Is there indeed a stage 1a and 1b?

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minxie
minxie Member Posts: 484
edited June 2014 in Stage I Breast Cancer

I found an post from 2008 on this site saying there was no stage 1a and 1b in breast cancer, just stage 1.

http://community.breastcancer.org/forum/93/topic/720711 

I looked on the American Cancer Society's web page on breast cancer and under Breast Cancer Stage Grouping they have

Stage IA: T1, N0, M0: The tumor is 2 cm (about 3/4 of an inch) or less across (T1) and has not spread to lymph nodes (N0) or distant sites (M0).

Stage IB: T0 or T1, N1mi, M0: The tumor is 2 cm or less across (or is not found) (T0 or T1) with micrometastases in 1 to 3 axillary lymph nodes (the cancer in the lymph nodes is greater than 0.2mm across and/or more than 200 cells but is not larger than 2 mm)(N1mi). The cancer has not spread to distant sites (M0).

http://www.cancer.org/cancer/breastcancer/detailedguide/breast-cancer-staging 

and this page has 1a and 1b as well

http://www.cancer.gov/cancertopics/pdq/treatment/breast/HealthProfessional/page3 

This is of interest to me as I was told in 2008 that I was  stage 2a due to micromets, but this system would have me at 1b. In the grand scheme of things I know it makes no real difference but I am curious. Was there indeed a switch in staging description between 2008 and now?

Comments

  • jo1955
    jo1955 Member Posts: 8,543
    edited February 2011

    There is indeed a stage 1a and 1b.  My MO told me I was stage 1a.  I can't tell you if there was  a change in the staging process since 2008.  I have read through some of the threads myself and there does seem to be some confusion.  Your right, in the grand scheme of things, it really makes no difference. The standard of care is pretty much the same for all MOs.

  • Kindergarten
    Kindergarten Member Posts: 4,869
    edited February 2011

    Hi, there!!!! I was staged 2b and the explanation that was given to me, was: I had bi-lateral breast cancer, the biggest tumor in my left breast was 2.1 cm and 1.0cm in my right breast and I had one lymph node involved. I post on the Stage 3 board. I am 6 years out and doing great. Have a great day and God bless you, Kathy

  • BarbaraA
    BarbaraA Member Posts: 7,378
    edited February 2011

    I was staged 1b due to a micromet in one node. I  tried to find staging info and it is confusing to say the least but my doctor told me 1b so that's good enough for me.

  • weety
    weety Member Posts: 1,163
    edited February 2011

    Yes, and there is even stage 1C!

  • mari65
    mari65 Member Posts: 131
    edited February 2011

    My doctors at Mayo Clinic said I was Stage 1C.

  • Valgirl
    Valgirl Member Posts: 187
    edited February 2011

    According to my path report the stage 1a, 1b is relative to the size.  I don't have the paperwork with me but if I recall less than 5mm was 1a and 5mm to 1 cm was 1b.  Again I can't be exact on this as I don't have the paperwork in front of me.

  • Bren-2007
    Bren-2007 Member Posts: 6,241
    edited February 2011

    I didn't know there were A-C on Stage I.  I guess by what Val wrote I would be a Stage Ib. Is stage 1c 1 cm to 2 cm?  But that can't be right, I didn't have micromets, so I must be Stage 1a.

    Bren

  • kira1234
    kira1234 Member Posts: 3,091
    edited February 2011

    valgirl you're right. I'm a stage 1b because mine is 6mm.

  • Beesie
    Beesie Member Posts: 12,240
    edited February 2011

    I think there is some confusion between tumor size and stage differences.  

    Stage I tumors can range in size from less than 1mm to 2cm.  The tumor size ("T" within the TNM classification) divisions are:

    • T1mic - a tumor that is ≤1 mm in greatest dimension.
    • T1a - a tumor that is >1 mm but ≤5 mm in greatest dimension.
    • T1b - a tumor that is >5 mm but ≤10 mm in greatest dimension.
    • T1c - a tumor that is >10 mm but ≤20 mm in greatest dimension. 

    All these tumor sizes can be either Stage IA or Stage IB.  All these tumor sizes can also be Stage IIA, IIIA, IIIC, or IV.  The other factors that determines the stage are nodal status and mets, and for Stage I, it's actually nodal status - not tumor size - that determines if you are Stage IA or Stage IB.

    Breaking Stage I into A and B is new.  This change first came about in the Fall 2010 update of the AJCC Staging manual.  It's interesting to note that the NCCN Treatment Guidelines still don't include this change in their explanation of staging, which suggests that acceptance might not yet be widespread. 

    In any case, it appears that while previously any presence of cancer cells in the nodes automatically moved someone up to Stage II, with this change, they are keeping those with micromets (i.e. nodal mets of no more than 0.2mm in size in no more than 3 nodes) in Stage I. For those with micromets to the nodes, they've created the new Stage IB classification.

    What this means is that if you were Stage I before, you are Stage IA now.  If you were Stage II previously with a tumor that was 2cm or less in size but had micromets in your nodes (N1mi), now you are Stage IB.  There is no Stage IC. 

    Here how this is explained in the AJCC Staging Manual, in their section on Summary of Changes:

    Stage I breast tumors have been subdivided into Stage IA and Stage IB; Stage
    IB includes small tumors (T1) with exclusively micrometastases in lymph
    nodes (N1mi) 

    You can access the latest AJCC Breast Cancer Staging Manual from this website:  AJCC Staging Manual    Just click on "Chapter 32 Breast" in the right hand column.  

  • Bren-2007
    Bren-2007 Member Posts: 6,241
    edited February 2011

    Thanks Beesie .. I didn't think I would be a Stage I b or c because my tumor was less than 1 cm and no micromets in the nodes.

    Bren

  • minxie
    minxie Member Posts: 484
    edited February 2011

    Thanks for the information, Beesie. I have seen some recent studies saying that micromets in the sentinel nodes seem not to have any statistical significance on long term prognosis. Do you have any idea if that's what prompted the change?

  • swimangel72
    swimangel72 Member Posts: 1,989
    edited February 2011

    Thanks Beesie - I better change my signature to show I'm a Stage 1A only........originally I was told it was 1B because of the size. It didn't make a difference as far as my treatment though.........the Her2++++ was the deciding factor for everything, as well as my Oncotype DX Score of 22.

  • Beesie
    Beesie Member Posts: 12,240
    edited February 2011

    You're welcome!

    minxie, yes, it appears that the reason why micromets in the nodes for those with tumors 2cm or smaller have been reclassified as Stage IB, vs. the previous classification as Stage IIA, is because the long term prognosis is only minimally affected by micromets.

    *************************************************************************** 

    Here is an excerpt from pages 20-21 of Chapter 32,  Breast Cancer Staging (or pages 364-365 within the total AJCC Staging Manual):

    Should nodal micrometastases be considered different from
    nodal macrometastases for purposes of overall stage grouping?

    The AJCC Cancer Staging Manual has traditionally grouped breast cancer cases with exclusively nodal micrometastases (pN1mi) as having the same prognostic significance as macrometastases with respect to assigning an overall stage grouping based on T, N, and M categorical classifications. A recent analysis of data in the United States Surveillance, Epidemiology, and End Results (SEER) national cancer database has demonstrated that when nodal tumor deposits no larger than 2.0 mm are the only finding in lymph nodes and the primary tumor is less than or equal to 2 cm (pT1) the incremental decrease in survival at 5 and 10 years was only 1% compared to patients with no nodal metastases detected. Patients with tumors no larger than 2.0 cm (T1) represented 70% of the total population in the analysis, and in this subset calculated 10-year survival decreased from 78% to 77% to 73% for pN0, pN1mi, and pN1a, respectively. This does not justify classifying pN1mi cases with Stage II tumors. This analysis included data from 1992 to 2003 spanning the introduction and widespread adoption of sentinel lymph node biopsy. In this edition of the manual, T1 tumors with nodal micrometastases (pN1mi) will be classified as Stage IB to indicate the better prognosis for the subset of breast cancer patients and to facilitate further investigation. 

    ***************************************************************************  

  • otter
    otter Member Posts: 6,099
    edited February 2011

    Beesie, you are wonderful!  I did not know the criteria for staging with micromets had changed. (I did know the prognostic significance of micromets was under question.)  Thanks so much for your crystal-clear explanation.

    otter (Stage IA, apparently)

  • Beesie
    Beesie Member Posts: 12,240
    edited February 2011
    otter, I didn't know either until I saw minxie's post and decided to investigate.  So a big Thank You to minxie!
  • Anonymous
    Anonymous Member Posts: 1,376
    edited February 2011

    Thanks Doc.  However, some of the studies you quote are over 10 years old

  • cookiegal
    cookiegal Member Posts: 3,296
    edited February 2011

    Intersting...I remember before my final path my surgeon thought I would be a 1B but I ended up a 2A.

  • Valgirl
    Valgirl Member Posts: 187
    edited February 2011

    Well I was told I was Stage 1b due to size 8mm.   I had NO micomets in lymph node.   Guess it depends on who does the pathology and how they report it.

    I am changing my status to Stage 1 as I had no micromets in lymph nodes.  Guess my pathologists used the old guidelines....   I also thought that you could not use the oncotype if there was any lymph node involvement.  My oncotype was 16.  I had lumpectomy and rads - No chemo.

  • Beesie
    Beesie Member Posts: 12,240
    edited February 2011

    Valgirl, to my understanding, up until this 7th version of the Staging Manual, officially there was only Stage I - with no IA or IB or IC. That's still how the NCCN Guidelines show it.  But when you think about it, there can be a lot of difference between someone who has a 1mm invasive tumor (as I do) and someone who has a 8mm invasive tumor (as you do) and someone who has a 1.9cm invasive tumor (which would also be Stage I).  The significance of being HER2+++ or triple negative - and therefore the presentation of different treatment options - kicks in when a tumor is only 6mm in size (or even smaller).  And until the NCCN Treatment guidelines were changed this year to incorporate the use of the Oncotype test, the guidelines used to suggest the consideration of chemo for any tumor that was 1cm in size or greater.  So within Stage I, there can be a lot of differences in treatment. For this reason I think that many doctors logically have wanted to distinguish between these different Stage I diagnoses so they would use the tumor "T" classification as a way to also classify and differentiate Stage I diagnoses. I think that's why so many of the women posting here were told that they were Stage IA or IB or IC, based on the tumor size.

    The problem now is that these unofficial Stage I classifications are inconsistent with the new "official" description of Stage IA and Stage IB.  That's probably going to cause quite a bit of confusion for quite some time.  And by the way, I noticed that although the 7th Edition of the Staging Manual was issued on August 10th 2010, they state the following:  "All of the TNM Staging information included in the Seventh Edition, taking effect for all new cases diagnosed after January 1, 2010, is uniform between the AJCC and the UICC (International Union Against Cancer)."  So I guess that means that if you were diagnosed and staged before January 1st 2010, don't worry about these changes but if you were diagnosed and staged afterwards, these changes do apply.  It also means that although the source of this information is the American Joint Committee on Cancer (AJCC), the staging info that they provide is consistent internationally. That's very important to know - this isn't just an American thing (for all of us on this board who are not in the U.S.!).

    Erica, I'm not sure who or what you were referring to, but the only link that I included in my posts was to the AJCC Staging Manual, 7th Edition, which was issued in August 2010.  The quotes that I included are directly from that version of the manual....if your comment referred to any of these quotes, obviously I can't control what data or studies these doctors/experts used in 2010 to make their decisions about staging changes. 

  • cookiegal
    cookiegal Member Posts: 3,296
    edited February 2011

    Val gal they now do oncotype on node positive.

  • Veryhopeful
    Veryhopeful Member Posts: 35
    edited February 2011

    I agree with Valgirl.  That's exactly what I read.

  • CrazyKitties
    CrazyKitties Member Posts: 180
    edited February 2011

    I am 1B, micromestasis in sentinal node.

  • lago
    lago Member Posts: 17,186
    edited February 2011
  • catbill
    catbill Member Posts: 326
    edited February 2011

    I was told by my onc that I was a Stage 1c (1.2 cm), but that these stages are just pretty much for the pathologists.  Stage 1 a,b,c decisions are based more on their hormone positivity/negativity, HER status and Oncotype if it's been done.

  • Drim
    Drim Member Posts: 302
    edited February 2011

    Thanks Beesie and Lago. There definitely seems to have been some confusion between Staging and T size and you've now cleared that up.

    Lago - congratulations on being done with chemo!!! Hope you're feeling well this weekend!

  • lago
    lago Member Posts: 17,186
    edited February 2011

    Thanks Drim. Chemo done, SE's not so much. I still have major nail bed issues and stiffness… hopfully things will turn around in a few more weeks. My hair on my head is growing back though.

  • ADK
    ADK Member Posts: 2,259
    edited February 2011

    Huh - my radiation oncologist told me I was 1b, but that was almost 5 years ago.  I guess I am a 1a.  Thanks Bessie.

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