Keytruda + Chemotherapy

dreaberk

Hi, I am new to this forum and would love to hear from anyone in a similar situation. My first breast cancer diagnosis was in 2013: Stage 2 IDC, GRADE 2 ER, PR + (95%) Her2 -, had DMX and ACT chemo. Fast forward to March this year, I found a marble size lump under right breast. New cancer, triple negative ki67 90%. I started Carboplatin and Gemzar and qualified for Keytruda as my tumor expresses PD-L1. Has anyone else been on Keytruda with chemo for early stage TNBC? And how long did your Dr. say it takes for Keytruda to start working? Thanks!

Moderators

HI dreaberk, and welcome to Breastcancer.org,

We're so very sorry for the reasons that bring you here, but we're really glad you've found us and decided to join and post. You're sure to find our Community an amazing source of advice, information, encouragement, and support -- we're all here for you!

You may get some responses here soon, but we wanted to also suggest you use our search function (in the navigation bar on the left of your screen) with keyword Keytruda to find others who might be discussing this treatment.

In addition, you may find the following articles from our main Breastcancer.org site helpful:

• Immunotherapy for Early-Stage Triple-Negative Breast Cancer: Understanding What Appear to Be Conflicting Results
• Adding Keytruda to Chemotherapy Before Surgery for Early-Stage, Triple-Negative Breast Cancer Improves Response to Treatment
• Immunotherapy Keytruda for Early-Stage Triple-Negative Breast Cancer: Better pCR and Lower Recurrence Rates: ESMO 2019 Coverage

We hope this is helpful and we look forward to seeing you around the Community! Let us know if you need anything at all.

--The Mods

S3K5

I started Keytruda with Carbo + Gemzar but this is in metastatic setting (liver and bone mets). I didn't find any forum for this 3-drug combo, so I guess we could exchange our experiences on this forum.

dreaberk how are you doing on this regimen? Do you get immunotherapy once in 3 weeks? Hope the side effects are tolerable.

BrinkOfEternity

I had neoadjuvant Keytruda + Abraxane and in about 1-2 months my 3cm hard tumor shrank to the point I couldn't feel it anymore. When I had my UMX after 3 months of chemo they found 0.6cm of IDC left, I believe. Hope this helps…