience of "sickness" due to inflammation vs. the experience of depression and how they overlap and how common "sickness" is in cancer patients--the disease and treatment cause inflammation.
And, a lot of the lymphedema researchers are working on the very large role that inflammation plays in LE.
So, I figure, they have to be linked in some way, and a bunch of us have expressed frustration and despair--out of proportion--when we flare, and I think I stumbled across a possible explanation.
It's a whole chapter, and I can't seem to find a way to copy it, but it made a ton of sense.
I guess I should read the text more often--our internet is out (at work), and I was trying to research something, and it's nearly impossible without the internet. But I did appreciate this textbook.
Kira
Here's the description on Amazon, and it's written by a couple of oncologists at MD Anderson
Product Description
Recent therapeutic advances in cancer treatment indicate that rather than a killer, cancer is becoming a chronic disease. This comprehensive text is the first to define and address the broad spectrum of acute and chronic internal medicine disorders that occur in cancer patients and cancer survivors as side-effects of the disease itself, or from treatment regimens. The authors cover non-oncologic aspects of internal medicine such as anorexia, obesity, bone loss, diabetes, depression, pain, fatigue, congestive heart failure, skin disorders, and pneumonia. This book is conceived as a companion to standard internal medicine and oncology texts a comprehensive reference resource for internists caring for cancer patients and oncologists in practice. The text is extensively indexed for easy access and retrieval of information.
About the Author
Sai-Ching Jim Yeung MD, PhD Deputy Section Chief of Emergency Care, Associate Medical Director of Emergency Center (Ad Interim), Associate Professor, Department of General Internal Medicine, Ambulatory Treatment and Emergency Care, Department of Endocrine Neoplasia & Hormonal Disorders, University of Texas, MD Anderson Cancer Center, Houston, Texas. Carmen P. Escalante MD, Professor and Chair, Department of General Internal Medicine, Ambulatory Treatment and Emergency Care, University of Texas, MD Anderson Cancer Center, Houston, Texas. Robert F. Gagel MD, Professor and Division Head, Division of Internal Medicine, University of Texas, MD Anderson Cancer Center, Houston, Texas.
Comments
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Oh my goodness!
Kira, I'm so delighted to read this, because LE makes me think I'm nutso with my reactions to flares and sometimes just to the stupid condition itself. I feel vindicated!
On the other hand, I don't suppose they have any suggestions about what to do about the rotten inflammation, do they? At least there are good researchers asking that question and already busy with trials to see if they can solve it for us. Praying they'll have the answers before long!
Binney -
Makes so much sense. Often when I flare, a migraine is not far to follow. I am with Binney: good to hear that biology may affect our reactions to this all.
Moogie
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Moogie, I read it and thought "I'm not NUTS, just inflammed!" I really want to try and copy out the salient points. Interesting that the "sickness" has psychological impact as well. I did copy at least one page and will try and distill the information.
My younger daughter was hospitalized with status migrainous, and after that we all realized how much migraine is in the family, and I went to a ton of lectures on migraine, and our family takes the migraine suppelements that have been studied: magnesium, riboflavin, fish oil and coQ10.
I spoke to the pedi neurologist who did the study on fish oil, and his "control" was olive oil and everyone did well--both anti-inflammatories.
Kira
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So maybe there is a reason I have felt blue lately when I should be happy? Tuesday will be my one year NED but I finding myself crying over stupid things and worrying about every little bump. Gotta a puff hand again and my under arm area just never gets better. uggg
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Dr. Francis was all about how I have an abnormal inflammitory response...my le thought so too....she even wondered if it was lupus or arthritis....fun!
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It all makes sense. Have a bad migraine now after a full day of excruciating arm pain. Maybe muscle tension plays a part, but I think inflammation is a key component. Just wish a heating pad was an option, but with LE I figure any heat is dangerous territory. Wondering what my PT will do since I really think some MONDORS is at work, and heat is usually prescribed...
Inflamed girls just flame one!
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Moogie, a little focal heat is likely okay--just don't apply a really hot pad for a long time. Some people do well with an ice pack at the back of their neck and sometimes one at their forehead with a migraine.
Hope you feel better.
I would stretch the webs/cords after a warm shower.
Kira
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Thanks so much for posting Kira. I am going to get this book, as I think it will answer some of the "what else should I be doing?" questions. This also gets at something else that was bothering me: why do breast cancer patients have a higher mortality rate overall, not just from breast cancer?
Certainly, when I was getting all my checkups last September, I was more concerned about what my internist would say vs my oncologist. Chemo plus radiation are a major hammering, and I wanted to make sure the rest of me was OK. I was thrilled to learn I am just fine.
I also know that exercise is part of this picture, in terms of keeping my heart strong, weight off, and driving away funks. This is even more critical than prior to diagnosis. My brain works better too when my body is exercised.
So implications far beyond lymphedema. Can't wait to read. - Claire
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