Genetic study at New York Presbyterian

Reckless

Hello,

I was getting bloodwork done today at New York Presbyterian. While I was waiting to be called by the lab technician, a woman passed around fliers to be enrolled in a free genetic study. It’s a long-term study where they will take blood and saliva samples and provide the participants with info on their ancestry, genetic mutations, pathways for medications uptake, etc. Unfortunately, lost the flier with the website address and phone number. Does anybody living in any happen to know what this study might be called or who to contact for info at NYP? I am not sure if it’s this study https://www.nyp.org/news/wcm-nyp-illumina-collaborate-on-scalable-clinical-whole-genome-sequencing-initiative and do not know who to contact to find out.Thank you!

Reckless

I think it's https://www.joinallofus.org/faq Not sure if it’ worth joining it if I am already on 23andme and got tested for BRCA and 20 other BC mutations…

Jelson

Reckless - I note you mention that the NYP study includes pathways for medication uptake. I don't think 23andMe covers it well if at all. Pharmacokinetics/Pharmagenetics are some of the terms used in this area and the papers/clinical studies are way beyond my comprehension. There has been in the past much discussion on BCO whether the metabolic pathways for tamoxifen are the reason it helps some BC patients better than others and why certain SSRIs also seem to impact the effectiveness of tamoxifen. I think Cyp2D6 refers to the pathway for tamoxifen. This issue of how individual genetics impacts how we react to drugs and the interaction of drugs which follow the same metabolic pathways applies to many of the drugs BC patients and actually anyone takes. Depending on how detailed the NYP study is and how much they share with you about your results, this could be valuable info for you going forward with medication prescribed for conditions other than BC.

Reckless

Thank you Jelson! The study is actually run by NIH. The issue is that they are not providing timeline of when they will be getting back to participants with results, could be a matter of years. I’ll look intoother ways of getting info on pathways.