How Effective Are Vitamins?--NYTImes article

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I read this in the NYTimes today, and it definitely is causing me to rethink what I do with my vitamin supplements. I need time to ponder this...

February 17, 2009 Well

Vitamin Pills: A False Hope?

By TARA PARKER-POPE

Ever since the Nobel Prize-winning biochemist Linus Pauling first promoted "megadoses" of essential nutrients 40 years ago, Americans have been devoted to their vitamins. Today about half of all adults use some form of dietary supplement, at a cost of $23 billion a year.

But are vitamins worth it? In the past few years, several high-quality studies have failed to show that extra vitamins, at least in pill form, help prevent chronic disease or prolong life.

The latest news came last week after researchers in the Women's Health Initiative study tracked eight years of multivitamin use among more than 161,000 older women. Despite earlier findings suggesting that multivitamins might lower the risk for heart disease and certain cancers, the study, published in The Archives of Internal Medicine, found no such benefit.

Last year, a study that tracked almost 15,000 male physicians for a decade reported no differences in cancer or heart disease rates among those using vitamins E and C compared with those taking a placebo. And in October, a study of 35,000 men dashed hopes that high doses of vitamin E and selenium could lower the risk of prostate cancer.

Of course, consumers are regularly subjected to conflicting reports and claims about the benefits of vitamins, and they seem undeterred by the news - to the dismay of some experts.

"I'm puzzled why the public in general ignores the results of well-done trials," said Dr. Eric Klein, national study coordinator for the prostate cancer trial and chairman of the Cleveland Clinic's Glickman Urological and Kidney Institute. "The public's belief in the benefits of vitamins and nutrients is not supported by the available scientific data."

Everyone needs vitamins, which are essential nutrients that the body can't produce on its own. Inadequate vitamin C leads to scurvy, for instance, and a lack of vitamin D can cause rickets.

But a balanced diet typically provides an adequate level of these nutrients, and today many popular foods are fortified with extra vitamins and minerals. As a result, diseases caused by nutrient deficiency are rare in the United States.

In any event, most major vitamin studies in recent years have focused not on deficiencies but on whether high doses of vitamins can prevent or treat a host of chronic illnesses. While people who eat lots of nutrient-rich fruits and vegetables have long been known to have lower rates of heart disease and cancer, it hasn't been clear whether ingesting high doses of those same nutrients in pill form results in a similar benefit.

In January, an editorial in The Journal of the National Cancer Institute noted that most trials had shown no cancer benefits from vitamins - with a few exceptions, like a finding that calcium appeared to lower the recurrence of precancerous colon polyps by 15 percent.

But some vitamin studies have also shown unexpected harm, like higher lung cancer rates in two studies of beta carotene use. Another study suggested a higher risk of precancerous polyps among users of folic acid compared with those in a placebo group.

In 2007, The Journal of the American Medical Association reviewed mortality rates in randomized trials of antioxidant supplements. In 47 trials of 181,000 participants, the rate was 5 percent higher among the antioxidant users. The main culprits were vitamin A, beta carotene and vitamin E; vitamin C and selenium seemed to have no meaningful effect.

"We call them essential nutrients because they are," said Marian L. Neuhouser, an associate member in cancer prevention at the Fred Hutchinson Cancer Research Center in Seattle. "But there has been a leap into thinking that vitamins and minerals can prevent anything from fatigue to cancer to Alzheimer's. That's where the science didn't pan out."

Everyone is struggling to make sense of the conflicting data, said Andrew Shao, vice president for scientific and regulatory affairs at the Council for Responsible Nutrition, a vitamin industry trade group. Consumers and researchers need to "redefine our expectations for these nutrients," he said. "They aren't magic bullets."

Part of the problem, he said, may stem from an inherent flaw in the way vitamins are studied. With drugs, the gold standard for research is a randomized clinical trial in which some patients take a drug and others a placebo. But vitamins are essential nutrients that people ingest in their daily diets; there is no way to withhold them altogether from research subjects.

Vitamins given in high doses may also have effects that science is only beginning to understand. In a test tube, cancer cells gobble up vitamin C, and studies have shown far higher levels of vitamin C in tumor cells than are found in normal tissue.

The selling point of antioxidant vitamins is that they mop up free radicals, the damaging molecular fragments linked to aging and disease. But some free radicals are essential to proper immune function, and wiping them out may inadvertently cause harm.

In a study at the University of North Carolina, mice with brain cancer were given both normal and vitamin-depleted diets. The ones who were deprived of antioxidants had smaller tumors, and 20 percent of the tumor cells were undergoing a type of cell death called apoptosis, which is fueled by free radicals. In the fully nourished mice, only 3 percent of tumor cells were dying.

"Most antioxidants are also pro-oxidants," said Dr. Peter H. Gann, professor and director of research in the department of pathology at the University of Illinois at Chicago. "In the right context and the right dose, they may be able to cause problems rather than prevent them."

Scientists suspect that the benefits of a healthful diet come from eating the whole fruit or vegetable, not just the individual vitamins found in it. "There may not be a single component of broccoli or green leafy vegetables that is responsible for the health benefits," Dr. Gann said. "Why are we taking a reductionist approach and plucking out one or two chemicals given in isolation?"

Even so, some individual vitamin research is continuing. Scientists are beginning to study whether high doses of whole-food extracts can replicate the benefits of a vegetable-rich diet. And Harvard researchers are planning to study whether higher doses of vitamin D in 20,000 men and women can lower risk for cancer and other chronic diseases.

"Vitamin D looks really promising," said Dr. JoAnn E. Manson, the chief of preventive medicine at Brigham and Women's Hospital and an investigator on several Harvard vitamin studies. "But we need to learn the lessons from the past. We should wait for large-scale clinical trials before jumping on the vitamin bandwagon and taking high doses."

Comments

  • LisaF
    LisaF Member Posts: 200
    edited February 2009

    Thanks for sharing this.  Very interesting.

  • vivre
    vivre Member Posts: 2,167
    edited February 2009

    According to Dr. Ray Strand, who wrote "What your Doctor does not know about nutrition may be killing you", the problem with all of these studies is that they tend to isolate one or two supplements at a time. He contends that if we only supplement one nutrient, we are still leaving our bodies vulnerable in other areas. He is an MD who was becoming more and more frustrated that he could not help his patients with the drugs he was taught to prescribe. Then he had a patient who cured herself with nutrition and supplements so he began to explore it. He contends, that while eating nutriously is the best defense, our food supply is so depleted in nutrients, because our soil is depleted, that it is impossible to get all we need from food. So whenever we see these studies on one supplement, we need to look at the bigger picture. As doctor Strand shows in casestudies of his patients, we need to throw the whole book at our health. While eating nutritiously is the key, supplements that surpass the FDA requirements are needed to complete our health.

  • crazy4carrots
    crazy4carrots Member Posts: 5,324
    edited February 2009

    I've read a couple of other articles essentially saying the same thing.  My feeling is that, unless you're taking regular medication (such as an AI that is known to potentially cause osteoporosis due to the lack of estrogen), and if you regularly eat a healthy diet (fresh, not processed foods) then you really shouldn't require a multivitamin or mineral supplement.  Everything should be coming from the food you consume.  The exception seems to be Vitamin D, especially for those of us living a fair ways north of the equator.

    There are 3 problems, however:  #1 is that MDs don't learn about nutrition in med school, so can't really advise us on what supplements we need if we're taking certain medications; #2 is that we're swamped with ads for supplements on tv, over the internet, in magazines, and every time we enter a drugstore -- which makes us feel we SHOULD be taking them all! and #3 is that most regular blood tests don't check for a lack of vitamins or minerals, so we have to exhibit symptoms first.  Better to try to prevent the symptoms of illness first.

    Just my thoughts!

    Linda 

  • desdemona222b
    desdemona222b Member Posts: 776
    edited February 2009

    Well this study is about multi-vitamins, among other things. 

    Pasted from AnneW's post above:

    The latest news came last week after researchers in the Women's Health Initiative study tracked eight years of multivitamin use among more than 161,000 older women. Despite earlier findings suggesting that multivitamins might lower the risk for heart disease and certain cancers, the study, published in The Archives of Internal Medicine, found no such benefit.

  • desdemona222b
    desdemona222b Member Posts: 776
    edited February 2009

    I read about another study done about a year ago that indicated that no positive effect can be detected from multi-vitamins whatsoever - in fact, the particular study I'm remembering specifically stated that the stats for people with death from heart disease were actually higher for the groups that took multivitamins, although there is not necessarily any correlation there. 

    The main point of these studies is the fact that wholesome food and a good diet provides the vitamins the system needs - fresh fruit, veggies, whole grains, and healthy fats most efficiently nourishes the system.

    You can tell a huge difference in how you feel if you start eating 5 serving of fruits and veggies every single day along with whole grains and healthy oils.  I did it last year, then fell off the wagon, but it resolved a lot of problems I was having and I felt great.

  • Dejaboo
    Dejaboo Member Posts: 2,916
    edited February 2009

    I have been working hard on trying to make my Diet very healthy (fruits, Veggies, Fiber, Good fats, etc)

    And I figure I will eventually phase out some of my Vitamins.  Not D3 or Calcium though.

    I find it very hard to get in the recommended sevings that we should.  Just 5 fruits a day fill me up!

    Maybe we/I can start a thread on healthy eating & how tos for those of us like me that are finding it hard to switch...And keep this thread about the Vitamin article.

    Pam

  • desdemona222b
    desdemona222b Member Posts: 776
    edited February 2009

    I don't think it can hurt to take a multivitamin every day for good measure, although I personally think they're just not necessary unless you have some sort of condition such as anemia, which a physician will treat with iron supplements. 

    Physicians are always happy to direct you to a licensed nutritionist if you have reservations.

  • dlb823
    dlb823 Member Posts: 9,430
    edited February 2009

    Anne ~ What we rarely know is what form of vitamins they use.  A 100% whole & natural Vitamin C supplement with all the naturally occuring micronutrients?  Or a cheap, isolated ascorbic acid?  (I suspect the latter.)  Also, we don't know what condition the research subjects were in, or what kind of diet they followed or their other lifestyle choices.  A mostly synthetic One-A-Day brand type of vitamin on top of a typical American diet probably isn't going to yield any measureable improvement.  And then there's always the question of who is funding the research and their motivation.  Personally, while I don't believe any amount of nutritional supplementation alone can keep us from getting bc or cure it, and while I also think there may be some valid concern for overdoing antioxidants while on chemo, I put very little stock in most of the research because you have only to look at people who follow healthy lifestyles that include good supplementation to know there's a benefit.

  • desdemona222b
    desdemona222b Member Posts: 776
    edited February 2009

    Hi, Deja -

    It IS hard to eat 5 fruits and veggies a day, isn't it?  You have to make a point of it and keep track. 

    Last year I went on Weight Watchers Core Plan, something I loved because there are many, many things you can eat on that plan that you don't have to count points on.  I lost 20 lbs in about 2 1/2 months.  I felt so good while I was eating like that!  I had to start my day with fresh fruit every morning. 

    Any type of hot cereal, oats, and corn meal are considered whole grains on this diet and do not count.  So, every morning I would make a bowl of oatmeal from rolled oats and cook it with a banana or I would add a small container of applesauce afterwards.  That way I had one fruit down for the day.  Often I would eat another bowl of oatmeal at night when I was feeling the urge to snack.  The diet requires 2 tsps of healthy oil a day (olive or canola), so I would also put a couple of tsps in the oatmeal on days I wasn't planning on using that oil in a meal.  You honestly cannot taste the oil.

    Since I'm over 50, the diet also calls for 3 servings of non-fat dairy a day, which actually helps you lose weight.  A study in Sweden indicates that the calcium molecules bind with fat and help you excrete the fat without your body absorbing calories from it.  (Of course you still have to make sure you're not eating too much fat.)

    I HAVE to go back to that way of eating.  It's hard getting all those fruits and veggies down, but about 2 weeks after doing that religiously, you'll feel a lot better.

  • Anonymous
    Anonymous Member Posts: 1,376
    edited February 2009

    In countries where breast and other cancers are lowest, there is a very low percentage of people taking supplements. They achieve health through diet, lifestyle, exercise, not supplements from Big Supplementa (the alternatives' answer to Big Pharma).

    The best way to get a couple/3 servings of fruits/veggies a day is make a smoothie. My favorite is: I start with 4 oz of unsweetened organic apple juice and 4 oz of green tea. I add about 1/2 cup of frozen organic blueberries, 1/2 cup of frozen organic strawberries, and about 1/3 cup of frozen organic raspberries (all the berries are from Trader Joes). If I have an overripe banana, I throw that in the blender too. It makes a tall glass for 2 people.

  • desdemona222b
    desdemona222b Member Posts: 776
    edited February 2009

    That's true, LJ, and another thing people don't realize is that a half cup of most veggies is a serving.  That's not as much as some people might think of as a "serving."  I believe fresh, leafy salad veggies are one cup per serving, so a large salad will provide 2-3 servings as well.

  • FloridaLady
    FloridaLady Member Posts: 2,155
    edited February 2009

    People please research what has happen to our food chain in the last forty or so years.  Seed have been genetically altered so they are pest resistance, pretty or have longer shelf life.  Nothing about insuring nutrition!  Many food now grow in the US other countries will not except because of what we have done to them.  Most thing are not pulled off the plant way before they mature to insure long delivery problems.  Less time on the vine the less nutrition. The big thing is we have totally delete our soils from the over use of fertizlers that we have very poor soil conditions. 

    I eat what in the store because I have to.  But it no way believe it is the same things our parents were eating thirty to forty years ago.

    Just for the monitor's will post the research.

  • FloridaLady
    FloridaLady Member Posts: 2,155
    edited February 2009

     63% of America's crops now use these seeds.

    Genetically modified (GM) foods are food items that have had their DNA changed through genetic engineering. Unlike conventional genetic modification that is carried out through conventional breeding and that have been consumed for thousands of years, GM foods were first put on the market in the early 1990s. The most common modified foods are derived from plants: soybean, corn, canola, and cotton seed oil. For example, a typical GM Food could be a strawberry that must survive in cold climates. Cultured cells from the strawberry and of a similar plant that is more resilient to cold are grown. Researchers use the Polymerase Chain Reaction method of replication to create millions of the desired DNA fragment safely and accurately. Researchers then insert these fragments, along with RNA "instructions" into plasmids or modified protein capsules, called "protein coats," much like those of viruses. These plasmids, along with DNA ligase and other enzymes, are injected into the cultured strawberry cells. The enzymes sever the DNA of the strawberry at a specific precoded point, and the fragment of 'frost resistance' DNA is placed in the gap. DNA ligase then binds the severed DNA ends. The cells of the strawberry plant grown from culture are now more likely to be resistant to frost.[1][2]

    Genetically engineered crops and foods are controversial. These commonly focus on the long-term health effects for anyone eating them, environmental safety, labeling and consumer choice, intellectual property rights, ethics, food security, poverty reduction, environmental conservation, and potential disruption or even possible destruction of the food chain. Proponents claim the technology to be a boon for the human race, while critics believe it to be a potential or actual health or ecological disaster.

    [edit] Development

    The first commercially grown genetically modified whole food crop was the tomato (called Flavr Savr), which was made more resistant to rotting by Californian company Calgene.[3] Calgene was allowed to release in 1994 without any special labeling.[4] It was welcomed by consumers who purchased the fruit at two to five times the price of regular tomatoes. However, production problems[3] and competition from a conventionally bred, longer shelf-life variety prevented the product from becoming profitable. A variant of the Flavr Savr was used by Zeneca to produce tomato paste which was sold in Europe during the summer of 1996.[5] The labeling and pricing were designed as a marketing experiment, which proved, at the time, that European consumers would accept genetically engineered foods.

    Currently, there are a number of foods of which a genetically modified version exists.

    FoodProperties of the genetically modified varietyTrade nameCompanyModificationPercent in USPercent in world
    SoybeansResistant to herbicidesRoundup Ready,MonsantoHerbicide resistant gene taken from bacteria inserted into soy bean89%TBA
    Corn, fieldResistant to pesticides (tolerating crop spray - this way a farmer can use amounts of pesticides which would normally kill the plant, without harming it)Roundup Ready,MonsantoNew gene added/transferred into plant genome60%TBA
    CottonPest-resistant cottonTBA New gene added/transferred into plant genome83%TBA
    Hawaiian PapayaVariety is resistant to the Papaya Ringspot Virus.TBA New gene added/transferred into plant genome+50%TBA
    TomatoesVariety that does not rot (degrade) as fast - the genetically modified (gm) tomatoes do not produce the enzyme that normally causes tomatoes to rot and degrade.E.g. FlavrSavr First genetically modified tomatoes contained genes that made them resistant to antibiotics. After concern from doctors and the medical community, tomatoes were then genetically modified in a different way.Taken off the market due to consumer protest.TBA
    Potatoes    TBATBA
    Rapeseed (Canola)Resistance to certain pesticides (tolerating crop spray)Bt New gene added/transferred into plant genome75%TBA[6]
    Sugar caneResistance to certain pesticides (tolerating crop spray)TBA New gene added/transferred into plant genomeTBATBA
    Sugar beetResistance to certain pesticides (tolerating crop spray)Roundup Ready,MonsantoNew gene added/transferred into plant genomeTBATBA
    Sweet cornProduces its own insecticide (a toxin to insects, so insect attacks are less likely)Bt corn Insect-killing gene added to the plant. The gene comes from the bacteria Bacillus thuringiensis.TBATBA
    RiceGenetically modified to contain high amounts of Vitamin A (beta-carotene)"Golden rice" Three new genes implanted: two from daffodils and the third from a bacteriumTBATBA

    In addition, various microorganisms have been genetically engineered to produce aspartame, amino acids, and various chemicals. [7]

    A list of FDA Approved GMO Foods is public information on the FDA website[8]

    View a list of commercialized GM crops in the US as of July 2007[9]

    [edit] Growing GM crops

    Between 1995 and 2005, the total surface area of land cultivated with GMOs had increased by a factor of 50, from 17,000 km2 (4.2 million acres) to 900,000 km2 (222 million acres), of which 55 percent were Brazil.

    Although most GM crops are grown in North America, in recent years there has been rapid growth in the area sown in developing countries. For instance in 2005 the largest increase in crop area planted to GM crops (soybeans) was in Brazil (94,000 km2 in 2005 versus 50,000 km2 in 2004.)[10] There has also been rapid and continuing expansion of GM cotton varieties in India since 2002. (Cotton is a major source of vegetable cooking oil and animal feed.) It is predicted that in 2008/9 32,000 km2 of GM cotton will be harvested in India (up more than 100 percent from the previous season). Indian national average cotton yields of GM cotton were seven times lower in 2002, because the parental cotton plant used in the genetic engineered was not well suited to the climate of India and failed. The publicity given to transgenic trait Bt insect resistance has encouraged the adoption of better performing hybrid cotton varieties, and the Bt trait has substantially reduced losses to insect predation. Though controversial and often disputed, economic and environmental benefits of GM cotton in India to the individual farmer have been documented.[11][12]

    In 2003, countries that grew 99% of the global transgenic crops were the United States (63%), Argentina (21%), Canada (6%), Brazil (4%), China (4%), and South Africa (1%).[13] The Grocery Manufacturers of America estimate that 75% of all processed foods in the U.S. contain a GM ingredient[14] . In particular, Bt corn, which produces the pesticide within the plant itself is widely grown, as are soybeans genetically designed to tolerate glyphosate herbicides. These constitute "input-traits" are aimed to financially benefit the producers, have indirect environmental benefits and marginal cost benefits to consumers.

    In the US, by 2006 89% of the planted area of soybeans, 83% of cotton, and 61% maize were genetically modified varieties. Genetically modified soybeans carried herbicide tolerant traits only, but maize and cotton carried both herbicide tolerance and insect protection traits (the latter largely the Bacillus thuringiensis Bt insecticidal protein). In the period 2002 to 2006, there were significant increases in the area planted to Bt protected cotton and maize, and herbicide tolerant maize also increased in sown area.[15]

    However, several studies have found that genetically modified varieties of plants do not produce higher yields than normal plants.[16]

    [edit] Coexistence and traceability

    In many parts of the world such as the European Union, Japan, Malaysia and Australia consumers demand labelling so they can exercise choice between foods that have genetically modified, conventional or organic origins.[17][18] This requires a labelling system as well as the reliable separation of GM and non-GM organisms at production level and throughout the whole processing chain.[17][18] Research suggests that this may prove impossible, reason why GM opponents use the 'genie out of a bottle' analogy.

    For traceability, the OECD has introduced a "unique identifier" which is given to any GMO when it is approved. This unique identifier must be forwarded at every stage of processing.

    Many countries have established labelling regulations and guidelines on coexistence and traceability. Research projects such as Co-Extra, SIGMEA and Transcontainer are aimed at investigating improved methods for ensuring coexistence and providing stakeholders the tools required for the implementation of coexistence and traceability.

    The GM food controversy is a dispute over the advantages and disadvantages of genetically modified food crops. See Genetically modified food controversies.

    [edit] Controversy

    Main article: GM food controversy

    Some scientists[19] argue that there is more than enough food in the world and that the hunger crisis is caused by problems in food distribution and politics, not production, so people should not be offered food that may carry some degree of risk.[20][21]

    A media firestorm erupted in 1999 when scientist Árpád Pusztai found that consumption of potatoes genetically modified to contain lectin had negative intestinal effects on rats.[22] As a consequence he became the victim of a smear campaign but was eventually vindicated.[23] The results he argued that the effects could not be attributed entirely to lectin, which is known to have toxic effects, and stated that "other parts of the GM construct, or the transformation, could have contributed to the overall effects".[22] He appeared on television where he said that the government and companies were using the population as guinea pigs. Europeans were outraged, and within a week every major food company on the continent including McDonalds, Nestlé and Burger King, all committed to not purchase GM foods. Later, the Royal Society released a review of the which concluded that the work was flawed and that no conclusions should be drawn from it.[24]

    The attitude towards GM foods only got worse after outbreaks of Mad Cow Disease weakened consumer trust in government regulators, and protesters rallied against the introduction of Monsanto's "Roundup Ready" soybeans.[citation needed] The next GM crops included insect-resistant cotton[25][26] and herbicide-tolerant soybeans[27] both of which were commercially released in 1996. GM crops have been widely adopted in the United States. They have also been extensively planted in several other countries (Argentina, Brazil, South Africa, India, and China) where the agriculture is a major part of the total economy. Other GM crops include insect-resistant maize and herbicide-tolerant maize, cotton, and rapeseed varieties.

    Genetic modifications often have significant unforeseen consequences, both in the initially modified organisms and their environments. For example, certain strains of maize have been developed that are toxic to plant eating insects (see Bt corn). It has been alleged those strains cross-pollinated with other varieties of wild and domestic maize and passed on these genes with a putative impact on Maize biodiversity.[28] Subsequent to the publication of these results, several scientists pointed out that the conclusions were based on experiments with design flaws. It is well known that the results from polymerase chain reaction (PCR) methods of analysing DNA can often be confounded by sample contamination and experimental artifacts. Appropriate controls can be included in experiments to eliminate these as a possible explanation of the results - however these controls were not included in the methods used by Quist and Chapela.[29] After this criticism Nature, the scientific journal where this data was originally published concluded that "the evidence available is not sufficient to justify the publication of the original paper".[30] More recent attempts to replicate the original studies have concluded that genetically modified corn is absent from southern Mexico in 2003 and 2004.[31] Also in dispute is the impact on biodiversity of the introgression of transgenes into wild populations.[32] Unless a transgene offers a massive selective advantage in a wild population, a transgene that enters such a population will be maintained at a low gene frequency. In such situations it can be argued that such an introgression actually increases biodiversity rather than lowers it.

    Activists and many scientists opposed to genetic engineering say that with current recombinant technology there is no way to ensure that genetically modified organisms will remain under control, and the use of this technology outside secure laboratory environments represents multiple unacceptable risks to both farmed and wild ecosystems.

    Potential impact on biodiversity may occur if herbicide-tolerant crops are sprayed with herbicide to the extent that no wild plants ('weeds') are able to survive. Plants toxic to insects may mean insect-free crops. This could result in declines in other wildlife (e.g. birds) which feed on weed seeds and/or insects for food resources. The recent (2003) farm scale studies in the UK found this to be the case with GM sugar beet and GM rapeseed, but not with GM maize (though in the last instance, the non-GM comparison maize crop had also been treated with environmentally-damaging pesticides subsequently (2004) withdrawn from use in the EU).

    Although some scientists have claimed that selective breeding is a form of genetic engineering,[33] (e.g., maize was modified from teosinte, dogs have evolved with human intervention over the course of tens of thousands of years from wolves), others assert that modern transgenesis-based genetic engineering is capable of delivering changes faster than, and sometimes of different types from, traditional breeding methods.[34]

    Proponents of current genetic techniques as applied to food plants cite hypothetical benefits that the technology may have, for example, in the harsh agricultural conditions of Africa. They say that with modifications, existing crops could possibly be able to thrive under the relatively hostile conditions providing much needed food to their people. Proponents also cite golden rice and golden rice 2, genetically engineered rice varieties (still under development) that contain genetically-modified elevated vitamin A levels. Some hope that this rice may alleviate vitamin A deficiency that contributes to the death of millions and permanent blindness of 500,000 annually.[35]

    Proponents claim that genetically-engineered crops, although patented for economic benefit, are not significantly different from those modified by nature or humans in the past. They also argue that modified crops are as safe, or even safer, than those created through such time-tested methods. There is gene transfer between unicellular eukaryotes and prokaryotes. They argue that animal husbandry, Food irradiation and crop breeding are also forms of genetic engineering that use artificial selection instead of modern genetic modification techniques. It is politics, they argue, not economics or science, that causes their work to be closely investigated, and for different standards to apply to it than those applied to other forms of agricultural technology.

    Proponents also believe the technology could possibly prove harmless because species or genetic barriers have been crossed in nature in the past, sometimes utilizing other better time-tested and natural methods. An oft-cited example is today's modern red wheat variety, which is the result of two natural crossings made long ago. It is made up of three groups of seven chromosomes. Each of those three groups came from a different wild wheat grass. First, a cross between two of the grasses occurred, creating the durum wheats, which were the commercial grains of the first civilizations up through the Roman Republic. Then a cross occurred between that 14-chromosome durum wheat and another wild grass to create what became modern red wheat at the time of the Roman Empire.

    [edit] Economic and political effects

    • Some opponents of current genetic engineering claim that increasing use of GM in major crops has caused a major power shift in agriculture towards Biotechnology companies, which, they claim, are gaining more control over the production chain of crops and food, and over the farmers that use their products, as well.[citation needed]
    • Many proponents of some current genetic engineering techniques claim that it will lower pesticide usage and has brought higher yields and profitability to many farmers, including those in developing nations.[36] A few genetic engineering licenses allow farmers in less economically developed countries to save seeds for next year's planting.[citation needed]
    • In August 2003, Zambia cut off the flow of Genetically Modified Food (mostly maize) from UN's World Food Programme. This left a famine-stricken population without food aid.
    • In December 2005 the Zambian government changed its mind in the face of further famine and allowed the importation of GM maize.[37] However, the Zambian Minister for Agriculture Mundia Sikatana has insisted that the ban on genetically modified maize remains, saying "We do not want GM (genetically modified) foods and our hope is that all of us can continue to produce non-GM foods."[38][39]
    • In April 2004 Hugo Chávez announced a total ban on genetically modified seeds in Venezuela.[40]
    • In January 2005, the Hungarian government announced a ban on importing and planting of genetic modified maize seeds, although these were agreed authorized by the EU.[41]
    • On August 18, 2006, American exports of rice to Europe were interrupted when much of the U.S. crop was confirmed to be contaminated with unapproved engineered genes, possibly due to accidental cross-pollination with conventional crops.[42] The U.S. government has since declared the rice safe for human consumption, and exports to some countries have since resumed, but in the past years more crops have started to cross-pollinate which leaves a problem that is yet to be solved.[citation needed]

    [edit] Intellectual property

    Main article: Monsanto Canada Inc. v. Schmeiser

    Enforcement of patents on genetically modified plants is often contentious, especially because of gene flow. In 1998, 95-98 percent of about 10 km2 planted with canola by Canadian farmer Percy Schmeiser were found to contain Monsanto's patented Roundup Ready gene although Schmeiser had never purchased seed from Monsanto.[43] The initial source of the plants was undetermined, and could have been through either gene flow or intentional theft. However, the overwhelming predominance of the trait implied that Schmeiser must have intentionally selected for it. The court determined that Schmeiser had saved seed from areas on and adjacent to his property where Roundup had been sprayed, such as ditches and near power poles.[44]

    Although unable to prove direct theft, Monsanto sued Schmeiser for piracy since he knowingly grew Roundup Ready plants without paying royalties(Ibid). The case made it to the Canadian Supreme Court, which in 2004 ruled 5 to 4 in Monsanto's favor.[43][44] The dissenting judges focused primarily on the fact that Monsanto's patents covered only the gene itself and glyphosate resistant cells, and failed to cover transgenic plants in their entirety. All of the judges agreed that Schmeiser would not have to pay any damages since he had not benefitted from his use of the genetically modified seed.

    In response to criticism, Monsanto Canada's director of public affairs stated that "It is not, nor has it ever been Monsanto Canada's policy to enforce its patent on Roundup Ready crops when they are present on a farmer's field by accident...Only when there has been a knowing and deliberate violation of its patent rights will Monsanto act."[45] Currently Percy Schmeiser spends a large amount of his time traveling and speaking about how Monsanto ruined his career as a farmer. He also talks about the possible harms of genetic modification and why others in addition to himself should be protesting it.

    [edit] Future developments

    Future envisaged applications of GMOs are diverse and include drugs in food, bananas that produce human vaccines against infectious diseases such as Hepatitis B,[46] metabolically engineered fish that mature more quickly, fruit and nut trees that yield years earlier, foods no longer containing properties associated with common intolerances, and plants that produce new plastics with unique properties.[47] While their practicality or efficacy in commercial production has yet to be fully tested, the next decade may see exponential increases in GM product development as researchers gain increasing access to genomic resources that are applicable to organisms beyond the scope of individual projects. Safety testing of these products will also at the same time be necessary to ensure that the perceived benefits will indeed outweigh the perceived and hidden costs of development. Plant scientists, backed by results of modern comprehensive profiling of crop composition, point out that crops modified using GM techniques are less likely to have unintended changes than are conventionally bred crops.[48][49]

    [edit] Health Risks

    Several people are dying from the allergic reactions that are caused by the addition of the harmful pesticide chemicals, and added genes in the GM foods/crops. Currently there are only a few dozen peer reviewed studies completed on the health effects of genetically modified foods. The results of many of these studies strongly challenges the industry and government standard of substantial equivalence.

    Gene Transfer:

    As of January 2009 there has only been one human feeding study conducted on genetically modified foods. The study involved seven human volunteers who had their small intestines removed. These volunteers were to eat GM Soy to see if the DNA of the GM soy transferred to the human gut bacteria. Researchers identified that three of the seven volunteers had transgenes from GM soy transferred into their gut bacteria.[50]

    "This transgene was stable inside the bacteria and appeared to produce herbicide-tolerant protein... In the only human feeding study ever conducted on GM crops, long standing assumptions that genes would not transfer to human gut bacteria were overturned. The findings should prompt immediate comprehensive follow-up tests to determine the implications for health among both the general population and at-risk groups."[51]

    Allergies:

    Since 2004 some cotton workers in India have experiencing allergic reactions to only Bt cotton, and not to other conventional varieties. The longer the workers were exposed to the genetically modified Bt cotton the more sever their symptoms were. An investigation concluded that reactions included: "mild to sever itching.. in severe cases eyes also became red, and swollen"[52] One doctor reported that he had seen approximately 150 cases of allergies to Bt Cotton in 2005, and another 100 in 2004. [53]

    In the mid 1990's Pioneer Hi-Bred began to genetically modify a soybean that would take a gene from a Brazil nut in the hopes that soy would increase the production of of the amino acid methionine. While this particular new crop was being designed for animal feed, as the case of StarLink corn clearly showed that food only for animal consumption will undoubtedly enter the human food supply. Pioneer Hi-Bred decided to test the new GM soybean with the Brazil nut gene for allergens as many people are allergic to Brazil nuts. To the companies surprise in three separate tests (radioallergosorbent testing, immunoblotting, and skin-prick testing) all studies showed that individuals allergic to Brazil nuts were also allergic to the new gm soybean.[54] "In trying to build a better soybean the company had made a potentially deadly one."[55]

    In 1999 soy allergies in the United Kingdom increased from 10%-15% in a single year. Coincidentally GM soy entered the UK shortly before 1999. One study using skin prick test showed that of the 49 subjects 13 individuals experienced a positive reaction to non-GM soy, 8 individuals reacted to the GM soybeans, and "one patient had a positive skin test result to GMO soybeans only."[56] This study again proves that a particular genetically modified food can cause an allergic reaction in a person who does not have an allergy to the natural variety

  • FloridaLady
    FloridaLady Member Posts: 2,155
    edited February 2009

    This is from the The Center of Food Safety

    Genetically Engineered Food

    The genetic engineering of plants and animals is looming as one of the greatest and most intractable environmental challenges of the 21st Century. Already, this novel technology has invaded our grocery stores and our kitchen pantries by fundamentally altering some of our most important staple food crops.

    By being able to take the genetic material from one organism and insert it into the permanent genetic code of another, biotechnologists have engineered numerous novel creations, such as potatoes with bacteria genes, "super" pigs with human growth genes, fish with cattle growth genes, tomatoes with flounder genes, and thousands of other plants, animals and insects. At an alarming rate, these creations are now being patented and released into the environment.

    Currently, up to 45 percent of U.S. corn is genetically engineered as is 85 percent of soybeans. It has been estimated that 70-75 percent of processed foods on supermarket shelves--from soda to soup, crackers to condiments--contain genetically engineered ingredients.

    Anumber of studies over the past decade have revealed that genetically engineered foods can pose serious risks to humans, domesticated animals, wildlife and the environment. Human health effects can include higher risks of toxicity, allergenicity, antibiotic resistance, immune-suppression and cancer. As for environmental impacts, the use of genetic engineering in agriculture could lead to uncontrolled biological pollution, threatening numerous microbial, plant and animal species with extinction, and the potential contamination of non-genetically engineered life forms with novel and possibly hazardous genetic material.

    Despite these long-term and wide-ranging risks, Congress has yet to pass a single law intended to manage them responsibly. This despite the fact that our regulatory agencies have failed to adequately address the human health or environmental impacts of genetic engineering. On the federal level, eight agencies attempt to regulate biotechnology using 12 different statutes or laws that were written long before genetically engineered food, animals and insects became a reality. The result has been a regulatory tangle, where any regulation even exists, as existing laws are grossly manipulated to manage threats they were never intended to regulate. Among many bizarre examples of these regulatory anomalies is the current attempt by the Food and Drug Administration (FDA) to regulate genetically engineered fish as "new animal drugs."

    The haphazard and negligent agency regulation of biotechnology has had serious consequences for consumers and the environment. Unsuspecting consumers by the tens of millions are being allowed to purchase and consume unlabeled genetically engineered foods, despite a finding by FDA scientists that these foods could pose serious risks. And new genetically engineered crops are being approved by federal agencies despite admissions that they will contaminate native and conventional plants and pose other significant new environmental threats. In short, there has been a complete abdication of any responsible legislative or regulatory oversight of genetically engineered foods. Clearly, now is a critical time to challenge the government's negligence in managing the human health and environmental threats from biotechnology.

    CFS seeks to prevent the approval, commercialization or release of any new genetically engineered crops until they have been thoroughly tested and found safe for human health and the environment. CFS maintains that any foods that already contain genetically engineered ingredients must be clearly labeled

    ***Thought of this stuff makes me sick to think what our kids are eating and the long term effects. This is what we talk about when you could have disease from environmental issues.

  • FloridaLady
    FloridaLady Member Posts: 2,155
    edited February 2009

    Where the h*ll is the FDA?  Noted congress has yet to pass a single law intended to manage this! How many years has this been going on?

    Flalady

  • FloridaLady
    FloridaLady Member Posts: 2,155
    edited February 2009

    Are Biotech Foods Safe to Eat?

    Most Americans have eaten genetically modified foods without knowing it, but are they safe?
    WebMD Feature

    Genetically modified food has quietly become second nature in the U.S., and it may surprise you just how many foods you are eating that you never knew contained a genetically modified ingredient.

    Experts say 60% to 70% of processed foods on U.S. grocery shelves have genetically modified ingredients. The most common genetically modified foods are soybeans, maize, cotton, and rapeseed oil. That means many foods made in the U.S. containing field corn or high-fructose corn syrup, such as many breakfast cereals, snack foods, and the last soda you drank; foods made with soybeans (including some baby foods); and foods made with cottonseed and canola oils could likely have genetically modified ingredients. These ingredients appear frequently in animal feed as well.

    If this shocks you, a new USDA-funded survey shows you're not alone. Researchers from the Food Policy Institute at Rutgers' Cook College found that only 52% of Americans realized that genetically modified foods are sold in grocery stores and only 26% believed that they have ever eaten genetically modified foods -- a modest 6% increase since 2001.

    But what exactly is genetically modified food? Is it safe to eat? Why isn't it labeled in the U.S.? The European Union and the U.S. are boxing it out.

    The U.S. government's position: Genetically engineered crops are safe, resist disease better, and can provide much-needed food in starving nations.

    The EU position: Keep it out. We prefer organic, which is much healthier. The risk of genetically modified foods to health and the environment outweigh the benefits. Only the multinational biotech companies will benefit, dominating the world food supply and squeezing out traditional farmers.

    The U.S. is the largest producer of genetically modified crops.

    More than a dozen countries around the world have latched on to the technology, including Argentina, Canada, China, Australia, India, and Mexico.

    'Frankenfood' Fears

    The term genetically modified food (also known as biotech or genetically engineered food) refers to crop plants that have been modified in the laboratory to enhance desired traits, such as resistance to herbicides or improved nutritional content. Experts say this science, like any other, has no guarantees. Risks include:

    • Introducing allergens and toxins to food
    • Accidental contamination between genetically modified and non-genetically modified foods
    • Antibiotic resistance
    • Adversely changing the nutrient content of a crop
    • Creation of "super" weeds and other environmental risks

    Benefits include:

    • Increased pest and disease resistance
    • Drought tolerance
    • Increased food supply

    Is Regulation Too Soft?

    So you might ask, what's the big deal? The U.S. government wouldn't allow a product on the market without strict testing and approval, right? It seems genetically modified foods are a bit of a scientific anomaly, a creature that U.S. regulation agencies aren't quite sure how to efficiently manage.

  • vivre
    vivre Member Posts: 2,167
    edited February 2009

    I use to think my European friends were just finding another way to bash us when they turned up their noses at American food. Then I tasted a strawberry from a market in France. I had never truly tasted a strawberry before. I made a recipe for creme brulee that tasted totally different than what my French friend had made, because our dairy is pasterized, even though they invented this process. One of the reasons American is having such an epidemic of obesity is because of all the preservatives in prepared foods, msg, which is pure poison, and all the hormones given to animals, which we end up eating. All these things fuel cancer too.

    Even when we try to eat healthy, we get too much bad stuff in our foods, and not enough of the good stuff.

    I think I am going to have to double my garden this summer and can my fruits and veggies the way my grandmothers did. Maybe that is why they lived into their 80's and 90's and never got cancer!

  • FloridaLady
    FloridaLady Member Posts: 2,155
    edited February 2009

    Vivre heirloom seeds not this GM stuff.  You can get them off the Internet.

    Go girl

    Flalady

  • FloridaLady
    FloridaLady Member Posts: 2,155
    edited February 2009

    Additional Soil Damage Caused by Synthetic Fertilizers and CAFO Manure
    Although synthetic fertilizers add necessary nutrients to cropland, unlike manure, they fail to restore organic matter to the soil and have been shown to adversely affect soil productivity. Regular use of synthetic fertilizers causes long-term depletion of organic matter, soil compaction, and degradation of overall soil quality.xxivOver-fertilization also causes important minerals such as calcium, magnesium, and potassium to gradually leach out of the soil.xxv

    Manure from CAFOs can also degrade soil quality. For instance, since heavy metals are added to animal feed in order to promote growth, manure can contain trace amounts of metals such as arsenic, copper, selenium, and zinc.xxvi The high concentration of manure in CAFO lagoons enable heavy metals to accumulate in the surrounding environment, contaminating soil, poisoning wildlife, and polluting groundwater.xxvii

    CAFO manure also contains disease-causing pathogens and residues of hormones and antibiotics. When untreated manure is applied to fields, these substances can be washed over and through soil, contaminating groundwater and surface water.

    For more information about the damages caused by CAFOs, see the Environment and Public Health Threats pages.

    Sustainable Nutrient Management
    Sustainable nutrient management techniques allow farmers to maintain healthy, productive soils for crops without degrading the environment.

    Small-scale sustainable farms are able to recycle nutrients by fertilizing their crops using compost and manure produced by their livestock. While CAFOs raise hundreds or thousands of animals, producing far too much manure to be safely absorbed by the surrounding land, sustainable farms only raise small numbers of animals, creating just enough manure to fertilize crops without polluting the environment or jeopardizing human health.

    This enables sustainable farms to avoid using harmful chemical fertilizers. Natural fertilizers (fertilizers composed entirely of organic materials such as manure and compost) have been shown to cause much less pollution than synthetic fertilizers. One ten-year study of maize fields revealed that fields treated with chemical fertilizers released 60% more nitrates into groundwater than fields treated with natural fertilizers.xxviii

    The USDA currently requires all Certified Organic produce to be grown without synthetic fertilizers. Likewise, organic meats must come from animals that were fed organic crops grown without chemical fertilizers.

  • Dejaboo
    Dejaboo Member Posts: 2,916
    edited February 2009

    Thanks desdemona222b

    That makes it sound s little easier.

    LJ13-

    I even bought French Vanilla yogurt this weekend to make smoothies with- although I had already for gotten that!   I dont really like cold drinks during the winter...But thought I should give them a try...A didnt even think about how many Fruit servings were in one.

    Pam

  • Anonymous
    Anonymous Member Posts: 1,376
    edited February 2009

    Pam, I don't make as many during the winter either. But they sure are good in summer !

  • bmdaley
    bmdaley Member Posts: 292
    edited February 2009

    Hi Anne & everyone -- It appears that many of the studies in this article are NOT relevant to our situation. There is vigorous controvery in the medical community about the benefits/harms of antioxidants and vitamin supplement use by breast cancer patients.

    For example, its taken many years, but even oncologists (at least mine) are now recommending use of Vitamin D3. I wish I would have known about D3 when I was first diagnosed as there have been numerous studies now showing correlation between low Vitamin D levels and increased cancer recurrence (ex. http://www.asco.org/ASCO/Abstracts+%26+Virtual+Meeting/Abstracts?&vmview=abst_detail_view&confID=55&abstractID=31397)

    In addition, it should be noted that nutritionists have been critical of how some of these studies are conducted. Some believe that most commonly available multivitamins don't have much nutritional value, or that the vitamin levels used in the studies are so low as to make the study meaningless.

    Regarding the studies in the NYT article. The first three studies mentioned in the article (paragraphs 3 & 4) tracked whether vitamins caused an increased or decreased risk of cancer. We already have cancer so that study is NOT relevant to us. The primary topic of the editorial and related articles from the January National Cancer Insitute Journal is also related to whether vitamins prevent/cause cancer (link to editorial http://jnci.oxfordjournals.org/cgi/content/extract/101/1/2). Some of the other studies cited may be relevant to our situation and am in process of trying to track them down, so encourage everyone to do your research. We really should only be concerned about studies concerning breast cancer as every cancer is different. 

    There is a lot of research already done and going on about the effect that vitamins/antioxidants can have on breast cancer. Its a huge project to sort through it all. But some nutritionists follow breast cancer closely and may be able to help. 

  • AccidentalTourist
    AccidentalTourist Member Posts: 365
    edited February 2009

    I did wonder as to whether cancer cells get fed by some of the 'good for us' nutrients like any other cells.  I do try to take most of nutrients from food but do take selenium, kelp and vitamin D in a supplement form. 

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