Chemotherapy?

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brynze
brynze Member Posts: 35

Can someone explain what this may entail for me, and the potential side effects if possible? I was diagnosed with IDC & DCIS. One doctor said it was @1cm Stage 1, and another said around 2cm - closer to Stage 2... They did not test the ER/PR on the biopsy specimen... My new Surg Onc is sending out for that. Most think it will be ER positive though because I now tested BRCA2 positive too. I have been told by three doctors that mostly because of my age (35), I will be put on chemo regardless...? They view earlier cancers as more aggressive for some reason. And because of testing BRCA2 positive I guess. Also that my aunt & grandmother died in their thirties (breast/ovarian cancer-we aren't positive which hit first).

 I'm assuming it would be a low dose of whatever kind of chemotherapy...?

 Any help with what that treatment might entail - I get confused when people mention what sounds like drug names when talking about chemo... Also, how much more time out of life does this take? Are you ever the same after Chemo?

Thank you so much!

Comments

  • Mamita49
    Mamita49 Member Posts: 538
    edited June 2009

    Just be carefull what docs say BEFORE surgery. Only AFTER surgery they can tell the size of your tumor, and SNB will tell if you have lymph nodes positive or negative, It all depends on the path report.

    Standard treatments depend on node involvement and tumor size, ( Which means wich stage you are...)Usually you will have every 3 weeks a round of chemo After surgery, usually 6-8 cycles of medication.

    Yes, ------- it will change your life, you will not be the same ever anymore, BUT, it depends on you HOW you change your life, if you see the Chemo as your medication that will save your life, OR if you see the Chemo as a toxic enemy.

    Myself, I see chemo as a bump in my life, to get rid of microscopic cancer cells. I imagine this and see the treatment as something helpful.

    God luck 

  • brynze
    brynze Member Posts: 35
    edited October 2009

    Well, I don't see it so much, becasue this is all happening so fast, and previously

    I expected a simple lumpectomy w/radiation. Then I came back BRCA+ and everyone

    is saying my safest bet is a mastectomy - and I was unhappy with the breast center

    that diagnosed me (was told there firmly I would not need chemo to boot), and ended up meeting with a few others. I consistently now hear from every other doctor that I'll most likely be put on chemo regardless...??? :(

  • Anonymous
    Anonymous Member Posts: 1,376
    edited June 2009

    bizzlin- I was 44 at diagnosis -no family history but the surgeon recommended that I have the brac1/2 testing as they considered me to be on the young side.  They also said that if the test were positive, they would recommend mastectomy - if it were negative, lumpectomy.  So, that must be your docs opinion as well.

    As far as chemo, I think that depends on a few things.  However, your young age and BRAC status would make a lot of oncologists recommend chemo automatically- I think.   Oncotyping could give you more info.  I can't tell if you have had surgery or not.  

    Hang in there - you are at the hardest part of this - dealing with the overwhelming info and waiting for more info.  Once you have a plan it seems like it is a bit easier to deal with.

    April

  • nelia48
    nelia48 Member Posts: 539
    edited June 2009

    There are different chemos, and it depends on the type of cancer you have the positive or negative type, etc., as to what you will get.  I had 6 treatments, 3 weeks apart, so that's about 18 weeks out of your life.  I felt like roadkill those 18 weeks, but afterwards, I came back pretty fast.  I then had the mastectomy and then the radiation.  Each thing was hard, but I bounced back, and I'm 60 years old.  There is no way you can think of the whole journey and wonder if you can make it.  It has to be one step at a time, one day at a time.  I'm telling you, I NEVER in my wildest dreams thought I could do ANY of this.  But I did.  And if I can do it, anyone can make it through.  Please don't let your fears stop you from getting the treatment you need.  And me??????  With your family history, I'd take all I could get!

  • Anonymous
    Anonymous Member Posts: 1,376
    edited June 2009

    Nelia - I completely agree and feel bad that I didn't mention that chemo is not as bad as it would seem.  Great advice to not let your fears stop you or worry you to much.  The fear of chemo is so much worse than the actual treatments.  Yes, it sucks (can I say that here?) but hitting it hard from the start is a great idea.

    Nelia, I have to say I always like your posts - you have a wonderful attitude and way with words!

  • Estepp
    Estepp Member Posts: 6,416
    edited June 2009

    I was 40 going through Chemo.. 16 total treatments... I was told I would never be the same. This scared me.

    I am not the same... I am BETTER!

    I am not the same inside.. I feel I am softer.. mellower.. happier..etc....

    My body is getting back. I am back in the gym and feeling good.

    You WILL be the old you if that is what you choose. Or you will be a little different, if that is what you choose.

    I believe it is a choice.

    Your call sister!

    You CAN do this!

    Love!

  • Titch
    Titch Member Posts: 141
    edited June 2009

    Hi, I am 36. I was diagnosed April 29 and started chemo May 12th as my cancer is agressive. Clinical - Stage 3 and ultrasound measure my cancer at 5.5 cm (doubled in 2 months from when I had my first ultrasound pre diagnosis). They also identified in ct scan - in 2 nodes. I have just had my second session of chemo. I have had minimal SE from the chemo so far. Besides being tired a week after my first session, and taste buds out of hilt and losing hair. But since I had my second session, no SE at all (except the hair). My masectomy was scheduled for may 18th but postponed until I completed 4 sessions of chemo. I am still working full time, and maintaining a family (3 kids and hubby) I only have treatment days of work. I feel very well.

    In 3 weeks my cancer has stopped growing and already shrinking - with the chemo.

    of course there is lots of different chemo drugs and SE can affect everyone differently. They try and prescribe the SE drugs to make u manage the nausea, and other SE, whilst some struggle with the chemo, some don't. We will have our own experience.



    Have trust in your specialist that they will work out the best treatment plan for you, and your cancer. They will monitor and change things that they think need too as you progress thru your treatment plans.



    My intial plan was masectomy, chemo, radiation, hormone treatment. (possible herceptin)

    Then changed to Chemo, masectomy, more chemo, radiation and hormone treatment (possible herceptin) - Only changed as they want to stop the growth of the cancer. The positive of having chemo pre surgery - is that they can see how the cancer responds to the chemo. After a masectomy they use chemo / radiation to stop the spread of cancer cells, but as the cancer is already removed they do not really know if the cancer cells is responding.

  • brynze
    brynze Member Posts: 35
    edited October 2009

    Hi All-

    Thanks so much for your responses! Means a lot right now...

    I haven't had surgery yet - I'm struggling there. I was given four to six weeks initially (on April 27th), so clearly I'm about to the end of that... However, a lot has gone on in between, including just this past week taking meeting to find a new surgical oncologist. A lot of mistrust in where I was first dx, wasted time with doctors who weren't going to be right for me, and clearly trying to wrap my head around a mastectomy. I went from about to schedule my lumpectomy to being advised to have a mastectomy, which I have not dealt well with. I also have a crappy limited insurance - am unemployed - and just really stressed out...

    Being told about the potential ovary problem around the corner also since the BRCA2+ dx...Being advised to freeze my eggs now because I will most likely need chemo. Doctors trying to sell me on their reconstructive wants. Feeling very unheard...

    Again I went from thinking I'd have a lump w/rads - to being advised to have a mastectomy - and now also being told regardless I will probably have some chemo  due to age, gene status, fam hist...

    While my aunt and grandmother both died in their thirties... I believe this was at a time that less was known. My grandmother clearly... And she was pregnant when they found her cancer, so there wasn't much the doctors could do. My aunt who then also died in her thirties, is who my grandmother was pregnant with... That was at least thirty three years ago that my aunt died - i didn't know her - and have to believe also she was either dx too late (with much poorer imaging detection then). Er, possible she didn't have had the best doctor team ;) dunno. i do know whatever she had or was found with first- she lived a good 3-5 years maybe going through treatment, etc... But my family didn't really talk about it, so no one knows if it was the breast cancer first, or ovarian - how it started - stage etc... - and how it grew too big to be saved...

    Anyways - to be told I may need chemo now is daunting - But I am assuming it will be the lowest dose considering my dx - and their guessing it is ER/PR positive, etc... So anyone have any idea what I could be up for, and how a lower dose chemo may effect me, if that makes sense?

    :(

  • AlaskaAngel
    AlaskaAngel Member Posts: 1,836
    edited June 2009

    Bizzlin

    I am generally not terribly supportive of chemo for those who can possibly benefit from hormonal treatment instead. You won't know that until you get your final pathology report. But to answer your question, the dose given isn't less for smaller tumors. The only type of chemo regimens given that use a smaller dose is sometimes for the elderly or those with other health conditions that would not support the common dose, other than the less commonly given chemotherapy that is given daily instead of periodically (metronomic chemotherapy).

    There have been many in my family with bc, and one with OC but none were young. I wish I could give you more encouragement about the choice of treatment. 

    AlaskaAngel

  • lemont
    lemont Member Posts: 31
    edited June 2009

    Bizzlin,  

    It's not generally the dose that changes, it's the combination of drugs and the number of treatments. There are many different combinations. The medical oncologist chooses the combination based on the pathology of your specific cancer, so you won't know for sure until your pathology report comes back after surgery. The NCCN publishes the guidelines (www.nccn.org).

    I know it is hard to make so many decisions, but I hope you will proceed soon. You'll have a lot more info after surgery and it sure helps to have a better idea of what you're dealing with. It may help to know that you do not have to decide on reconstruction now. It can be done any time.

    My best to you, Cinda

  • GramE
    GramE Member Posts: 5,056
    edited June 2009

    The thing I found most helpful was to concentrate on what chemo did ---  and NOT the side effects.  They ALL have side effects and can usually be controlled.   And chemo is not forever, although some days it will seem like it.   I had a total of 16 chemo treatments over the course of 3 months.  Dose dense chemo and it shrunk my tumor to nothing.   Trust your doctors, ask lots of questions.  It is NOT dumb to ask, it is dumb NOT to ask.   

  • swimangel72
    swimangel72 Member Posts: 1,989
    edited June 2009

    Since you are so young and BRCA positive - you should check out the following web site which offers so much help for young women like you:

    http://www.facingourrisk.org/

    I can identify with you regarding the SHOCK of hearing that chemo would be necessary! I was led to believe by my breast cancer surgeon that since I chose a uni-lateral mastectomy with my small .9 cm Stage 1, Grade 1 tumor - and since I was post-menopausal, I'd be sent on my way with just a anti-estrogen drug (Arimidex). Surprise -surprise - my FISH report comes back showing the tumor was Her2++++ and I needed chemo for 4 months, and Herceptin every two weeks for an entire YEAR! Then - I was told - I needed surgery to implant a port! On top of this, I was in a weakened emotional state after getting MRSA in my abdominal incision after my immediate free-tram reconstruction. Still - as  much as it was a HUGE HUGE blow to my mind, body and soul, I prayed and prayed and came here to bc.org for support and made the decision to trust my oncologist (who was a very kind man). I finished the chemo last July 2008 with very little side effects...........and I finished the Herceptin this past April - and life is looking very good to me now.

    You CAN get through this.........it takes a lot of research.........and trust......but you will get off this roller-caoster ride and continue with your life. I'm sorry about your insurance issues - and hope the web site I posted above can give you further help. Hang in there - I'll be praying that God's angels watch over you during this extremely difficult time!

  • pshelton
    pshelton Member Posts: 140
    edited June 2009

    Bizzlin,

    One of the reasons I have to have chemo is my age and it is true when BC strikes young it is usually a more aggressive form according to research, they are not sure why.  It was harder hearing that I had to have chemo than hearing the words breast cancer or mastectomy but I am doing better now thinking about it.  It will insure a better outcome for me, I know that.  Ask them which chemo agents they are planning on giving.  Also, ask if they are cardiotoxic as some of them are which means they cause heart failure and/or cardiomyopathy.  My oncologist chose two forms of chemo for me that are NOT cardiotoxic because of my age.  I have prescriptions to pre-medicate prior to treatment and for after treatment to control the nausea, vomiting and diarrhea.  I also have a prescription for ativan in case I have anxiety due to the treatments.  

    Now I just have to get my courage up to go wig shopping, I tried once but cried too much, might be ready now and may give it a try next week.  

    The size of your mass also comes into play regarding chemo, mine was 2.0 x 1.0 x 1.0 and I had a second that was 1.0 x 1.0 x 1.5.  I had 5 primary sites including those two and one secondary site. I am BRCA negative.  Her2neu negative but ER/PR positive.

    Hope this helps some...wishing you the best, sending prayers your way, Paula 

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