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  • CrunchyPoodleMama
    CrunchyPoodleMama Member Posts: 1,220
    edited February 2010

    Anne, a couple of months ago, I bought a Cuisinart pressure cooker (electric), but returned it 3 days later because its cooking pot was non-stick (Teflon). Um, BIG mistake, I'm trying to get away from cancer-causing chemicals like Teflon.

    After doing a lot of research, I splurged on a Kuhn-Rikon 6-quart pressure cooker. It's stainless steel and is used on your stove... I was intimidated at first but now I L*O*V*E this thing!!!!!!!!!!! I'm such a last-minute person (which is why I used to microwave so much junk and that's probably how I got cancer to begin with), this pressure cooker is SO perfect for me. Organic brown rice cooks in 20 minutes (as opposed to 45+ without a pressure cooker)... I can handle 20 minutes!! and like I said, dried beans are cooked in a blink. Vegetables are literally done in 1-3 minutes. (That's another thing I like about my Kuhn-Rikon... I can "instantly de-pressure" the pot by running cool tap water over it. With the electric kind, you have to wait for it to de-pressure and by then the vegetables are soft, pale, mush.)

    I love "Clean Eating" and "Mother Jones" too, and sometimes "Vegetarian Times"... lately, though, I've been sticking to gardening magazines since I'm really determined to grow my own food well.

    Julia (who is soooo hippie/liberal in some ways, soooo conservative in others!!!)

  • RunswithScissors
    RunswithScissors Member Posts: 323
    edited February 2010

    Thanks for the link to Veria. We don't get tv, so it's great that they have a website.

    Between Netflix, Hulu, and getting weather/news online, we don't feel like it's worth the expense, anymore.  (Although having lived so long without  sure made watching  tv while I was getting my chemo  a special treat - I do miss foodtv and HGTV, but not all those horrible commercials!)  

    I know the new digital tvs pick up "local" broadcasting way better than the old antennae on the roof systems did - but where I live it's too far from the source. 

    My yogurt cheese failed. Frown For some reason it wouldn't strain - it kept plugging up the strainer.  It was out on the counter for a few days so I figured it was time to give up. The dogs loved it, though.   

  • Merilee
    Merilee Member Posts: 3,047
    edited February 2010

    For yogurt or nut cheese you have to add weight to press it down slowly. A brick wrapped in a towel works well.

  • RunswithScissors
    RunswithScissors Member Posts: 323
    edited February 2010

    Thanks, Merilee. Hopefully the next batch will turn out right. I love to make little labneh cheese balls, roll them is herbs and spice and then pour on olive oil. 

    This coming week I'm planning to get back to bread baking. Before dx, I used to bake at least one loaf a week, and from the same dough I kept some aside for Friday night Pizza.  I let that habit go while I was in treatment.  Dh has complained bitterly about bland, doughy,  "boughten" bread ever since, so I want to get back to baking. 

  • RunswithScissors
    RunswithScissors Member Posts: 323
    edited February 2010

    Update on the microgreens -

    The seeds sprouted very fast and the tray of little seedlings looks great so far.  Our weather is very overcast, so today I'm going to put them under lights to keep them from stretching. There are some deep red seedlings in the mix that are so beautiful! I'm not sure if they are beets or some kind of ruby chard... 

    Doing this project reminded me that I wanted to start some living easter baskets this year.  I guess it's time to get going with that. 

    I'm also starting some of the cold weather veggies this week.  I don't much care for broccoli, but dh loves it. I found 3 different varieties to try. All of them are  heirloom varieties (so we can save the seed if we like it and get the same plant next year). All of them are different from the plants commercial growers choose because they don't get ripe all at once.  

    When farms are growing for market, they like to go down the row harvest the whole thing. They developed varieties to ripen at once and be finished. But  when you're growing at home, it's nice to be able to pick a little here and there.  

    Of course the real test is taste. Maybe there will be one among them that makes me change my mind about broccoli.        

  • CrunchyPoodleMama
    CrunchyPoodleMama Member Posts: 1,220
    edited February 2010

    Runswithscissors, that's great that your seedlings are off to a cheery start. What a great idea about living Easter baskets! I guess the "grass" would be sprouts? What else would you put in them?

    I think you're right, with the different varieties of broccoli you're planting, I bet you'll find you like it after all. It's worth developing a taste for broccoli, as we all know! Where did you buy your heirloom seeds? My local nursery has a horrible selection of heirloom seeds so I'm going to place an order online... just not sure where yet.

  • RunswithScissors
    RunswithScissors Member Posts: 323
    edited February 2010

    I put johnny jump ups,(for color and for the edible blossoms),  wheat or rye grass, and radishes in the easter baskets, sometimes herbs. It's a use whatchagot kind of project. 

    The grains make a pretty grass bed for dyed easter eggs or candy eggs.

    Bountiful gardens is a really nice source for seeds. I also like Pinetree Seeds but they are sometimes slow to ship. 

  • RunswithScissors
    RunswithScissors Member Posts: 323
    edited February 2010

    Since completing rads in Dec, I have officially been off all meds - with the  exception of the sleeping pill.

    I want to stop taking that, too, but I hate being awake in the middle of the night.  Anyone have some ideas for an herbal tea mixture that works? 

    I know warm milk is supposed to be great for sleep, but I don't like to drink milk without chocolate in it - blech!  

  • olivia218
    olivia218 Member Posts: 257
    edited February 2010

    Has anyone not taken any medications and tried an all natural diet?

    Olivia

  • Merilee
    Merilee Member Posts: 3,047
    edited February 2010

    Runs with sciccors

    Have you tried Melatonin? Works great for me.

  • havehope
    havehope Member Posts: 503
    edited February 2010

    I do not take any pills either. My "treatment" is dark chocolate, red wine in moderation, combination of nuts, no soy, and organic food. I eat everything,no special diet, but I try to avoid refined white sugar, white bread, white rice, etc.

    In regards to sleeping issue what works for me is drinking water. When I wake up in the middle of night ( actually is around 4 AM) I drink water and I fall back to sleep. I also use a night cream ( it is organic) Badger Sleep Balm (badgerbalm.com) if I cannot fall back and that usually helps, too.

    I am all for balance in my life and I would recommend the book  "Real Food" by Nina Planck. She explains why all foods are good in our life, but you need to know how to balance sugar, fat, and other "bad" foods that are actually not bad.

    Here is something that might help.

    FOODS THAT HELP YOU SLEEP

    What you eat affects how you sleep. One of the keys to a restful night's sleep is to get your brain calmed rather than revved up. Some foods contribute to restful sleep; other foods keep you awake. We call them sleepers and wakers. Sleepers are tryptophan-containing foods, because tryptophan is the amino acid that the body uses to make serotonin, the neurotransmitter that slows down nerve traffic so your brain isn't so busy. Wakers are foods that stimulate neurochemicals that perk up the brain.

    Tryptophan is a precursor of the sleep-inducing substances serotonin and melatonin. This means tryptophan is the raw material that the brain uses to build these relaxing neurotransmitters. Making more tryptophan available, either by eating foods that contain this substance or by seeing to it that more tryptophan gets to the brain, will help to make you sleepy. On the other hand, nutrients that make tryptophan less available can disturb sleep.

    Eating carbohydrates with tryptophan-containing foods makes this calming amino acid more available to the brain. A high carbohydrate meal stimulates the release of insulin, which helps clear from the bloodstream those amino acids that compete with tryptophan, allowing more of this natural sleep-inducing amino acid to enter the brain and manufacture sleep- inducing substances, such as serotonin and melatonin. Eating a high-protein meal without accompanying carbohydrates may keep you awake, since protein-rich foods also contain the amino acid, tyrosine, which perks up the brain.

    To understand how tryptophan and carbohydrates work together to relax you, picture the various amino acids from protein foods as passengers on a bus. A busload containing tryptophan and tyrosine arrives at the brain cells. If more tyrosine "passengers" get off the bus and enter the brain cells, neuroactivity will rev up. If more tryptophan amino acids get off the bus, the brain will calm down. Along comes some insulin which has been stalking carbohydrates in the bloodstream. Insulin keeps the tyrosine amino acids on the bus, allowing the brain-calming tryptophan effect to be higher than the effect of the brain-revving tyrosine.

    You can take advantage of this biochemical quirk by choosing protein or carbohydrate-rich meals, depending on whether you want to perk up or slow down your brain. For students and working adults, high protein, medium-carbohydrate meals are best eaten for breakfast and lunch. For dinner and bedtime snacks, eat a meal or snack that is high in complex carbohydrates, with a small amount of protein that contains just enough tryptophan to relax the brain. An all- carbohydrate snack, especially one high in junk sugars, is less likely to help you sleep. You'll miss out on the sleep-inducing effects of tryptophan, and you may set off the roller-coaster effect of plummeting blood sugar followed by the release of stress hormones that will keep you awake. The best bedtime snack is one that has both complex carbohydrates and protein, and perhaps some calcium. Calcium helps the brain use the tryptophan to manufacture melatonin. This explains why dairy products, which contain both tryptophan and calcium, are one of the top sleep-inducing foods. 

    SNOOZE FOODS

    These are foods high in the sleep-inducing amino acid tryptophan:

    Dairy products: cottage cheese, cheese, milk Soy products: soy milk, tofu, soybean nuts Seafood Meats Poultry Whole grains Beans Rice Hummus Lentils Hazelnuts, Peanuts Eggs Sesame seeds, sunflower seeds 

    BEST BEDTIME SNACKS

    Foods that are high in carbohydrates and calcium, and medium-to-low in protein also make ideal sleep-inducing bedtime snacks. Some examples:

    apple pie and ice cream (my favorite) whole-grain cereal with milk hazelnuts and tofu oatmeal and raisin cookies, and a glass of milk peanut butter sandwich, ground sesame seeds (It takes around one hour for the tryptophan in the foods to reach the brain, so don't wait until right before bedtime to have your snack.) Back to

    BEST DINNERS FOR SLEEP

    Meals that are high in carbohydrates and low-to-medium in protein will help you relax in the evening and set you up for a good night's sleep. Try the following "dinners for sleep":

    pasta with parmesan cheese scrambled eggs and cheese tofu stirfry hummus with whole wheat pita bread seafood, pasta, and cottage cheese meats and poultry with veggies tuna salad sandwich chili with beans, not spicy sesame seeds (rich in tryptophan) sprinkled on salad with tuna chunks, and whole wheat crackers

    Lighter meals are more likely to give you a restful night's sleep. High-fat meals and large servings prolong the work your digestive system needs to do, and all the gas production and rumblings may keep you awake. Some people find that highly-seasoned foods (e.g., hot peppers and garlic) interfere with sleep, especially if you suffer from heartburn. (See gastroesophageal reflux). Going to bed with a full stomach does not, for most people, promote a restful night's sleep. While you may fall asleep faster, all the intestinal work required to digest a big meal is likely to cause frequent waking and a poorer quality of sleep. Eat your evening meal early.

    Heed the sleep wisdom: "Don't dine after nine."

    FOODS THAT KEEP YOU AWAKE

    Caffeine-containing foods top the list of foods that wake you up.

    Here's why:

    As a stimulant, caffeine speeds up the action of not only the nervous system, but of other major body systems, too. Within fifteen minutes of downing a cup of coffee, the level of adrenaline in your blood rises, which triggers an increase in heart rate, breathing rate, urinary output, and production of stomach acids. Basically, caffeine's effects are the reverse of what you want to happen as you go to sleep. Caffeine also prompts adrenal hormones to release sugar stored in the liver, which stimulates sugar cravings to replenish the stores. Caffeine heightens the roller coaster effect of blood sugar swings, producing a quick high after a morning cup of coffee, followed by a downturn in the afternoon. Caffeine's effects in the body are sort of like the law of gravity: what goes up must come down. The morning jolt is often followed by afternoon doldrums. Caffeine also makes it difficult to sleep well.

    Know your caffeine quota. Some persons are more caffeine-sensitive than others. Many adults can take up to 250 milligrams of caffeine a day (the average amount in 21/2 cups of coffee) and experience no sleep problems. Others get jitters after one cola.

    Time your caffeine boost. For most people, the effects of caffeine wear off within six hours, so coffee in the morning will usually not interfere with sleep in the evening. Caffeine-containing beverages at lunch may not affect your sleep, but coffee, tea, or cola in the evening is likely to keep you awake.

    Know what foods contain the most caffeine. As you can see from the chart, coffee, colas, and tea rank highest in caffeine content.

    FOODCAFFEINE (mg.)
    coffee, brewed, 6 ounces105
    coffee, instant, 6 ounces55
    Mountain Dew, 12 ounces55
    Colas, 12 ounces35-45
    Tea, 6 ounces35

    Contrary to what we are led to believe, chocolate is not high in caffeine. Two chocolate chip cookies may contain less than 5 milligrams of caffeine, a packet of cocoa mix contains 5 milligrams, and one chocolate candy bar contains around 10 milligrams. In fact, many people find chocolate desserts that also contain dairy products to actually be a sleep inducer because of the combination of tryptophan and carbohydrates.

    To get the taste of tea with less of a caffeine jolt, recycle the tea bag. Discard the first cup of tea made from the tea bag, which contains the most caffeine, and make another cup. Also, don't squeeze the tea out of the tea bag, as these drops of tea contain more caffeine. Try grain-based hot beverages and caffeine-free herbal teas as alternatives to coffee and tea.

    Some over-the-counter cold and headache remedies are high in caffeine. Check the label or ask the pharmacist, especially if you are a caffeine-sensitive person.

    http://www.askdrsears.com/html/4/T042400.asp

  • yellowfarmhouse
    yellowfarmhouse Member Posts: 279
    edited February 2010

    crunchy poodle mama,

    Thanks for the suggestion of pressure cooking beans.  I wonder.... do you know of a way I can use my crock pot to soften the beans?  like how much water to add -- I could just plug it in overnight I was thinking... we eat a lot of beans....There is a nutritionist in our area who advocates the legumes. 

    thanks,

    Wendy

  • lvtwoqlt
    lvtwoqlt Member Posts: 6,162
    edited February 2010

    Wendy, to cook dry beans in my crock pot, I either soak clean beans overnight or I will 'power soak' my beans (if I forget to soak overnight), put cleaned dry beans in large bowl, cover with boiling water, and let stand in hot water for 1 hour. Some say to drain the liquid from the beans in measuring cup and add that amount of fresh water but I put that water in the crock pot with the beans to retain the nutrients that may have boiled out, add 3-4 cups more of stock or water to cover beans completly with liquid. Turn on low and cook for 6-8 hours or high for 3-4 hours. If liquid gets too low, just add additional liquid. With white beans I add diced onion and celery (aprox 1/2 to 1 cup each for a full crock pot) about 1 hour before serving to help season the beans.

    here is a link to the grill sargent with his navy bean and ham bone soup http://www.pentagonchannel.mil/thegrillsergeants/recipes/season2/beans/Navy_Bean_Soup.pdf

    My niece uses her pressure cooker to cook her beans for chili and her husband said that he doesn't like dry beans in chili but he can't tell the difference. She has a large canning pressure cooker but my mom is talking about getting her a smaller one for regular cooking.

    Sheila

  • RunswithScissors
    RunswithScissors Member Posts: 323
    edited February 2010

    olivia- are you asking about doing diet instead of chemo, or were you referring to sleeping?

    merilee - i did take melatonin when I was on chemo, but now I'm trying to get away from taking pills- whether drug or supplement. How are you feeling, BTW? 

    havehope - Thank you for the list of foods to try. I especially loved the part about chocolate. GREAT news!  I like my chocolate milk or hot cocoa only lightly chocolate anyway, so it's great to hear the milk will overcome the effects of the chocolate.    Now I can really enjoy my hot "moontime" beverage. 

    yellowfarmhouse- I don't cook beans much - but I have heard the rumor that salting the beans before you cook will prevent them from getting soft... maybe some of the bean experts will confirm or deny this old wives tale for us! 

  • Merilee
    Merilee Member Posts: 3,047
    edited February 2010

    Thank you for asking.

    I had my 3rd treatment today and am feeling very good. I feel very blessed to have found a great onc who gets it. They are taking very good care of me. Today marks the half way done tally for me, and I am feeling really positive about that as well.

  • olivia218
    olivia218 Member Posts: 257
    edited February 2010

    I was asking about alternatives to chemo.  Thanks!

  • RunswithScissors
    RunswithScissors Member Posts: 323
    edited February 2010

    I know that more and more women are demanding oncotype testing and even chemo sensitivity testing before agreeing to it.

  • RunswithScissors
    RunswithScissors Member Posts: 323
    edited February 2010

    A few weeks ago I was reading an old book, and saw this recipe. I must have some kind of deficiency, because this drink has been on my mind ever since I saw it. It's COMPLETELY  out of season for me, so I'll have to wait another 5 or 6 months before I indulge:

    A Veggie Juice Cocktail Recipe from "Malabar Farm":

    No added water, only the juice from
    2 bushels tomatoes
    1/2 peck of onions
    2 doz carrots
    8 big bunches of celery, tops and all, the greener the better
    3 or 4 cloves of garlic
    parsley
    bay leaves
    celery seed
    mustard seed
    S&P
    dash cayenne
    spinach optional


    "When boiled and strained it looks an tastes like the finest consomme; jellied it is wonderful in hot weather; served hot, it is a delicious clear soup.  You can drink as you orange or tomato juice. We whipped it up as an experiment and have put up several dozen bottles of it each year since then...
    The chief difficulty is to stop drinking it."  -  Louis Bromfield in 1947.

    Since this was before juicers, and maybe even before blenders, I'm guessing the veggies were just cut into small pieces first. ??  

  • apple
    apple Member Posts: 7,799
    edited February 2010

    Crunchy Poodle.. you are very inspiring.. I currently live on about an acre and grow herbs, peppers, onions, squashes and tomatoes.

    We just bought a farmette with a field that could be a little orchard.  Starting over I guess.  It's been 'unworked' for about 15 years and is tree covered.  there are raspberry bushes and I would love to see an asparagus patch pop up.

    nice thread

  • RunswithScissors
    RunswithScissors Member Posts: 323
    edited February 2010

    Apple - congratulations on your new place.   Setting up a new garden can be fun - even though the first year of "taming" is the hardest part. 

    It is so worth it, though! Having access to your own home grown food is such a blessing. So many folks in industrialized nations can't buy food of that quality at any price. 

    The homemade bread I did last week turned out good. The parts i saved for the pizza crust were the best. There is something about giving the dough time to develop that really does improve it. Slow rise is supposed to be healthier, too, but right now i don't remember where I learned that. Something about making the wheat more digestible, I think?   I'm using the no-knead recipes that NY Times published a while back. They are SO fast and easy, and the bread is so much better than anything I can buy in the local grocery store.

    I use white whole wheat, which is very mild tasting. (White wheat is a variety of wheat, like red wheat- it's not the same as  ordinary "white flour" which is  highly refined and  bleached.)  I use half  of the white whole wheat and half  unbleached flour.  Finally found a healthy bread the whole family loves.

    Yesterday the sun came out for the first time in many weeks. I made a point to stand outside and let it shine on my closed eyelids for awhile - not easy since it was only 15F degrees out there!  After tx, I find I'm much more wimpy about the cold. 

  • havehope
    havehope Member Posts: 503
    edited March 2010

    Drug  Recall - Very Serious ***

    Send to friends & family  

     CONFIRMED  BY: SNOPES.COM <http://snopes.com/>     Type in the word PHENYLPROPANOLAMINE in the search box

    All  drugs containing PHENYLPROPANOLAMINE are being recalled.

    STOP  TAKING anything

    containing this ingredient. It has been linked to  increased hemorrhagic

    stroke (bleeding in  brain)

    among women  ages 18-49 in the three days after starting use of medication

    The FDA  recommended that everyone (even  children) seek  alternative medicine.

    The  following medications contain  Phenylpropanolamine:

    Acutrim Diet  Gum Appetite Suppressant

    Acutrim Plus  Dietary Supplements

    Acutrim eMaximum Strength Appetite Control

    Alka-Seltzer  Plus Children's Cold Medicine Effervescent

    Alka-Seltzer  Plus Cold medicine (cherry or orange)

    Alka-Seltzer  Plus Cold Medicine Original

    Alka-Seltzer  Plus Cold & Cough Medicine Effervescent

    Alka-Seltzer  Plus Cold & Flu Medicine

    Alka-Seltzer  Plus Cold & Sinus Effervescent

    Alka-Seltzer  Plus Night-Time Cold Medicine

    BC Allergy  Sinus Cold Powder

    BC  Sinus Cold Powder

    Comtrex Flu  Therapy & Fever Relief

    Day &  Night Contac 12-Hour Cold Capsules

    Contac 12  Hour Caplets

    Coricidin D  Cold, Flu & Sinus

    Dexatrim  Caffeine Free

    Dexatrim  Extended Duration

    Dexatrim  Gelcaps

    Dexatrim  Vitamin C/Caffeine Free

    Dimetapp Cold  & Allergy Chewable Tablets

    Dimetapp Cold  & Cough Liqui-Gels

    Dimetapp DM  Cold & Cough Elixir

    Dimetapp  Elixir

    Dimetapp 4  Hour Liquid Gels

    Dimetapp 4  Hour Tablets

    Dimetapp 12  Hour Extendtabs Tablets

    Naldecon DX  Pediatric Drops

    Permathene  Mega-16

    Robitussin  CF

    Tavist-D 12  Hour Relief of Sinus & Nasal Congestion

    Triaminic DM  Cough Relief

    Triaminic  Expectorant Chest & Head

    Triaminic  Syrup Cold & Allergy

    Triaminic  Triaminicol Cold & Cough

    I just found  out and called the 800# on the container for  Triaminic  and they  informed me that they are

    voluntarily recalling the following  medicines because of a certain

    ingredient that is causing strokes and  seizures in children

    Orange3D Cold  &Allergy Cherry (Pink)

    3D Cold &Cough Berry

                        

    3D Cough  Relief Yellow 3D Expectorant

    They are  asking you to call them at 800-548-3708 with the lot number on

    the box  so they can send you postage for you  to send it  back to them, and they will also issue you

    a refund. If you know of  anyone else with small children,

    PLEASE PASS  THIS ON.. THIS IS SERIOUS STUFF!

    DO PASS ALONG  TO ALL ON YOUR MAILING LIST so people are informed. They

    can then pass  it along to their families.

    To confirm  these findings please take time to check the  following:

    http://www.fda.gov/cder/drug/infopage/ppa/_ <http://www.fda.gov/cder/drug/infopage/ppa/_>  

  • havehope
    havehope Member Posts: 503
    edited March 2010
    The Mathematics Of Cancer
    Robert Langreth, 03.15.10, 6:00 PM ET  Larry Norton sees some of the toughest cases as deputy physician-in-chief for breast cancer at Memorial Sloan-Kettering Cancer Center. He has access to the most advanced imaging machines, the best surgeons and numerous new tumor-fighting drugs. But often the fancy technology helps only temporarily. Sometimes a big tumor will shrink dramatically during chemotherapy. Then all of a sudden it comes back in seven or eight locations simultaneously.Norton thinks adding more mathematics to the crude science of cancer therapy will help. He says that oncologists need to spend much more time devising and analyzing equations that describe how fast tumors grow, how quickly cancer cells develop resistance to therapy and how often they spread to other organs. By taking such a quantitative approach, researchers may be able to create drug combinations that are far more effective than the ones now in use. "I have a suspicion that we are using almost all the cancer drugs in the wrong way," he says. "For all I know, we may be able to cure cancer with existing agents."His strategy is unusual among cancer researchers, who have tended to focus on identifying cancer-causing genes rather than writing differential equations to describe the rate of tumor spread. Yet adding a dose of numbers has already led to important changes in breast cancer treatment. The math of tumor growth led to the discovery that just changing the frequency of chemo treatments can boost their effect significantly.In the future Norton's theorizing may lead to new classes of drugs. Researchers have always assumed tumors grow from the inside out. His latest theory, developed in collaboration with Sloan-Kettering biologist Joan Massagué, asserts that tumors grow more like big clusters of weeds. They are constantly shedding cells into the circulatory system. Some of the cells form new tumors in distant places. But other wayward cells come back to reseed the original tumor, making it grow faster. It's like hardened terrorists returning to their home villages after being radicalized abroad and recruiting even more terrorists, says Massagué, who in December showed that the self-seeding process happens in laboratory mice. If this model works in humans, it will open up new avenues for treatment. It suggests that to cure cancer, doctors need to come up with drugs that stop the seeding process. These drugs may be different from the current crop of drugs, which are designed to kill fast-dividing cells.Among other mysteries, self-seeding may explain why tumors sometimes regrow in the same location after being surgically removed: not necessarily because surgeons failed to remove part of the original tumor but because some itinerant cancer cells returned later to their original home to start a new tumor in the same place.Norton, 62, got a degree in psychology from the University of Rochester, then an M.D. from Columbia University. For a while during college he thought he would make a career as a saxophonist and percussionist. The remnant of that dream is a vibraphone in his office in Memorial's new 16-story breast cancer center.Ever since he was a fellow at the National Cancer Institute in the 1970s he has been trying to come up with mathematical laws that describe tumor growth. He treated a lymphoma patient whose tumor shrank rapidly during chemotherapy. A year later the cancer returned worse than ever. The speed with which the tumor grew back didn't jibe with the prevailing notion that most tumors grew in a simple exponential fashion.Working with NCI statistician Richard Simon, Norton came up with a new model of tumor growth based on the work of the 19th-century mathematician Benjamin Gompertz. The concept (which other researchers proposed in the 1960s) holds that tumor growth generally follows an S-shape curve. Microscopic tumors below a certain threshold barely grow at all. Small tumors grow exponentially, but the rate of growth slows dramatically as tumors get bigger, until it reaches a plateau. A corollary of this: The faster you shrink a tumor with chemo, the quicker it will grow back if you haven't killed it all.Based on these rates of growth, Norton argued that giving the same total dose of chemotherapy over a shorter period of time would boost the cure rate by limiting the time tumors could regrow between treatments. The concept got a skeptical reaction initially. "People said it was a total waste of time," he recalls. It took decades before Norton was able to prove his theory. But in 2002 a giant government trial showed that giving chemotherapy every two weeks instead of every three lowered the risk of breast cancer recurrence by 26% over three years, even though the two groups got the same cumulative dose.

    Today Norton's "dose-dense" regimen is common practice for certain breast cancer patients at high risk of relapse after surgery. Timing adjustments are also showing promise in other tumor types. Last October a Japanese trial found that ovarian cancer patients lived longer if they received smaller doses of chemotherapy weekly rather than getting larger doses every three weeks, according to results published in The Lancet."Larry has been one of the real thinkers in this area," says Yale University professor and former NCI head Vincent DeVita. But designing better treatment schedules doesn't get as much credit as the glamorous business of inventing drugs.Norton's latest theory about how tumors grow is derived from Massagué's pioneering research. It is consistent with Gompertz's growth curves and ties together two essential features of cancer that researchers had long considered separate--cell growth and metastasis.Their collaboration started five years ago, when Massagué called Norton and shared a startling finding that was emerging from his laboratory. Massagué was studying how tumors spread from an organ such as the breast to the lungs, brain and other faraway places. He took human breast tumor cells, implanted them in mice and waited for metastases to occur. He analyzed cells that had metastasized to see what genes were overactive. None of the genes implicated in the spread of cancer to distant organs had to do with excessive cell division, it turned out. Instead, they all related to the ability to infiltrate and adapt to new environments.The finding seemed to contradict doctors' impression that the fastest-growing tumors are also the most likely to spread. Pondering how to reconcile the two ideas, Norton and Massagué theorized that tumor cells released into the bloodstream sometimes are attracted back to the original tumor and help it expand.Self-seeding may explain why large tumors tend to grow (in percentage terms) more slowly than small tumors: It could be that growth is a function of surface area rather than volume. Tumors that are efficient seeders may kill people by promoting the seeding process, not because they have a higher exponential growth rate.It took Massagué four years of work to prove that self-seeding occurs in laboratory mice. Now comes the tricky part: coming up with drugs that block tumor seeding. Massagué and Norton have identified four genes involved in seeding and are testing for drugs to block them. Convincing drug companies to go along could be difficult; it's easier to see whether a drug shrinks tumors than to see whether it stops evil cells from spreading. But Norton believes that doing this hard work may be the key to a cure.
  • Merilee
    Merilee Member Posts: 3,047
    edited March 2010

    I would propose posting a link to long articles rather than a cut and past. Just my thoughts

  • 3monstmama
    3monstmama Member Posts: 1,447
    edited March 2010

    For those who want to learn to can tomatoes, I would strongly suggest that you check your local area for classes on tomato canning or hook up with an experienced canner.  In some areas [more than you might think] local agriculture departments give lessons in canning.  Or if you live near a more rural area, check the grange or 4H.   Jam is easy because if you do it wrong, the jam simply molds.  Likewise pickles [hey you out there with too many zucchini, you know you can pickle zucchinis just like pickles!] have vinegar and don't mold and are hard to mess up.  But Canned Tomatoes are trickier ---they can be bad and you won't know it until it makes you sick.  In any case, the Ball Blue Book is a great source of information.

    Another thing to consider is just plain freezing things when plentiful.  Apricot halves, whole berries, whatever stone fruit is in season can be frozen on a cookie sheet, tucked into bags [or containers] and used with great success in mid winter.  Also things like green beans--blanch them first.

    We recently ditched most of the plastic dishes in our house.  We only had them because we had kids and, well, accidents happen. But the more I read about plastic, the less I liked it.  So we went to the local Goodwill and picked up some pottery stuff for everyone.  Each kid got to pick his own plate, bowl and small plate.  If it gets broken, who cares?

    What I have had more trouble replacing is the plastic containers we use in the kids' lunch boxes.  I can save my jars for leftovers at home but I can't send my 8 year old to school with his lunch in a glass jar.

    For those with plastic bag overload, there are instructions on the internet for how to turn those stupid things into plastic scrubbies and door mats!

  • CrunchyPoodleMama
    CrunchyPoodleMama Member Posts: 1,220
    edited March 2010

    3monst, have you seen the stainless steel lunch containers? They would work for a kid's lunch... I've seen some that were specifically for lunch boxes and they're unbreakable. Let me know if you want to dig up some of the sources I bookmarked.

  • RunswithScissors
    RunswithScissors Member Posts: 323
    edited March 2010

    Update on the Microgreens project -

    We ate these in a salad the other day, FINALLY.  And I must say it was really  delicious. Unlike sprouts, it didn't have that starchy taste. It was closer to a really excellent mesclun in flavor.  But ...

    Of course there's a but! This took forever! The seeds germinated really quickly, but then they just stalled and just would not produce the second set of leaves (except the peas - they grew nicely).

    I got really tired of moving the tray out of my way all the time. If I had multiple trays going, so we could have this frequently during the winter, it would have been a nightmare. 

    I think it will be worth the effort to produce microgreens next winter, but I will definitely set up some kind of dedicated shelving system for it, with grow lights,  so growth does not stall. 

    ONe of the key things that made it nice was the onion was SO mild. I think I will add beets for more color.   

    I read that soil scraped from the woods makes the best growing medium if you don't want to buy potting soil. (Very humusy and light, fewer weed seeds)   You collect in autumn, dampen it (to sprout the weeds), then let it dry out and use as needed. 

  • havehope
    havehope Member Posts: 503
    edited April 2010
    Happy Easter! Red Wine Helps Cardiovascular Health, But Is It the Alcohol or Something Else?Two studies show different results on the source of wine's heart health benefitsJacob Gaffney
    Posted: March 31, 2010One of the longest-running debates on the potential health benefits of regular, moderate red wine consumption is whether the alcohol or the other components in wine are responsible for better health. A study from Italy claims that moderate consumption of alcohol, regardless of other compounds like polyphenols, can help prevent a repeat heart attack. But a new study from the U.K. suggests that the polyphenols found in red wine may help keep blood vessels in proper working order.Previous studies suggest that red wine is responsible for improved blood flow, which helps keep the heart and the body in better health, but whether that's due to polyphenols or alcohol, or both, is still unclear. A study from the Research Laboratories at the Catholic University of Campobasso, Italy, claims the alcohol, not the antioxidants, helps prevent another heart attack or stroke.Published in the Journal of the American College of Cardiology, the study looked at 16,351 people from eight countries who had previously suffered a heart-related injury, usually a heart attack. When the researchers compared their drinking habits to the recurrence of strokes, heart attacks, or any other deadly cardiovascular event, they found that moderate drinkers of one to two servings of alcohol per day had a 20 percent lower risk of recurrence compared to nondrinkers and heavier drinkers."Our research highlights another crucial issue: Drinking has not only to be moderate, but also regular," said co-author and university epidemiologist Licia Iacoviello in a statement. "Moderate consumption spread along the week is positive. The same amount of weekly alcohol, concentrated in a couple of days, is definitely harmful."The director of research at Compobasso warned against using the study as an invitation to start drinking, however. In a press release, Giovanni de Gaetano said that the study dealt with previously ill people and, therefore, is not necessarily translatable to the general public.A study conducted at the University of Surrey, England, published in the Journal of Human Nutrition and Dietetics, suggests that alcohol may not be the only factor, however. A research team found that people who drank a kind of simulated wine—alcohol mixed with red grape juice—during mealtime showed several markers of improved cardiovascular health. Those who drank just water did not see the same levels of improved blood flow. Those who drank just grape juice saw slightly lower benefits.To try to figure out the relationship between alcohol versus red wine compounds, the team had ten subjects consume a standard meal with a test drink on different occasions. The test drinks accompanying the meal were either water, red grape juice or red grape juice plus alcohol. Red wine itself was not used in any form, as de-alcoholized wine tends to still contain some level of alcohol, which might have marred the results. The simulated wine was red grape juice with alcohol added to create a 12 percent alcohol drink. Various measurements were taken to estimate blood flow.The flow-mediated dilation, a measure of the ease at which blood is pumped through the body, stood at 6 percent for those who only had water, 7 percent for those who had grape juice only and more than 8 percent for those who had the red grape juice/alcohol mixture.The scientists credit ingredients in the red grape juice for most of the benefits. "The conclusion drawn from this study was that non-alcoholic components present in alcoholic beverages have a potential benefit on vascular function—blood vessels," said Dr. Shelagh Hampton, senior research fellow on the faculty of Health and Medical Sciences.
  • thenewme
    thenewme Member Posts: 1,611
    edited January 2011

    Bumping this thread because I have a green-living question and a tip!

    I used to scrape the soap scum/hard water deposits from the shower, but I've discovered a true miracle!  Magic Erasers  - they're sponges that really, actually outperform their claims!  No more scrubbing, chemicals, scraping, etc - the soap scum really just wipes away - easily!  Seriously! It even works great on the textured refrigerator door handles that never would look clean.  Or the grimy greasy-dust covered back of the range!  I feel like a commercial advertisement, but I love these things!

    Question for those who compost - any recommendations for a decent-looking compost container for the kitchen countertop?   No room under my sink, and it only matters when it's too cold/snowy to trek out to the compost bin.  I've been using just a bucket, but it looks so tacky, and I don't want to spend $40 on the pretty "crock" style ones I've seen online.  I'm crafty, so I could make something, but I'm at a loss as to what would work best. Ideally, I'd prefer something that uses compostable bags to ease the yuck factor.  Any suggestions?

  • MariannaLaFrance
    MariannaLaFrance Member Posts: 777
    edited January 2011

    All-

    You are inspiring me! We live on 1.5 acres, and I attempted a grow box garden for the past two years, but I had pests the first year (refused to use any pesticides and my vegetation died), and last summer, well, I had just been diagnosed with cancer, and gardening wasn't on my priority list. I will start again this spring. We live in Texas, so our summer cuts our growing season short with the heat.

    Changes we have made? Well, my diet has radically changed, but I was fairly organic before. However, I have stepped it up a notch, because I truly get 8-10 fruits and vegetables a day, and if I don't I have a multi-vitamin to back it up. But most days, I do pretty well. I have 3 small children, so I cannot avoid Sams Club or Costco, so I stock up on beans there (not organic, unfortunately-- can't do all organic due to cost). Once a week, I do pinto beans with onions and seasoning. Pretty yummy, and we have that to nosh on during the week.

    I buy lots of produce at Sams and Costco-- organic where possible, and I don't worry if it's frozen. I buy organic frozen fruit (berries, mangos, etc) as well. I buy the bulk produce and fruits, since there are 5 of us.  Then I go to Whole Foods for organic meats and dairy.

    I don't consume dairy anymore (unless it is cultured), so I've replaced cereals in the a.m. with etiher quinoa or flaxseed waffles with a bit of almond butter. Or organic eggs if I have time. I also do not consume wheat products of any sort. Seems I am gluten intolerant, so I have sadly given up breads-- only have Udi's on occasion, which is a rice based bread.

    We have always composted, and I have used vinegar for cleaning for a long time. I used to use Dr. Bronners years ago, and it used to be CHEAP. Now it's pretty pricey, so I buy it and use only small amounts for cleaning my wood floors and cabinetry in the kitchen.  We use plain old bleach for the nasty stuff in the bathroom, but my husband handles it for me so I don't have to handle it at all.

    One thing I've noticed is that I started developing a strange chemical aversion for approximately 2 years prior to BC diagnosis. That is, I loved perfume for a long time, but suddenly a lot of fragrances gave me instantaneous headaches when I applied them. Candles with scent did the same thing! I am certain it has everything to do with my BC diagnosis, and have attempted to clear my environment of as many fragranced things as possible. Anyone else have this? I had to get rid of all my favorite perfumes! Frown

    I am working on a few things now: Since we live in Texas on a creek, we have SO MANY mosquitos. I've tried eating garlic, all the "natural" types of sprays on the kids and me, and nothing seems to work. My husband is not bothered by them at all, but I get bitten by swarms the moment I step outside (May through October!)  Any tips for this??? I don't like applying DEET to my kids, but sometimes I think it's better than the bites.

    I haven't used plastics for storing my food for years, and we don't use the microwave very often at our house. In fact, I have considered getting rid of it. I might just do that in 2011.

    Thank you again for starting this thread! This is a great topic!!!

  • hlth4513
    hlth4513 Member Posts: 267
    edited January 2011

    thenewme-

    I discovered the Magic Erasers a couple of years ago - they are terrific - unfortunately I have since found out that they contain formaldehyde. Back to elbow grease for me. :(.

    Beth

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