Tamoxifen and vaccine

speace

Hello, has anyone heard of tamoxifen lessening the effect of the covid vaccine ? I'm on the 10 year plan of tamoxifen with 4 years to go. My dentist told me tamoxifen can lessen the covid vaccine. I dont know if I necessarily believe this so I thought I'd come ask here . Thanks in advance for any help.

ctmbsikia

Your dentist is incorrect I would say.

Hormone therapy, such as tamoxifen, letrozole, anastrozole or exemestane, does not typically affect your immune system. Therefore, it shouldn't reduce the effectiveness of the vaccine, and it should be safe to have the vaccine if you're taking one of these treatments.

Some people have asked if it's safe to have the AstraZeneca vaccine if they are on hormone therapy. This follows news stories about a rare type of blood clot in a small number of people who had this vaccine. Blood clots can be a side effect of tamoxifen.

However, as far as we're aware there's no increased risk of blood clots in people who have the AstraZeneca vaccine while taking hormone therapy.

NOTE: AstaZeneca is not approved for use in the US at this time.

speace

Thank you , I didn't think so , im sure I would of heard from my oncologist or one of my doctors about the tamoxifen/covid vaccine thing if that was the case. I have had my 2 doses of Moderna since February, so far so good. Thanks again!

marie12

"Tamoxifen protects breast cancer patients from COVID-19: first evidence from real world data" Tamoxifen protects breast cancer patients from ... - Research Square that concluded:

Tamoxifen treated BC patients showed a reduced rate of hospitalization and strikingly no fatalities for COVID-19. In vitro experiments confirmed a protective role of tamoxifen while an increased susceptibility to SARS-CoV-2 infection of ER+ cells treated with fulvestrant was observed.

speace

Thank you