What's in store for our young daughters?

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pinkshortcake
pinkshortcake Member Posts: 31

It's not something I want to think about, but I'm sure it has crossed the minds many times of those of us diagnosed and have young daughters.  My Isabella is only nine years old, but I am scared for her.  There was no history of breast cancer in our family, but my mother passed away of colon cancer at the age of 41.  My BS suggested that I start testing Issy at the age of 18.  Just curious if anyone else has any more info regarding that.  Thanks!

Lori

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  • ElaineD
    ElaineD Member Posts: 2,265
    edited April 2009

    Lori-have you been tested for the gene misprints yet? It would be a good starting point for you-if you test negative, then effectively Isabella will be at no higher risk than the population in general. Admittedly there are new genes being discovered, but as a rough rule of thumb, if you are negative, then her risk factor will be the same as the rest of the population.

    If you've done the test, and it's positive, then you do have more of a dilemna. I'm BRCA2-as is my daughter and several of my cousins. She was tested at age 21-which in the UK is seen to be as early as the geneticists like to do it-and for various reasons, they would actually prefer to leave it until the child was older. There's very little accurate monitoring that can be done at present until about the age of 30-so a positive diagnosis earlier, can potentially cause a huge amount of stress.

    But forever the optimist...genetics is such a rapidly evolving field, that it doesn't seem unrealistic to hope that in 20 or so years (by which time your daughter could start to be monitored if she does have a gene misprint), then who knows...it could be, if not curable, then a much more manageable disease.

  • lexislove
    lexislove Member Posts: 2,645
    edited April 2009

    I worry too. My daughter is only 3. I was diagnosed at 30...so I guess she will have to start mammograms at age 20. I sometimes feel so guilty, that she will have to worry and might be in fear. I hope she doesn't blame me for anything.

    My only hope is that there will be some vacine for prevention or even a CURE! My plan is to make sure she can live a healthy active lifestyle to help prevent anything. I have no BC in my family either.

  • everyminute
    everyminute Member Posts: 1,805
    edited April 2009

    I have a 16 and 14 year old (girls).  I am scared silly for them.

  • EWB
    EWB Member Posts: 2,927
    edited April 2009

    Please do not forget your sons! They will also be affected, their risk will also increase.

  • Deirdre1
    Deirdre1 Member Posts: 1,461
    edited April 2009

    Yes please - I did the BRCA testing for my daughter because my FATHER had bc.. my BRCA was neg.  but there is a strong family history and because BRCA was negative my kids are in the clear (no cancer on the other side of the family) UNLESS and this is important to keep your eyes on - they come up with new DNA tests for breast and colon cancers..  in which case my kids will start testing (per my oncologists) 10 years prior to my dx of DCIS..  We ALL need to keep our eyes open for our kids!

  • Jeansbeans
    Jeansbeans Member Posts: 175
    edited April 2009

    Hi Everyone, My daughters and son ages 32,31,29.  I am 4th generation with BC, My mom is now almost a 30 year BC survivor!! She was 57 when dx. my grandmother  died at 53 and my Great grandmother died at 57 of bc. Because of the strong family history I decided to have a Breast MRI done. It took my DR. and myself 3 months of phone calls and letters to Insurance Co., But they finally approved it.  Well. Good thing I did because I had a Mammogram done the same day as the MRI.  My mammo was clean, but the MRI showed 2 areas of IDC.My dh and I flew out to the Mayo Clinic. where I had bilat. mast. with tissue expanders. While there I had genetic testing done, I do not have the BRCA gene, but something is definatly going on that had not been discovered yet.  MY main concern was for my children!  I was told they should start mammos 10 yrs.prior to my DX I was 53 when dx, so that means They don't start till they are 43.  I  told my girls to see their Dr's for mammograms NOW!!!  And an MRI if Ins will pay.  They are as worried as I am .  The only thing we can do as mothers is to keep on top of things and educate our children . MRI's are not recommended unless their are 2 , 1st degree relatives with bc.  If I hadn't been persistant with having an MRI done, I would still be sitting home while cancer was spreading through me.  MY Dr told me it would take years for anything to show up on Mammo.  Gentle hugs to all you wonderful ladies!  Jeanie  

  • Blondee
    Blondee Member Posts: 18
    edited April 2009

    Hello all. I was diagnosed with bc at age 43 which means my dauughter who is now 19 should start getting mammo's at age 33. She had her first gyn appointment at age 18 which gives me some peace of mind because she is getting breast exams from early on. All we can do is be vigilant in terms of our daughters and their breast health. Its very scary but I pray that soon medical science will find a cure for this horrible desease.

  • nash
    nash Member Posts: 2,600
    edited April 2009

    I worry about this all the time. My kids (one boy, one girl) were 5 and 8 when I was diagnosed at age 38. My mom died of bc, my dad died of pancreatic cancer, my grandfather died of bladder cancer, my father-in-law died of prostate cancer, and I have an aunt with colon cancer. Egads.

    Although I tested BRCA negative, I wonder about what sort of crappy genetics I have passed on to my kids. And having lost 3 grandparents in 7 years to the disease, plus Mommy has it, my kids are both terrified of getting cancer. I explained to them that kids usually don't get cancer, so now instead  they worry about getting it as adults. Undecided And frankly, I'm worried for them.

  • GregH
    GregH Member Posts: 3
    edited April 2009

    Hello,

    I have twin daughters that are now 14.  Just a thought here, has anyone heard anything about possible causes for bc?  Personally I wonder if some of the hormones being used in the dairy industry and perhaps the livestock and poultry industries have anything to do with there being so much bc today.  My wifes PCP said he rarely used to see bc cases but has had 6 since November including my wife.  I'm not overly organic or anything, but we have changed to organic milk and meat from free range animals that are not injected with hormones.  This might be the wrong forum for this, but just wondering what you all think.   

  • Anonymous
    Anonymous Member Posts: 1,376
    edited April 2009

    GregH - I think you are right on track.  However, I started buying organic milk and usually bought organic or non hormone added chicken when my kids were born (11 and 9).  Here I am with BC!

    As I have hormone positive breast cancer, I will only buy organic meat and dairy from now on.  I am doing conventional treatment but saw a naturopathic doctor who said organic meat and dairy only.  I also had my vitamin and minerals tested and am low in Vitamin D.

    There is no one in my family that has had breast cancer, or cancer in general (we get heart disease). I do think there are some environmental factors and personally Vitamin D plays a role in my case (I live in Seattle).

    Good luck - don't know what type of  breast cancer your wife has, but this board is great.

    Susan

  • shelloz1
    shelloz1 Member Posts: 405
    edited April 2009

    I was amazed at how little I knew about my family's history of cancer (until I was diagnosed with BC) and needed the information for the BRCA testing.  It turns out that on my side of the family we have a lot of colon cancer, stomach cancer, there is also breast cancer, prostrate cancer, thyroid cancer and malanoma.  On my husband's father's side there is colon cancer (his dad passed away from this) not sure who else, but amazingly on his mother's side (she is Safardic) there is no one who had cancer.  It's interesting to see that on the Ashkanaz side there is so much cancer, kind of makes you wonder. 

    Anyway, I have 3 children (2 girls ages 20 and 15 and 1 boy aged 17), I am so worried about them, since there seems to be so much cancer in the family history.  My 20 year old has already started going to the gyno for breast check up's and she is also doing pelvic US every 6 months.  I was tested negative for BRCA, but with all the other cancer's in the family, that actually doesn't make me feel that much at ease.  My 20 year old has recently told me that she is suffering from depression, she is worried that she will have cancer.  I have tried to help her overcome this, explained that worrying at this stage is not healthy for her (and unfortunately won't help her anyway) and that she needs to try and go on with her life and not think about it.

    I wish that they would find a way to stop cancer, it's amazing how many people have had it (will have it, etc).

    Shelley

  • GregH
    GregH Member Posts: 3
    edited April 2009

    Hi aprilgirl1,

     We live in Yakima so vitamin D usually isn't a problem!  My wife has early stage IDC, 9mm, stage 1, grade 3 and ER+/PR+, Her2+.  We went to Seattle Cancer Care Alliance for a second opinion and wound up doing what they suggest.  She is taking Taxol and Herceptin for 12 weeks, then radiation and Herceptin every 3 weeks for the rest of the year.  This regimen isn't as aggressive as the Onc in Yakima wanted, but my wife was very afraid of Carboplatin and as such it was the right treatment for her.  Personally I would have preferred TCH, but I'm not the one in the infusion chair, and the SCCA Onc really seemed to know what he was doing.

    It seems that the hormones are given to animals to make them grow faster so that they can get them to market quicker and that equals more profit.  The fact that cancer cells are rapidly dividing cells and these animals are given the hormones in order to get their cells to divide more rapidly thus growing more rapidly seems kind of scary to me.  And with the dairy cows being given hormones to induce more milk production and the breast being an organ that's primary purpose is to produce milk, that seems scary to me too.  I also think that maybe it's more important for us to limit these factors for our children because they are growing much more rapidly than we adults are (except for my stomach that is) and so perhaps are more susceptable to having this affect their physiology than adults might be.  I don't really know if any of this makes sense or is true, but I intend to look into it further. 

    Thanks for getting back to me and I hope things are going well for you.

    Greg

  • REKoz
    REKoz Member Posts: 590
    edited April 2009

    Just adding what my Onc. told me my daughters (27, 24) should do which absolutely confirms JeansBeans experience. My mother (age 77, 3 yrs ago) and now me at age 53 is most certainly within the criteria for risk. Mom did not have to BRCA test but I did and it was negative. I'm convinced further research will uncover more genetic variables as no one can talk me out of thinking my girls ARE at high risk.

    Anyway, my Onc.'s opinion is that the girls each get a baseline MRI at age 30. Earlier would be OK with me but the point is, it's the MRI and not an initial mammo that will be their starting point.

    In regard to the hormonals in particularly diary and meat, organic is all I will buy now and have stressed same to my daughters. Highly hormonal positive makes me think that my past history of LOVING milk and drinking it by the gallons as it was a "good" thing was in fact a great aide in developing this cancer. Same could be said for the Irish meat and potato upbringing I had and passed on to them! It's hard for them to fully grasp how to undo everything they learned. Just as it was for me. I just pray that they never have to find out the hard way like I did!  And I try not to dwell on my anger that they put out and APPROVE so many carcinogenic products to begin with. There has to be a multitude of people that think we are somehow "protected" as I thought my whole naive life!

    God Bless us all!

    Ellen

  • shelloz1
    shelloz1 Member Posts: 405
    edited April 2009

    Ellen,

    I have to wonder, I am ER/PR - (not hormonal related) so how would milk have any bearing on me?  Not only that but I rarely drink milk and don't eat much dairy (never really have).  I do wonder though, after reading your life in your hands, she makes some valid points about cows milk and dairy.  Asian women have a much lower rate of breast cancer (they don't drink milk and are not dairy eaters), so maybe there is something to be said about it.  I wonder what is it that is affecting Ashanazi's and not Safardic people?  It seems especially so in Colon and stomach cancer's even more.

    I live in Israel, I'm not sure about the vitamin D here, but I don't think it would be the source.  Other than my aunt (on my mother's side) no one else in the family ever had breast cancer (and her daughters thank g-d have not had cancer, I am the only one).  We have had a lot of cancer in the family (so many kinds). 

    I believe in fate, I think that no matter what I would have done, I probably would have ended up getting bc.  The other day I was having a discussion with a rabbi, he said something that I don't know if I believe, but perhaps it's true.  He believes that we all had past lives (we have been here before) and that when we come back we are supposed to correct the wrongs we did and perhaps also be punished for our sins.  Although I find it hard to believe, maybe it explains why things happen to people when we can't find any other explanation.  When I see babies and young children with cancer, I can't find ANY thing that can explain why it happened to them, what could they have done wrong in this life?  So maybe it really was something from a past life, but it still seems so wrong.

    Okay, that's my philosophy lesson 101 :-)

    Shelley

    Shelley

  • Carolina59
    Carolina59 Member Posts: 232
    edited April 2009

    My only consolation is that my only child, my dd, who was conceived before my BC diagnosis and is now 4 y.o., was conceived via egg donation. My BRCA2 came back with a variant of uncertain significance, but my paternal GM died of metastatic BC, and my paternal 1st cousin was diagnosed with BC at 43 (18 years NED).

    I will still advise my dd to be vigilant about her healthcare, but with any luck she has not inherited any faulty BC genes.Please God.

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