Has anyone else had incredibly dry skin?
Hi all,
I'm over a month out of chemo, but still have skin so dry I look like I'm training to become an alligator handbag. Literally! My skin is peeling off in large flakes; it's really disgusting, and it doesn't look like the end is in sight. Is this an unusual reaction? If not, how long does it last, and has anyone found a lotion or cream that combats this horrible reptilian condition?
Thanks,
Annie Caiman Skin
Comments
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Well, I have incredibly dry skin, but I've never had chemo. I have psoriasis, and the docs are arguing if I have CREST. (This is a type of scleroderma, which means 'hard skin'. If I have it, its at an early stage.)
I need to use something like every hour. For me, ointments stick a little better than creams, but they don't 'work in' as well.
For me, I prefer the generic Eucerin when I'm in the mood for something water soluble. I use vaseline when I'm into oily, and I like Cornhusker's (the active ingredient is glycerine, I believe), which is very pleasant, but doesn't last very long.
Chemos can definitely cause skin stuff. What chemos are/were you on?
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Hi Leaf,
Thanks so much for your response. I had 4 X Taxotere and Avastin, and 2 X AC + Avastin, and 2 X AC alone. The dry skin started almost immediately, but seems to be getting progressively worse. I'm wondering if the chemo provoked some sort of auto-immune disorder since I've read that can be one of the consequences of the Taxotere. I'll try the Cornhusker's to see if it works for me too -- does it smell good or like cows' udders?
Hugs,
Annie
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Well, Avastin doesn't seem to be associated with dry skin in a Pubmed search.
I don't know if you have had any rash, blisters, etc. before this peeling skin. I also do not know if that is of any importance.
But it sounds like for Taxotere-it can be full of skin reactions. It sounds like peeling skin can be part of a scenario for which you need to contact your doctor - it sounds like normally it starts with a rash/eruptions, then gets peeling skin. But of course I am not a physician or dermatologist of any kind.
Taxotere recommendations at this citation say to contact your doctor for ...peeling skin (severe)
http://www.mayoclinic.com/health/drug-information/DR601849
This is from the package insert:
p. 19
Cutaneous: Localized erythema of the extremities with edema followed by desquamation has
been observed. In case of severe skin toxicity, an adjustment in dosage is recommended (see
DOSAGE AND ADMINISTRATION section). The discontinuation rate due to skin toxicity
was 1.6% (15/965) for metastatic breast cancer patients. Among 92 breast cancer patients
premedicated with 3-day corticosteroids, there were no cases of severe skin toxicity reported and
no patient discontinued TAXOTERE due to skin toxicity.
http://www.fda.gov/cder/foi/label/2004/020449s028lbl.pdf
I would notify your doctor about this (besides using the cream/oinment/lotion of choice), unless of course you have open sores. In the same package insert it says
p. 30
Cutaneous: rare cases of bullous eruption such as erythema multiforme or Stevens-Johnson
syndrome. Multiple factors may have contributed to the development of these effects.
I have never been up close and personal with a cow, so I don't know personally about Bag Balm, though I have seen it regularly recommended by quilters. Some say they don't like Bag Balm's slight medicinal scent.
Cornhusker's does have a slight scent (it does contain Fragrance). To me it smells slightly like soap, but I have been told I have a poor sense of smell. Cornhusker's is oil free, so less likely to stain.
My generic Eucerin Cream contains lanolin which causes allergies in some people. I don't know if the brand Eucerin does. Some people like Cetaphil, which is also water-in-oil.
Now, I'm just new to the field of dry skin. This Pubmed article implies that it may be necessary to tailor therapy to the specific cause. But it does say that petroleum jelly has an immediate effect on repairing the stratum corneum. This paper is from Sweden, so I am assuming its less likely to have pharmaceutical bias, particularly if they are promoting petroleum jelly in some cases. http://www.ncbi.nlm.nih.gov/pubmed/14572299
It sounds like there is more research to be done. with the treatment of dry skin. http://www.ncbi.nlm.nih.gov/pubmed/17300239
So, in conclusion, it seems like I was hasty in recommending anything, as we don't have a lot of scientific data. One abstract recommended petroleum jelly as repairing one layer of the skin, but it is oily.
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My skin had always been oily but chemo dried me out good. I used lubriderm, and oil of olay nighttime creme. Also while wet used a lanalin oil to dry off. Try to keep moisturized .
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Leaf, thanks so much for all the research and info. I really appreciate it. It sounds as though the Taxotere might be behind this, even though I've not had it for months (one of the sites you cite says reactions can occur months or even years later). It's limited to my lower legs, and does not involve open sores or edema. Simply very dry, peeling skin. I'm trying some of DH's prescription dry skin cream and will speak to the oncologist about it when I see him next week.
Thanks again,
Annie
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Just be cautious about the type of lotion you use - many contain parabens which are types of preservatives (allows for longer shelf life) and parabens once absorbed into the body act as hormone disrupters - ie estrogens - so if you are ER+ beware!
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if you can take vit. E capsules...i have found they help the skin
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