bioidentical hormones for menopause
Has anyone tried biodentical hormone replacement for menopause? Is it safe for breast cancer survivors, and can it be taken with tamoxifen? I see my oncoligist next month and plan on asking him about it.
Comments
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Gwen
FWIW, I was taking 'bio-identical' hormones, and I still got bc... and since we have already HAD bc, I don't think it would be wise to take ANY estrogen now.
good luck to you!
Harley -
A group of us raised this issue on another post and decided to read up on this and exchange views on a new post. The book we are going to discuss is Dr Lee's book 'What doctors don't tell you about breast cancer' (not proper reference, from memory). He suggests that there are three kinds of estrogen and not all are implicated in BC. I am not arguing that he is right but if he is this might have impliations for us. Harley how long have you been on 'bio identical' homones before you were diagnosed?
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Oprah just did an entire show on this yesterday...you can find links and information on her website. Most doctors have NO idea about bio-identical hormones. Good luck finding one who has any real knowledge. I highly recommend reading not only Dr. Lee's books, but also Dr. Christiane Northrup's book...the Wisdom of Menopause.
AccidentalT is right...there are three types of estrogen...two bad and one good.
Educate yourself!
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I have read Dr. Lee's book on bioidentical and breast cancer and find it very interesting. It mentions that there are 3 estrogen hormones (estradiol, estrone and estriol) Estradiol and estrone are the more potent forms and cause breast and uterine cell growth. According to the book, estriol is a much weaker form of estrogen, which based on some small studies, does not appear to cause breast/uterine cell growth. According to the book, estriol may be a safe alternative for breast cancer survivor's, for meopause, but only if monitored by a Dr.
I myself am looking into testoserone pellet therapy only, as I have had an ooph and have low levels of all hormones estrogen, progest and testosterone. Pellet therapy delivers a very low dose of testosterone daily, somwhat like a women has in her 20s or 30s. Apparently low-dose testosterone can help a menopausal women with hot flashes, libido, vag dryness and bone loss. There is a small chance of androgen symptoms like acne, facial hair ect. but these differ for each women and the test dose can be lowered, per my Dr's nurse. - I am more than willing to try it, given my menopause symptoms. Alot of breast cancer survivor's in my area are using testosterone pellet therapy only with good results.
I saw the Oprah show too. Very informative.
Julie
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Hi Julie, thanks for the info! did you have any side effects from the ooph?(I am considering having this) are you taking an AL? or where you able to avoid because of the ooph?
thanks,
Lorraine
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Thanks for the info!
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I have ER positive BC and I would personally not risk taking bioidentical hormones. I was interested in this post, as I am hoping to discourage my aunt [also ER+ - we were diagnosed one month apart] from jumping on the bioidentical bandwagon. I just know that I would not want to add any further percentage of risk to possible recurrence than has already been assessed for me.
There is an article regarding bioidentical hormones which came out this month, written by Joanne Pinkerton, an OB/GYN who also was voted one of the Best Doctors in America for 2007-2008. I believe it addresses many questions about this topic.
http://www.obgmanagement.com/article_pages.asp?aid=7187
Believe me, I am as frustrated as so many are, with hot flashes and dry skin and the emotional aspects of menopause. I wish the safe antedote was out there. I am hoping that a major change in diet will help ameliorate some of the symptoms for me.
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Wow - thanks whippetmom - great information. I've had so many questions about it all. I just always wonder about the 'if it sounds too good to be true..."
Amy
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I also have opted to take low dose testosterone, in a compounded cream form. For years I took it with an aromatase inhibitor, Femara, to make sure none of the testosterone would be converted to estradiol to fuel breast cancer, or, in my case, endometriosis as well. The testosterone helps my arthritis and stopped my migraines as well as improving my energy level, hot flashes, vaginal atrophy, cystitis, and to top it all off people started telling me I looked 10 years younger. That's not even mentioning how it resurrects the libido after surgical menopause. Can you tell how much I like it???
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Bio-identials work for women...but for those of us who have BC, well we are a different group! And the trick with bioidenticals... you have to go to a doctor and you have to get YOUR hormones tested. You can't just self prescribe what hormones you may or may not need. I've been familiar with them for years...and have seen how they have helped so many women. But AGAIN, we are walking in uncharted territory...especially with being diagnosed with BC.
Find a PROFESSIONAL who has KNOWLEDGE of bioiodenticals. They are hard to find, but they are out there. As with anything else...do your own research!
Here is a link to some scientific studies you can look up
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Very interesting,Julie,
I'm going to look into this before my next onc appt. I have had an oomp and complete hysterectomy so help with vaginal dryness would be good. Right now I use a pea sized amount of Estrace cream which helps but it makes me a uneasy.
Karol
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Hi Lorraine
I was on tamox and zolodex shots for 1.5yrs. The zolodex shots had already caused an instant menopause, so when I had the ooph in Feb. 08, the symptoms have been about the same. I am mostly bothered by the hot flashes. Also no libido and vag dryness. I have been on femara for 11 mths and now have joint issues and muscle weakness, as well.
I was 48 when dxed with stage 1/ grade 2/ er/pr+/her2-. I am working with a very reputable Dr. here and have had blood and saliva tests. She also monitors all pts for uterine problems while on bioidenticals, including an annual transvaginal ultrasound. And she needed my oncologist's approval, before she will start the testosterone.
Rescue
That is exciting that you had such good results! I have my appointment Feb. 11th. I am looking forward to seeing if this therapy will provide me with some relief.
Julie
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whippetmom
I agree with you 100%! I won't take ANY estrogen. I agree that we women who have had bc are another group altogether, and we have to be careful.
While I don't think that the 3 years I took 'bio-identical' hormones CAUSED my bc, it certainly FED my bc, since I had the ER+/PR+ type.
I took PROMETRIUM and used Vivelle dot estrodial patch.
I also have read lots of different opinions, but MOST conventional drs. think that Dr Lee is a quack. That is JMHO, FWIW.
Harley
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I think it's a lot more acceptable for someone on tamoxifen to have estrogen cream if vaginal dryness is a big issue.
Then you're targeting the hormone at tissue that needs it.
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Rose,
I am conflicted about using estrogen cream. I feel that I really need something to help with that er... side effect, and even though my onc. says it's ok, he won't write the Rx for it, so I worry still about using estrogen. Maybe when I switch to an AI, I'll take the plunge and try it. I have a feeling that those AI's will make the dryness problem unbearable, so I may have to just bite the bullet!
Harley -
Harley, I was told that by the time my cancer was discovered I probably had it at least five years. It is therefore conceavable that you already had your cancer before you started the bio-identical hormones. I never took them, have no family history and still got ER+ and PR+ cancer so it is difficult to know whether bio-identicals either caused or fed it. Of course we don't know that they didn't either. Dr Lee was written off as quack and he well may be but he devoted his life's work to this and quotes many studies that support his views particularly regarding estriol. His book is worth reading even if you don't agree with everything he says becasue he explains better than anyone else certain processes which interfere with estrogen becoming damaging to our health (like what happens when we excercise and how that helps). I think if other doctors were more interested in finding out what else (apart from medications which have such damaging side effects) can be helpful we would not be searching for information ourselves.
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There are other well known doctors in addition to Dr. Lee who are educated on bioidenticals:
Dr. Christiane Northrup (who was just on Oprah) http://www.drnorthrup.com/
Dr. Erika Schwartz http://www.drerika.com/images/pdf/MedClinicsNorthAmerica.pdf
Dr. Uzzi Reiss http://www.uzzireissmd.com/book_naturalhormone.html
Dr. David Zava
Dr. Sherrill Sellman http://www.whatwomenmustknow.com/
Do your RESEARCH!
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AccidentalTourist,
Yes, I know that I had bc BEFORE I even used the bio-identical hormones, as my surgeon told me that we have bc for 8 to 10 years before we can even feel a lump. Nonetheless, estrogen feeds the ER+ type of bc that I had, so it did feed my tumor, no doubt about that.
I don't blame myself. I was dx'd with Premature Ovarian Failure at age 35, and I had researched my condition before finally deciding to try bio-idential hormones. This is why I think I may know a little bit about this topic. NONE of my drs. knew what to do with me. But, since I was still very young, and having hot flashes and night sweats, I felt that I had to do something.
I agree that if others in the medical field would research the cause of cancer and the effects of ALL treatments, including alternative as well as Rx drugs, maybe one day there would be a CURE for this horrible disease.
Harley
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Hi Ladies,
Well I have reached my witt's end with the chemopause side effects and have done many weeks of research, and more research. I have spoken with the local compounding pharmacist who was able to give some pointers to help get me started. I spoke with my Onc about my request and even had supporting trials and data to support my request. He understood but would not support me or write a prescription. I didn't expect him too, but did want to touch base with him and share my view and if he had any input that would help me. I know am going to visit my Gyno who said on the phone that she would write me a script and work with me on finding that special combo. I am so excited as if it were xmas, just cannot take the side effects anymore, it has now been about 15 months since last period.........thank you chemo!!
I would like to hear from those that have used or are using bioidentical hormones and have had BC. Did your Onc or Gyno write the scripts? what was your follow-up, if any? how has it made a difference to your life?
thanks
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I was diagnosed with DCIS in situ..had lumpectomy, radiation, now trying to decide whether to go back on estrogen- i was using cream..going to try the ring...but would love to do the bioidentical hormones. My surgeon and radiaologist and gynocologist all told me I could use the cream and ring as it was such a small amount. The first surgeon I went to but didn't use told me i had to get off the cream and take tamoxifen. My surgeon Idid use and radiologist said the tamoxifen probably was not necessary..the benefits for me at my stage of life did not outweight the risks for the small percent of benefit it would give me. It taught me that i need to shop around. The first sugeon I went to was a general surgeon...the second is a leading breast cancer researcher...they have the lastest clinical trial research...know about newer innovative procedures with fewer side effects
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I was on bio identical estrogen when I got my dx. Had to stop immediately. Am not allowed to go back on ever.
Bio identical is not natural by the way. It is manufactured in a lab. The only way we could ever have natural estrogen is if we got it from other women and we never would. Bio identical is a bit misleading.
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