bio-identical hormones
Comments
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Jelly,
This ob-gyn did a review of the studies on breast cancer patients taking hormones.
http://www.obgmanagement.com/pdf/1406/1406OBGM_Article1.pdf
We rock!
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mollyann,
here is the link...it was down the page on the link ruthbru provided...but I am with you...get back to the BHRT!!
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mathteacher ~ Thanks for that very interesting article. If you or anyone finds anything similar dated later than 2002, I'd love to see it. I'm also wondering if anyone would be interested in calling the professor who wrote that piece, to see if he has any updated info? I'd volunteer, but I'm far from the expert on this that some of you are. Deanna
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Well we know that the WHI did a study and then halted their research on synthetic HRT. It is known to cause cancer.
Here are a few links which may help.
http://www.womenshealthnetwork.com/library/breasthealth.aspx
http://www.thewileyprotocol.com/blog/blog1.php/prempro-synthetic-hormones
side effects of synthetic hormones, and may I add that BHRT does not have these side effects
http://www.livestrong.com/article/38211-side-effects-synthetic-hormones/
http://www.lifetoolsforwomen.com/w/natural-hormones.htm
a few sentences from this next link...
Bio-identical hormones had been in use in Europe for fifty years...and...
Recent articles in the Wall Street Journal and USA Today confirmed that women are increasingly turning to bio-identicals -- as many as two million may be using them now. But the battle to make sure women have access to the best and safest hormonal therapy is far from over. -
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Claire in Seattle....as it turns out my oncologist who is in the only group in town offers chemo to everyone, opposed me having the OncotypeDX test and mentioned that she was worried about being sued in a few years if she doesn't recommend certain things. She insisted that I not do the Oncotype test and that I do chemo. I got a zero on the Oncotype test. No reasonable oncologist would recommend chemo for me but my onco would have had me do it for no reason.
Sooooo to suggest we consult our oncologists assumes they all know more than we do. She didn't tell me anything I couldn't find out for myself including AdjuvantOnline. Without doing hundreds of hours of research, we can't know if we trust our oncologists or not. If I had not done my research and followed the links suggested by the wonderful women on these threads, I would not have known that my oncologist is not to be trusted with my life. I suppose I don't really need a new oncologist unless I get cancer again since my Internist does more cancer marker bloodtests than my onco and he understands the importance of D3 which my onco has no clue about. If I ever need an oncologist again, I don't know how to find one I can trust with my life. It seems many practice a one size fits all defensive medicine protocol. I would have probably died from anger if I had followed the recommendation to do chemo only to find that it was totally unecessary and of no benefit to me.
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I have a question about hormone therapy and the claim that estrogen and progesterone are out of balance and that causes BC.
Your estrogen and progesterone balances change continually during your monthly cycle. Multiple resources on line show the variations monthly in hormones.
How do you know when you need the hormones? Or do you take them a few days before your period? How do you know when to test them? At their highest or lowest? Before or after your period? One hormone is dominant before your period, and one is dominant after your period.
If you take them everyday you would definitely be feeding your body a surplus of hormones which would stimulate the ER/PR growth of cancer cells.
I am post menopausal. Where does that leave me?
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Deanna, I don't see that matters whether the ob-gyn's article was written in 2002 or 2009. What matters is that the hormones didn't have any negative effect in any of the studies he reviewed.
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Nan, here's a 10 minute video of Dr. Elizabeth Vliet to add to your prohormone references. Somebody posted it. Can't remember who but I bookmarked it. She is great at busting myths! Oprah should have her on.
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Wow, Luna, your post gave me chills.
Your oncologist doesn't realize that she could be sued for giving chemo to a patient who doesn't need it. If you went into the hospital for a chemo-caused white blood count and died of infection your family could sue. Also, you're right. Some people get PTSD from chemo and the ordeal of dealing with these doctors in authority.
The people who stop by this forum and leave quickly don't know that you can actually read up the original research on breast cancer and the related issues. They think going to a chart on the internet is enough! These charts have individual authors. They leave out huge factors. Use the wrong stats. And have disclaimers saying this information may not apply to you.
I'm so envious that you are in Seattle. You may have heard of the Marc Gignac in your area, the Naturopathic oncologist? I've never met him but his patients love him.
http://www.seattlecancerwellness.com/naturopathic_oncologists.html
PS - I don't know whether Gignac is up on hormones but Dr. Jonathan Wright from Suzanne Somers' book is up on hormones and has his own book out. He's in your area too. Sheesh, I may move to Seattle.
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Just two more articles on BHRT, and they are from Life Extension. I believe that we all need to have a hormone panel done when we are teenagers, just for a baseline, and then every few years after that. Even young teenagers have hormonal problems, but of course conventional medicine would rather prescribe an anti-depressant. I would bet the farm that ADD is a hormonal imbalance.
PS....Lucy, thanks for that video.
http://www.lef.org/magazine/mag2009/oct2009_The-Unscientific-Bioidentical-Hormone-Debate_01.htm
http://www.lef.org/magazine/mag2009/oct2009_Bioidentical-Hormones_01.htm
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Nan, Thank you for all the great info you've provided. I feel well equiped to inform my breat dr. about my decision to go back on my bio's.. I sure wish I would have known about this site months ago. After much prayer I just stumbled across this. It's amazing how GOD answers prayer!! Again, thanks and God bless, Robin
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Dear Robin,
Here is a link for antiaging specialists in the US. This one is located in Philly, but just click on the map to find one where you live.Most conventional doctors will not "allow" you to take BHRT, even though they have no knowledge about BHRT. And...as my daughter says.."It is not my responsibility to educate them".
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Math Teacher,
Thanks for posting the study!!
WooHoo!
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Another link and this is on Dr. Lee
http://www.johnleemd.com/store/hbh-081001.html#breast_cancer_profile
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I've only read one Suzanne Somers book - Knockout. While she shares small spots of her own opinion, the book is a collection of lengthy interviews with established doctors having very good success with various kinds of cancers in an alternative setting here in our country. I can't comment on her other books, but this one is impressive in it's clarity and diversity of doctors. I'm appreciative of her guts in putting it together. She has so much info collected in that single book that it really got me down the road a ways in understanding prevention and focus related to cancer. Unfortunately, she is often so ditsy that many won't read this helpful book.
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Risk factors for breast cancer:
Women who have had more menstrual cycles because they started menstruating at an early age (before age 12) and/or went through menopause at a later age (after age 55) have a slightly higher risk of breast cancer. This may be related to a higher lifetime exposure to the hormones estrogen and progesterone.
Not having children, or having them later in life
Women who have had no children or who had their first child after age 30 have a slightly higher breast cancer risk. Having many pregnancies and becoming pregnant at a young age reduce breast cancer risk. Pregnancy reduces a woman's total number of lifetime menstrual cycles, which may be the reason for this effect.
Using post-menopausal hormone therapy
Post-menopausal hormone therapy (PHT), also known as hormone replacement therapy (HRT) and menopausal hormone therapy (MHT), has been used for many years to help relieve symptoms of menopause and to help prevent osteoporosis (thinning of the bones). Earlier studies suggested it might have other health benefits as well, but these benefits have not been found in more recent, better designed studies.
There are 2 main types of PHT. For women who still have a uterus (womb), doctors generally prescribe estrogen and progesterone (known as combined PHT). Because estrogen alone can increase the risk of cancer of the uterus, progesterone is added to help prevent this. For women who no longer have a uterus (those who've had a hysterectomy), estrogen alone can be prescribed. This is commonly known as estrogen replacement therapy (ERT).
Combined PHT: Use of combined post-menopausal hormone therapy increases the risk of getting breast cancer. It may also increase the chances of dying from breast cancer. This increase in risk can be seen with as little as 2 years of use. Large studies have found that there is an increased risk of breast cancer related to the use of combined PHT. Combined PHT also increases the likelihood that the cancer may be found at a more advanced stage, possibly because it reduces the effectiveness of mammograms.
The increased risk from combined PHT appears to apply only to current and recent users. A woman's breast cancer risk seems to return to that of the general population within 5 years of stopping combined PHT.
ERT: The use of estrogen alone after menopause does not appear to increase the risk of developing breast cancer significantly, if at all. But when used long term (for more than 10 years), ERT has been found to increase the risk of ovarian and breast cancer in some studies.
At this time there appear to be few strong reasons to use post-menopausal hormone therapy (combined PHT or ERT), other than possibly for the short-term relief of menopausal symptoms. Along with the increased risk of breast cancer, combined PHT also appears to increase the risk of heart disease, blood clots, and strokes. It does lower the risk of colorectal cancer and osteoporosis, but this must be weighed against possible harm, and it should be noted that there are other effective ways to prevent osteoporosis. Although ERT does not seem to have much effect on breast cancer risk, it does increase the risk of stroke. The increased risk of hormone replacement therapy is the same for "bioidentical" and "natural" hormones as it is for synthetic hormones.
The decision to use PHT should be made by a woman and her doctor after weighing the possible risks and benefits (including the severity of her menopausal symptoms), and considering her other risk factors for heart disease, breast cancer, and osteoporosis. If a woman and her doctor decide to try PHT for symptoms of menopause, it is usually best to use it at the lowest dose that works for her and for as short a time as possible.
Not breast-feeding
Some studies suggest that breast-feeding may slightly lower breast cancer risk, especially if breast-feeding is continued for 1½ to 2 years. But this has been a difficult area to study, especially in countries such as the United States, where breast-feeding for this long is uncommon.
The explanation for this possible effect may be that breast-feeding reduces a woman's total number of lifetime menstrual cycles (similar to starting menstrual periods at a later age or going through early menopause).
Being overweight or obese
Being overweight or obese has been found to increase breast cancer risk, especially for women after menopause. Before menopause your ovaries produce most of your estrogen, and fat tissue produces a small amount of estrogen. After menopause (when the ovaries stop making estrogen), most of a woman's estrogen comes from fat tissue. Having more fat tissue after menopause can increase your chance of getting breast cancer by raising estrogen levels.
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Take hormones if you want. But realize that you are increasing your risk of a primary breast cancer or recurrence by doing so.
All these factors are about exposure to your body's own estrogen, which is what bio-identical hormones are *supposed* to replicate.
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Anon: I had NO IDEA there was a "naturopathic oncologist" somewhere in the world. WOW! Yes, I may move to Seattle as well!
Thanks for the link.
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If anyone IS interested in checking it out, the website is adjuvantoline.com
Julie
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First I'd like to say to those who fear that we on this alternative forum will come to some harm through the use of unconventional treatments, please know that the women on here have researched, discussed and debated and don't take the word of any one person or web site without looking up other sources and making comparisons etc. It seems to be our questioning minds, intelligence and independence, along with the knowledge that medicine does not have the answer to cancer, that spurs us on to find alternatives and complementary treatments. Please feel free to correct me or add to this if I am in any way off base as I have only followed this CAM forum since last July.
Adjuvant Online data is the number of women who have been estimated to have a recurrence or survive after 10years out of 100 so it is definitely absolute, not relative.
The problem for me with Adjuvant Online is that it never states the source of the women who have not had chemo when comparing them to those who have had chemo. I assume they use all women who have entered any research but it would be unacceptable to give women a placebo in place of chemotherapy so they don't seem to have an acceptable base of untreated women for comparison. Using data from before chemotherapy was introduced would not work as they had more women at a later stage due to less sophisticated diagnostics and less BC awareness among women. Stages have changed and the knowledge of the status of lymph nodes, estrogen positive or negative, HER2 etc has changed so much since the days before chemo came on the scene. All the studies I have seen compare existing treatments with new drugs or combinations.
There were several statistical problems that I put to my oncologists when trying to decide whether to have chemotherapy and later when I wanted to stop chemotherapy during treatment and they could not answer except to reiterate their faith in the figures. I even took my university student son along as he was in the second year of a maths degree. He played around with Adjuvant Online at home but his bias was towards mathematical modeling without knowing where the sources came from.
This does not give me faith in the medical system or their statistics, along with the fact that my sister was once close to death after 3 days in hospital with a misdiagnosed ectopic pregnancy and my husband was twice misdiagnosed when he had immediate life threatening illnesses. I now look into all suggested treatments before making any decisions that could cost my or my family's life or quality of life. I personally would not take BHRT without a lot of research but I trust these women to make the right decision for them and to know the risk they are taking.
Edited to add the word 'once' in the last paragraph.
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According to my doc, adjuvantonline is not reliable because it never factors in the 20%-30% placebo effect of the separate treatments.
And you're right about not having an acceptable base of untreated women. I looked into that. Many women who refuse treatment have other diseases, e.g., diabetes, cardio, lung, etc. I got an estimate that only 5% of healthy women refuse treatment-- but that is only an estimate-- and they are not followed. They have followed Arimidex takers/nontakers however and there isn't any clear overall survival advantage.
Also, the mixing and matching of combined treatments screws up identifying whether any single one actually works.
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Tic, it is important to understand that AdjuvantOnline utilizes a somewhat limited pool of statistical data. Oncologists put a lot of stock into AO, but only because they don't have any other option really. But understand that the numbers which are given to patients are not bullet proof; they refer to general statistical numbers only. For example if a drug study says that 2 out of 100 patients experienced no recurrence within five years of a particular type of chemo, whereas it would have been 1 out of 100 patients without said chemo, they can state that there was a 50% benefit with that chemo protocol; another version of statistics can even state that there was a 100% benefit with that protocol. When I was researching and meeting with different oncs, I learned that the data from AO from which all recommendations were being made to me was NINE YEARS OLD! I had a friend, a nurse, who had metaplastic triple negative breast cancer, stage 1. It was recommended in the highest order that she begin chemo based on the numbers from AO. After she peeled back the layers by looking at the actual studies from which the AO numbers were drawn she learned it was based on 27 cases of metaplastic (not metastatic) tnbc. Only 27. Plus there was no correction for life style factors or vitamin D levels. She had already had one treatment of A/C at that point. She withdrew from chemo however. She also did not do radiation, again, after pulling back the curtain on the numbers. Her Rad Onc told her she would have a 30% increased risk of local recurrence without rads--but she re-deciphered the statistics and learned it was actually 2-3%, and again, opted out of rads. She is 5 years NED this year. I guess the bottom line here is that none of us should delegate our life decisions to an anonymous computer program, let alone any oncologist or doctor who in this day and age can only practice defensive medicine.
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Dear Claire:
Suzanne Sommers is not lucky to be alive. She made a focused and educated treatment choice. That is the problem with leaving the mainstream.....if she had done chemo and remained NED after 10 years, she would have been wise; done chemo and recurred, she would be unlucky; skipped chemo and recurred, a fool; skipped chemo and not recurred, only LUCKY? I disagree. She avoided the health damaging affects of chemo and came out the other side, shiny, vibrant and cancer free.
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Good Morning, this bio-identical hormone discussion is very interesting. It makes perfect sense to me that after testing your levels of specific hormones, one could potentially supplement the deficient ones and then present with levels consistent with a healthy balance. I understand thousands of women are doing this and there is a lot of evidence that it is successful. I hope this continues to be the answer. However, I would like to know, do they actually have double-blind studies by accredited facilities to test the efficacy? I believe this is the only way the medical profession/FDA would be convinced and give it credence. Even if it is successful by many and published, I think it is considered anecdotal without the certified studies. Thank you.
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Julia,
There have been more than 20 "observational" studies on breast cancer patients taking hormones after diagnosis.
An observational study is where they look a group taking hormones and compare them with the group that took no hormones and observe if there was any more recurrence and survival in one group over the other.
NOTE: There have been no double blind studies on breast cancer patients taking hormones just as there have never been double blind studies on chemo or radiation. The chemo and rads studies have also been "observational."
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There seem to be many clinical trials complete and ongoing on Taxotere, Cytoxan (my chemos) and radiation according clinicaltrials.gov. Don't mean to be confrontational, just saying... I''m wondering, does anyone know why they have not done these trials on bio-identical hormones? Thank you.
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Count me in on the bhrt, but I am triple negative, which makes the choice a bit easier, at least for now. I see a doctor who not only believes it is a quality of life issue, but had read all the studies and determined that balanced hormones, in association with nutritional management of the negative estrogen metabolites, will decrease risk of recurrence. Further to this, the truth is that there are only 8 to 9 researchers in this whole country that are experts on the estrogen/progesterone pathways and how they affect our primary cancer risk and recurrence risk. Even they don't understand the entire model. But I know that if you are starved of hormones you may still have recurrence and your quality of life is poor and suffers. The healthiest time of our adult lives takes place in our twenties, and guess what, we have an abundant hormone presence during that time. It made me wonder.
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My Onc is on board with me trying balancing my hormones but does not know much about it. She has agreed to help me find someone in the area that can advise me. Can you ladies offer a list of questions I should ask?
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Dear Merilee,
Here is a link for bio-identical doctors. Just fill out the form and they will send you a list of doctors in your area for Michigan.
http://www.bioidenticaldoctors.com/Michigan.html
You must find a doctor who is willing to work with a woman who was dx with BC.
I would recommend that you buy the book by Dr. John Lee..."What your doctor may (not) tell you about breast cancer". I purchased 6 copies for $5.00 on Amazon. I am not getting a kick-back by telling people about this book. You really need to read this and gather all the info that you can BEFORE seeing an anti-aging doctor. Not all anti-aging doctors have the expertise to properly prescribe exactly what you will need. Also the blood tests are really not accurate. You need saliva testing to determine what you need.
My daughter Lori was dx with TNBC in June of 2007, and has been on BHRT since June of 2009. She could not live without them. MsBliss is so right...this is a quality of life issue, and most conventional doctors know little to nothing about BHRT, and will only prescribe the synthetic HRT. Kudos to your doctor for caring about you!!
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